Prefrontal cortical representation of visuospatial working memory in monkeys examined by local inactivation with muscimol.

abstract：:Hypocretin-1 and -2 (Hcrt-1 and -2, also called orexin-A and -B) are newly identified neuropeptides synthesized by hypothalamic neurons. Defects in the Hcrt system underlie the sleep disorder narcolepsy, which is characterized by sleep fragmentation and the involuntary loss of muscle tone called cataplexy. Hcrt neuron...

journal_title：Journal of neurophysiology

authors： Peever JH,Lai YY,Siegel JM

更新日期：2003-05-01 00:00:00

abstract：:Multichannel techniques were used to assess the frequency specificity of activation in the central nucleus of the inferior colliculus (CIC) produced by electrical stimulation of localized regions within the ventral cochlear nucleus (VCN). Data were recorded in response to pure tones from 141 and 193 multiunit clusters...

journal_title：Journal of neurophysiology

authors： Shivdasani MN,Mauger SJ,Rathbone GD,Paolini AG

更新日期：2008-01-01 00:00:00

abstract：:The brain stem nucleus locus coeruleus (LC) is thought to modulate cortical excitability by norepinephrine (NE) release in LC forebrain targets. The effects of LC burst discharge, typically evoked by a strong excitatory input, on cortical ongoing activity are poorly understood. To address this question, we combined di...

journal_title：Journal of neurophysiology

authors： Marzo A,Totah NK,Neves RM,Logothetis NK,Eschenko O

更新日期：2014-06-15 00:00:00

abstract：:The central auditory system has traditionally been divided into lemniscal and nonlemniscal pathways leading from the midbrain through the thalamus to the cortex. This view has served as an organizing principle for studying, modeling, and understanding the encoding of sound within the brain. However, there is evidence ...

journal_title：Journal of neurophysiology

authors： Straka MM,Schmitz S,Lim HH

更新日期：2014-08-15 00:00:00

abstract：:For primary auditory cortex (AI) laminae, there is little evidence of functional specificity despite clearly expressed cellular and connectional differences. Natural sounds are dominated by dynamic temporal and spectral modulations and we used these properties to evaluate local functional differences or constancies ac...

journal_title：Journal of neurophysiology

authors： Atencio CA,Schreiner CE

更新日期：2010-01-01 00:00:00

abstract：:The primate posterior thalamus has been proposed to contribute to pain sensation, but its precise role is unclear. This is in part because spinothalamic tract (STT) neurons that project to the posterior thalamus have received little attention. In this study, antidromic mapping was used to identify individual STT neuro...

journal_title：Journal of neurophysiology

authors： Davidson S,Zhang X,Khasabov SG,Simone DA,Giesler GJ Jr

更新日期：2008-10-01 00:00:00

abstract：:We estimate the rates at which neurons in the primary visual cortex (V1) of anesthetized macaque monkeys transmit stimulus-related information in response to three types of visual stimulus. The stimuli-randomly modulated checkerboard patterns, stationary sinusoidal gratings, and drifting sinusoidal gratings-have very ...

journal_title：Journal of neurophysiology

authors： Reich DS,Mechler F,Victor JD

更新日期：2001-01-01 00:00:00

abstract：:This second paper of the series deals with another issue regarding sensorimotor representations in the CNS that has received much attention, namely the relative weighting of kinematic and kinetic representations. The question we address here is the contribution of muscle tension afferent information in dorsal spinocer...

journal_title：Journal of neurophysiology

authors： Bosco G,Poppele RE

更新日期：2000-05-01 00:00:00

abstract：:The functional significance of vestibular information for the generation of gaze shifts is controversial and less well established than the vestibular contribution to gaze stability. In this study, we asked seven bilaterally avestibular patients to execute voluntary, whole body pivot turns to visual targets up to 180°...

journal_title：Journal of neurophysiology

authors： Anastasopoulos D,Ziavra N,Bronstein AM

更新日期：2019-11-01 00:00:00

abstract：:1. The statistical properties of the bursting potassium channel from fused Torpedo synaptosomes were studied by using patch-clamp recording and time series analysis. 2. Voltage steps produce channel openings; the number of channels opening fluctuates from trial to trial. The maximal current observed in each trial is s...

journal_title：Journal of neurophysiology

authors： Rahamimoff R,Edry-Schiller J,Ginsburg S

更新日期：1992-12-01 00:00:00

abstract：:The activity of the crayfish abdominal postural motoneurons and their associated neurons (the accessory neuron(s) and the MRO(1)) were examined with the aid of techniques for the analysis of simultaneously recorded spike trains. A means of reliably identifying the spikes of the individual motoneurons based on their re...

journal_title：Journal of neurophysiology

authors： Sokolove PG,Tatton WG

更新日期：1975-03-01 00:00:00

abstract：:Capacitance measurements allow direct studies of exocytosis and endocytosis in single synaptic terminals isolated from bipolar neurons of goldfish retina. Extending the technique to intact bipolar cells, with their more complex morphology, requires information about the cells' electrotonic architecture. To this end, w...

journal_title：Journal of neurophysiology

authors： Mennerick S,Zenisek D,Matthews G

更新日期：1997-07-01 00:00:00

abstract：:The responses of cortical neurons to repeated presentation of a stimulus are highly variable, yet correlated. These "noise correlations" reflect a low-dimensional structure of population dynamics. Here, we examine noise correlations in 22,705 pairs of neurons in primary visual cortex (V1) of anesthetized cats, during ...

journal_title：Journal of neurophysiology

authors： Schulz DP,Sahani M,Carandini M

更新日期：2015-08-01 00:00:00

abstract：:To examine the functional interactions between the color and form pathways in the primate visual cortex, we have examined the functional connectivity between pairs of color oriented and nonoriented V1 and V2 neurons in Macaque monkeys. Optical imaging maps for color selectivity, orientation preference, and ocular domi...

journal_title：Journal of neurophysiology

authors： Roe AW,Ts'o DY

更新日期：1999-11-01 00:00:00

abstract：:1. Pharmacologic agents known to modulate long-term potentiation (LTP) at the mossy fiber-to-CA3 pyramidal neuron synapse were tested for their effects on the activity of single voltage-gated calcium channels in adult CA3 pyramidal neurons. 2. Single-channel current recordings of three types of voltage-gated calcium c...

journal_title：Journal of neurophysiology

authors： Fisher R,Johnston D

更新日期：1990-10-01 00:00:00

abstract：:We compared electroretinographic (ERG) responses to uniform-field and a variety of pattern stimuli using both transient and steady-state analyses. Evidence is provided that for all of these stimuli, the peak at high temporal frequencies in the steady-state response corresponds to the fast wave of the transient respons...

journal_title：Journal of neurophysiology

authors： Baker CL Jr,Hess RF

更新日期：1984-05-01 00:00:00

abstract：:The majority of cerebral signals destined for the cerebellum are handed over by the pontine nuclei (PN), which thoroughly reorganize the neocortical topography. The PN maps neocortical signals of wide-spread origins into adjacent compartments delineated by spatially precise distribution of cortical terminals and posts...

journal_title：Journal of neurophysiology

authors： Möck M,Butovas S,Schwarz C

更新日期：2006-06-01 00:00:00

abstract：:An in vitro brain stem-spinal cord preparation from an adult urodele (Pleurodeles waltl) was developed in which two fictive rhythmic motor patterns were evoked by bath application of N-methyl-D-aspartate (NMDA; 2.5-10 microM) with D-serine (10 microM). Both motor patterns displayed left-right alternation. The first pa...

journal_title：Journal of neurophysiology

authors： Delvolvé I,Branchereau P,Dubuc R,Cabelguen JM

更新日期：1999-08-01 00:00:00

abstract：:The rate and the total amount of Ca2+ elevation in the presynaptic terminals of bullfrog sympathetic ganglia depend on the firing frequency of the terminals. Carbonyl cyanide m-chlorophenylhydrazone (CCCP), a mitochondrial uncoupler, was used for testing whether mitochondrial Ca2+ uptake is one of the mechanisms that ...

journal_title：Journal of neurophysiology

authors： Peng YY

更新日期：1998-07-01 00:00:00

abstract：:Modularity in the central nervous system (CNS), i.e., the brain capability to generate a wide repertoire of movements by combining a small number of building blocks ("modules"), is thought to underlie the control of movement. Numerous studies reported evidence for such a modular organization by identifying invariant m...

journal_title：Journal of neurophysiology

authors： Delis I,Panzeri S,Pozzo T,Berret B

更新日期：2014-02-01 00:00:00

abstract：:1. The extracellular activity of 45 antidromically identified spinocervical tract (SCT) neurons responsive to light mechanical stimulation of the glabrous surfaces of the forepaw was examined in raccoons anesthetized with pentobarbital sodium. An additional seven neurons had peripheral receptive fields (RFs) located o...

journal_title：Journal of neurophysiology

authors： Hirata H,Pubols BH Jr

更新日期：1989-01-01 00:00:00

abstract：:The ability of individuals to adapt locomotion to constraints associated with the complex environments normally encountered in everyday life is paramount for survival. Here, we tested the ability of 24 healthy young adults to adapt to a rightward prism shift (∼11.3°) while either walking and stepping to targets (i.e.,...

journal_title：Journal of neurophysiology

authors： Alexander MS,Flodin BW,Marigold DS

更新日期：2011-08-01 00:00:00

abstract：:Neurons integrate subthreshold inputs in a frequency-dependent manner. For sinusoidal stimuli, response amplitudes thus vary with stimulus frequency. Neurons in entorhinal cortex show two types of such resonance behavior: stellate cells in layer II exhibit a prominent peak in the resonance profile at stimulus frequenc...

journal_title：Journal of neurophysiology

authors： Schreiber S,Erchova I,Heinemann U,Herz AV

更新日期：2004-07-01 00:00:00

abstract：:Memory for past events may be based on retrieval accompanied by specific contextual details (recollection) or on the feeling that an item is old (familiarity) or new (novelty) in the absence of contextual details. There are indications that recollection, familiarity, and novelty involve different medial temporal lobe ...

journal_title：Journal of neurophysiology

authors： Daselaar SM,Fleck MS,Cabeza R

更新日期：2006-10-01 00:00:00

abstract：:PSD-95-like, disc-large (DLG) family membrane-associated guanylate kinase proteins (PSD/DLG-MAGUKs) are essential for regulating synaptic AMPA receptor (AMPAR) function and activity-dependent trafficking of AMPARs. Using a molecular replacement strategy to replace endogenous PSD-95 with SAP97β, we show that the protot...

journal_title：Journal of neurophysiology

authors： Liu M,Lewis LD,Shi R,Brown EN,Xu W

更新日期：2014-02-01 00:00:00

abstract：:Limb movement-related neurons in the cerebellar nuclei (CN) typically produce bursts of discharge in association with movement. Consequently, given the inhibitory nature of the Purkinje cell (PC) projection to CN, it is puzzling that only a minority of movement-related PCs pause; the majority burst. Some of the moveme...

journal_title：Journal of neurophysiology

authors： Holdefer RN,Houk JC,Miller LE

更新日期：2005-01-01 00:00:00

abstract：:Several previous studies have shown the existence of Up and Down states and have linked their magnitude (e.g., depolarization level) to the size of sensory-evoked responses. Here, we studied how the temporal dynamics of such states influence the sensory-evoked response to vibrissa deflection. Under alpha-chloralose an...

journal_title：Journal of neurophysiology

authors： Haslinger R,Ulbert I,Moore CI,Brown EN,Devor A

更新日期：2006-09-01 00:00:00

abstract：:We investigated if visual direction-selective neurons in the pretectal area (APT) of goldfish (Carassius auratus auratus) preferred visual stimuli resulting from rotations around axes corresponding to the best responsive axes of the semicircular canals [optic flow that is consistent to a maximal activation of the hori...

journal_title：Journal of neurophysiology

authors： Masseck OA,Hoffmann KP

更新日期：2009-11-01 00:00:00

abstract：:To trigger action potentials in neurons, most investigators use electrical or chemical stimulation. Here we describe an optical stimulation method based on semi-synthetic light-activated ion channels. These SPARK (synthetic photoisomerizable azobenzene-regulated K(+)) channels consist of a synthetic azobenzene-contain...

journal_title：Journal of neurophysiology

authors： Chambers JJ,Banghart MR,Trauner D,Kramer RH

更新日期：2006-11-01 00:00:00

abstract：:1. Intracellular recordings were made from neurons of the basolateral amygdala (BLA) in in vitro slice preparations to determine long-term differences in metabotropic glutamate receptor (mGluR) agonist-induced membrane responses in control and amygdala-kindled rats. 2. (2S,3S,4S)-alpha-(carboxycyclopropyl)glycine-1 (L...

journal_title：Journal of neurophysiology

authors： Holmes KH,Keele NB,Shinnick-Gallagher P

更新日期：1996-10-01 00:00:00