Abstract:
:Visual hallucinations (VHs) occur frequently in Parkinson's disease (PD). VHs occur more frequently in elderly patients with longer duration of illness, cognitive impairment, and sleep disturbances. The relationship between the use of antiparkinsonian drugs and VHs is complicated, but most drugs used to treat parkinsonian motor symptoms induce VHs and psychosis in some PD patients. The "continuum hypothesis" proposing that medication-induced psychiatric symptoms in PD begin with drug-induced sleep disturbances, followed by vivid dreams, with progression to hallucinatory and delusional experiences has been challenged. In some patients, VHs may represent intrusion of REM sleep-related imagery into wakefulness. Improving REM sleep abnormalities in PD (e.g., stimulants, anticholinesterase inhibitors) is one strategy now being tested to improve VHs in PD.
journal_name
Neurologyjournal_title
Neurologyauthors
Kulisevsky J,Roldan Edoi
10.1212/wnl.63.8_suppl_3.s28subject
Has Abstractpub_date
2004-10-26 00:00:00pages
S28-30issue
8 Suppl 3eissn
0028-3878issn
1526-632Xpii
63/8_suppl_3/S28journal_volume
63pub_type
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