Abstract:
:Three C-17 diacetylenic compounds (1-3), one monoterpenoid (4), seven ceramides (leucoceramides A-G, 5a-g), six cerebrosides (leucocerebrosides A-F, 6a-f) and nine known compounds were isolated from the methanolic extract of Hydrocotyle leucocephala. Their structures were established by spectroscopic methods. The isolated compounds 1-3, 5a-g, 6a-f and 7 were shown to be active in the lipopolysaccharide (LPS) induced cytokine production assay for IL-10, IL-12, and TNF-alpha.
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Ramos F,Takaishi Y,Kawazoe K,Osorio C,Duque C,Acuña R,Fujimoto Y,Sato M,Okamoto M,Oshikawa T,Ahmed SUdoi
10.1016/j.phytochem.2006.03.004subject
Has Abstractpub_date
2006-06-01 00:00:00pages
1143-50issue
11eissn
0031-9422issn
1873-3700pii
S0031-9422(06)00149-Xjournal_volume
67pub_type
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