Abstract:
:The authors report three patients with acute, chronic, and recurrent neuropathy associated with varicella zoster virus (VZV) infection but without zoster rash. CSF of all three patients contained VZV immunoglobulin G antibody, but not herpes simplex virus. In two patients, serum/CSF ratios of VZV immunoglobulin G were reduced compared to normal ratios for immunoglobulin G and albumin, and one patient also had VZV immunoglobulin M in CSF. All three patients received antiviral therapy and improved. The diagnosis of nervous system infection by VZV may be confirmed by the presence of antibody to VZV in CSF even without detectable VZV DNA.
journal_name
Neurologyjournal_title
Neurologyauthors
Fox RJ,Galetta SL,Mahalingam R,Wellish M,Forghani B,Gilden DHdoi
10.1212/wnl.57.2.351subject
Has Abstractpub_date
2001-07-24 00:00:00pages
351-4issue
2eissn
0028-3878issn
1526-632Xjournal_volume
57pub_type
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