Response to cancer therapy in a patient with a paraneoplastic choreiform disorder.

Abstract:

:The authors report a patient with chorea and multifocal neurologic abnormalities associated with a small-cell lung carcinoma. A previously unreported antibody directed at a 76-kD neuronal protein antigen was identified in both serum and CSF. Antitumor treatment resulted in dramatic and sustained clinical neurologic and serologic responses.

journal_name

Neurology

journal_title

Neurology

authors

Croteau D,Owainati A,Dalmau J,Rogers LR

doi

10.1212/wnl.57.4.719

subject

Has Abstract

pub_date

2001-08-28 00:00:00

pages

719-22

issue

4

eissn

0028-3878

issn

1526-632X

journal_volume

57

pub_type

杂志文章,评审
  • Clinical-pathologic study of depressive symptoms and cognitive decline in old age.

    abstract:OBJECTIVE:To clarify the relationship between depressive symptoms and the clinical and neuropathologic manifestations of dementia. METHODS:In a clinical-pathologic cohort study, 1,764 older persons without cognitive impairment at enrollment completed annual clinical evaluations for a mean of 7.8 years. The evaluations...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000000715

    authors: Wilson RS,Capuano AW,Boyle PA,Hoganson GM,Hizel LP,Shah RC,Nag S,Schneider JA,Arnold SE,Bennett DA

    更新日期:2014-08-19 00:00:00

  • Reemergence of activation with poststroke somatosensory recovery: a serial fMRI case study.

    abstract::The authors demonstrate the potential for poststroke return of activation in regions normally involved in touch discrimination in a serial, whole-brain fMRI study of a patient with marked sensory loss followed by good recovery. A return of activation in ipsilesional primary and bilateral secondary somatosensory cortic...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.59.5.749

    authors: Carey LM,Abbott DF,Puce A,Jackson GD,Syngeniotis A,Donnan GA

    更新日期:2002-09-10 00:00:00

  • Retinal pathology in idiopathic moyamoya angiopathy detected by optical coherence tomography.

    abstract:OBJECTIVE:To investigate whether patients with moyamoya angiopathy without obvious retinal pathologies such as retinal infarctions or the congenital morning glory anomaly may have subtle subclinical retinal changes. METHODS:In this cross-sectional study, spectral domain optical coherence tomography was used to analyze...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000001832

    authors: Albrecht P,Blasberg C,Lukas S,Ringelstein M,Müller AK,Harmel J,Kadas EM,Finis D,Guthoff R,Aktas O,Hartung HP,Paul F,Brandt AU,Berlit P,Methner A,Kraemer M

    更新日期:2015-08-11 00:00:00

  • West Nile virus infection presenting as acute flaccid paralysis in an HIV-infected patient: a case report and review of the literature.

    abstract::We describe a case of West Nile virus (WNV) infection in an HIV-infected patient who presented with an isolated flaccid monoparesis of the right upper extremity. To our knowledge, this is the first reported case of flaccid paralysis caused by WNV infection in an HIV-infected patient. We then review the medical literat...

    journal_title:Neurology

    pub_type: 杂志文章,评审

    doi:10.1212/01.wnl.0000253223.07720.bb

    authors: Torno M,Vollmer M,Beck CK

    更新日期:2007-02-13 00:00:00

  • Syphilitic meningomyelitis.

    abstract::A 28-year-old nonimmunocompromised man developed secondary syphilis confirmed by serum and CSF findings. His course was complicated by chorioretinitis, extensive skin lesions, and spastic paraparesis secondary to syphilitic meningomyelitis. MRI of the spinal cord was strikingly abnormal. ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.41.2_part_1.325

    authors: Strom T,Schneck SA

    更新日期:1991-02-01 00:00:00

  • Polymyositis: an overdiagnosed entity.

    abstract:BACKGROUND:According to widely used criteria (Bohan and Peter criteria, 1975), dermatomyositis (DM) is differentiated from polymyositis (PM) only by skin changes. More recent criteria also include histopathologic characteristics enabling the distinction between PM and DM and the differentiation of sporadic inclusion bo...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.61.3.316

    authors: van der Meulen MF,Bronner IM,Hoogendijk JE,Burger H,van Venrooij WJ,Voskuyl AE,Dinant HJ,Linssen WH,Wokke JH,de Visser M

    更新日期:2003-08-12 00:00:00

  • Primary cervical dystonia and scoliosis: a multicenter case-control study.

    abstract:OBJECTIVE:To study the distribution of prior scoliosis among patients with primary adult-onset cervical dystonia (CD) and matched control subjects. METHODS:Case and control subjects were selected among consecutive outpatients attending four Italian centers. Control outpatients were matched for age (+/-5 years), sex, a...

    journal_title:Neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1212/01.wnl.0000049932.22065.60

    authors: Defazio G,Abbruzzese G,Girlanda P,Buccafusca M,Currà A,Marchese R,Martino D,Masi G,Mazzella L,Vacca L,Livrea P,Berardelli A

    更新日期:2003-03-25 00:00:00

  • Vitamin D, cognition, and dementia: a systematic review and meta-analysis.

    abstract:OBJECTIVE:To examine the association between cognitive function and dementia with vitamin D concentration in adults. METHODS:Five databases were searched for English-language studies up to August 2010, and included all study designs with a comparative group. Cognitive function or impairment was defined by tests of glo...

    journal_title:Neurology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1212/WNL.0b013e31826c197f

    authors: Balion C,Griffith LE,Strifler L,Henderson M,Patterson C,Heckman G,Llewellyn DJ,Raina P

    更新日期:2012-09-25 00:00:00

  • Structural abnormalities in the cerebellum and sensorimotor circuit in writer's cramp.

    abstract:BACKGROUND:Structural abnormalities were detected in bilateral primary sensorimotor areas in writer's cramp. Evidence in other primary dystonia, including blepharospasm and cervical dystonia, suggest that structural abnormalities may be observed in other brain areas such as the cerebellum in writer's cramp. OBJECTIVE:...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000266591.49624.1a

    authors: Delmaire C,Vidailhet M,Elbaz A,Bourdain F,Bleton JP,Sangla S,Meunier S,Terrier A,Lehéricy S

    更新日期:2007-07-24 00:00:00

  • Brainstem auditory evoked potential monitoring: when is change in wave V significant?

    abstract:BACKGROUND:The probability of hearing loss during cerebellopontine angle (CPA) surgery can be reduced by using brainstem auditory evoked potential (BAEP) intraoperative monitoring (IOM). A wave V latency prolongation of 1.0 milliseconds or amplitude decrement of greater than 50% is arbitrarily considered the point when...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000184481.75412.2b

    authors: James ML,Husain AM

    更新日期:2005-11-22 00:00:00

  • Neurosyphilis in AIDS patients: initial CSF VDRL may be negative.

    abstract::We report 2 HIV-seropositive patients with neurosyphilis whose initial CSF VDRL tests were negative. The CSF VDRL became positive after 12 days of IV penicillin treatment for syphilitic meningitis in the 1st patient. The 2nd patient developed syphilitic polyradiculopathy and a positive CSF VDRL 3 months after treatmen...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.40.3_part_1.541

    authors: Feraru ER,Aronow HA,Lipton RB

    更新日期:1990-03-01 00:00:00

  • Cerebrovascular reactivity and vasospasm after subarachnoid hemorrhage: a pilot study.

    abstract::The authors performed serial transcranial Doppler (TCD) and carbon dioxide reactivity (CO2R) testing in 20 aneurysmal subarachnoid hemorrhage patients to determine whether impaired cerebrovascular reactivity was associated with symptomatic vasospasm. Symptomatic vasospasm occurred in 9 of 14 patients with abnormal CO2...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000200777.96896.3d

    authors: Frontera JA,Rundek T,Schmidt JM,Claassen J,Parra A,Wartenberg KE,Temes RE,Mayer SA,Mohr JP,Marshall RS

    更新日期:2006-03-14 00:00:00

  • Miller Fisher syndrome and polyneuritis cranialis in COVID-19.

    abstract:OBJECTIVE:To report 2 patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) who presented acutely with Miller Fisher syndrome and polyneuritis cranialis, respectively. METHODS:Patient data were obtained from medical records from the University Hospital "Príncipe de Asturias," Alcalá de He...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000009619

    authors: Gutiérrez-Ortiz C,Méndez-Guerrero A,Rodrigo-Rey S,San Pedro-Murillo E,Bermejo-Guerrero L,Gordo-Mañas R,de Aragón-Gómez F,Benito-León J

    更新日期:2020-08-04 00:00:00

  • Hyperzincemia in anencephaly and spina bifida: a clue to the pathogenesis of neural tube defects?

    abstract::Zinc is essential for normal embryogenesis and may have particular importance for closure of the human neural tube. Compared to 258 controls, we found increased zinc content in umbilical cord serum in eight of nine newborn anencephalics (p less than 0.02) and three infants with spina bifida (p less than 0.001). Increa...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.34.4.443

    authors: Zimmerman AW

    更新日期:1984-04-01 00:00:00

  • CSF biomarkers predict a more malignant outcome in Alzheimer disease.

    abstract:OBJECTIVE:To investigate if patterns of CSF biomarkers (T-tau, P-tau, and Abeta42) can predict cognitive progression, outcome of cholinesterase inhibitor (ChEI) treatment, and mortality in Alzheimer disease (AD). METHODS:We included outpatients with AD (n = 151) from a prospective treatment study with ChEI. At baselin...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e3181dd4dd8

    authors: Wallin AK,Blennow K,Zetterberg H,Londos E,Minthon L,Hansson O

    更新日期:2010-05-11 00:00:00

  • Absence of genetic linkage of Charcot-Marie-Tooth disease (HMSN Ia) with chromosome 1 gene markers.

    abstract::We previously reported a large Charcot-Marie-Tooth family not linked to the Duffy blood group marker, supporting the existence of genetic heterogeneity in this neuropathy. In order to investigate the possibility of another disease locus on chromosome 1, we analyzed this family further, using DNA polymorphisms of 6 gen...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.39.6.844

    authors: Raeymaekers P,De Jonghe P,Backhovens H,Wehnert A,De Winter G,Swerts L,Gheuens J,Martin JJ,Vandenberghe A,Van Broeckhoven C

    更新日期:1989-06-01 00:00:00

  • Determinants of brain iron in multiple sclerosis: a quantitative 3T MRI study.

    abstract:OBJECTIVES:Abnormal high cerebral iron deposition may be implicated in chronic neurologic disorders, including multiple sclerosis (MS). R2* relaxometry has been recently validated in a postmortem study to indicate brain iron accumulation in a quantitative manner. We used this technique to assess brain iron levels in di...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e318236ef0e

    authors: Khalil M,Langkammer C,Ropele S,Petrovic K,Wallner-Blazek M,Loitfelder M,Jehna M,Bachmaier G,Schmidt R,Enzinger C,Fuchs S,Fazekas F

    更新日期:2011-11-01 00:00:00

  • Efficacy of treatment of MS with IFNbeta-1b or glatiramer acetate by monthly brain MRI in the BECOME study.

    abstract:BACKGROUND:There are no published MRI studies comparing interferon beta 1b (IFNbeta-1b) and glatiramer acetate (GA) for treatment of relapsing multiple sclerosis (MS). OBJECTIVE:To compare the efficacy of IFNbeta-1b and GA for suppression of MS disease activity as evidenced on frequent brain MRI. METHODS:A total of 7...

    journal_title:Neurology

    pub_type: 杂志文章,随机对照试验

    doi:10.1212/01.wnl.0000345970.73354.17

    authors: Cadavid D,Wolansky LJ,Skurnick J,Lincoln J,Cheriyan J,Szczepanowski K,Kamin SS,Pachner AR,Halper J,Cook SD

    更新日期:2009-06-09 00:00:00

  • Genetics of epilepsy: The testimony of twins in the molecular era.

    abstract:OBJECTIVE:Analysis of twins with epilepsy to explore the genetic architecture of specific epilepsies, to evaluate the applicability of the 2010 International League Against Epilepsy (ILAE) organization of epilepsy syndromes, and to integrate molecular genetics with phenotypic analyses. METHODS:A total of 558 twin pair...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000000790

    authors: Vadlamudi L,Milne RL,Lawrence K,Heron SE,Eckhaus J,Keay D,Connellan M,Torn-Broers Y,Howell RA,Mulley JC,Scheffer IE,Dibbens LM,Hopper JL,Berkovic SF

    更新日期:2014-09-16 00:00:00

  • Brain injury, edema, and vascular permeability changes induced by oxygen-derived free radicals.

    abstract::We studied the cerebral effects of oxygen-derived free radicals generated from the xanthine oxidase/hypoxanthine/ADP-Fe3+ system. Xanthine oxidase/hypoxanthine/ADP-Fe3+ solution (0.1 ml) was infused into caudate putamen, and brain was frozen rapidly in situ. Brain water and sodium content increased concomitant with de...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.34.3.315

    authors: Chan PH,Schmidley JW,Fishman RA,Longar SM

    更新日期:1984-03-01 00:00:00

  • Medial temporal lobe atrophy on MRI scans and the diagnosis of Alzheimer disease.

    abstract:BACKGROUND:Despite convenience, accessibility, and strong correlation to severity of Alzheimer disease (AD) pathology, medial temporal lobe atrophy (MTA) has not been used as a criterion in the diagnosis of prodromal and probable AD. METHODS:Using a newly validated visual rating system, mean MTA scores of three bilate...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000336925.79704.9f

    authors: Duara R,Loewenstein DA,Potter E,Appel J,Greig MT,Urs R,Shen Q,Raj A,Small B,Barker W,Schofield E,Wu Y,Potter H

    更新日期:2008-12-09 00:00:00

  • Canine and human myasthenia gravis autoantibodies recognize similar regions on the acetylcholine receptor.

    abstract::Serum from 35 cases of naturally occurring acquired canine myasthenia gravis (MG) were assayed for patterns of autoantibody specificities against canine acetylcholine receptor (AChR) using monoclonal antibodies (mAbs) and antiserum against defined regions of the AChR as competitive inhibitors of autoantibody binding. ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.38.9.1417

    authors: Shelton GD,Cardinet GH,Lindstrom JM

    更新日期:1988-09-01 00:00:00

  • Focal Alzheimer's disease.

    abstract::Alzheimer's disease is characterized by relative sparing of primary sensory and motor cortex and a lack of sensory or motor symptomatology. We report a case of presenile onset dementia accompanied by a slowly progressive hemiparesis. Autopsy examination showed severe pathologic involvement of somatosensory cortex with...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.40.1.14

    authors: Jagust WJ,Davies P,Tiller-Borcich JK,Reed BR

    更新日期:1990-01-01 00:00:00

  • Prediction of pathology in primary progressive language and speech disorders.

    abstract:OBJECTIVE:Frontotemporal lobar degeneration (FTLD) encompasses a variety of clinicopathologic entities. The antemortem prediction of the underlying pathologic lesions is reputed to be difficult. This study sought to characterize correlations between 1) the different clinical variants of primary progressive language and...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e3181c7198e

    authors: Deramecourt V,Lebert F,Debachy B,Mackowiak-Cordoliani MA,Bombois S,Kerdraon O,Buée L,Maurage CA,Pasquier F

    更新日期:2010-01-05 00:00:00

  • Loss of independence in early Parkinson disease: A 5-year population-based incident cohort study.

    abstract:OBJECTIVE:To determine the risk, predictors, and prognosis of independence loss and institutionalization in patients with early Parkinson disease (PD). METHODS:We conducted a prospective population-based 5-year longitudinal study following 189 patients with incident PD and 174 controls matched for age, sex, and comorb...

    journal_title:Neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1212/WNL.0000000000003213

    authors: Bjornestad A,Tysnes OB,Larsen JP,Alves G

    更新日期:2016-10-11 00:00:00

  • Leigh-type neuropathology in Pearson syndrome associated with impaired ATP production and a novel mtDNA deletion.

    abstract::Pearson syndrome is a systemic disorder of oxidative phosphorylation in infants, predominantly affecting the bone marrow and exocrine pancreas and associated with single deletions in mitochondrial DNA (mtDNA). CNS involvement may occur in patients who survive the infantile hematopoietic disorder. We describe a Pearson...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.47.5.1320

    authors: Santorelli FM,Barmada MA,Pons R,Zhang LL,DiMauro S

    更新日期:1996-11-01 00:00:00

  • Orthostatic tremor: Clinical, electrophysiologic, and treatment findings in 184 patients.

    abstract:OBJECTIVE:To evaluate the clinical, electrophysiologic, and treatment outcome features of orthostatic tremor (OT) in a large case series. METHODS:We performed medical record review of 184 patients who met clinical and electrodiagnostic criteria for OT from 1976 to 2013 at the Mayo Clinic. Demographic, clinical, electr...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000002328

    authors: Hassan A,Ahlskog JE,Matsumoto JY,Milber JM,Bower JH,Wilkinson JR

    更新日期:2016-02-02 00:00:00

  • Thrombolytic stroke therapy: past, present, and future.

    abstract::Until 1995, treatment of strokes consisted exclusively of efforts to prevent recurrence. Proof that tissue plasminogen activator is useful for acute management is changing the approach to stroke patients. The development process has been difficult and the current treatment recommendations have been controversial. Rece...

    journal_title:Neurology

    pub_type: 杂志文章,评审

    doi:10.1212/wnl.53.1.14

    authors: Zivin JA

    更新日期:1999-07-13 00:00:00

  • A Wallerian degeneration pattern in patients at risk for MS.

    abstract:BACKGROUND:Demyelination alone may not explain the progressive disability that frequently develops in MS. An alternative explanation for irreversible disability assumes a contribution from axonal injury or loss. In theory, axonal injury may occur in the focal areas characterized by early inflammation, or can be more di...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.54.5.1155

    authors: Simon JH,Kinkel RP,Jacobs L,Bub L,Simonian N

    更新日期:2000-03-14 00:00:00

  • Long-term interferon beta-1b therapy for MS: is routine thyroid assessment always useful?

    abstract:BACKGROUND:The authors previously reported on the development of thyroid dysfunction and autoimmunity during 1-year treatment of patients with MS with interferon-beta 1b (IFN beta-1b). OBJECTIVE:To evaluate the evolution of incident thyroid disease and the possible development of more thyroid disease during longer ter...

    journal_title:Neurology

    pub_type: 临床试验,杂志文章

    doi:10.1212/wnl.55.4.549

    authors: Monzani F,Caraccio N,Casolaro A,Lombardo F,Moscato G,Murri L,Ferrannini E,Meucci G

    更新日期:2000-08-22 00:00:00