Evidence-based guideline: diagnostic accuracy of CSF 14-3-3 protein in sporadic Creutzfeldt-Jakob disease: report of the guideline development subcommittee of the American Academy of Neurology.

abstract：OBJECTIVES:To provide information on the effect of the coronavirus disease of 2019 (COVID-19) pandemic on people with epilepsy and provide consensus recommendations on how to provide the best possible care for people with epilepsy while avoiding visits to urgent care facilities and hospitalizations during the novel cor...

journal_title：Neurology

authors： French JA,Brodie MJ,Caraballo R,Devinsky O,Ding D,Jehi L,Jette N,Kanner A,Modi AC,Newton CR,Patel AA,Pennell PB,Perucca E,Sander JW,Scheffer IE,Singh G,Williams E,Wilmshurst J,Cross JH

更新日期：2020-06-09 00:00:00

abstract：:We previously described demyelination in the brain and subacute combined degeneration of the spinal cord in a patient with 5,10-methylenetetrahydrofolate reductase deficiency. To assess the role of methionine, S-adenosylmethionine, folate, and neurotransmitter amine metabolism in the demyelination process, we measured...

journal_title：Neurology

authors： Hyland K,Smith I,Bottiglieri T,Perry J,Wendel U,Clayton PT,Leonard JV

更新日期：1988-03-01 00:00:00

abstract：:In spinal cords from seven amyotrophic lateral sclerosis (ALS) patients and four controls, we found no difference in thyrotropin-releasing hormone (TRH) concentration relative to protein content, but there was a reduction per tissue wet weight in ALS. Immunohistochemical localization of TRH in ALS cord was unaltered. ...

journal_title：Neurology

authors： Jackson IM,Adelman LS,Munsat TL,Forte S,Lechan RM

更新日期：1986-09-01 00:00:00

abstract：OBJECTIVE:To determine whether vascular and neurodegenerative factors influence cognition before clinically relevant Alzheimer disease pathology, we analyzed MRI measures and amyloid imaging in an ethnoracially diverse cohort of cognitively normal individuals older than 60 years. METHODS:Participants (n = 154; mean ag...

journal_title：Neurology

authors： Han JW,Maillard P,Harvey D,Fletcher E,Martinez O,Johnson DK,Olichney JM,Farias ST,Villeneuve S,Jagust W,Mungas D,DeCarli C

更新日期：2020-11-10 00:00:00

abstract：OBJECTIVE:To measure white matter (WM) and gray matter (GM) atrophy and lesion load in a large population of patients with multiple sclerosis (MS) using a fully automated, operator-independent, multiparametric segmentation method. METHODS:The study population consisted of 597 patients with MS and 104 control subjects....

journal_title：Neurology

authors： Tedeschi G,Lavorgna L,Russo P,Prinster A,Dinacci D,Savettieri G,Quattrone A,Livrea P,Messina C,Reggio A,Bresciamorra V,Orefice G,Paciello M,Brunetti A,Coniglio G,Bonavita S,Di Costanzo A,Bellacosa A,Valentino P,Quar

更新日期：2005-07-26 00:00:00

abstract：BACKGROUND:Several studies indicate semantic fluency more sensitively discriminates patients with Alzheimer disease (AD) from normal elderly persons, with disproportionate impairment of semantic over phonemic fluency. OBJECTIVE:To determine the ability of abbreviated fluency measures in the clinic setting (1-minute le...

journal_title：Neurology

authors： Canning SJ,Leach L,Stuss D,Ngo L,Black SE

更新日期：2004-02-24 00:00:00

abstract：OBJECTIVE:To determine the prevalence of AD and other dementias in a rural elderly Hindi-speaking population in Ballabgarh in northern India. DESIGN:The authors performed a community survey of a cohort of 5,126 individuals aged 55 years and older, 73.3% of whom were illiterate. Hindi cognitive and functional screening...

journal_title：Neurology

authors： Chandra V,Ganguli M,Pandav R,Johnston J,Belle S,DeKosky ST

更新日期：1998-10-01 00:00:00

abstract：:A 66-year-old woman with acute idiopathic polyneuritis (Landry-Guillain-Barré [LGB] syndrome) had normal extraocular movements, but her pupils did not react to light or accommodation. This is the first such case to be reported. Pharmacologic testing pointed to postganglionic involvement of parasympathetic and sympathe...

journal_title：Neurology

authors： Williams D,Brust JC,Abrams G,Challenor Y,Devereaux M

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:The clinical characteristics of Tourette syndrome (TS) present challenges for the systematic determination of whether individuals are affected and severity. Vocal and motor tics wax and wane, decrease over time, and may be voluntarily suppressible, and therefore may be absent at interview. Current instrument...

journal_title：Neurology

authors： Robertson MM,Banerjee S,Kurlan R,Cohen DJ,Leckman JF,McMahon W,Pauls DL,Sandor P,van de Wetering BJ

更新日期：1999-12-10 00:00:00

abstract：BACKGROUND:Ullrich congenital muscular dystrophy (UCMD) is a form of merosin-positive congenital muscular dystrophy characterized by proximal contractures, distal laxity, rigidity of the spine, and respiratory complications. Recently, a deficiency of collagen VI on muscle and skin biopsy together with recessive mutatio...

journal_title：Neurology

authors： Mercuri E,Yuva Y,Brown SC,Brockington M,Kinali M,Jungbluth H,Feng L,Sewry CA,Muntoni F

更新日期：2002-05-14 00:00:00

abstract：OBJECTIVE:To evaluate the effect of amyloid imaging on clinical decision making. METHODS:We conducted a retrospective analysis of 140 cognitively impaired patients (mean age 65.0 years, 46% primary β-amyloid (Aβ) diagnosis, mean Mini-Mental State Examination 22.3) who underwent amyloid (Pittsburgh compound B [PiB]) PE...

journal_title：Neurology

authors： Sánchez-Juan P,Ghosh PM,Hagen J,Gesierich B,Henry M,Grinberg LT,O'Neil JP,Janabi M,Huang EJ,Trojanowski JQ,Vinters HV,Gorno-Tempini M,Seeley WW,Boxer AL,Rosen HJ,Kramer JH,Miller BL,Jagust WJ,Rabinovici GD

更新日期：2014-01-21 00:00:00

abstract：:This manuscript provides a practical summary of guidelines for institution of apomorphine subcutaneous injectable therapy, including patient education, pre-treatment issues, dosage titration and side-effect care. The timing of each injection is crucial if an impending "off" period is to be averted. Patients need to be...

journal_title：Neurology

authors： Bowron A

更新日期：2004-03-23 00:00:00

abstract：OBJECTIVE:We sought cognitive event-related potential (ERP) biomarkers of disease progression and subsequent conversion to dementia in mild cognitive impairment (MCI). BACKGROUND:Two ERP components, the P600 and N400, are sensitive to abnormal episodic/declarative memory and semantic processing. When congruous categor...

journal_title：Neurology

authors： Olichney JM,Taylor JR,Gatherwright J,Salmon DP,Bressler AJ,Kutas M,Iragui-Madoz VJ

更新日期：2008-05-06 00:00:00

abstract：OBJECTIVE:To study the impact of negative expectation related to receiving a placebo (the "lessebo effect") on efficacy outcome measures of symptomatic treatments in Parkinson disease (PD). METHODS:We conducted meta-analyses of double-blind randomized controlled trials (RCTs) of dopamine agonists in PD and compared th...

journal_title：Neurology

authors： Mestre TA,Shah P,Marras C,Tomlinson G,Lang AE

更新日期：2014-04-22 00:00:00

abstract：:To study the anti-Schwann cell activity of serum from patients with Guillain-Barré syndrome (GBS), we used a 51Cr-release cytotoxicity assay. Specific release of 51Cr mediated by GBS serum did not differ from that with normals or disease controls. Heating sera from GBS patients or controls at 56 or 50 degrees C for 30...

journal_title：Neurology

authors： Lisak RP,Kuchmy D,Armati-Gulson PJ,Brown MJ,Sumner AJ

更新日期：1984-09-01 00:00:00

abstract：:We present a patient with levodopa-resistant parkinsonism due to basal ganglia calcification related to surgically-induced hypoparathyroidism. The calcification was seen on computerized axial tomography but not on skull x-rays. Such calcification should be looked for in all cases of levodopa-resistant parkinsonism, si...

journal_title：Neurology

authors： Klawans HL,Lupton M,Simon L

更新日期：1976-03-01 00:00:00

abstract：:Charcot-Marie-Tooth disease type 1 (CMT1) is associated with atrophy and degeneration of peripheral nerve axons in addition to prominent changes in the structure of Schwann cells. We have investigated the composition of the axonal cytoskeleton in sural nerve biopsies from patients with CMT1. Compared to controls, CMT1...

journal_title：Neurology

authors： Watson DF,Nachtman FN,Kuncl RW,Griffin JW

更新日期：1994-12-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection may be associated with neurocognitive deficits. The Hemophilia Growth and Development Study enrolled HIV-infected and HIV-uninfected patients and a group of nonhemophiliac siblings. After controlling for multiple factors, HCV monoinfection was not associated with deficits in adaptive ...

journal_title：Neurology

authors： Soogoor M,Lynn HS,Donfield SM,Gomperts E,Bell TS,Daar ES,Hemophilia Growth and Development Study.

更新日期：2006-10-24 00:00:00

abstract：OBJECTIVE:The purpose of this cross-sectional study was to determine the prevalence and potential significance of stroke symptoms among end-stage renal disease (ESRD) patients without a prior diagnosis of stroke or TIA. METHODS:We enrolled 148 participants with ESRD from 5 clinics. Stroke symptoms and functional statu...

journal_title：Neurology

authors： Kurella Tamura M,Meyer JB,Saxena AB,Huh JW,Wadley VG,Schiller B

更新日期：2012-09-04 00:00:00

abstract：OBJECTIVE:To explore the incidence of depression and anxiety and to measure quality of life in women with idiopathic intracranial hypertension (IIH), a matched group cross-sectional study was conducted. Women with IIH (n = 28) were compared with control groups of weight- and age-matched women not diagnosed with IIH (n ...

journal_title：Neurology

authors： Kleinschmidt JJ,Digre KB,Hanover R

更新日期：2000-01-25 00:00:00

abstract：OBJECTIVE:To investigate whether impaired spatial memory contributes to cognitive deficits in idiopathic cervical dystonia (ICD). METHODS:The authors tested 16 untreated patients with ICD and 16 healthy controls with four variants of a classic spatial memory task, in which subjects were requested to recall the locatio...

journal_title：Neurology

authors： Ploner CJ,Stenz U,Fassdorf K,Arnold G

更新日期：2005-05-24 00:00:00

abstract：OBJECTIVES:To evaluate the effect of intensive care unit continuous EEG (cEEG) monitoring on inpatient mortality, hospital charges, and length of stay. METHODS:A retrospective cross-sectional study was conducted using the Nationwide Inpatient Sample, a dataset representing 20% of inpatient discharges in nonfederal US ...

journal_title：Neurology

authors： Ney JP,van der Goes DN,Nuwer MR,Nelson L,Eccher MA

更新日期：2013-12-03 00:00:00

abstract：BACKGROUND:The major histocompatibility complex (MHC) has been consistently associated with susceptibility to MS and the course of several other human autoimmune diseases. A putative association between the course and severity of MS and the MHC remains controversial. METHODS:DR and DQ genotyping by either restriction ...

journal_title：Neurology

authors： Weinshenker BG,Santrach P,Bissonet AS,McDonnell SK,Schaid D,Moore SB,Rodriguez M

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:To demonstrate that progress has been made in unifying brain death determination guidelines in the last decade by directly comparing the policies of the US News and World Report's top 50 ranked neurologic institutions from 2006 and 2015. METHODS:We solicited official hospital guidelines in 2015 from these to...

journal_title：Neurology

authors： Wang HH,Varelas PN,Henderson GV,Wijdicks EF,Greer DM

更新日期：2017-02-07 00:00:00

abstract：OBJECTIVE:To investigate whether admission hyperglycemia predicts poststroke infections and, if so, whether poststroke infections modify the effect of admission hyperglycemia on functional outcome in ischemic stroke. METHODS:We used data from acute ischemic stroke patients in the Preventive Antibiotics in Stroke Study...

journal_title：Neurology

authors： Zonneveld TP,Nederkoorn PJ,Westendorp WF,Brouwer MC,van de Beek D,Kruyt ND,PASS Investigators.

更新日期：2017-04-11 00:00:00

abstract：:A veterinarian contracted rabies in the course of laboratory work with homogenates of rabid goat brain. Epidemiologic study determined a respiratory mode of transmission. After a fulminant encephalitic illness, formed rabies virions were identified in the synaptic zones of the olfactory glomeruli. Identification, isol...

journal_title：Neurology

authors： Conomy JP,Leibovitz A,McCombs W,Stinson J

更新日期：1977-01-01 00:00:00

abstract：:A national survey, based on a probability sample of patients admitted to short-term hospitals in the United States during 1973 to 1974 with a discharge diagnosis of an intracranial neoplasm, was conducted in 157 hospitals. The annual incidence was estimated at 17,000 for primary intracranial neoplasms and 17,400 for s...

journal_title：Neurology

authors： Walker AE,Robins M,Weinfeld FD

更新日期：1985-02-01 00:00:00

abstract：:Creatine monohydrate has been shown to increase strength in studies of young healthy subjects and in a few studies with patients. Creatine monohydrate (10 g daily for 5 days to 5 g daily for 5 days) was administered to patients with neuromuscular disease in a pilot study (Study 1; n = 81), followed by a single-blinded...

journal_title：Neurology

authors： Tarnopolsky M,Martin J

更新日期：1999-03-10 00:00:00

abstract：:We report a longitudinal follow-up study on six patients with chronic manganese-induced parkinsonism following cessation of manganese exposure. Compared with the 1987 study, their parkinsonian symptoms showed a slow progression, particularly in gait disturbances such as freezing during turning and walking backward wit...

journal_title：Neurology

authors： Huang CC,Lu CS,Chu NS,Hochberg F,Lilienfeld D,Olanow W,Calne DB

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:While neuropsychological deficits have been reported in healthy individuals who use street cannabis, data in patients with multiple sclerosis (MS) are lacking. Given that MS is associated with cognitive deterioration, the aim of this study was to determine the neuropsychological effects of cannabis use in th...

journal_title：Neurology

authors： Honarmand K,Tierney MC,O'Connor P,Feinstein A

更新日期：2011-03-29 00:00:00