Spinal cord injury and type 2 diabetes: results from a population health survey.

Abstract:

OBJECTIVE:The objective of this study was to evaluate the association between spinal cord injury (SCI) and type 2 diabetes in a large representative sample and to determine whether an association exists irrespective of known risk factors for type 2 diabetes. METHODS:Data were obtained on 60,678 respondents to the Statistics Canada 2010 Cycle of the cross-sectional Canadian Community Health Survey. Multivariable logistic regression, incorporating adjustment for confounders and probability weights to account for the Canadian Community Health Survey sampling method, was conducted to quantify this association. RESULTS:After adjustment for both sex and age, SCI was associated with a significant increased odds of type 2 diabetes (adjusted odds ratio = 1.66, 95% confidence interval 1.16-2.36). These heightened odds persisted after additional adjustment for smoking status, hypertension status, body mass index, daily physical activity, alcohol intake, and daily consumption of fruits and vegetables (fully adjusted odds ratio = 2.45, 95% confidence interval 1.34-4.47). CONCLUSIONS:There is a strong association between SCI and type 2 diabetes, which is not explained by known risk factors for type 2 diabetes.

journal_name

Neurology

journal_title

Neurology

authors

Cragg JJ,Noonan VK,Dvorak M,Krassioukov A,Mancini GB,Borisoff JF

doi

10.1212/01.wnl.0000436074.98534.6e

subject

Has Abstract

pub_date

2013-11-19 00:00:00

pages

1864-8

issue

21

eissn

0028-3878

issn

1526-632X

pii

01.wnl.0000436074.98534.6e

journal_volume

81

pub_type

杂志文章
  • Plasmapheresis in multiple sclerosis: prospective trial of pheresis and immunosuppression versus immunosuppression alone.

    abstract::A prospective trial of plasmapheresis and azathioprine or azathioprine alone was carrier out on 20 patients with chronic progressive MS. Seven of 10 patients in each group continued therapy for 12 months. When the groups were compared by disability ratings, the combination of plasmapheresis and azathioprine was no bet...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.32.7.739

    authors: Tindall RS,Walker JE,Ehle AL,Near L,Rollins J,Becker D

    更新日期:1982-07-01 00:00:00

  • Apraxia during Wada testing.

    abstract::Apraxia is the loss of the ability to perform learned skilled movements correctly. In right-handers, apraxia and aphasia are most frequently associated with left-hemisphere lesions. When they are dissociated, however, aphasia is more common in the absence of apraxia than vice versa. There are two hypotheses that can a...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.45.7.1379

    authors: Foundas AL,Henchey R,Gilmore RL,Fennell EB,Heilman KM

    更新日期:1995-07-01 00:00:00

  • Hydromyelia associated with arrested hydrocephalus.

    abstract::A 16-year-old male with a 9-year history of spontaneously arrested hydrocephalus was noted to have hydrosyringomyelia and increased intracranial pressure shortly after sustaining minor head trauma. His symptoms resolved completely following ventriculoperitoneal shunt replacement. Hydrosyringomyelia may occur in the se...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.38.4.652

    authors: Olson DM,Milstein JM

    更新日期:1988-04-01 00:00:00

  • Distinct brain networks underlie cognitive dysfunction in Parkinson and Alzheimer diseases.

    abstract:OBJECTIVE:To determine whether cognitive impairment in Parkinson disease (PD) and Alzheimer disease (AD) derives from the same network pathology. METHODS:We analyzed 18F-fluorodeoxyglucose PET scans from 40 patients with AD and 40 age-matched healthy controls from the Alzheimer's Disease Neuroimaging Initiative and sc...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000003285

    authors: Mattis PJ,Niethammer M,Sako W,Tang CC,Nazem A,Gordon ML,Brandt V,Dhawan V,Eidelberg D

    更新日期:2016-11-01 00:00:00

  • Psychological stress as risk factor for exacerbations in multiple sclerosis.

    abstract::We prospectively evaluated the relationship between a common psychological stressor and relapses in multiple sclerosis (MS) in a group of 32 MS patients exposed to the threat of missile attacks during the Persian Gulf War of 1991. The number of relapses during the war and the following 2 months was significantly lower...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.43.7.1311

    authors: Nisipeanu P,Korczyn AD

    更新日期:1993-07-01 00:00:00

  • The effect of bilateral visual cortex lesions on the development of eye movements and perception.

    abstract::We studied the eye movements and visual perception in a man with extensive bilateral occipital lesions acquired at birth. He had 3/500 acuity, limited visual fields, and extrafoveal fixation attributable to an intact left superior visual cortex. Analysis of digitized electro-oculography and magnetic search coil data s...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.39.3.406

    authors: Rizzo M,Hurtig R

    更新日期:1989-03-01 00:00:00

  • Effectiveness of opicapone and switching from entacapone in fluctuating Parkinson disease.

    abstract:OBJECTIVE:To evaluate the effectiveness of opicapone as add-on to levodopa and the effects of switching from entacapone over 1 year of treatment in patients with fluctuating Parkinson disease. METHODS:After completion of a placebo- and entacapone-controlled double-blind study of opicapone (5, 25, or 50 mg), 495 patien...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000005557

    authors: Ferreira JJ,Lees AJ,Poewe W,Rascol O,Rocha JF,Keller B,Soares-da-Silva P

    更新日期:2018-05-22 00:00:00

  • Frontal lobe neglect in monkeys.

    abstract::Using a crossed-response task, monkeys with neglect induced by frontal lesions appear to have motor rather than sensory neglect. However, the crossed-response task may not reveal sensory neglect (inattention) if no perceptual discrimination is required. We therefore trained two monkeys in a perceptually complex crosse...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.45.6.1205

    authors: Heilman KM,Valenstein E,Day A,Watson R

    更新日期:1995-06-01 00:00:00

  • Primary lateral sclerosis as a phenotypic manifestation of familial ALS.

    abstract::Primary lateral sclerosis (PLS) is a diagnosis of exclusion in patients with progressive spinobulbar spasticity and could be part of the clinical spectrum of ALS. Unlike ALS, which is familial in 5 to 10% of the cases, PLS has been described as a sporadic disorder in adults. The authors report two patients with PLS fr...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.WNL.0000162033.47893.F7

    authors: Brugman F,Wokke JH,Vianney de Jong JM,Franssen H,Faber CG,Van den Berg LH

    更新日期:2005-05-24 00:00:00

  • Recent advances in the treatment of orthostatic hypotension.

    abstract::Orthostatic hypotension is a fall in blood pressure on standing that causes symptoms of dizziness, visual changes, and discomfort in the head and neck. The goal of treatment is the improvement of the patient's functional capacity, rather than a target blood pressure. For treatment to be successful, it must be individu...

    journal_title:Neurology

    pub_type: 杂志文章,评审

    doi:

    authors: Robertson D,Davis TL

    更新日期:1995-04-01 00:00:00

  • Tapping linked to function and structure in premanifest and symptomatic Huntington disease.

    abstract:OBJECTIVE:Motor signs are functionally disabling features of Huntington disease. Characteristic motor signs define disease manifestation. Their severity and onset are assessed by the Total Motor Score of the Unified Huntington's Disease Rating Scale, a categorical scale limited by interrater variability and insensitivi...

    journal_title:Neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1212/WNL.0b013e3182020123

    authors: Bechtel N,Scahill RI,Rosas HD,Acharya T,van den Bogaard SJ,Jauffret C,Say MJ,Sturrock A,Johnson H,Onorato CE,Salat DH,Durr A,Leavitt BR,Roos RA,Landwehrmeyer GB,Langbehn DR,Stout JC,Tabrizi SJ,Reilmann R

    更新日期:2010-12-14 00:00:00

  • Prevalence of multiple sclerosis in the Parsis of Bombay.

    abstract::We carried out a door-to-door-survey to screen a community of 14,010 people (Parsis living in colonies in Bombay, India) for possible neurologic diseases, and used defined diagnostic criteria to evaluate people who tested positive on the screening survey. There were three clinically definite cases of multiple sclerosi...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.38.5.727

    authors: Bharucha NE,Bharucha EP,Wadia NH,Singhal BS,Bharucha AE,Bhise AV,Kurtzke JF,Schoenberg BS

    更新日期:1988-05-01 00:00:00

  • Self-awareness of migraine: interpreting the labels that headache sufferers apply to their headaches.

    abstract::Although people with migraine are aware of their headaches they are often not aware that they have migraine. This can lead to inappropriate or ineffective use of treatments, delays in seeking appropriate care, and miscommunication during clinical encounters. This article assesses self-recognition of migraine and ident...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.58.9_suppl_6.s21

    authors: Lipton RB,Stewart WF,Liberman JN

    更新日期:2002-05-14 00:00:00

  • Long-term association between seizure outcome and depression after resective epilepsy surgery.

    abstract:OBJECTIVE:This study explored the association between long-term epilepsy surgery outcome and changes in depressive symptoms. METHODS:Adults were enrolled between 1996 and 2001 in a multicenter prospective study to evaluate outcomes of resective epilepsy surgery. The extent of depressive symptoms and depression case st...

    journal_title:Neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1212/WNL.0b013e31823a0c90

    authors: Hamid H,Liu H,Cong X,Devinsky O,Berg AT,Vickrey BG,Sperling MR,Shinnar S,Langfitt JT,Walczak TS,Barr WB,Dziura J,Bazil CW,Spencer SS

    更新日期:2011-11-29 00:00:00

  • Detection and cellular localization of enterovirus RNA sequences in spinal cord of patients with ALS.

    abstract:OBJECTIVE:To investigate the possible association of persistent enterovirus (EV) infection with the development of ALS. BACKGROUND:Although ALS is a clinically well-defined motor neuron disease, little is known about the etiology and pathogenesis of the sporadic cases. Among the different causes that have been hypothe...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.54.1.20

    authors: Berger MM,Kopp N,Vital C,Redl B,Aymard M,Lina B

    更新日期:2000-01-11 00:00:00

  • Idiopathic cervical dystonia: an overview.

    abstract::Idiopathic cervical dystonia (CD) is the most common of the adult-onset focal dystonias. It manifests as involuntary muscle contractions that cause twisting or turning of the neck. The resulting abnormal head and neck postures are heterogeneous in their presentation. Because of the variable presentation of the disease...

    journal_title:Neurology

    pub_type: 杂志文章,评审

    doi:

    authors: Stacy M

    更新日期:2000-01-01 00:00:00

  • Use of amyloid-PET to determine cutpoints for CSF markers: A multicenter study.

    abstract:OBJECTIVES:To define CSF β-amyloid 1-42 (Aβ42) cutpoints to detect cortical amyloid deposition as assessed by 11C-Pittsburgh compound B ([11C]PiB)-PET and to compare these calculated cutpoints with cutpoints currently used in clinical practice. METHODS:We included 433 participants (57 controls, 99 with mild cognitive ...

    journal_title:Neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1212/WNL.0000000000002081

    authors: Zwan MD,Rinne JO,Hasselbalch SG,Nordberg A,Lleó A,Herukka SK,Soininen H,Law I,Bahl JM,Carter SF,Fortea J,Blesa R,Teunissen CE,Bouwman FH,van Berckel BN,Visser PJ

    更新日期:2016-01-05 00:00:00

  • Brain atrophy and lesion load in a large population of patients with multiple sclerosis.

    abstract:OBJECTIVE:To measure white matter (WM) and gray matter (GM) atrophy and lesion load in a large population of patients with multiple sclerosis (MS) using a fully automated, operator-independent, multiparametric segmentation method. METHODS:The study population consisted of 597 patients with MS and 104 control subjects....

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000168837.87351.1f

    authors: Tedeschi G,Lavorgna L,Russo P,Prinster A,Dinacci D,Savettieri G,Quattrone A,Livrea P,Messina C,Reggio A,Bresciamorra V,Orefice G,Paciello M,Brunetti A,Coniglio G,Bonavita S,Di Costanzo A,Bellacosa A,Valentino P,Quar

    更新日期:2005-07-26 00:00:00

  • Insights into the natural history of spontaneous intracranial hypotension from infusion testing.

    abstract:OBJECTIVE:To assess the pathophysiologic changes in patients with spontaneous intracranial hypotension (SIH) based on measures of CSF dynamics, and on the duration of symptoms, in a retrospective case-controlled study. METHODS:We included consecutive patients investigated for SIH at our department from January 2012 to...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000009812

    authors: Häni L,Fung C,Jesse CM,Ulrich CT,Miesbach T,Cipriani DR,Dobrocky T,Z'Graggen WJ,Raabe A,Piechowiak EI,Beck J

    更新日期:2020-07-21 00:00:00

  • Myasthenia gravis: monoclonal antihuman acetylcholine receptor antibodies used to analyze antibody specificities and responses to treatment.

    abstract::We investigated the heterogeneity of serum antibodies to acetylcholine receptor (AChR) by competition with nine antihuman monoclonal antibodies in a cross-sectional study of 36 patients with myasthenia gravis (MG), and in three who showed clinical improvement associated with decrease in total anti-AChR following immun...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.36.5.612

    authors: Whiting PJ,Vincent A,Newsom-Davis J

    更新日期:1986-05-01 00:00:00

  • Association of Time of Day When Endovascular Therapy for Stroke Starts and Functional Outcome.

    abstract:OBJECTIVE:To investigate the association between EVT start time in acute ischemic stroke (AIS) and mid-term functional outcome. METHODS:This retrospective cohort study included all AIS cases treated with EVT from two stroke center registries from January 2012 to December 2018. The primary outcome was the score on the ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000011449

    authors: Hajdu SD,Kaesmacher J,Michel PP,Sirimarco G,Knebel JF,Bartolini B,Kurmann CC,Puccinelli F,Mosimann PJ,Bonvin C,Arnold PM,Niederhäuser J,Eskandari A,Mordasini P,Gralla PJ,Fischer PU,Saliou PG

    更新日期:2021-01-04 00:00:00

  • The functional anatomy of gaze-evoked tinnitus and sustained lateral gaze.

    abstract:OBJECTIVE:To identify neural sites associated with gaze-evoked tinnitus (GET), an unusual condition that may follow cerebellar-pontine angle surgery. METHODS:The authors examined eight patients with GET and used PET to map the neural sites activated by lateral gaze in them and seven age- and sex-matched control subjec...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.56.4.472

    authors: Lockwood AH,Wack DS,Burkard RF,Coad ML,Reyes SA,Arnold SA,Salvi RJ

    更新日期:2001-02-27 00:00:00

  • Computed tomographic angiography for diagnosis of brain death.

    abstract::The authors report two patients with suspected brain death who required confirmatory tests other than clinical examination because of prolonged barbiturate administration for intracranial hypertension. Absence of intracranial blood flow was documented on CT angiography and confirmed by CT perfusion images. Cerebral an...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.62.4.652

    authors: Qureshi AI,Kirmani JF,Xavier AR,Siddiqui AM

    更新日期:2004-02-24 00:00:00

  • Familial X-linked myalgia and cramps: a nonprogressive myopathy associated with a deletion in the dystrophin gene.

    abstract::We report a family with an X-linked recessive disorder characterized by muscle cramps and myalgia. Nine affected male family members had high resting serum levels of creatine kinase, and well-developed musculature with calf hypertrophy but no evidence of muscular weakness. Symptoms began in childhood and did not progr...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.39.10.1277

    authors: Gospe SM Jr,Lazaro RP,Lava NS,Grootscholten PM,Scott MO,Fischbeck KH

    更新日期:1989-10-01 00:00:00

  • NT-proBNP, blood pressure, and cognitive decline in the oldest old: The Leiden 85-plus Study.

    abstract:OBJECTIVE:To study the relation between N-terminal pro-brain natriuretic peptide (NT-proBNP) levels, used as a marker of heart failure in clinical practice, blood pressure (BP), and cognitive decline in the oldest old. METHODS:In 560 participants of the Leiden 85-plus Study, we measured NT-proBNP levels and BP at age ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000000820

    authors: van Vliet P,Sabayan B,Wijsman LW,Poortvliet RK,Mooijaart SP,de Ruijter W,Gussekloo J,de Craen AJ,Westendorp RG

    更新日期:2014-09-23 00:00:00

  • Structural brain alterations can be detected early in HIV infection.

    abstract:OBJECTIVE:Brain changes occurring early in HIV infection are not well characterized. The Chicago Early HIV Infection Study aimed to evaluate the presence and extent of structural brain alterations using quantitative MRI. METHODS:Forty-three HIV and 21 control subjects were enrolled. Mean length of infection was estima...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e318278b5b4

    authors: Ragin AB,Du H,Ochs R,Wu Y,Sammet CL,Shoukry A,Epstein LG

    更新日期:2012-12-11 00:00:00

  • Root stimulation studies in the evaluation of patients with motor neuron disease.

    abstract::Nerve root stimulation may be employed in patients with motor neuron disease (MND) to rule out motor neuropathy with conduction block. The diagnostic utility of these studies is unknown, in part because the range of amplitude changes across nerve root segments in patients with active neuronal degeneration has not been...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.50.6.1907

    authors: Raynor EM,Shefner JM,Ross MH,Logigian EL,Hinchey JA

    更新日期:1998-06-01 00:00:00

  • Natural history of succinic semialdehyde dehydrogenase deficiency through adulthood.

    abstract:OBJECTIVE:The natural history of succinic semialdehyde dehydrogenase (SSADH) deficiency in adulthood is unknown; we elucidate the clinical manifestations of the disease later in life. METHODS:A 63-year-old man with long-standing intellectual disability was diagnosed with SSADH deficiency following hospitalization for ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000001906

    authors: Lapalme-Remis S,Lewis EC,De Meulemeester C,Chakraborty P,Gibson KM,Torres C,Guberman A,Salomons GS,Jakobs C,Ali-Ridha A,Parviz M,Pearl PL

    更新日期:2015-09-08 00:00:00

  • Efficient neurophysiologic selection of X-linked Charcot-Marie-Tooth families: ten novel mutations.

    abstract:OBJECTIVE:To devise a neurophysiologic strategy to select X-linked Charcot-Marie-Tooth neuropathy syndrome (CMTX) families for connexin 32 mutation screening. BACKGROUND:Once the common chromosome 17 DNA duplication (CMT1A syndrome) has been excluded, clinical features are not sufficiently distinctive to select which ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.51.5.1412

    authors: Nicholson GA,Yeung L,Corbett A

    更新日期:1998-11-01 00:00:00

  • Homolateral ataxia and crural paresis: case report.

    abstract::Homolateral ataxia and crural paresis is a recognized vascular syndrome. However, confirmation of the causative lesion rests principally on one earlier case with multiple other infarcts. We studied a patient with the clinical syndrome; computerized tomography revealed a lucency that appeared within 1 week of the infar...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.30.9.1013

    authors: Perman GP,Racy A

    更新日期:1980-09-01 00:00:00