Different osteochondral potential of clonal cell lines derived from adult human trabecular bone.

abstract：:Approximately 40 to 50 infants and children with similar epidemiologic, clinical, and laboratory features of AIDS have been described. The occurrence of significant numbers of patients with PAIDS in geographic areas that are associated with similar risk factors and clinical features of AIDS suggests a common cause. Im...

journal_title：Annals of the New York Academy of Sciences

authors： Ammann AJ,Wara DW,Cowan MJ

更新日期：1984-01-01 00:00:00

abstract：:We have created genetically altered mice to investigate how expression of the Na(+)-Ca(2+) exchange protein alters excitation-contraction (E-C) coupling. Whereas low levels of exchanger overexpression have minimal effects on E-C coupling properties, high levels of overexpression in homozygous animals results in suscep...

journal_title：Annals of the New York Academy of Sciences

authors： Goldhaber JI,Henderson SA,Reuter H,Pott C,Philipson KD

更新日期：2005-06-01 00:00:00

abstract：:This brief review is designed to highlight the limitations of our knowledge given the difficulties in simulating the in vivo condition in models established in vitro and ex vivo. Despite this uncertainty, mounting evidence indicates that the GPIIb-IIIa receptor mediates crucial platelet functions and that control over...

journal_title：Annals of the New York Academy of Sciences

authors： Coller BS

更新日期：1987-01-01 00:00:00

abstract：:Clumps of corona cells were separated from oocytes at the moment of fertilization control and were subsequently processed and cut into 1-mu sections to study their general morphologic patterns. This study revealed an extensive phagocytosis of spermatozoa by corona cells. Clumps of mural granulosa cells of comparable s...

journal_title：Annals of the New York Academy of Sciences

authors： Pijnenborg R,Gordts S,Ongkowidjojo R,Brosens I

更新日期：1985-01-01 00:00:00

abstract：:Na+/Ca2+-K+ exchangers (NCKX) are plasma membrane transporters that are thought to mainly mediate Ca2+ extrusion (along with K+) at the expense of the Na+ electrochemical gradient. However, because they are bidirectional, most assays have relied on measuring their activity in the reverse (Ca2+ import) mode. Herein we ...

journal_title：Annals of the New York Academy of Sciences

authors： Altimimi HF,Schnetkamp PP

更新日期：2007-03-01 00:00:00

abstract：:Autoimmune diseases include a diverse group of over 80 conditions. Sjögren's syndrome is the second most common autoimmune rheumatic disease, with an estimated prevalence in the United States of 2-4 million persons. There are prominent and consistent oral and dental findings in Sjögren's syndrome related to the autoim...

journal_title：Annals of the New York Academy of Sciences

authors： Fox PC

更新日期：2007-03-01 00:00:00

abstract：:Bisphosphonates are widely used in the management of metastatic disease to bone and in diseases of altered bone turnover. Recently, multiple-case series and retrospective studies have established a relationship between necrotic bone lesions localized to the jaw and the use of chronic bisphosphonate therapy. This condi...

journal_title：Annals of the New York Academy of Sciences

authors： Ruggiero SL

更新日期：2011-02-01 00:00:00

abstract：:Nitric oxide (NO) has been implicated as a mediator of vasodilation and neurotransmission in the mammalian cochlea. This is demonstrated by the presence of nitric oxide synthase (NOS) and nitric oxide (NO) in the blood vessels and the organ of Corti in the cochlea. It is not certain if the neurons in the spiral gangli...

journal_title：Annals of the New York Academy of Sciences

authors： Ruan RS

更新日期：2002-05-01 00:00:00

abstract：:Sarcopenia is the involuntary loss of skeletal muscle mass and strength that occurs with aging, resulting in physical frailty. One potential explanation for sarcopenia is the failure of muscle to regenerate after damage, some of which may be due to changes in the function of satellite cells. Recent studies have identi...

journal_title：Annals of the New York Academy of Sciences

authors： Machida S,Narusawa M

更新日期：2006-05-01 00:00:00

abstract：:The human serum resistance-associated (SRA) gene was identified in 28 (80%) of the 35 T.b. rhodesiense trypanosomes from parasitologically confirmed sleeping sickness cases, using the primers designed by Radwanska and in 27 (77.1%) of the same 35 T.b. rhodesiense trypanosomes using the primers designed by Gibson. Howe...

journal_title：Annals of the New York Academy of Sciences

authors： Enyaru JC,Matovu E,Nerima B,Akol M,Sebikali C

更新日期：2006-10-01 00:00:00

abstract：:Clinical trials for ischemic stroke have been characterized by a disappointing series of negative results, using a panoply of pharmacologic agents. This paper emphasizes five physiologic measures that can be taken to mitigate ischemic brain damage. These are (1) hypothermia, (2) insulin, (3) arterial hyperoxemia, (4) ...

journal_title：Annals of the New York Academy of Sciences

authors： Auer RN

更新日期：2001-06-01 00:00:00

abstract：:We have heard a wide-ranging set of talks on cosmology and high energy astrophysics at this conference. All I can really do in this short talk is to present my subjective impression of an arbitrary selection of highlights. ...

journal_title：Annals of the New York Academy of Sciences

authors： Rees MJ

更新日期：1993-06-01 00:00:00

abstract：:Deregulation of signaling pathways is a common feature observed in human cancers and other diseases. Therefore, there is a strong need for compounds that are able to modulate or inactivate upregulated signaling events. Natural compounds extracted from plants have long been used and still present a dynamic domain in th...

journal_title：Annals of the New York Academy of Sciences

authors： Blasius R,Dicato M,Diederich M

更新日期：2007-01-01 00:00:00

abstract：:In humans any effects of dietary saturated fats or omega-6 polyunsaturates on blood pressure appear to be mediated by changes in caloric intake and long-term weight changes. In contrast, omega-3 fatty acids have a mild antihypertensive effect which is seen most clearly in untreated subjects with higher blood pressures...

journal_title：Annals of the New York Academy of Sciences

authors： Beilin LJ

更新日期：1993-06-14 00:00:00

abstract：:Primary hyperparathyroidism (PHPT) results from excessive secretion of parathyroid hormone (PTH), and catabolic and anabolic effects of PTH on bone may lead to overall deleterious effects on skeleton. The aim of this study was to analyze the changes in lumbar spine bone mineral density (BMD) in patients with PHPT who ...

journal_title：Annals of the New York Academy of Sciences

authors： Lumachi F,Camozzi V,Ermani M,Nardi A,Luisetto G

更新日期：2007-11-01 00:00:00

abstract：:The orbital evolution of about 26,000 Jupiter-crossing objects and 1,500 resonant asteroids under the gravitational influence of planets was investigated. The rate of their collisions with terrestrial planets was estimated by computing the probabilities of collisions based on random-phase approximations and the orbita...

journal_title：Annals of the New York Academy of Sciences

authors： Ipatov SI,Mather JC

更新日期：2004-05-01 00:00:00

abstract：:Organophosphorus pesticides (OPs) and nerve agents (NAs) are highly toxic chemicals that pose a significant threat to human health worldwide. These compounds induce status epilepticus (SE) by irreversibly blocking the ability of acetylcholinesterase to break down acetylcholine at neural synapses. Animal models of orga...

journal_title：Annals of the New York Academy of Sciences

authors： McCarren HS,McDonough JH Jr

更新日期：2016-06-01 00:00:00

abstract：:Platelets play important roles for hemostasis with activated platelets adhering to the injured vessel wall to initiate platelet aggregation. At the same time, our study revealed the cytotoxic effect on endothelial cells characterized by an increase of intracellular Ca++ and a decrease of EDRF production, which may cau...

journal_title：Annals of the New York Academy of Sciences

authors： Numano F,Kishi Y,Ashikaga T,Hata A,Makita T,Watanabe R

更新日期：1995-01-17 00:00:00

abstract：:Alternative splicing of RNA transcripts is a general characteristic for NCX genes in mammals, mollusks, and arthropods. Among the family of three NCX genes in mammals, the NCX1 gene contains six exons, namely, A, B, C, D, E, and F, that make up the alternatively spliced region. Studies of the NCX1 gene transcripts sug...

journal_title：Annals of the New York Academy of Sciences

authors： Schulze DH,Polumuri SK,Gille T,Ruknudin A

更新日期：2002-11-01 00:00:00

abstract：:Tocopherols are known to undergo metabolism to phytyl chain-shortened metabolites excreted in urine. We sought to characterize the pathway, including associated enzymes, involved in this biotransformation. We previously found that human hepatoblastoma (HepG2) cultures metabolized tocopherols to their corresponding sho...

journal_title：Annals of the New York Academy of Sciences

authors： Parker RS,Sontag TJ,Swanson JE,McCormick CC

更新日期：2004-12-01 00:00:00

abstract：:At least twenty-two architectonic areas can be distinguished within the orbital and medial prefrontal cortex (OMPFC). Although each of these areas has a distinct structure and connections, they can be grouped into two "networks," defined by cortico-cortical connections that primarily interconnect areas within each net...

journal_title：Annals of the New York Academy of Sciences

authors： Price JL

更新日期：1999-06-29 00:00:00

abstract：:Frontal lobe functions include a range of cognitive, emotional, and social abilities that enable goal-directed behavior. Although a number of studies have plotted the development of frontal lobe functions in childhood, few have extended into the adolescent years. There is also little information on which cognitive and...

journal_title：Annals of the New York Academy of Sciences

authors： Rosso IM,Young AD,Femia LA,Yurgelun-Todd DA

更新日期：2004-06-01 00:00:00

abstract：:Nanofluids consisting of nanometer-sized particles dispersed in base liquids are known to be effective in extending the saturated boiling regime and critical heat flux in pool boiling. The heat transfer characteristics of nanosilica suspensions with particle sizes of 10 and 20 nm in pool boiling with a suspended heati...

journal_title：Annals of the New York Academy of Sciences

authors： Kumar R,Milanova D

更新日期：2009-04-01 00:00:00

abstract：:In this historical treatise two biological-system theories, formulated in the 1920s and 1930s, are roughly sketched. The first part discusses the concept of a thermodynamically open system, as coined by the Russian pathologist Ervin Bauer (1890-1942). Like Bertalanffy, Bauer wanted to prove the specificity of the biol...

journal_title：Annals of the New York Academy of Sciences

authors： Brauckmann S

更新日期：2000-01-01 00:00:00

abstract：:Language and music are human universals involving perceptually discrete elements organized in hierarchically structured sequences. The set of principles governing the combination of these structural elements into sequences is known as syntax. A violation of expectancies concerning syntactic regularities may be reflect...

journal_title：Annals of the New York Academy of Sciences

authors： Jentschke S,Koelsch S,Friederici AD

更新日期：2005-12-01 00:00:00

abstract：:The use of animal cells, tissues, or organs for humans is being investigated as an alternative to allotransplantation and as therapy for a broad range of disease states including diabetes, Parkinson's disease, and neurologic pain control. The risk of transmitting novel infections with these tissues, xenozoonoses, has ...

journal_title：Annals of the New York Academy of Sciences

authors： Michaels M

更新日期：1998-12-30 00:00:00

abstract：:The past three decades of clinical disappointments in treating stroke must compel us to rethink our strategy. Given the enormous complexity of the clinical disease, the "one size fits all" approach to stroke treatment is unlikely to succeed. The effective treatment of stroke aimed at reversing ischemic injury will req...

journal_title：Annals of the New York Academy of Sciences

authors： Joshi S,Agarwal S

更新日期：2010-06-01 00:00:00

abstract：:Mitochondrial dysfunction is implicated in many forms of cell death, particularly in the central nervous system. The mitochondria are required at the same time to generate adenosine 5'-triphosphate (ATP) for the cell, sequester excess cytoplasmic Ca(2+), and both produce and detoxify superoxide free radicals. The elec...

journal_title：Annals of the New York Academy of Sciences

authors： Nicholls DG

更新日期：2008-12-01 00:00:00

abstract：:Though only a decade has elapsed since the default network (DN) was first defined as a large-scale brain system, recent years have brought great insight into the network's adaptive functions. A growing theme highlights the DN as playing a key role in internally directed or self-generated thought. Here, we synthesize r...

journal_title：Annals of the New York Academy of Sciences

authors： Andrews-Hanna JR,Smallwood J,Spreng RN

更新日期：2014-05-01 00:00:00

abstract：:Adult (3-month-old) and aged (28-month-old) rats that had been pretreated with 5,7-DHT in both lateral ventricles received grafts of cell suspensions taken from the RR or MR regions taken from the embryonic stages E12-21. These cell suspensions were implanted unilaterally into the rostral part of the hippocampus or th...

journal_title：Annals of the New York Academy of Sciences

authors： Steinbusch HW,Beek A,Frankhuyzen AL,Tonnaer JA,Gage FH,Björklund A

更新日期：1987-01-01 00:00:00