Estrogen-withdrawal migraine. I. Duration of exposure required and attempted prophylaxis by premenstrual estrogen administration.

Abstract:

:The minimum exposure to estrogen required to cause estrogen-withdrawal migraine has been studied by giving long-acting estradiol valerate to four women and short-acting estradiol benzoate to two women. It was found that several days of exposure to high estrogen levels were needed to cause migraine on estrogen withdrawal. Oral administration of estrogen supplements in the form of estradiol valerate or as conjugated equine estrogens during the premenstrual phase in four women did not significantly affect plasma levels of estradiol, nor was it effective in preventing menstrual migraine.

journal_name

Neurology

journal_title

Neurology

authors

Somerville BW

doi

10.1212/wnl.25.3.239

subject

Has Abstract

pub_date

1975-03-01 00:00:00

pages

239-44

issue

3

eissn

0028-3878

issn

1526-632X

journal_volume

25

pub_type

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