Main glucosidase conversion products of the gluco-alkaloids dolichantoside and palicoside.

Abstract:

:The enzymatic glucose cleavage of palicoside revealed the biosynthetic pathway to akagerine, whereas the conversion of dolichantoside led to a new quaternary heteroyohimbine alkaloid named N(b)-methyl-21-beta-hydroxy-mayumbine. The hypothetical models of reactions occurring after the conversion of both substrates are proposed. Dolichantoside and palicoside, as well as Strychnos mellodora stem bark crude ethanol extract, exhibit significant antimycotic activity against human pathogens in presence of specific glucosidase.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Brandt V,Tits M,Penelle J,Frédérich M,Angenot L

doi

10.1016/s0031-9422(01)00085-1

subject

Has Abstract

pub_date

2001-07-01 00:00:00

pages

653-9

issue

5

eissn

0031-9422

issn

1873-3700

pii

S0031-9422(01)00085-1

journal_volume

57

pub_type

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