Analysis of ceRNA network identifies prognostic circRNA biomarkers in bladder cancer.

abstract：:Hepatocellular carcinoma is the most common primary malignancy of the liver. The chemotherapeutic drug cisplatin is widely used for advanced liver cancer. However, the development of cisplatin resistance in cancer cells, which is related with the decreased cellular susceptibility to apoptosis, results in a major limit...

journal_title：Neoplasma

authors： Zhang B,Cao K,Liu Z,Shan W,Wen Q,Wang R

更新日期：2019-05-11 00:00:00

abstract：:Leucine-rich repeat-containing G protein-coupled receptor 5(LGR5) was identified as the stem cell marker of colon cancer stem cells(CSCs),which were considered as the main criminal cells initiation and reinitiation of colon cancer. We intended to demonstrate and further explain the relationship between LGR5 and colon ...

journal_title：Neoplasma

authors： Liu Z,Dai W,Jiang L,Cheng Y

更新日期：2014-01-01 00:00:00

abstract：:PMP22 is recently recognized as a key player in a variety of prevalent cancers. In this study, we sought to explore the correlation of peripheral myelin protein 22 (PMP22) expression with cell proliferation, invasion and apoptosis in lung cancer cell line. miR29 was transfected into Anip973 lung adenocarcinoma cell li...

journal_title：Neoplasma

authors： Qu H,Zhu M,Tao Y,Zhao Y

更新日期：2015-01-01 00:00:00

abstract：:KLF6 is a key cell cycle regulator that is downregulated in several kinds of human cancers, including gastric cancer. The IVS1 -27G/A polymorphism of KLF6 has been investigated, which can influence susceptibility to gastric cancer and disease outcome. In order to investigate whether the IVS1 -27G/A polymorphism of KLF...

journal_title：Neoplasma

authors： Cho YG,Lee HS,Song JH,Kim CJ,Park YK,Nam SW,Yoo NJ,Lee JY,Park WS

更新日期：2008-01-01 00:00:00

abstract：:It is generally believed that the existence of cancer stem cells (CSCs) is related to tumor recurrence and metastasis of hepatocellular carcinoma (HCC). Neuropilin1 (NRP1) is involved in numerous pathophysiological processes of tumor progression, however, whether NRP1 is involved in the regulation of liver CSCs and me...

journal_title：Neoplasma

authors： Li X,Zhou Y,Hu J,Bai Z,Meng W,Zhang L,Song X,Wei Y,Yan J,Zhou Y

更新日期：2020-12-23 00:00:00

abstract：:Cytolytic activity of mineral oil elicited rat peritoneal macrophages activated by lipopolysaccharide (LPS) and/or rIFN-gamma, rIL-2, Zymosan and PMA (4-beta-phorbol-12-beta-myristate 13-alpha-acetate) was detected in the presence of various concentrations of L-arginine. This paralleled the NO2- production in the pres...

journal_title：Neoplasma

authors： Kusenda J,Kalafut F,Klobusická M,Novotná L

更新日期：1992-01-01 00:00:00

abstract：:Protein p53 is the tumor suppressor involved in cell cycle control and apoptosis. As a transcription factor p53 controls many cell processes and helps in prevention of cancer development. The p53 gene is polymorphic. Polymorphisms can affect the important regions involved in protein tumor suppressor activity. The well...

journal_title：Neoplasma

authors： Franeková M,Zúbor P,Stanclová A,Dussan CA,Bohusová T,Galo S,Dobrota D,Kajo K,Péc M,Racay P

更新日期：2007-01-01 00:00:00

abstract：:A capture monoclonal antibody-based assay has been established for detecting the p24 core protein and the gp51 envelope glycoprotein of bovine leukemia virus (BLV). This assay is rapid, highly sensitive and specific. Viral antigens in test samples were identified using mouse monoclonal antibody-coated or microtiter pl...

journal_title：Neoplasma

authors： Bán J,Altanerová V,Orlík O,Altaner C

更新日期：1991-01-01 00:00:00

abstract：:Helicase POLQ-like (HELQ), an ATP-dependent 3'-5' DNA helicase, plays pivotal roles in DNA processing, such as DNA replication, recombination and repair. The recent discovery of HELQ in mouse model and human cancer cell reveal that genetic alteration of HELQ is involved in cancer susceptibility and subfertility. Here ...

journal_title：Neoplasma

authors： Han X,Zhao L,Li X

更新日期：2016-01-01 00:00:00

abstract：:High-dose chemotherapy (HDC) in high-risk breast cancer is one of the possible approaches how to improve therapeutic results, eventually, to overcome the incurability of the disease. In recent randomized studies superiority of HDC to conventional therapy has not been unambiguously established. Nevertheless, many oncol...

journal_title：Neoplasma

authors： Filip S,Petera J,Odrázka K,Bláha M

更新日期：2000-01-01 00:00:00

abstract：:Melanoma is a malignant tumor. The acquisition of stemness of melanoma cells aggravates the malignant transformation, which can be regulated by microRNAs (miRNAs, miR). MiR-363-3p is a key tumor-related miRNA, but its role in stemness and melanoma cells is still unknown. Presently, miR-363-3p, induced by hypoxia induc...

journal_title：Neoplasma

authors： Hao T,Li CX,Ding XY,Xing XJ

更新日期：2019-05-23 00:00:00

abstract：:During the years 1973-1987, 75 patients were irradiated for brain metastases of unknown origin at the Institute of Oncology in Ljubljana. Of these, 35 (47%) were previously treated by surgery: Metastases were completely removed in 22 patients and partially in 7, whereas biopsy alone was performed in 6 patients. Based ...

journal_title：Neoplasma

authors： Debevec M

更新日期：1990-01-01 00:00:00

abstract：:Serial cytogenetic characteristics of four lymphoblastoid cell lines derived from the peripheral blood of four patients with acute leukemia are presented, including G and C banding techniques and the analysis of sister chromatid exchanges by means of FPG technique. One of these lines turned into predominantly diploid ...

journal_title：Neoplasma

authors： Michalová K,Málková J,Cinátl J,Placerová J

更新日期：1977-01-01 00:00:00

abstract：:The aim of our study was to correlate the serum concentration of human epididymis protein 4 (HE4) in lung cancer patients with the bone metastases detected by whole-body bone scintigraphy. The serum concentrations of HE4 were determined by electrochemiluminescence immunoassay method in 60 patients with lung cancer and...

journal_title：Neoplasma

authors： Weissensteiner J,Babusikova E

更新日期：2019-06-29 00:00:00

abstract：:Patients with clinically node-positive bladder cancer have a poor prognosis, with many receiving only palliative chemo- therapy. We evaluated oncological results in bladder cancer patients with clinically regional and supraregional lymph- adenopathy treated with induction chemotherapy (IC) and consolidative cystectomy...

journal_title：Neoplasma

authors： Stanik M,Poprach A,Macik D,Capak I,Maluskova D,Mareckova N,Lakomy R,Jarkovsky J,Dolezel J

更新日期：2018-01-01 00:00:00

abstract：:Optimal conditions were determined for the distribution of Ehrlich ascites carcinoma (EAC) and L-5178Y mouse tumor cells, proliferating in vivo, by their age within the cell cycle by sedimentation in a buffered linear sacharose density gradient. Measurements of cell size, DNA content and incorporation of tritiated thy...

journal_title：Neoplasma

authors： Horáková K,Fusková A,Ceglédyová N

更新日期：1976-01-01 00:00:00

abstract：:In transplanted mice, the P388 tumor grew better in castrated than in non castrated (NC) mice. The proportion of CD8+ in the blood was more numerous in NC mice. The T cell subsets (CD4+ and CD8+) were also high in the mice with small tumor tissue (<10 mg). The correlation observed between the tumor weight and T cell s...

journal_title：Neoplasma

authors： Aboudkhil S,Henry L,Zaid A,Bureau JP

更新日期：2005-01-01 00:00:00

abstract：:In comparison with the 7th Edition, the 8th Edition of the American Joint Committee on Cancer (AJCC) staging system no longer considers the mitotic count in the a or b T1 categorization for melanoma, but it adopts a sub-stratification based on the Breslow's depth. Today, the death burden of thin melanoma is still seve...

journal_title：Neoplasma

authors： Roncati L,Piscioli F

更新日期：2018-09-19 00:00:00

abstract：:Expression of microRNA-129-5p (miR-129-5p) has been reported to decrease in gastric cancer (GC). However, little information is available about how miR-129-5p affects cell migration and invasion of GC. Cancer samples and matched non-tumor adjacent tissues were obtained from patients with GC. Besides, peripheral blood ...

journal_title：Neoplasma

authors： Jiang Z,Wang H,Li Y,Hou Z,Ma N,Chen W,Zong Z,Chen S

更新日期：2016-01-01 00:00:00

abstract：UNLABELLED:The study was aimed at detecting the expression of a newly found oncogene, astrocyte elevated gene-1 (AEG-1), in renal cell carcinoma (RCC) and its correlation with histopathologic features and the survival of patients. Real-time reverse transcription-PCR and Western blot showed markedly higher expression of...

journal_title：Neoplasma

authors： Chen W,Ke Z,Shi H,Yang S,Wang L

更新日期：2010-01-01 00:00:00

abstract：:Serological analysis of human membrane antigens have been performed using rabbit xenosera against membrane fraction obtained from different cells (B cell lines: RAJI, RAMOS, DAUDI, UHKT-2: T cell line: MOLT-3, as well as normal pooled lymphocytes). The direct cytotoxicity testing demonstrated that xenogeneic rabbit B ...

journal_title：Neoplasma

authors： Koubek K

更新日期：1983-01-01 00:00:00

abstract：:The work is aimed at the occurrence of secondary malignancies after therapy for primary testicular tumors. The target of the work was determination of the number and type of secondary tumors, their effect on the survival and comparison of relative risk of the origination of secondary tumors depending on particular tre...

journal_title：Neoplasma

authors： Siffnerova H,Kralova D

更新日期：2007-01-01 00:00:00

abstract：:Family history of colorectal cancer is recognized as a risk factor for the disease and the development of colorectal cancer represents a suitable model for illustrating multistep tumor development. Bleomycin induced chromosome sensitivity studies were done in 7 colorectal cancer families consisting of 12 colorectal ca...

journal_title：Neoplasma

authors： Jyothish B,Ankathil R,Chandini R,Vinodkumar B,Nayar GS,Roy DD,Madhavan J,Nair MK

更新日期：1997-01-01 00:00:00

abstract：:The treatment of locally advanced head and neck cancer (LAHNC) requires a multimodality approach. Radiotherapy with combination of chemotherapy are demonstrated to be effective, however, the treatment intensification leads to increased toxicity at the same time. The implementation of three-dimensional conformal radiot...

journal_title：Neoplasma

authors： Jirkovska M,Novak T,Malinova B,Lohynska R

更新日期：2019-06-19 00:00:00

abstract：:There is some evidence that prostaglandin (PGE)-secreting cells may have a role in immunosuppression in cancer patients. In this work we investigated the effects of indomethacin--a PGE synthesis inhibitor, on PHA-induced lymphoproliferative response in vitro. Twenty patients with lung cancer before therapy were includ...

journal_title：Neoplasma

authors： Stanojević-Bakić N,Vucković-Dekić L,Susnjar S,Spuzić I

更新日期：1992-01-01 00:00:00

abstract：:The serum concentrations of immunosuppressive acidic protein (IAP), CA 125, alpha-1-antitrypsin (AL-1-AT), C-reactive protein (CRP) and ceruloplasmin (COP) were determined in 63 patients with ovarian carcinoma (mean age 56.9 +/- 11.1 years). The threshold value of IAP was 640 micrograms/ml (means + 2SD), of CA 125 35 ...

journal_title：Neoplasma

authors： Koebl H,Tatra G,Bieglmayer C

更新日期：1988-01-01 00:00:00

abstract：:This study comprises 46 patients with various stages of breast carcinoma and 49 normal women as control group. Serum xanthine oxidase and uric acid levels were determined. Assessment in terms of changes of the enzyme xanthine oxidase was carried out prior and after surgery as a short term follow up. There was a signif...

journal_title：Neoplasma

authors： Alsabti E

更新日期：1980-01-01 00:00:00

abstract：:The goal of this study is to examine whether vitamin D receptor (VDR) polymorphisms are associated with the susceptibility to breast cancer. Meta-analysis was employed to investigate the association between the VDR FokI, BsmI, ApaI, and TaqI polymorphisms and the incidence of breast cancer.A total of 32 comparative st...

journal_title：Neoplasma

authors： Lee YH,Song GG

更新日期：2014-01-01 00:00:00

abstract：:The distribution of peanut agglutinin (PNA) receptors, nonspecific cross-reacting antigen (NCA) molecule and 3-fucosyl-N-acetyllactosamine (FAL) in myeloid leukemic cells isolated by density gradient centrifugation was compared using immunofluorescence test (IF). Patients with acute myelocytic leukemias (AML) type M2 ...

journal_title：Neoplasma

authors： Noworolska A,Slesak B,Harłonzińska A,Richter R

更新日期：1991-01-01 00:00:00

abstract：:The oral cavity is continually exposed to various traumas due to the effect of thermal, mechanical and chemical stimuli, which when accompanied by inflammatory states may promote the growth of neoplastic changes. Numerous studies have revealed a correlation between the expression of p53 and Bcl-2 proteins and the prog...

journal_title：Neoplasma

authors： Sulkowska M,Famulski W,Chyczewski L,Sulkowski S

更新日期：2001-01-01 00:00:00