Abstract:
:A 28-year-old nonimmunocompromised man developed secondary syphilis confirmed by serum and CSF findings. His course was complicated by chorioretinitis, extensive skin lesions, and spastic paraparesis secondary to syphilitic meningomyelitis. MRI of the spinal cord was strikingly abnormal.
journal_name
Neurologyjournal_title
Neurologyauthors
Strom T,Schneck SAdoi
10.1212/wnl.41.2_part_1.325subject
Has Abstractpub_date
1991-02-01 00:00:00pages
325-6issue
2 ( Pt 1)eissn
0028-3878issn
1526-632Xjournal_volume
41pub_type
杂志文章相关文献
NEUROLOGY文献大全abstract::Single motor unit firing rates were measured from the first dorsal interosseous muscle (FDI) of normal subjects and patients with partial denervation of that muscle. Motor unit discharges were recorded at various levels of voluntary, stationary, isometric contraction of the FDI. The mean increase in firing rate associ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.28.12.1241
更新日期:1978-12-01 00:00:00
abstract::Subacute necrotizing encephalopathy (SNE) or Leigh's disease is associated with various defects in oxidative phosphorylation (OXPHOS). However, the relationships between these OXPHOS defects and nuclear DNA or mitochondrial DNA (mtDNA) mutations is still unclear. We evaluated three SNE pedigrees (two singleton cases a...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.42.11.2168
更新日期:1992-11-01 00:00:00
abstract::We studied a patient in a minimally conscious state using PET and cognitive evoked potentials. Cerebral metabolism was below half of normal values. Auditory stimuli with emotional valence (infant cries and the patient's own name) induced a much more widespread activation than did meaningless noise; the activation patt...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000137421.30792.9b
更新日期:2004-09-14 00:00:00
abstract::Visual hallucinations (VHs) occur frequently in Parkinson's disease (PD). VHs occur more frequently in elderly patients with longer duration of illness, cognitive impairment, and sleep disturbances. The relationship between the use of antiparkinsonian drugs and VHs is complicated, but most drugs used to treat parkinso...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/wnl.63.8_suppl_3.s28
更新日期:2004-10-26 00:00:00
abstract:BACKGROUND:According to widely used criteria (Bohan and Peter criteria, 1975), dermatomyositis (DM) is differentiated from polymyositis (PM) only by skin changes. More recent criteria also include histopathologic characteristics enabling the distinction between PM and DM and the differentiation of sporadic inclusion bo...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.61.3.316
更新日期:2003-08-12 00:00:00
abstract::To identify clinical and electrophysiologic features related to IV immunoglobulin (IVIg) responsiveness in chronic inflammatory demyelinating polyneuropathy (CIDP), the authors conducted a multicenter study on 312 patients with CIDP (199 responders and 113 nonresponders). Muscle atrophy and decreased compound muscle a...
journal_title:Neurology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1212/01.WNL.0000158680.89323.F8
更新日期:2005-04-26 00:00:00
abstract::A group of 204 muscular dystrophy patients were screened for immunohistochemical and biochemical alpha-sarcoglycan defect and their DNA was analyzed for pathogenetic mutation in the four sarcoglycan genes. We identified 21 patients with alpha-, beta-, or gamma-sarcoglycan gene mutations. Patients with alpha-sarcoglyca...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.52.1.176
更新日期:1999-01-01 00:00:00
abstract::Epilepsy is common in people with intellectual and developmental disabilities (IDD). In adulthood, patients with IDD and epilepsy (IDD-E) have neurologic, psychiatric, medical, and social challenges compounded by fragmented and limited care. With increasing neurologic disability, there is a higher frequency of epileps...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/WNL.0000000000002060
更新日期:2015-10-27 00:00:00
abstract::A patient received an overdose of intravascular contrast medium and experienced protracted seizures associated with radiographic evidence of prolonged retention of the contrast agent in the cerebral cortex, basal ganglia, and thalami. This is only the second report and the first survivor of a similar neurologic syndro...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.43.4.836
更新日期:1993-04-01 00:00:00
abstract::Acute in-stent thrombosis is a well-known complication of carotid angioplasty and stenting (CAS) and often due to resistance to or inadequate treatment with platelet-inhibiting agents. The authors report three cases of a delayed in-stent thrombosis after more than a week but less than 3 months after CAS. In all cases,...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000216141.01262.77
更新日期:2006-05-23 00:00:00
abstract::We examined serum-mediated cytotoxicity on cultured rat oligodendrocytes, using serum from patients with acute or chronic progressive multiple sclerosis and normal controls. We found heat-labile serum factors in serum from MS and also in controls. The cytotoxic effects of MS and normal sera were not restored by adding...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.36.2.276
更新日期:1986-02-01 00:00:00
abstract:OBJECTIVE:APOE ε2 and ε4 alleles have been associated with lobar intracerebral hemorrhage (ICH) in predominately white populations; we sought to evaluate whether this held true among black and Hispanic populations. METHODS:The Ethnic/Racial Variations of Intracerebral Hemorrhage study is a prospective, multicenter cas...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000005908
更新日期:2018-07-31 00:00:00
abstract::Thirty-one individuals awaiting trial or sentencing for murder or undergoing an appeal process requested a neurologic examination through legal counsel. We attempted in each instance to obtain EEG, MRI or CT, and neuropsychological testing. Neurologic examination revealed evidence of "frontal" dysfunction in 20 (64.5%...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.45.9.1641
更新日期:1995-09-01 00:00:00
abstract:BACKGROUND:Deep brain stimulation of the internal global pallidus (GPi) and the subthalamic nucleus (STN) has become a treatment alternative in advanced PD. Although the effects of GPi stimulation have been examined recently, little is known about STN stimulation effects on motor cortex excitability. METHODS:The effec...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.59.5.700
更新日期:2002-09-10 00:00:00
abstract:BACKGROUND:HIV infection is associated with a painful distal sensory polyneuropathy (DSP) that can severely limit the quality of life of affected subjects. The pathogenesis of DSP is unknown, although both HIV proteins and products of immune activation triggered by HIV infection have been implicated. OBJECTIVE:To asse...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.WNL.0000152981.32057.BB
更新日期:2005-03-08 00:00:00
abstract::We examined the cassette-recorded 24-hour ambulatory EEG findings in children who had either clinically definite seizures or episodic behavioral disturbances not regarded as epileptic on clinical grounds. Among 40 epileptic patients, 22 had one or more attacks during the 24-hour recording session. In 15 of these patie...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.38.4.558
更新日期:1988-04-01 00:00:00
abstract:OBJECTIVE:To compare the prognostic accuracy of various acute stroke prognostic scales using a large, independent, clinical trials dataset. METHODS:We directly compared 8 stroke prognostic scales, chosen based on focused literature review (Acute Stroke Registry and Analysis of Lausanne [ASTRAL]; iSCORE; iSCORE-revised...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000004332
更新日期:2017-09-05 00:00:00
abstract::Seizures are not expected in progressive multifocal leukoencephalopathy (PML), a condition considered to be restricted to the white matter. Review of medical records of 89 patients with possible or proven PML showed an 18% prevalence of seizures. Seizures usually responded well to treatment and did not affect survival...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000194227.16696.11
更新日期:2006-01-24 00:00:00
abstract:OBJECTIVE:To report our experience delivering intrathecal nusinersen through cervical puncture in patients with spinal muscular atrophy (SMA) with no lumbar access. BACKGROUND:SMA is a neuromuscular disorder characterized by profound muscle weakness, atrophy, and paralysis due to degeneration of the anterior horn cell...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000006006
更新日期:2018-08-14 00:00:00
abstract:OBJECTIVE:To review clinical and electrodiagnostic features of the medial brachial fascial compartment syndrome, a complication of percutaneous axillary vessel puncture. METHODS:The authors reviewed electrodiagnostic examinations over a 20-year period. RESULTS:This syndrome presents with weakness, pain, and numbness ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000089488.35632.08
更新日期:2003-10-28 00:00:00
abstract::The mitochondrial genome has an underdeveloped "DNA repair repertoire" compared with the nuclear genome, making the mitochondrial DNA more susceptible to mutations by endogenous factors such as defects of the mitochondrial polymerase itself, and by exogenous factors such as radiation and UV light. Increased sensitivit...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/wnl.43.2.280
更新日期:1993-02-01 00:00:00
abstract::Gamma hydroxybutyrate was administered to adult cats by intravenous infusion at varying dosages while an electroencephalogram (EEG) was recorded from electrodes placed stereotactically in the right and left hippocampus and thalamic intralaminar nucleus and from cortical electrodes. Blood cerebrospinal fluid samples we...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.26.1.51
更新日期:1976-01-01 00:00:00
abstract:OBJECTIVES:The Stroke-Thrombolytic Predictive Instrument (Stroke-TPI) predicts the probability of good and bad outcomes with and without recombinant tissue plasminogen activator (rtPA). We sought to rebuild and externally validate a simpler Stroke-TPI to support implementation in routine clinical care. METHODS:Using t...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000001925
更新日期:2015-09-15 00:00:00
abstract::The effect of phenytoin (PHT) concentration on the elimination rate of PHT was evaluated in infants, children, and young adults ranging in age from 1 day to 22 years. As PHT concentration increased, the effective half-life (t50%) increased. In eight children, age 7 months to 4.83 years with initial concentrations betw...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.30.2.196
更新日期:1980-02-01 00:00:00
abstract:OBJECTIVE:To investigate whether impaired spatial memory contributes to cognitive deficits in idiopathic cervical dystonia (ICD). METHODS:The authors tested 16 untreated patients with ICD and 16 healthy controls with four variants of a classic spatial memory task, in which subjects were requested to recall the locatio...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.WNL.0000161869.83783.05
更新日期:2005-05-24 00:00:00
abstract::Antiepileptic drug (AED) selection in women of reproductive age should consider efficacy, tolerability, interactions with contraceptive medications, and teratogenicity. Women planning a pregnancy should be counseled regarding the need for compliance with therapy and the risk for birth defects. All women with epilepsy ...
journal_title:Neurology
pub_type: 共识发展会议,杂志文章,评审
doi:10.1212/wnl.51.5_suppl_4.s21
更新日期:1998-11-01 00:00:00
abstract::Moderate hypothermia (33 degrees C) was induced for 7 and 3 days, respectively, in two patients with multiple sclerosis. In both patients, striking improvement of clinical signs persisted throughout the period of cooling, indicating the potential for sustained reversal of the neurologic deficit. Hypothermia may aid ma...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.27.3.302
更新日期:1977-03-01 00:00:00
abstract::In 11 patients with chronic inflammatory demyelinating polyneuropathy (CIDP) and 11 patients with chronic idiopathic axonal polyneuropathy (CIAP), absent myotatic reflexes were significantly associated more often with CIDP than with CIAP, an absent biceps-reflex having the highest sensitivity and specificity for the d...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.53.7.1573
更新日期:1999-10-22 00:00:00
abstract::Since a parental sex effect has been reported in Huntington's disease, we looked to see whether a similar effect is apparent in adult (autosomal dominant) familial ALS. We analyzed the data for 145 patients, with an onset age range of 20 to 68 years and a known affected parent (AP), from 52 families described in the l...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/wnl.41.8.1292
更新日期:1991-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Human herpesvirus 8 (HHV-8) has been found in association with Kaposi's sarcomas in human immunodeficiency virus (HIV)-positive and -negative patients, primary effusion lymphomas (PELs), multicentric Castleman's disease, and multiple myeloma. The PELs share several features with acquired immuno...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.50.2.335
更新日期:1998-02-01 00:00:00