当前位置： SCI文献检索 > VIROLOGY期刊下所有文献 > Relationships between 80 human papillomavirus genotypes and different grades of cervical intraepithelial neoplasia: association and causality.

Relationships between 80 human papillomavirus genotypes and different grades of cervical intraepithelial neoplasia: association and causality.

Abstract：

:To clarify the causal relationship between human papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN), we analyzed 386 unfixed biopsy specimens by blot hybridization at Tm -40 degrees C, targeting 38 skin and 42 genital HPVs. By the recognition of PstI, BanI, and MspI cleavage patterns, single genital, but no skin's HPVs were identified with more than 10 copies per cell in 354 CIN (88 CIN I, 94 CIN II, and 172 CIN III). HPVs 40, 42, 43, 54, 62, or 71 was found in 10 CIN I, while HPVs 18, 30, 39, 51, 56, 59, 66, 68, 69, or 82 was found in 35 CIN I, 20 CIN II, or 8 CIN III. On the other hand, HPVs 16, 31, 33, 35, 52, 58, or 67 was identified in 43 CIN I, 74 CIN II, or 164 CIN III. The results are strongly indicative that most genital HPVs have potency to induce CIN I; however, HPV 16 and its closely related types are able to efficiently induce CIN III. We discuss the definition of causal HPV for CIN with regard to viral prevalence and viral load.

journal_name

Virology

journal_title

Virology

authors

Matsukura T,Sugase M

doi

10.1006/viro.2001.0865

subject

Has Abstract

pub_date

2001-04-25 00:00:00

pages

139-47

issue

1

eissn

0042-6822

issn

1096-0341

pii

S0042-6822(01)90865-7

journal_volume

283

pub_type

杂志文章

相关文献

VIROLOGY文献大全
  • HIV-1 and two avian retroviral 5' untranslated regions bind orthologous human and chicken RNA binding proteins.

    abstract：:Essential host cofactors in retrovirus replication bind cis-acting sequences in the 5'untranslated region (UTR). Although host RBPs are crucial to all aspects of virus biology, elucidating their roles in replication remains a challenge to the field. Here RNA affinity-coupled-proteomics generated a comprehensive, unbia...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2015.06.001

    authors： Stake M,Singh D,Singh G,Marcela Hernandez J,Kaddis Maldonado R,Parent LJ,Boris-Lawrie K

    更新日期：2015-12-01 00:00:00

  • Active and separate secretion of fiber and penton base during the early phase of Ad2 or Ad5 infection.

    abstract：:Fiber and penton base overproduced in adenovirus (Ad) infected cells can be secreted prior to progeny release and thereby regulate progeny spread. We aimed to investigate the mechanisms of fiber and penton base secretion in Ad2- or Ad5-infected A549 cells. Our flow cytometry analyses detected abundant surface fiber mo...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2017.02.018

    authors： Yan Y,Zhang B,Hou W,Lin H,Rebetz J,Hong SS,Wang Y,Ran L,Fan X

    更新日期：2017-05-01 00:00:00

  • Loss of HIV-specific memory B-cells as a potential mechanism for the dysfunction of the humoral immune response against HIV.

    abstract：:A central, yet unresolved issue in the pathogenesis of HIV disease is the mechanism of antibody perturbation. In this study, HIV-specific memory B-cells were quantified in groups of infected subjects and compared with memory responses to other antigens and antibody titers. HIV-specific memory B-cell responses were vig...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2009.11.003

    authors： Bussmann BM,Reiche S,Bieniek B,Krznaric I,Ackermann F,Jassoy C

    更新日期：2010-02-05 00:00:00

  • Initial and subsequent sites of aster yellows virus infection in a leafhopper vector.

    abstract：:Aster yellows virus (AYV) was recovered from hemolymph, alimentary canal, salivary glands and ovaries, but not from Malpighian tubules, mycetomes, fat body, testes, or brain of viruliferous leafhoppers, Macrosteles fascifrons (Stål). The presence of virus in the tissues was determined by injecting their extracts into ...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(67)90070-0

    authors： Sinha RC,Chiykowski LN

    更新日期：1967-12-01 00:00:00

  • Molecular characterization of Equine Infectious Anemia Viruses using targeted sequence enrichment and next generation sequencing.

    abstract：:Equine infectious anemia virus (EIAV) is responsible of acute disease episodes characterized by fever, anemia, thrombocytopenia and anorexia in equids. The high mutation rate in EIAV genome limited the number of full genome sequences availability. In the present study, we used the SureSelect target enrichment system w...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2019.08.016

    authors： Deshiere A,Berthet N,Lecouturier F,Gaudaire D,Hans A

    更新日期：2019-11-01 00:00:00

  • Efficient production of Hantaan and Puumala pseudovirions for viral tropism and neutralization studies.

    abstract：:Puumala (PUUV) and Hantaan (HTNV) viruses are hantaviruses within the family Bunyaviridae and associated with Hemorrhagic Fever with Renal Syndrome (HFRS) in humans. Little is known about how these viruses interact with host cells, though pathogenic hantaviruses interact with α(v)β(3) integrin. To study host cell inte...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2011.08.012

    authors： Higa MM,Petersen J,Hooper J,Doms RW

    更新日期：2012-02-20 00:00:00

  • Genetic analysis of the SARS-coronavirus spike glycoprotein functional domains involved in cell-surface expression and cell-to-cell fusion.

    abstract：:The SARS-coronavirus (SARS-CoV) is the etiological agent of severe acute respiratory syndrome (SARS). The SARS-CoV spike (S) glycoprotein mediates membrane fusion events during virus entry and virus-induced cell-to-cell fusion. To delineate functional domains of the SARS-CoV S glycoprotein, single point mutations, clu...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2005.06.046

    authors： Petit CM,Melancon JM,Chouljenko VN,Colgrove R,Farzan M,Knipe DM,Kousoulas KG

    更新日期：2005-10-25 00:00:00

  • Paramyxovirus Sendai virus-like particle formation by expression of multiple viral proteins and acceleration of its release by C protein.

    abstract：:Envelope viruses maturate by macromolecule assembly and budding. To investigate these steps, we generated virus-like particles (VLPs) by co-expression of structural proteins of Sendai virus (SeV), a prototype of the family Paramyxoviridae. Simultaneous expression of matrix (M), nucleo- (N), fusion (F), and hemagglutin...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2004.04.019

    authors： Sugahara F,Uchiyama T,Watanabe H,Shimazu Y,Kuwayama M,Fujii Y,Kiyotani K,Adachi A,Kohno N,Yoshida T,Sakaguchi T

    更新日期：2004-07-20 00:00:00

  • Molecular mechanisms of simian immunodeficiency virus SIV(agm) RNA encapsidation.

    abstract：:Primate lentiviruses are composed of several distinct lineages, including human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus SIVagm. HIV-1 and HIV-2 have significant differences in the mechanisms of viral RNA encapsidation. Therefore, the RNA packaging mechanisms of SIVagm cannot be ...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2007.01.030

    authors： Fu W,Prasad VV,Chen J,Nikolaitchik O,Hu WS

    更新日期：2007-06-20 00:00:00

  • Inhibition of vaccinia virus replication by N-(phosphonoacetyl)-L-aspartate: differential effects on viral gene expression result from a reduced pyrimidine nucleotide pool.

    abstract：:The replication of vaccinia virus was reduced by 3 logs in cells that had been treated before and during infection with a concentration of N-(phosphonoacetyl)-L-aspartate (PALA) which lowered the UTP and CTP to 5 and 20% of controls, respectively, without affecting cell viability. The antiviral activity of PALA was re...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.1997.8735

    authors： Katsafanas GC,Grem JL,Blough HA,Moss B

    更新日期：1997-09-15 00:00:00

  • Ultrastructural analysis of the interaction between F-actin and respiratory syncytial virus during virus assembly.

    abstract：:During respiratory syncytial virus (RSV) infection there is a close physical interaction between the filamentous actin (F-actin) and the virus, involving both inclusion bodies and the virus filaments. This interaction appears to occur relatively early in the replication cycle, and can be detected from 8 h post-infecti...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2007.08.007

    authors： Jeffree CE,Brown G,Aitken J,Su-Yin DY,Tan BH,Sugrue RJ

    更新日期：2007-12-20 00:00:00

  • Are the acid-labile interferon alpha and interferon omega-1 identical?

    abstract：:The interferon (IFN) activity found in human leukocyte IFN alpha preparations, autoimmune and AIDS sera, and others was reported to have distinct antigenic and deviating biological properties. This led to its vague designation as acid-labile and thermolabile IFN alpha. However, using specific monoclonal antibodies, th...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(91)90517-f

    authors： Kontsek P,Borecký L,Novák M

    更新日期：1991-03-01 00:00:00

  • Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome.

    abstract：:Severe acute respiratory syndrome coronavirus (SARS-CoV) envelope (E) protein is a viroporin involved in virulence. E protein ion channel (IC) activity is specifically correlated with enhanced pulmonary damage, edema accumulation and death. IL-1β driven proinflammation is associated with those pathological signatures,...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2015.08.010

    authors： Nieto-Torres JL,Verdiá-Báguena C,Jimenez-Guardeño JM,Regla-Nava JA,Castaño-Rodriguez C,Fernandez-Delgado R,Torres J,Aguilella VM,Enjuanes L

    更新日期：2015-11-01 00:00:00

  • Normal replication of vesicular stomatitis virus without C proteins.

    abstract：:The expression of two small basic proteins (C and C') encoded by a second open reading frame of the New Jersey serotype of vesicular stomatitis virus (VSV) P gene was reported previously (Spiropoulou and Nichol, J. Virol., 67, 3103-3110, 1993). Here we found that the Indiana serotype virus also expressed C and C' prot...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.1996.0066

    authors： Kretzschmar E,Peluso R,Schnell MJ,Whitt MA,Rose JK

    更新日期：1996-02-15 00:00:00

  • Antibodies specific for the antigenic domain 1 of glycoprotein B (gpUL55) of human cytomegalovirus bind to different substructures.

    abstract：:Glycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies against human cytomegalovirus, making it an attractive antigen for active and passive immunoprophylaxis. The immunodominant region on gB is the antigenic domain 1 (AD-1), a complex structure which requires a minimal linear amin...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.1996.0040

    authors： Schoppel K,Hassfurther E,Britt W,Ohlin M,Borrebaeck CA,Mach M

    更新日期：1996-02-01 00:00:00

  • Molecular pathways executing the "trophic sentinel" response in HPV-16 E7-expressing normal human diploid fibroblasts upon growth factor deprivation.

    abstract：:In response to oncogenic insults, normal human cells execute a defense response that culminates in cellular suicide, apoptosis. Normal human diploid fibroblasts expressing the human papillomavirus type 16 (HPV-16) E7 oncoprotein are predisposed to apoptosis when they are deprived of growth factors. Even though a domin...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2003.11.008

    authors： Eichten A,Rud DS,Grace M,Piboonniyom SO,Zacny V,Münger K

    更新日期：2004-02-05 00:00:00

  • The endogenous langur type D retrovirus PO-1-Lu and its exogenous counterparts in macaque and langur monkeys.

    abstract：:PO-1-Lu, the endogenous type D retrovirus of langurs (Trachypithecus obscurus) has previously been considered a progenitor to the prototype type D retrovirus, Mason Pfizer monkey virus (M-PMV/SRV-3), that became established in macaque monkeys (Macaca spp.) following a zoonosis. This study reevaluates this hypothesis t...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/s0042-6822(03)00548-8

    authors： Sommerfelt MA,Harkestad N,Hunter E

    更新日期：2003-10-25 00:00:00

  • Capsid is an important determinant for functional complementation of murine leukemia virus and spleen necrosis virus Gag proteins.

    abstract：:In this report, we examined the abilities and requirements of heterologous Gag proteins to functionally complement each other to support viral replication. Two distantly related gammaretroviruses, murine leukemia virus (MLV) and spleen necrosis virus (SNV), were used as a model system because SNV proteins can support ...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2006.10.038

    authors： Lee SK,Boyko V,Hu WS

    更新日期：2007-04-10 00:00:00

  • Transcriptional regulation of the open reading frame 35 encoded by Kaposi's sarcoma-associated herpesvirus.

    abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) is a member of the Gammaherpesvirinae and is causally associated with Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. The KSHV genome encodes over 85 genes; the function of some is entirely unknown. We have characterized the transcriptio...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2007.08.023

    authors： Masa SR,Lando R,Sarid R

    更新日期：2008-02-05 00:00:00

  • Cowpox virus and other members of the orthopoxvirus genus interfere with the regulation of NF-kappaB activation.

    abstract：:NF-kappaB comprises a family of transcription factors that regulate key immune processes. In this study, the effects of orthopoxvirus infection upon the activation of NF-kappaB were examined. During the early phase of infection, cowpox virus can inhibit the induction of NF-kappaB-regulated gene expression by interferi...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.2001.1090

    authors： Oie KL,Pickup DJ

    更新日期：2001-09-15 00:00:00

  • Conserved aromatic residues of the hepatitis B virus Precore propeptide are involved in a switch between distinct dimeric conformations and essential in the formation of heterocapsids.

    abstract：:The Hepatitis B virus Precore protein, present in the secretory pathway as the HBeAg precursor, can associate in the cytoplasm with the Core protein to form heterocapsids, likely to favor viral persistence. Core and Precore proteins share their primary sequence except for ten additional aminoacids at the N-terminus of...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2014.06.013

    authors： Duriez M,Thouard A,Bressanelli S,Rossignol JM,Sitterlin D

    更新日期：2014-08-01 00:00:00

  • The complete genome structure and synthesis of infectious RNA from clones of tomato bushy stunt virus.

    abstract：:The complete sequence of the genome of the cherry strain of tomato bushy stunt virus (TBSV), a member of the tombusvirus group, was determined. A full-length clone of the genome containing a bacteriophage T7 RNA polymerase promoter was assembled from partial cDNA clones. In vitro transcripts of the genome, either with...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(90)90468-7

    authors： Hearne PQ,Knorr DA,Hillman BI,Morris TJ

    更新日期：1990-07-01 00:00:00

  • The Helminthosporium victoriae 190S mycovirus has two forms distinguishable by capsid protein composition and phosphorylation state.

    abstract：:Purified preparations of the Helminthosporium victoriae 190S (Hv190S) virus contain two sedimenting components that differ in capsid structure. The slower sedimenting component (190S-1) contained p88 and p83 as the major capsid proteins; the faster component (190S-2) contained p88 and p78. Previous peptide-mapping stu...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(92)90520-y

    authors： Ghabrial SA,Havens WM

    更新日期：1992-06-01 00:00:00

  • Altered sialylation of CD45 in HIV-1-infected T lymphocytes.

    abstract：:Immunodeficiency caused by HIV infection probably results from profound dysregulation of normal T lymphocyte properties by the virus. Despite description of the virus cytopathicity and numerous modifications in T cell functions, such as perturbation of antigen receptor signaling, CD4 downregulation, and induction of a...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.1994.1124

    authors： Lefebvre JC,Giordanengo V,Doglio A,Cagnon L,Breittmayer JP,Peyron JF,Lesimple J

    更新日期：1994-03-01 00:00:00

  • A subtype of human papillomavirus 5 (HPV-5b) and its subgenomic segment amplified in a carcinoma: nucleotide sequences and genomic organizations.

    abstract：:A subtype of human papillomavirus 5 (HPV-5b) is closely associated with carcinomas in the disease epidermodysplasia verruciformis (EV). The complete genome was cloned from virus particles in benign lesions of a patient with EV and sequenced: it was 7779 nucleotides long and consisted of six open reading frames (ORFs) ...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(91)91013-7

    authors： Yabe Y,Sakai A,Hitsumoto T,Kato H,Ogura H

    更新日期：1991-08-01 00:00:00

  • A highly pathogenic porcine reproductive and respiratory syndrome virus generated from an infectious cDNA clone retains the in vivo virulence and transmissibility properties of the parental virus.

    abstract：:The nucleotide sequence of a highly pathogenic porcine reproductive and respiratory syndrome virus (PRRSV) was determined. Transfection of MARC-145 cells with capped in vitro transcripts derived from a full-length cDNA clone of the viral genome resulted in infectious PRRSV with growth characteristics similar to that o...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2004.04.046

    authors： Truong HM,Lu Z,Kutish GF,Galeota J,Osorio FA,Pattnaik AK

    更新日期：2004-08-01 00:00:00

  • Evidence for replication of cauliflower mosaic virus DNA in plant nuclei.

    abstract：:Cellular organelles of cauliflower mosaic virus-infected turnip plants were isolated, incubated with 32P-labeled deoxyribonucleoside triphosphates and assayed for their ability to synthesize virus-specific DNA. Only nuclei were found to synthesize a labeled DNA product. This DNA migrated during agarose gel electrophor...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(82)90124-6

    authors： Ansa OA,Bowyer JW,Shepherd RJ

    更新日期：1982-08-01 00:00:00

  • Modification of foot-and-mouth disease virus after serial passages in the presence of antiviral polyclonal sera.

    abstract：:Foot-and-mouth disease virus (FMDV) shows a remarkable antigenic variability. Like other RNA viruses, this virus has a high rate of mutation. It has been proposed that selection exerted by the host's antibodies could play a major role in the rapid evolution of FMDV. The present work reports the selection of FMDV antib...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/0042-6822(89)90629-6

    authors： Carrillo EC,Rojas ER,Cavallaro L,Schiappacassi M,Campos R

    更新日期：1989-08-01 00:00:00

  • Sequence analysis of the genome of porcine lymphotropic herpesvirus 1 and gene expression during posttransplant lymphoproliferative disease of pigs.

    abstract：:The porcine lymphotropic herpesvirus 1 (PLHV-1), the first gammaherpesvirus of pigs, has been detected at a high prevalence in healthy pig populations. A porcine gammaherpesvirus has also been detected at high copy numbers in animals suffering from posttransplant lymphoproliferative disease (PTLD). While human PTLD is...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1006/viro.2002.1390

    authors： Goltz M,Ericsson T,Patience C,Huang CA,Noack S,Sachs DH,Ehlers B

    更新日期：2002-03-15 00:00:00

  • Differential evolution of cell-associated virus in blood and genital tract of HIV-infected females undergoing HAART.

    abstract：:PBMC and vaginal cell (VC) viruses were studied from 5 HIV-infected females for the presence of drug-resistance and non-drug resistance associated mutations. A 1318-bp fragment of polymerase gene was amplified from PBMC and VC proviral DNA. Four of the 5 PBMC viruses exhibited drug resistance-associated mutations in r...

    journal_title：Virology

    pub_type： 杂志文章

    doi：10.1016/j.virol.2005.01.030

    authors： Tirado G,Jove G,Reyes E,Sepulveda G,Yamamura Y,Singh DP,Kumar A

    更新日期：2005-04-10 00:00:00