Mucosal enzyme activities in the functioning intestine one and six months after jejuno-ileal by-pass operation for obesity.

abstract：BACKGROUND:Helicobacter pylori plays a key role in production of reactive oxygen metabolites (ROMs). However, the importance of virulent CagA-positive H. pylori strains remains to be determined. The aim of this study was to assess ROMs production in gastric biopsies of patients infected by H. pylori. Results were corre...

journal_title：Scandinavian journal of gastroenterology

authors： Danese S,Cremonini F,Armuzzi A,Candelli M,Papa A,Ojetti V,Pastorelli A,Di Caro S,Zannoni G,De Sole P,Gasbarrini G,Gasbarrini A

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:This study evaluated the specific subset composition of lymphocytes present in Helicobacter pylori-associated gastritis (HAG), since reports so far have led to inconclusive and conflicting results. METHODS:Endoscopic biopsy specimens from 56 patients were studied by quantitative immunohistochemistry using m...

journal_title：Scandinavian journal of gastroenterology

authors： Hatz RA,Meimarakis G,Bayerdorffer E,Stolte M,Kirchner T,Enders G

更新日期：1996-03-01 00:00:00

abstract：:An experimental model of extrahepatic cholestasis in the rat, using a microsurgical technique, is described. Sixteen days postoperatively all of the animals (n = 10) were alive and had hepatomegaly, splenomegaly, jaundice, and hyperbilirubinemia. The use of this technique prevents the development of hepatic cysts and ...

journal_title：Scandinavian journal of gastroenterology

authors： Aller MA,Lorente L,Alonso S,Arias J

更新日期：1993-01-01 00:00:00

abstract：:Eighty-one patients with diarrhoea due to suspected bacterial contamination of the small intestine were investigated with the bile acid breath test (BABT) and 75Se-labelled homocholic-tauro acid (SeHCAT). The impact of bile acid malabsorption due to dysfunction of the terminal ileum on BABT was evaluated. The group of...

journal_title：Scandinavian journal of gastroenterology

authors： Suhr O,Danielsson A,Hörstedt P,Stenling R

更新日期：1990-08-01 00:00:00

abstract：:Rabbit colonic biopsy specimens cultured in vitro showed an optimal release of prostaglandin E2 (PGE2) after 6-7 h of incubation. The amplitude but not the PGE2 production profile was dependent on stimuli applied--that is, A23187 greater than phorbol 12-myristate 13-acetate greater than control. This study was underta...

journal_title：Scandinavian journal of gastroenterology

authors： Nygård G,Berglindh T

更新日期：1991-02-01 00:00:00

abstract：:NSAIDs are widely used and beneficial for patients with inflammatory pain. However, NSAIDs cause significant adverse upper gastrointestinal effects, including increased mortality from serious ulcer complications. NSAIDs exert their anti-inflammatory effects by inhibiting the activity of the COX enzyme, which was recen...

journal_title：Scandinavian journal of gastroenterology

authors： Giercksky KE,Haglund U,Rask-Madsen J

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:Primary sclerosing cholangitis (PSC) confers a high risk of development of hepatobiliary carcinoma (HBC). The aim of the study was to identify indicators and risk factors for developing HBC in PSC patients. MATERIAL AND METHODS:Thirty-nine PSC patients with HBC at time of HBC diagnosis were compared with 101...

journal_title：Scandinavian journal of gastroenterology

authors： Tischendorf JJ,Meier PN,Strassburg CP,Klempnauer J,Hecker H,Manns MP,Krüger M

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Inducible NO synthase expression is upregulated in H. pylori-infected gastric mucosa, suggesting increased NO synthesis as part of a host defense reaction. This study investigates actual NO production in the human antrum in situ. METHODS:Gastroscopy with antral biopsy sampling and intragastric tonometric NO...

journal_title：Scandinavian journal of gastroenterology

authors： von Bothmer C,Edebo A,Lönroth H,Olbe L,Pettersson A,Fändriks L

更新日期：2002-04-01 00:00:00

abstract：:Secondary protectomy caused only one death in 59 patients while 10 deaths in the other 84 patients could be ascribed to simultaneous procedures such as colectomy. The perineal would was closed round a drainage tube. Healing was unrelated to age, primary or later protectomy, and corticosteroid medication. Mean healing ...

journal_title：Scandinavian journal of gastroenterology

authors： Grüner OP,Naas R,Flatmark A,Fretheim B,Gjone E

更新日期：1977-01-01 00:00:00

abstract：:Previous studies have shown that the small-bowel shunt operation for morbid obesity may be followed by signs of enhanced cell-mediated immunity and polymorphonuclear (PMN) granulocyte bactericidal capacity. In the present study seven patients, operated 4 months--4.5 years previously and exhibiting postoperative arthra...

journal_title：Scandinavian journal of gastroenterology

authors： Palmblad J,Engstedt L,Hallberg D,Norberg R,Udén AM

更新日期：1980-01-01 00:00:00

abstract：:In a study comprising 100 patients referred to a surgical clinic with symptoms suggestive of gastro-oesophageal reflux disease the value of different diagnostic procedures was investigated. Positive acid perfusion and 24-h pH tests were the commonest findings. Forty-nine per cent showed a normal oesophageal mucosa or ...

journal_title：Scandinavian journal of gastroenterology

authors： Johansson KE,Ask P,Boeryd B,Fransson SG,Tibbling L

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:Lactic acid bacteria have been reported to have antimutagenic and anticarcinogenic properties in vivo and in vitro. Lactobacillus acidophilus and Bifidobacterium longum have earlier been shown to bind the food mutagen Trp-P-2 in vitro. METHODS:The influence of oral supplementation with L. acidophilus NCFB 1...

journal_title：Scandinavian journal of gastroenterology

authors： Orrhage KM,Annas A,Nord CE,Brittebo EB,Rafter JJ

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Activin A, the homodimer of the activin/inhibin betaA subunit, has been shown to participate in cutaneous wound healing. In this study we intended to determine its part in gastric ulceration. METHODS:Activin A expression was studied by immunohistochemistry and in situ hybridization in acetic-acid-induced ch...

journal_title：Scandinavian journal of gastroenterology

authors： Becker JC,Hertel M,Markmann A,Shahin M,Werner S,Domschke W,Pohle T

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Visceral hyperalgesia is most likely a phenomenon of substantial clinical importance and may also play a role in the pathophysiology of the irritable bowel syndrome (IBS). We investigated the manifestation of visceral hyperalgesia in IBS patients by nociceptive electric stimulation of the rectosigmoid juncti...

journal_title：Scandinavian journal of gastroenterology

authors： Rössel P,Drewes AM,Petersen P,Nielsen J,Arendt-Nielsen L

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:Diagnosing early-stage acute autoimmune hepatitis (AIH) without pathological findings is difficult. Recent reports indicated that macrophages are not activated during disease development, unlike in other acute liver injuries. We suggest that hepatitis without macrophage activation should lack sinusoidal fibri...

journal_title：Scandinavian journal of gastroenterology

authors： Suzuki H,Harada S,Takao S,Takahashi M,Kato M,Kotoh K

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND/AIMS:The nonalcoholic fatty liver disease (NAFLD) activity score (NAS) is a newly proposed system to grade the necroinflammatory activity in liver biopsies of NAFLD patients. This study evaluates the usefulness of the NAS in predicting clinical deterioration and fibrosis progression in NAFLD. METHODS:One hu...

journal_title：Scandinavian journal of gastroenterology

authors： Ekstedt M,Franzén LE,Mathiesen UL,Kechagias S

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Postoperative bacterial infectious complications are frequent in patients with colorectal cancer (CRC), with subsequent increased recurrence rates and poor prognosis. Deficiency of the mannan-binding lectin (MBL) complement activation pathway may cause increased risk of infection in certain patient groups. I...

journal_title：Scandinavian journal of gastroenterology

authors： Ytting H,Jensenius JC,Christensen IJ,Thiel S,Nielsen HJ

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVES:Cytomegalovirus (CMV) often reactivates in ulcerative colitis (UC). In diagnostics, along with immunohistochemistry (IHC) of colonic biopsies, blood CMV polymerase chain reaction (PCR) is gaining increasing application. We aimed to assess agreement between the density of infected colonic cells by IHC and the...

journal_title：Scandinavian journal of gastroenterology

authors： Zagórowicz E,Przybysz A,Szlak J,Magdziak A,Wieszczy P,Mróz A

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Coumarin anticoagulants are known to cause hepatotoxicity, but only a few cases have been reported. Coumarins are usually administered following cardiovascular surgery and the differential diagnosis is post-transfusion hepatitis. METHODS:We report the case of a 46-year-old woman who presented with jaundice,...

journal_title：Scandinavian journal of gastroenterology

authors： Hinrichsen H,Lüttges J,Klöppel G,Fölsch UR,Schmidt WE

更新日期：2001-07-01 00:00:00

abstract：:To study the effects of chronic alcohol consumption on platelet functions, the rate of arachidonate-induced platelet aggregation, the production of malondialdehyde in platelets, and plasma levels of prostaglandin endoperoxide metabolites were examined in 88 chronic alcoholics and 24 healthy controls. The rate of plate...

journal_title：Scandinavian journal of gastroenterology

authors： Arai M,Okuno F,Nagata S,Shigeta Y,Takagi S,Ebihara Y,Kobayashi T,Ishii H,Tsuchiya M

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Previous studies suggest that E2 prostaglandins and the microflora may participate in the regulation of endocrine cells and of gastrointestinal cell kinetics. Our aim is to examine the actions of endogenous prostaglandins and of the microflora on gastrointestinal cell proliferation and tissue levels of neuro...

journal_title：Scandinavian journal of gastroenterology

authors： Uribe A,Alam M,Midtvedt T,Smedfors B,Theodorsson E

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:The functional role of the intracellular diacylglycerol/protein kinase C second-messenger pathway in the regulation of gastric acid secretion and the effects on the involved inositotrisphosphate/Ca2+/calmodulin system are not well understood, and contradictory data have been reported. We therefore evaluated ...

journal_title：Scandinavian journal of gastroenterology

authors： Kopp R,Pfeiffer A

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Dipeptidyl peptidase IV (DP IV, CD26), a serine protease with broad tissue distribution and known activity in serum, participates in T cell activation and promotes a Th1 cytokine response, a function in part attributable to its enzymatic activity. We hypothesized that the activity of DP IV in serum and expre...

journal_title：Scandinavian journal of gastroenterology

authors： Hildebrandt M,Rose M,Rüter J,Salama A,Mönnikes H,Klapp BF

更新日期：2001-10-01 00:00:00

abstract：:Rectal mucosal biopsies of 13 patients suffering from ulcerative colitis, 7 patients presenting symptomatology typical of irritable colon, and 7 control persons were studied by the recently introduced glyoxylic-acid-induced fluorescence histochemical method. In ulcerative colitis, compared to control specimens: 1) the...

journal_title：Scandinavian journal of gastroenterology

authors： Kyösola K,Penttilä O,Salaspuro M

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:The expression of two Helicobacter pylori proteins, CagA and VacA, is associated with more severe pathogenesis and clinical outcomes of the infection. However, this association varies among geographical regions and ethnic groups. We therefore evaluated CagA and VacA seroprevalence in H. pylori-positive dyspe...

journal_title：Scandinavian journal of gastroenterology

authors： Sokic-Milutinovic A,Wex T,Todorovic V,Milosavljevic T,Malfertheiner P

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Over the last few decades numerous regional and national registers have been established all over the world with the aim of improving survival in familial adenomatous polyposis (FAP). The Danish Polyposis Register was founded in 1971 and coordinates the screening and subsequent prophylactic colectomy of FAP ...

journal_title：Scandinavian journal of gastroenterology

authors： Bülow S,Bülow C,Nielsen TF,Karlsen L,Moesgaard F

更新日期：1995-10-01 00:00:00

abstract：:This study describes the clinical features and management of 80 patients with Crohn's disease affecting initially only the rectum with or without involvement of the sigmoid colon. Most patients were treated medically, and the various measures used are considered; the cumulative probability of completing five years und...

journal_title：Scandinavian journal of gastroenterology

authors： Ritchie JK,Lennard-Jones JE

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Primary adenocarcinoma of the duodenum is an uncommon clinical entity. It has been associated with a dismal prognosis because it is rare and produces no distinctive symptoms until late in its course. CASE SUMMARY:A 68-year-old man presented with a 6-month history of epigastralgia, anorexia, and progressive ...

journal_title：Scandinavian journal of gastroenterology

authors： Tsai CJ

更新日期：1994-10-01 00:00:00

abstract：:The metabolism of cyclic AMP and HCl secretion has been studied in eight healthy volunteers, in eight duodenal ulcer (DU) patients, and in four pernicious anaemia patients. Pentagastrin showed a tendency to increase adenylate cyclase and cyclic nucleotide phosphodiesterase activities in the fundal mucosa and caused a ...

journal_title：Scandinavian journal of gastroenterology

authors： Varis K,Raij K,Härkönen M,Miettinen TA

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Atrophic gastritis, a risk factor for gastric cancer, is a late consequence of Helicobacter pylori infection in approximately one-third of the infected patients. It has been suggested that gastric cancer would develop less frequently if H. pylori were eradicated. However, the prevalence of H. pylori infectio...

journal_title：Scandinavian journal of gastroenterology

authors： Kokkola A,Rautelin H,Puolakkainen P,Sipponen P,Färkkilä M,Haapiainen R,Kosunen TU

更新日期：2000-02-01 00:00:00