Sperm phagocytosis by corona cells in a human in vitro fertilization system.

abstract：:Recent controversies in the existence of saturable binding of general anesthetics in brain tissues prompted a careful examination of specific binding of anesthetics to neural receptors. We examined the binding of both local and general anesthetics using electron spin resonance and radioligand criteria. Our results sug...

journal_title：Annals of the New York Academy of Sciences

authors： Lin L,Koblin DD,Wang HH

更新日期：1991-01-01 00:00:00

abstract：:AH-66 rat ascites hepatoma cells incorporated [14C]leucine into the AFP fraction. In a cell-free system, hepatoma ribosomes were found to be active in AFP synthesis whereas the supernatant fraction from hepatoma had no specific effect on AFP production. The amount of [14C]leucine incorporated in AFP by membrane-bound ...

journal_title：Annals of the New York Academy of Sciences

authors： Kanai K,Endo Y,Oda T,Kaneko Y

更新日期：1975-08-22 00:00:00

abstract：:The human organism is in a state of dynamic equilibrium, homeostasis. The stress system is activated when homeostasis is challenged by extrinsic or intrinsic forces, the stressors. This system, whose central component is the central nervous system (CNS) and includes corticotropin-releasing hormone (CRH) and noradrener...

journal_title：Annals of the New York Academy of Sciences

authors： Stratakis CA,Chrousos GP

更新日期：1995-12-29 00:00:00

abstract：:Single-agent topotecan is an active drug in chemotherapy-naive MDS and CMML and, to a lesser degree, in refractory/relapsed acute leukemias, low-/intermediate-grade lymphoma, and myeloma. Its combination with cytosine arabinoside induces complete remissions in high-risk MDS/CMML. A triple-combination regimen of cyclop...

journal_title：Annals of the New York Academy of Sciences

authors： Beran M,Kantarjian HM

更新日期：2000-01-01 00:00:00

abstract：:The aim of our work was to detect minor loci acting as Alzheimer's disease (AD) genetic markers. We divided 206 AD patients and 186 individuals as controls into six age at onset/age-dependent groups. We studied polymorphisms of the genes of apolipoprotein E (APOE) and its promoter, cathepsin D, butyrylcholinesterase, ...

journal_title：Annals of the New York Academy of Sciences

authors： Beyer K,Lao JI,Latorre P,Ariza A

更新日期：2005-12-01 00:00:00

abstract：:A 1.2 kb polymorphic fragment from the Gardel isolate of Ehrlichia (formerly Cowdria) ruminantium was used to isolate a 15kb clone from the E. ruminantium Welgevonden LambdaGEM-11 library. This clone, WL2EL1, was subcloned and sequenced. Eight open reading frames (ORFs) were identified. The ORF in WL2EL1 which contain...

journal_title：Annals of the New York Academy of Sciences

authors： Louw E,Brayton KA,Collins NE,Pretorius A,Van Strijp F,Allsopp BA

更新日期：2002-10-01 00:00:00

abstract：:A recent study showed a significant association between schizophrenia in European samples and the glutamate cysteine ligase modifier (GCLM) subunit gene, which is the key glutathione (GSH)-synthesizing enzyme. Since the symptoms of methamphetamine (METH)-induced psychosis are similar to those of schizophrenia, the GCL...

journal_title：Annals of the New York Academy of Sciences

authors： Kishi T,Ikeda M,Kitajima T,Yamanouchi Y,Kinoshita Y,Kawashima K,Inada T,Harano M,Komiyama T,Hori T,Yamada M,Iyo M,Sora I,Sekine Y,Ozaki N,Ujike H,Iwata N

更新日期：2008-10-01 00:00:00

abstract：:The role of dopaminergic activity in susceptibility of methamphetamine (MAP) psychosis (flashbacks) to subsequent spontaneous recurrences was studied. Plasma monoamine metabolite levels were assayed in 23 flashbackers, of whom 10 experienced a single flashback, 8 exhibited subsequent flashbacks and 5 with the last epi...

journal_title：Annals of the New York Academy of Sciences

authors： Yui K,Goto K,Ikemoto S

更新日期：2004-10-01 00:00:00

abstract：:Locomotion control uses proprioceptive, visual, and vestibular signals. Previously, we analyzed the visual contribution with visual motion stimulation in roll while participants kept their heads in a normal upright orientation. In this study we applied the same visual disturbance in a head-upright and a nose-down cond...

journal_title：Annals of the New York Academy of Sciences

authors： Bardins S,Schneider E

更新日期：2009-05-01 00:00:00

abstract：:The lysosomal system has often been considered a prominent morphologic marker of distressed or dying neurons. Lysosomes or their constituent hydrolases have been viewed in different neuropathologic states as either initiators and direct agents of cell death, agents of cellular repair and recompensation, effectors of e...

journal_title：Annals of the New York Academy of Sciences

authors： Nixon RA,Cataldo AM

更新日期：1993-05-28 00:00:00

abstract：:Relaxin (RLX) has antifibrotic effects in a number of tissues. Many of these effects are similar to those induced by the activators of peroxisome proliferator-activated receptor gamma (PPARgamma), raising the possibility that a mechanism for RLX's antifibrotic effects may involve activation of the PPARgamma pathway. T...

journal_title：Annals of the New York Academy of Sciences

authors： Singh S,Bennett RG

更新日期：2009-04-01 00:00:00

abstract：:Bioelectrical impedance analysis (BIA) has been proposed for measuring fat-free mass, total body water, percent fat, body cell mass, intracellular water, and extracellular water: a veritable laboratory in a box. Although it is unlikely that BIA is quite this versatile, correlations have been demonstrated between BIA a...

journal_title：Annals of the New York Academy of Sciences

authors： Schoeller DA

更新日期：2000-05-01 00:00:00

abstract：:Propagation and prolongation of rapid neuronal discharge underlies the epilepsies. However, episodic focal rapid neuronal discharges limited to discrete nuclei and pathways of the amygdala-hippocampal-septal-hypothalamic networks are the language of physiologic message systems for endocrine regulation and reproductive...

journal_title：Annals of the New York Academy of Sciences

authors： Stevens JR

更新日期：1999-06-29 00:00:00

abstract：:T cell protein tyrosine phosphatase (TCPTP) dephosphorylates a number of substrates, including JAK-STAT (signal transducer and activator of transcription) signaling proteins, which are activated by interferon (IFN)-γ, a major proinflammatory cytokine involved in conditions such as inflammatory bowel disease. A critica...

journal_title：Annals of the New York Academy of Sciences

authors： Krishnan M,McCole DF

更新日期：2017-10-01 00:00:00

abstract：:Obesity and Type 2 diabetes are now major public health issues in developed nations and have reached epidemic proportions in many developing nations, as well as disadvantaged groups in developed countries, e.g., Mexican-Americans, African-Americans, and Australian Aborigines. These groups all show hyperinsulinemia and...

journal_title：Annals of the New York Academy of Sciences

authors： Zimmet P,Boyko EJ,Collier GR,de Courten M

更新日期：1999-11-18 00:00:00

abstract：:Post-polio syndrome (PPS) describes the clinical onset of progressive muscular weakness many years after survival of acute paralytic poliomyelitis, often in muscle groups clinically unaffected by the original disease process. Prior pathologic descriptions of this often disabling, but not usually fatal, syndrome have b...

journal_title：Annals of the New York Academy of Sciences

authors： Miller DC

更新日期：1995-05-25 00:00:00

abstract：:Despite a globally uniform increase in the concentrations of emitted greenhouse gases, radiatively forced surface warming can have significant spatial variations. These define warming patterns that depend on preexisting climate states and through atmospheric and oceanic dynamics can drive changes of the hydrological c...

journal_title：Annals of the New York Academy of Sciences

authors： Ma J,Zhou L,Foltz GR,Qu X,Ying J,Tokinaga H,Mechoso CR,Li J,Gu X

更新日期：2020-07-01 00:00:00

abstract：:The CD27(+) IgD(+) B cell population, known as IgM memory, reduces with age. It is thought that this population is responsible for pneumococcal polysaccharide T-independent responses, and that the age-related reduction might be partially responsible for the increased susceptibility of older people to bacterial pathoge...

journal_title：Annals of the New York Academy of Sciences

authors： Martin V,Wu YC,Kipling D,Dunn-Walters DK

更新日期：2015-12-01 00:00:00

abstract：:Rodent models have been used for many years to probe the actions of relaxin. Identification of the orthologs of human leucine-rich repeat-containing g-protein-coupled receptor 7 (LGR7), the relaxin receptor, in mouse and rat will enable characterization of the response of LGR7 to relaxin in these species. Partial LGR7...

journal_title：Annals of the New York Academy of Sciences

authors： Scott DJ,Layfield S,Riesewijk A,Morita H,Tregear GW,Bathgate RA

更新日期：2005-05-01 00:00:00

abstract：:The presented paper describes a multi-disciplinary cooling selection approach applied to major gas turbine engine hot section components, including turbine nozzles, blades, discs, combustors and support structures, which maintain blade tip clearances. The paper demonstrates benefits of close interaction between partic...

journal_title：Annals of the New York Academy of Sciences

authors： Glezer B

更新日期：2001-05-01 00:00:00

abstract：:Sponsored by the New York Academy of Sciences and with support from the National Institute of Mental Health, the Life Technologies Foundation, and the Josiah Macy Jr. Foundation, "Advancing Drug Discovery for Schizophrenia" was held March 9-11 at the New York Academy of Sciences in New York City. The meeting, comprisi...

journal_title：Annals of the New York Academy of Sciences

authors： Marder SR,Roth B,Sullivan PF,Scolnick EM,Nestler EJ,Geyer MA,Welnberger DR,Karayiorgou M,Guidotti A,Gingrich J,Akbarian S,Buchanan RW,Lieberman JA,Conn PJ,Haggarty SJ,Law AJ,Campbell B,Krystal JH,Moghaddam B,Sawa A

更新日期：2011-10-01 00:00:00

abstract：:A majority of incidentally found adrenal tumors derive from the adrenal cortex. The aim of our study was evaluation of the incidence of chromaffin tumors in a group of 1,111 patients with adrenal incidentalomas. In this group there were 803 women and 308 men, aged 10-87 years. Clinical examination, imaging studies (ul...

journal_title：Annals of the New York Academy of Sciences

authors： Kasperlik-Zaluska AA,Roslonowska E,Slowinska-Srzednicka J,Otto M,Cichocki A,Cwikla J,Slapa R,Eisenhofer G

更新日期：2006-08-01 00:00:00

abstract：:We have previously demonstrated that wild-type herpes simplex virus type 1 (HSV-1), as well as nonreplicating UV-inactivated HSV-1, promptly activates the nuclear factor-kappaB (NF-kappaB) in U937 monocytoid cells and that glycoprotein D (gD) of HSV-1 is sufficient by itself to exert a similar effect. We then investig...

journal_title：Annals of the New York Academy of Sciences

authors： Teresa Sciortino M,Medici MA,Marino-Merlo F,Zaccaria D,Giuffrè M,Venuti A,Grelli S,Mastino A

更新日期：2007-01-01 00:00:00

abstract：:Transcriptional profiling and functional genomics experiments using E11.5 metanephros organ cultures from Ahr(-/-) and Ahr(+/+) have shown that aryl hydrocarbon receptor (AHR) transcription factor is involved in the regulation of mesenchymal-to-epithelial transition (MET) during nephrogenesis. This response is mediate...

journal_title：Annals of the New York Academy of Sciences

authors： Ramos KS

更新日期：2006-09-01 00:00:00

abstract：:The current trend in antipoverty policy emphasizes mandated empowerment: the poor are being handed the responsibility for making things better for themselves, largely without being asked whether this is what they want. Beneficiary control is now being built into public service delivery, while microcredit and small bus...

journal_title：Annals of the New York Academy of Sciences

authors： Banerjee AV,Duflo E

更新日期：2008-01-01 00:00:00

abstract：:Natural systems cannot be closed to the environment. At the same time there is a necessity for closure in order to build the system. It is this quint-essential tension between openness and closure that drives systems to unfold into further stages or levels of growth and development. In other words, the emergence of or...

journal_title：Annals of the New York Academy of Sciences

authors： Alvarez De Lorenzana JM

更新日期：2000-01-01 00:00:00

abstract：:The existence of a covalent intermediate in topoisomerase I catalysis allows uncoupling of the cleavage and ligation half-reactions on partially single-stranded DNA substrates containing a highly preferred interaction site. Using this model DNA substrate system we have demonstrated that the cleavage reaction requires ...

journal_title：Annals of the New York Academy of Sciences

authors： Christiansen K,Westergaard O

更新日期：1996-12-13 00:00:00

abstract：:The therapeutic value of thymectomy for myasthenia is still questioned although it retains an important place among management modalities that strive for sustained remission. Questions derive from uncertainty as to appropriate timing, variable extent of resection and quantitation of response. Forty-seven patients, fol...

journal_title：Annals of the New York Academy of Sciences

authors： Penn AS,Jaretzki A 3rd,Wolff M,Chang HW,Tennyson V

更新日期：1981-01-01 00:00:00

abstract：:The influence of either short-term fasting or vitamin E administration on insulin action was studied in two groups of obese Type 2 diabetic patients. Twelve patients underwent 7 days of fasting (group A), whereas 600 mg of vitamin E was administered daily during 3 months in 9 diabetic patients (group B). Insulin actio...

journal_title：Annals of the New York Academy of Sciences

authors： Skrha J,Sindelka G,Hilgertová J

更新日期：1997-09-20 00:00:00

abstract：:Gene therapy for beta-globinopathies, particularly beta-thalassemia and sickle cell anemia, hold much promise for the future, as a one time cure for these common and debilitating disorders. Correction of the beta-globinopathies using lentivirus vectors (LV) carrying the beta- or gamma-globin genes and elements of the ...

journal_title：Annals of the New York Academy of Sciences

authors： Perumbeti A,Malik P

更新日期：2010-08-01 00:00:00