Immune reconstitution inflammatory syndrome associated with PML in AIDS: a treatable disorder.

Abstract:

:An HIV-1-infected patient with progressive multifocal leukoencephalopathy presented clinical deterioration and contrast-enhancing lesions on brain nuclear MR after the initiation of highly active antiretroviral therapy (HAART). Brain biopsy identified an inflammatory reaction compatible with immune reconstitution inflammatory syndrome. Treatment with corticosteroids and transient suppression of HAART led to marked neurologic improvement.

journal_name

Neurology

journal_title

Neurology

authors

Martinez JV,Mazziotti JV,Efron ED,Bonardo P,Jordan R,Sevlever G,Martinez M,Verbanaz SC,Salazar ZS,Pardal MF,Reisin R

doi

10.1212/01.wnl.0000242728.26433.12

subject

Has Abstract

pub_date

2006-11-14 00:00:00

pages

1692-4

issue

9

eissn

0028-3878

issn

1526-632X

pii

67/9/1692

journal_volume

67

pub_type

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