Abstract:
:A 17-month-old boy developed herpes zoster ophthalmicus (HZO) and delayed contralateral hemiparesis following intrauterine varicella exposure. CT demonstrated multiple areas of hypodensity in the left basal ganglia, and angiography showed occlusion of left lenticulostriate arteries. As in most adults with HZO and delayed hemiparesis, this infant had a self-limiting course with excellent recovery.
journal_name
Neurologyjournal_title
Neurologyauthors
Leis AA,Butler IJdoi
10.1212/wnl.37.9.1537subject
Has Abstractpub_date
1987-09-01 00:00:00pages
1537-8issue
9eissn
0028-3878issn
1526-632Xjournal_volume
37pub_type
杂志文章相关文献
NEUROLOGY文献大全abstract::To determine if there is abnormal phenylalanine and biopterin metabolism in patients with dopa-responsive dystonia (DRD), we measured plasma levels of phenylalanine, tyrosine, biopterin, and neopterin at baseline, and 1, 2, 4, and 6 hours after an oral phenylalanine load (100 mg/kg). Seven adults with DRD, two severel...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.48.5.1290
更新日期:1997-05-01 00:00:00
abstract::We studied imagery for learned, skilled movements (praxis imagery) in a patient with severe ideomotor apraxia and intact language abilities. This patient, who made predominantly spatial and movement errors when performing transitive movements demonstrating the use of tools (transitive gestures), was also impaired in h...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.49.2.474
更新日期:1997-08-01 00:00:00
abstract:OBJECTIVE:To determine whether changes in brain biometals in Alzheimer disease (AD) and in normal brain tissue are tandemly associated with amyloid beta-peptide (Abeta) burden and dementia severity. METHODS:The authors measured zinc, copper, iron, manganese, and aluminum and Abeta levels in postmortem neocortical tiss...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000223644.08653.b5
更新日期:2006-07-11 00:00:00
abstract:OBJECTIVE:To assess the natural progression of muscle weakness in spinal muscular atrophy (SMA) IIIb. METHODS:Ten patients with SMA IIIb were followed for at least 10 years. Age at disease onset varied between 9 and 18 years. Patients were initially seen 2 to 10 years after disease onset. They were evaluated at approx...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000324623.89105.c4
更新日期:2008-08-26 00:00:00
abstract:OBJECTIVE:To investigate the safety and efficacy of escalating doses of the semi-synthetic triterpenoid omaveloxolone in patients with mitochondrial myopathy. METHODS:In cohorts of 8-13, 53 participants were randomized double-blind to 12 weeks of treatment with omaveloxolone 5, 10, 20, 40, 80, or 160 mg, or placebo. O...
journal_title:Neurology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1212/WNL.0000000000008861
更新日期:2020-02-18 00:00:00
abstract::Four of five members of a family complained of repeated attacks of hemiplegic migraine, migraine with aura of different types, or migraine without aura. The hemiplegia always outlasted the headache and was often accompanied by altered consciousness, aphasia, and, in one patient, coma; in this latter patient, the ictal...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.45.1.33
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Posterior cortical atrophy (PCA) is a progressive dementia characterized by prominent disorders of higher visual processing, affecting both dorsal and ventral streams to cause Balint's syndrome, alexia, and visual agnosia. OBJECTIVE:To define the cognitive profile of PCA and compare to the typical, primary ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000196477.78548.db
更新日期:2006-02-14 00:00:00
abstract::Although the long-term effects of acute anoxia have been studied, the effects of chronic hypoxia on the developing human brain have received little attention. We studied children with a cyanotic congenital heart defect to assess the impact of chronic hypoxia by eight measures: neurologic examination, visual evoked res...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.35.1.42
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVE:To assess the available evidence for the diagnostic accuracy of CSF testing for protein 14-3-3 in patients with suspected sporadic Creutzfeldt-Jakob disease (sCJD). METHODS:The authors performed a systematic review of the available literature from 1995 to January 1, 2011, to identify articles involving patie...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31826d5fc3
更新日期:2012-10-02 00:00:00
abstract:OBJECTIVE:To assess the association of early morning serum cortisol with cognitive performance and brain structural integrity in community-dwelling young and middle-aged adults without dementia. METHODS:We evaluated dementia-free Framingham Heart Study (generation 3) participants (mean age 48.5 years, 46.8% men) who u...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000006549
更新日期:2018-11-20 00:00:00
abstract:OBJECTIVE:To investigate whether neuronal activity-regulated pentraxin (Narp) colocalizes with hypocretin (Hcrt or orexin) in the normal human brain and to determine if Narp staining is lost in the narcoleptic human brain. BACKGROUND:Human narcolepsy is characterized by a loss of the peptide hypocretin in the hypothal...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000175219.01544.c8
更新日期:2005-10-25 00:00:00
abstract:OBJECTIVE:To investigate evidence of the potential role of early cortical vulnerability in the development of primary progressive aphasia (PPA). METHOD:A woman with a diagnosis of PPA and her 9 adult siblings, 7 with developmental language disabilities, underwent neuropsychological testing, structural MRI, and resting...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000009842
更新日期:2020-08-18 00:00:00
abstract:OBJECTIVE:This study aims to evaluate protective effects of brief repetitive bilateral arm ischemic preconditioning (BAIPC) on stroke recurrence in patients with symptomatic atherosclerotic intracranial arterial stenosis (IAS). METHODS:A total of 68 consecutive cases with symptomatic IAS, diagnosed by imaging, were en...
journal_title:Neurology
pub_type: 杂志文章,随机对照试验
doi:10.1212/WNL.0b013e318271f76a
更新日期:2012-10-30 00:00:00
abstract:BACKGROUND:In children with tuberous sclerosis, the PET tracer alpha[11C]methyl-L-tryptophan (AMT) has been shown to be selectively taken up by epileptogenic tubers, thus allowing differentiation from nonepileptogenic tubers in the interictal state. OBJECTIVE:To determine whether cortical areas showing increased AMT u...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000049468.05050.f2
更新日期:2003-03-25 00:00:00
abstract:OBJECTIVES:Deep brain stimulation of the internal pallidum (GPi-DBS) is an established therapeutic option in treatment-refractory dystonia, and the identification of factors predicting surgical outcome is needed to optimize patient selection. METHODS:In this retrospective multicenter study, GPi-DBS outcome of 8 patien...
journal_title:Neurology
pub_type: 杂志文章,多中心研究
doi:10.1212/WNL.0000000000001312
更新日期:2015-03-03 00:00:00
abstract:OBJECTIVE:To determine whether 24 weeks of high-intensity progressive aerobic exercise (PAE) affects brain MRI measures in people with multiple sclerosis (MS). METHODS:We conducted a randomized, controlled, phase 2 trial (with a crossover follow-up) including an exercise group (supervised PAE followed by self-guided p...
journal_title:Neurology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1212/WNL.0000000000011241
更新日期:2021-01-12 00:00:00
abstract:OBJECTIVE:The aim of this study was to clarify myocardial involvement and its clinical implications in subjects with spinal and bulbar muscular atrophy (SBMA), a neuromuscular disease affecting both neuronal and nonneuronal tissues. METHODS:Two independent cardiologists evaluated ECGs from a total of 144 consecutive s...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000000434
更新日期:2014-05-20 00:00:00
abstract:BACKGROUND:Because of the relatively poor results of frontal lobe epilepsy (FLE) surgery, identification of prognostic factors for surgical outcome is of great importance. METHODS:To identify predictive factors for FLE surgery, we analyzed the data of 61 patients (mean age at surgery 19.2) who had undergone presurgica...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/wnl.54.7.1470
更新日期:2000-04-11 00:00:00
abstract::Mapping eloquent language cortex in presurgical patients typically is accomplished using highly invasive direct cortical stimulation techniques. Functional imaging during language activation using positron emission tomography (PET) is a promising, noninvasive alternative that requires validation. In seven patients und...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.48.4.1056
更新日期:1997-04-01 00:00:00
abstract::A patient presented with bilateral brachial plexus neuropathy which 2 weeks later evolved into a polyneuropathy involving all four extremities. On further investigation, the patient was found to have systemic lupus erythematosus. Treatment with steroids was accompanied by complete resolution of the neurologic findings...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.29.12.1633-a
更新日期:1979-12-01 00:00:00
abstract::We performed serial baseline and gadolinium (Gd)-DTPA-enhanced MRI in 4 patients with definite multiple sclerosis. Studies were performed every month for a total of 4 scans. We obtained short TR/short TE sequences at 10 and 60 minutes after Gd-DTPA injection. All patients had multiple hyperintense lesions seen on base...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.40.4.591
更新日期:1990-04-01 00:00:00
abstract:OBJECTIVE:To characterize a brainstem location specific to coma-causing lesions, and its functional connectivity network. METHODS:We compared 12 coma-causing brainstem lesions to 24 control brainstem lesions using voxel-based lesion-symptom mapping in a case-control design to identify a site significantly associated w...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000003404
更新日期:2016-12-06 00:00:00
abstract::The scanning electronmicroscope was used to study the development of anencephaly in an experimental model. Anencephaly was produced consistently, using vitamin A as the teratogen. Embryos destined to become anencephalic displayed failure of opposing sides of the rostral neural tube to fuse. Subsequently, the neural fo...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.32.9.992
更新日期:1982-09-01 00:00:00
abstract::Studies of automobile accident frequency among drivers with AD have yielded conflicting results about the risk of accidents. To develop a practice parameter regarding driving and AD the authors performed a systematic review of the literature. The authors identified well-designed, controlled studies of driving and AD u...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/wnl.54.12.2205
更新日期:2000-06-27 00:00:00
abstract:OBJECTIVE:Glatiramer acetate (formerly known as copolymer 1) is the major noninterferon immunomodulatory agent used in the treatment of relapsing-remitting multiple sclerosis. Its mechanism of action over the past 40 years has evolved with our understanding of the immune response. METHODS:We review the various mechani...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/WNL.0b013e3181c97e39
更新日期:2010-01-05 00:00:00
abstract::Phenotypic heterogeneity of sporadic Creutzfeldt-Jakob disease (CJD) has been linked to biochemically distinct types of the protease-resistant form of the prion protein (type 1 and type 2 PrP(Sc)). We investigated 14 cases of sporadic CJD and found that both type 1 and type 2 PrP(Sc) coexisted in 5 subjects. The disti...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.53.9.2173
更新日期:1999-12-10 00:00:00
abstract::This is a case study of a patient with the clinical diagnosis of meningoencephalitis. It demonstrates the in vivo development of plasma cells in the central nervous system. All the stages of in vitro mitogen-induced lymphocyte transformation previously described by light and electron microscopy are recapitulated in th...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.27.5.448
更新日期:1977-05-01 00:00:00
abstract::Since the emergence of the specialty, neurologists have worked with a rather restricted list of relatively inexpensive pharmacologic agents. This is rapidly changing with the development of new agents for the treatment of migraine, multiple sclerosis, Parkinson's disease, Alzheimer's disease, and epilepsy, accelerated...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.45.3.569
更新日期:1995-03-01 00:00:00
abstract:OBJECTIVE:The state-of-the-art tools of neurology, in particular modern neuroimaging techniques, have yet to benefit from the revolution in mobile technologies that provide new insights into the mechanisms underlying clinical syndromes. This study demonstrates the manner in which mobile technologies may provide informa...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31824528b2
更新日期:2012-01-31 00:00:00
abstract:OBJECTIVE:To assess the frequency of this finding in patients with minor stroke and TIAs compared to those with stroke mimics and to evaluate the level of agreement between examiners to detect an upgoing thumb sign. METHODS:We previously reported an upgoing thumb sign as a subtle clinical finding in patients with tran...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000004157
更新日期:2017-07-25 00:00:00