Blast-like cells in the cerebrospinal fluid of young infants: further characterization of clinical setting, morphology and origin.

Abstract:

:Blast-like cells in the cerebrospinal fluid (CSF) of neonates have been identified and previously suggested to be of germinal matrix origin. Twelve additional CSF specimens with blast-like cells collected at the University of Texas Medical Branch, Galveston, between 1985-1992 were analyzed. The cytological features of the blast-like cells as well as their associated clinical setting were further characterized by the authors. All patients in the study were young infants with hydrocephalus and nearly all underwent placement of a ventriculoperitoneal (VP) shunt at the time the CSF specimen was collected. In addition, a cytologic preparation of germinal matrix cells obtained from an autopsy specimen was analyzed, which closely resembled the blast-like cells. These data provide additional evidence that blast-like cells originate from the germinal matrix.

journal_name

Am J Clin Pathol

authors

Jaffey PB,Varma SK,DeMay RM,McLucas EJ,Campbell GA

doi

10.1093/ajcp/105.5.544

subject

Has Abstract

pub_date

1996-05-01 00:00:00

pages

544-7

issue

5

eissn

0002-9173

issn

1943-7722

journal_volume

105

pub_type

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