ZNF139 promotes tumor metastasis by increasing migration and invasion in human gastric cancer cells.

abstract：:HCC is one of the leading causes of death worldwide. Liver transplantation including living donor transplantation is the best available treatment. We have analyzed our experience with LDLT in patients with HCC and HCV in order to determine if alpha feto-protein (AFP) is a better predictor of recurrence than the tumor ...

journal_title：Neoplasma

authors： Komorowski AL,Hsu CC,Julka KD,Vasavada B,Lin CC,Wang CC,Chen CL

更新日期：2018-03-14 00:00:00

abstract：:Factors influencing circulating miRNA as a diagnostic marker of hepatocellular carcinoma (HCC) are still unknown. We used two kits to extract total RNA of 90 paired serum and plasma samples of volunteers in different statuses including healthy, hepatitis, cirrhosis and HCC. U6, miR-183 and cel-miR-39 expression levels...

journal_title：Neoplasma

authors： Wang Y,Liang Z,Gao Y,Zhai D,Rao Q,Shi W,Yang B,Jing L,Guo H,Liu T,Liu J,DU Z

更新日期：2015-01-01 00:00:00

abstract：:It is hypothesized that "cancer stem cells" are responsible for the resistance to chemotherapy of cancer cells in ovarian cancers. The objective of the studies was to explore if the stem cell biomarkers could be used to predict the tumor chemotherapy-resistance in serous ovarian cancer patients. Expression of two puta...

journal_title：Neoplasma

authors： Qin Q,Sun Y,Fei M,Zhang J,Jia Y,Gu M,Xia R,Chen S,Deng A

更新日期：2012-01-01 00:00:00

abstract：:The histochemical properties of mucus in 48 diffuse type gastric carcinomas and in 46 intestinal type gastric cancers were investigated. In the diffuse type there was a prevalence of intracellular secretion of mucopolysaccharides with a significantly larger portion of sulfated mucopolysaccharides. Acid mucopolysacchar...

journal_title：Neoplasma

authors： Tichá V,Jansa P,Tichý M

更新日期：1988-01-01 00:00:00

abstract：:Overexpressed Wilms tumor gene 1 (WT1) has been found in a majority of patients with acute myeloid leukemia (AML). The aim of this study was to confirm the applicability of WT1 expression measurement as a marker of minimal residual disease (MRD). The expression of WT1 gene was measured by real-time polymerase chain re...

journal_title：Neoplasma

authors： Polak J,Hajkova H,Haskovec C,Cechova H,Marinov I,Mikulenkova D,Markova J,Markova M,Vitek A,Valkova V

更新日期：2013-01-01 00:00:00

abstract：:A comparison of efficacies of medroxyprogesterone acetate (MPA) and the antiestrogen tamoxifen (TX) in the therapy for advanced breast cancer in patients who had already previously been intensely treated showed that, as to the objective remissions, the two drugs can be looked upon as equivalent. Nevertheless, with MPA...

journal_title：Neoplasma

authors： Lorenz I,Mechl Z

更新日期：1985-01-01 00:00:00

abstract：:Some selected data on cancer statistics in the USSR and results of the nationwide cancer screening activities are presented. The usefullness of some new methods in prophylactic examination is discussed. ...

journal_title：Neoplasma

authors： Alexandrov NN

更新日期：1975-01-01 00:00:00

abstract：UNLABELLED:The current study aimed to evaluate the efficacy of sorafenib-based combined therapy against hepatocellular carcinoma (HCC). HepG2 cells were exposed to sorafenib, irinotecan, and oxaliplatin and then subjected to MTT assay to determine chemosensitivity. Flow cytometry was used to examine cell cycle distribu...

journal_title：Neoplasma

authors： Wang Z,Zhao Z,Wu T,Song L,Zhang Y

更新日期：2015-01-01 00:00:00

abstract：:Serum levels of seven specific proteins mostly acute phase reactants (APR) have been studied (transferrin, alpha 2-macroglobulin, alpha 1-antitrypsin, haptoglobin, C3, ceruloplasmin, orosomucoid) in 14 healthy subjects and in 55 patients with multiple myeloma. The alpha 2-macroglobulin and transferrin are significantl...

journal_title：Neoplasma

authors： San Miguel J,Vicente V,Battle J,Hernandez F,Lopez Borrasca A

更新日期：1981-01-01 00:00:00

abstract：:Multiple myeloma (MM) is a hematological malignancy caused by clonal proliferation of malignant plasma cells (PC). The aim of the work is to determine prognostic significance of morphological subtypes of PC in relation to overall treatment response, long-term survival and other conventional prognostic parameters. One ...

journal_title：Neoplasma

authors： Al-Sahmani M,Trnavska I,Sevcikova S,Antosova M,Antosova L,Kissova J,Adam Z,Pour L,Nemec P,Greslikova H,Krejci M,Zahradova L,Bulikova A,Penka M,Hajek R

更新日期：2011-01-01 00:00:00

abstract：:Olfactomedin 4 (OLFM4) is a member of olfactomedin domain-containing protein family. Human OLFM4 is preferentially expressed in the gastrointestinal tract (stomach, small intestine and colon), prostate, and bone marrow. Recent studies demonstrate that OLFM4 is involved in the establishment and/or development of some t...

journal_title：Neoplasma

authors： Yu L,Wang L,Chen S

更新日期：2011-01-01 00:00:00

abstract：:The authors have studied the influence of primary, methylcholanthrene-induced tumor on T and B lymphocytes of spleen, thymus, draining lymph nodes and peripheral blood of rats. Differences in weight of tumors were found to correlate with changes in proportionality of T and B lymphocytes of followed organs. Small tumor...

journal_title：Neoplasma

authors： Klobusická M,Kalafut F,Novotná L

更新日期：1978-01-01 00:00:00

abstract：:Human leukocyte antigen - G (HLA-G) is a non-classical HLA class I antigen with restricted distribution in normal tissues. Ectopic HLA-G expression observed at some pathological circumstances as malignant transformation might be triggered by epigenetic modifications such as DNA demethylation. Recently it was demonstra...

journal_title：Neoplasma

authors： Polakova K,Bandzuchova E,Sabty FA,Mistrik M,Demitrovicova L,Russ G

更新日期：2009-01-01 00:00:00

abstract：:Few studies to date have reported on the development and application of a nanobiosensor based on localized surface plasmon resonance (LSPR) for detecting gene mutations. This study aimed to develop a novel LSPR biosensor used for detecting p53 mutation. Nanosphere lithography was used to fabricate the silver nanoparti...

journal_title：Neoplasma

authors： Duan RQ,Yuan JL,Yang H,Luo XG,Xi MR

更新日期：2012-01-01 00:00:00

abstract：:Up to 19--20 fractions of separate RNA species and groups have been revealed in malignant tumors of the stomach and mucous membrane of patients with stomach cancer, ulcer and polyposis of the stomach by means of the method of analytical and preparative electrophoresis in 2.5% polyacrylamide gel. A more intensive incor...

journal_title：Neoplasma

authors： Seitz JF,Kalinvosky VP

更新日期：1976-01-01 00:00:00

abstract：:Cytogenetic studies in Chinese hamster ovary (CHO) cells using aqueous and organic extracts of pan masalas, as well as genomic damage observed among pan masala consumers have conclusively shown genotoxic potential of pan masala-a dry complex mixture of areca nut, lime, catechu, cardamom, unspecified flavoring agent, e...

journal_title：Neoplasma

authors： Patel RK,Trivedi AH,Jaju RJ,Kukreti MS,Bhatavdekar JM,Shah PM,Patel DD

更新日期：1998-01-01 00:00:00

abstract：:The goal of this study is to examine whether vitamin D receptor (VDR) polymorphisms are associated with the susceptibility to breast cancer. Meta-analysis was employed to investigate the association between the VDR FokI, BsmI, ApaI, and TaqI polymorphisms and the incidence of breast cancer.A total of 32 comparative st...

journal_title：Neoplasma

authors： Lee YH,Song GG

更新日期：2014-01-01 00:00:00

abstract：:The present study was carried out to investigate the synergistic apoptotic potential of arabinoxylan rice bran (MGN-3/Biobran) and curcumin (turmeric) on human multiple myeloma (MM) cell line U266 , in vitro. U266 cells were cultured with MGN-3 (50 or 100μg/ml) and curcumin (2.5-10μM) for 3 days. The effects of MGN-3 ...

journal_title：Neoplasma

authors： Ghoneum M,Gollapudi S

更新日期：2011-01-01 00:00:00

abstract：:The results from our investigations concerning the secretory activity of interleukin 10 (IL-10) by two transplantable melanoma cells showed that a spontaneous alteration of the native-melanotic line into an amelanotic form and the tumor progression connected with it, were accompanied by a 6-fold decrease of the IL-10 ...

journal_title：Neoplasma

authors： Kozłowska K,Zarzeczna M,Cichorek M,Wójcik S

更新日期：2003-01-01 00:00:00

abstract：:The results of treatment of acute promyelocytic leukemia, when combination ATRA + chemotherapy is used in induction and maintainance therapy and risk adapted strategy applied in consolidation, improved at present time. Enhanced supportive therapy also contribute to improved outcome of APL patients. 3 - year relapse fr...

journal_title：Neoplasma

authors： Oravcova I,Czako B,Demeckova E,Demitrovicova L,Greksak R,Kotoucek P,Mego M,Mikuskova E,Richterova K,Al Sabti F,Mistrik M

更新日期：2010-01-01 00:00:00

abstract：:Presented study aimed to prepare A10 aptamer-modified poly (D,L-lactic-co-glycolic acid) (PLGA) nanoparticles loaded with triplex forming oligonucleotides(TFO) for targeted prostate cancer therapy. We first synthesized a PLGA-PEG-Apt copolymer. The PLGA-PEG-Apt nanoparticles (NP-Apt) were loaded with TFO using double ...

journal_title：Neoplasma

authors： Jiao J,Zou Q,Zou MH,Guo RM,Zhu S,Zhang Y

更新日期：2016-01-01 00:00:00

abstract：:Occurrence of uveal metastases is higher, than the number of clinically diagnosed cases, furthermore all cases are not amenable to therapy. Treatment of primary cancer is permanently improving, as a result life prospective is better, with an increasing number of late distant metastases in an unusual location, as e.g. ...

journal_title：Neoplasma

authors： Bajcsay A,Kontra G,Récsán Z,Tóth J,Fodor J

更新日期：2003-01-01 00:00:00

abstract：:Using the model of Sarcoma I (SaI) (H-2a) tumor allograft transplanted to normal B10 (H-2b) mice and to B10 mice pretreated with ATS, we studied the effects of anti-Thy-1,2 monoclonal antibody (MTA) and compared them with those of rabbit polyvalent antiserum against mouse thymocytes (ATS). When administered shortly be...

journal_title：Neoplasma

authors： Sobotková E,Sůla K,Nouza K

更新日期：1988-01-01 00:00:00

abstract：:To date, epidemiological studies have assessed the association between Toll-like receptor 2 (TLR2) gene polymorphisms and cancer risk. However, the results of these studies remain controversial. We aimed to examine the associations between three SNPs (Delta22, rs3804099 and rs3804100) of TLR2 gene and cancer risk by c...

journal_title：Neoplasma

authors： Wang X,Li J,Xie W,Zhang W,Chang Y

更新日期：2013-01-01 00:00:00

abstract：:In this work we tried to estimate the role of mitochondria in the ability of cells of two: melanotic and amelanotic transplantable melanoma lines to undergo spontaneous and camptothecin-induced apoptosis. We measured mitochondrial transmembrane potential (DeltaPsi) changes during culture without (spontaneous apoptosis...

journal_title：Neoplasma

authors： Cichorek M,Kozłowska K,Bryl E

更新日期：2007-01-01 00:00:00

abstract：:Although the candidemia still remains a serious health problem, the study of candidemia in cancer patients is limited. We conducted a retrospective analysis of candidemia among 31 adult patients hospitalized in one oncological center. The mean annual incidence of candidemia was 0.14±0.05/1000 patient-days (range 0.04-...

journal_title：Neoplasma

authors： Szymankiewicz M,Nowikiewicz T

更新日期：2020-11-01 00:00:00

abstract：:Heat Shock proteins 70 (Hsp70) is a family of highly conserved molecules that maintain the function of crucial cellular pathways during stress. Hsp70 derived from tumor cells is bound with tumor antigenic peptides from the diverse antigen cytosolic pool. Tumor-derived Hsp70 preparations after ex vivo administration pe...

journal_title：Neoplasma

authors： Kumar S,Deepak P,Acharya A

更新日期：2009-01-01 00:00:00

abstract：:To evaluate the diagnostic usefulness of simultaneous determinations of carcinoembryonic antigen (CEA), neuron specific enolase (NSE), chorionic gonadotrophin (HCG) and carbohydrate antigenic determinant 19-9 (CA 19-9), we studied 48 patients with small cell lung carcinoma (SCLC) and 15 with nonmalignant lung disease....

journal_title：Neoplasma

authors： Nikliński J,Chyczewska E,Furman M,Kowal E,Laudanski J,Chyczewski L

更新日期：1993-01-01 00:00:00

abstract：:The neuroleptics, well known as stimulants of prolactin release, are supposed to increase breast cancer incidence. To verify this hypothesis, we selected a group of 853 deaths of female inpatients with mental diseases recorded in the Dr. G. Marinescu Hospital between 1929 and 1978. Using proportionally and indirect st...

journal_title：Neoplasma

authors： Costa D,Mesteş E,Coban A

更新日期：1981-01-01 00:00:00

abstract：:Bladder cancer remains a very challenging disease to treat with the high rates of recurrence and progression associated with current therapies. Although the association between bladder cancer pathology and circRNAs remains undetermined, circRNAs signatures may be useful as prognostic and predictive factors and clinica...

journal_title：Neoplasma

authors： Liu L,Wu SQ,Zhu X,Xu R,Ai K,Zhang L,Zhao XK

更新日期：2019-06-03 00:00:00