Abstract：
:Transplacental effect of benzo(a)pyrene was studied in organ cultures of embryonic lung tissue explanted from mouse donors injected by the carcinogen. Hyperplastic alteration of epithelium, followed by adenomatous changes were seen in embryonic lung tissue cultures from donor mice injected by benzo(a)pyrene. No alteration was seen in control cultures in which the mice were injected by a non-carcinogenic hydrocarbon (pyrene). Besides the blastomogenic action, a growth-promoting effect of the benzo(a)pyrene was observed in the particular organ cultures of the embryonic lung tissue.
journal_name
Neoplasmajournal_title
Neoplasmaauthors
Shabad LM,Kolesnichenko TS,Nikonova TVsubject
Has Abstractpub_date
1975-01-01 00:00:00pages
113-22issue
2eissn
0028-2685issn
1338-4317journal_volume
22pub_type
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