Abstract：
:Relative content of membrane sectors of ATPase complex in rat liver and Zajdela hepatoma mitochondria and the ability of mitochondrial membrane of the two sources to bind isolated soluble (F1) ATPase were examined. Approximately equal concentrations of oligomycin were required for 50% inhibition of ATPase activity in submitochondrial particles of rat liver and Zajdela hepatoma indicating practically identical content of membrane sectors of ATPase complex in both types of mitochondria. As detected by the increase in oligomycin-sensitive ATPase activity of submitochondrial particles incubated with isolated F1, the submitochondrial particles of Zajdela hepatoma in contrast to those of rat liver were able to bind specifically considerable amounts of exogenously added F1. The results indicate that mitochondria of Zajdela hepatoma contain membrane sectors of ATPase complex unassociated with F1 but capable of association with this enzyme.
journal_name
Neoplasmajournal_title
Neoplasmaauthors
Kuzela S,Kolarov J,Krempaský V,Luciaková K,Ujházy Vsubject
Has Abstractpub_date
1978-01-01 00:00:00pages
745-9issue
6eissn
0028-2685issn
1338-4317journal_volume
25pub_type
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