Acute, chronic, and recurrent varicella zoster virus neuropathy without zoster rash.

Abstract:

:The authors report three patients with acute, chronic, and recurrent neuropathy associated with varicella zoster virus (VZV) infection but without zoster rash. CSF of all three patients contained VZV immunoglobulin G antibody, but not herpes simplex virus. In two patients, serum/CSF ratios of VZV immunoglobulin G were reduced compared to normal ratios for immunoglobulin G and albumin, and one patient also had VZV immunoglobulin M in CSF. All three patients received antiviral therapy and improved. The diagnosis of nervous system infection by VZV may be confirmed by the presence of antibody to VZV in CSF even without detectable VZV DNA.

journal_name

Neurology

journal_title

Neurology

authors

Fox RJ,Galetta SL,Mahalingam R,Wellish M,Forghani B,Gilden DH

doi

10.1212/wnl.57.2.351

subject

Has Abstract

pub_date

2001-07-24 00:00:00

pages

351-4

issue

2

eissn

0028-3878

issn

1526-632X

journal_volume

57

pub_type

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