An analysis of vincristine-resistance in BHK cells pretreated with 1-beta-D-arabinofuranosylcytosine.

abstract：:In 1992 The International Registry of Inferior Vena Cava (IVC) Leiomyosarcomas was established to study the pathogenesis and natural history of the tumor and to support the most rational treatment. We collected 218 patients through a literature review and personal communications. We corresponded with several Authors t...

journal_title：Anticancer research

authors： Mingoli A,Cavallaro A,Sapienza P,Di Marzo L,Feldhaus RJ,Cavallari N

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND/AIM:There is no clear evidence in the literature regarding the regulation of programmed cell death-ligand 1 (PD-L1) expression by cyclo-oxygenase-2 (COX2). In this study, whether PD-L1 expression was regulated by COX2 activity was examined in vitro. MATERIALS AND METHODS:Resected lung cancer specimens were ...

journal_title：Anticancer research

authors： Shimizu K,Okita R,Saisho S,Maeda AI,Nojima Y,Nakata M

更新日期：2018-08-01 00:00:00

abstract：AIM:The American thyroid association (ATA) recommends that additional imaging procedures supplement cervical ultrasonography (US) in any patient with a basal calcitonin value above 150 pg/ml in the follow-up of medullary thyroid carcinoma (MTC). The aim of the present study was to reaffirm or challenge this cut-off for...

journal_title：Anticancer research

authors： Sesti A,Mayerhoefer M,Weber M,Anner P,Wadsak W,Dudczak R,Haug A,Karanikas G

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND/AIM:Ouabain, a plant-derived product/substance with Na+/K+-ATPase inhibiting properties, has been shown to exert anti-cancer activity on human cancer cells. This is the first study to investigate the effect of ouabain on apoptotic cell death of human osteosarcoma-derived U-2 OS cells. MATERIALS AND METHODS:...

journal_title：Anticancer research

authors： Chou WH,Liu KL,Shih YL,Chuang YY,Chou J,Lu HF,Jair HW,Lee MZ,Au MK,Chung JG

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIM:Metastases involving the adrenal glands can be treated surgically or with radiation therapy. Retrospective studies indicate that radiotherapy for this indication is safe, well-tolerated and associated with symptom palliation and good local control. We conducted this analysis to report on patterns and out...

journal_title：Anticancer research

authors： Buergy D,Rabe L,Siebenlist K,Stieler F,Fleckenstein J,Giordano FA,Wenz F,Boda-Heggemann J

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Studies have recommended a 21-gene recurrence score (RS) to optimize adjuvant treatment for patients with early-stage breast cancer (EBC) with hormone receptor-positive (HR+) and human epidermal growth factor receptor-2 negative (HER2-) tumors. This study aimed to prospectively evaluate the impact of this RS...

journal_title：Anticancer research

authors： Zeng Y,Li Q,Qin T,Li S,Jin L,Wu J,Chen K,Deng H,Rao N,Liu Q,Su F,Jia W,Yao H

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Various localized side effects which accompany head and neck irradiation [IR] have been widely reported. However, systemic side effects/have been only sparsely reported in the short-term period post-IR in an animal model. The potential modulatory role of zinc-desferrioxamine [Zn-DFO] on IR effects was examin...

journal_title：Anticancer research

authors： Nagler RM,Barak V,Nagler A

更新日期：2000-05-01 00:00:00

abstract：:A better understanding of the non-targeted (bystander) effects of radiation may have important implications with regards to radiation risk assessment, radiation protection, and targeted cancer therapy. In the present study, the direct and bystander effects of α-particle irradiation in immortalized human fibroblasts (F...

journal_title：Anticancer research

authors： Dahle J,Kalanxhi E,Tisnek N

更新日期：2011-06-01 00:00:00

abstract：:The development of T-lymphocytes (T cells) constitute one of the basic and most vital processes in immunology. Conventional mathematical models, being based on the systems theory, fail to sufficiently distinguish the constituents of thymocytes and are thus of limited significance. On the basis of some well thought-out...

journal_title：Anticancer research

authors： Wang G,Krueger GR,Buja LM

更新日期：2004-05-01 00:00:00

abstract：:Three histamine H2-receptor antagonists, Cimetidine, Metiamide and Ranitidine, were tested for their inhibitory effect on two experimental bowel cancer models. In the first model mitotic rates were measured in dimethylhydrazine-induced tumors of rat colon and in the second model volumetric changes in human large bowel...

journal_title：Anticancer research

authors： Tutton PJ,Barkla DH

更新日期：1983-01-01 00:00:00

abstract：:Linomide has antitumor effects when administered in vivo but not in vitro. Recent data indicate that at least part of this effect can be attributed to anti-angiogenic properties. The aim of the present investigation was to study the anti-angiogenic effects of Linomide on early tumor-induced angiogenesis in vivo, using...

journal_title：Anticancer research

authors： Borgström P,Torres Filho IP,Hartley-Asp B

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND/AIM:Vanek's tumor is an inflammatory fibroid polyp (IFP) of very low incidence, which originates in the submucosa of the stomach, duodenum, jejunum and ileum. The etiology of this tumor is still unknown. Histologically, IFP is characterized by submucosal spindle cell proliferation in fibromyxoid stroma with ...

journal_title：Anticancer research

authors： Jukic Z,Ferencic Z,Radulovic P,Mijic A,Fucic A

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:In an attempt to find a more sensitive and specific non-invasive diagnostic assay for the detection of bladder cancer cells, the authors assayed the exfoliated cells from patient's voided urine and bladder washing fluids for the presence of telomerase, an enzyme that maintains a cell's chromosomal length, me...

journal_title：Anticancer research

authors： Eissa S,Swellam M,el-Mosallamy H,Mourad MS,Hamdy N,Kamel K,Zaglol AS,Khafagy MM,el-Ahmady O

更新日期：2003-09-01 00:00:00

abstract：:Considerable progress has recently been achieved in understanding the pathogenesis of human immunodeficiency virus type 1 (HIV-1), and in improving the efficacy of antiretroviral therapies for the treatment of patients with the acquired immunodeficiency syndrome (AIDS). The pharmacological properties of new drugs are ...

journal_title：Anticancer research

authors： Romano G,Massi D,Giordano A

更新日期：1998-07-01 00:00:00

abstract：:UGP (Urinary gonadotropin peptide) also know as urinary gonadotropin fragment (UGF) or the beta-core of hCG (c beta hCG), was identified as a peptide with a molecular weight of 10.5 kD, having the same amino acid sequence as the core section of the beta-subunit of human chorionic gonadotropin. UGP has been found in no...

journal_title：Anticancer research

authors： el-Ahmady O,Halim AB,Gad M,Walker R

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND/AIM:Exposure of the skin to sunshine is the major natural source of vitamin D. In order to imitate this natural production of vitamin D for patients with chronic kidney disease, hemodialysis patients were exposed three times a week to radiation of the front part of both legs to normalize the vitamin D status...

journal_title：Anticancer research

authors： Krause R,Stange R,Roth HJ,Kaase H,Michalsen A,Holick MF

更新日期：2018-02-01 00:00:00

abstract：:A sarcomatoid carcinoma cell line (SAR-HCV) was established from a malignant liver lesion of a patient infected with hepatitis C virus. SAR-HCV cells were successfully xenografted in SCID mice. Vimentin was strongly positive in cultured SAR-HCV cells, the primary tumour lesion and the xenografts. Hepatocyte paraffin 1...

journal_title：Anticancer research

authors： Tai DI,Shen YJ,Weng WH,Chen HW,Kang CC,Chen TC,Liao SK

更新日期：2011-01-01 00:00:00

abstract：:Chk1 (checkpoint kinase 1) is a serine-threonine kinase that is critical for G2/M arrest in response to DNA damage. Chk1 phosphorylates Cdc25C at serine-216, a major regulatory site, in response to DNA damage. Furthermore, Chk1 also phosphorylates Cdc25A on serine 123 which accelerates its degradation through the ubiq...

journal_title：Anticancer research

authors： Han EK,Butler C,Zhang H,Severin JM,Qin W,Holzman TF,Gubbins EJ,Simmer RL,Rosenberg S,Giranda VL,Ng SC,Luo Y

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Recently, 14-member macrolide antibiotics such as Clarithromycin and Roxithromycin (RXM) have been shown to have anti-cancer and anti-angiogeneic effects. However, it is not fully understood whether and how RXM suppresses angiogenesis in human hepatoma, which is a well-known hypervascular tumor. MATERIALS A...

journal_title：Anticancer research

authors： Aoki D,Ueno S,Kubo F,Oyama T,Sakuta T,Matsushita K,Maruyama I,Aikou T

更新日期：2005-01-01 00:00:00

abstract：:The usefulness of prostate specific antigen (PSA) in screening for prostatic carcinoma was studied in 262 inpatients of the department of internal medicine. All patients underwent a rectal digital examination and determination of PSA by the Tandem-E method (Hybritech). The plan was to perform biopsies if there were su...

journal_title：Anticancer research

authors： Waidelich R,Jansen HM,Stieber P,Schmeller N,Lamerz R,Werdan K,Fateh-Moghadam A

更新日期：1997-07-01 00:00:00

abstract：:The relationship between apoptosis and chemosensitivity remains complex. We tested the chemosensitivity of 45 patients with advanced breast cancer (BC) ex vivo against anthracyclines (A: doxorubicin, epirubicin), taxanes (T: paclitaxel, docetaxel), cisplatin (DDP) and CMF and any correlation with the expression of p53...

journal_title：Anticancer research

authors： Rein DT,Schöndorf T,Breidenbach M,Janát MM,Weikelt A,Göhring UJ,Becker M,Mallmann P,Kurbacher CM

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:The optimal treatment for locoregionally recurrent rectal cancer after curative surgery has not yet been defined. The definition of prognostic factors could lead to the selection of an aggressive therapeutic approach in patients with favourable prognosis alone. PATIENTS AND METHODS:The records of thirty-nin...

journal_title：Anticancer research

authors： Pergolizzi S,Settineri N,Santacaterina A,Maisano R,Frosina P,Loria F,Nardella G,Garufi G,Sansotta G,De Renzis C

更新日期：1999-03-01 00:00:00

abstract：AIM:The purpose of this study was to assess the impairment of the submandibular gland, in terms of changes in volume by computed tomography (CT) and CT value, which was the mean pixel value at a region of interest, in a group of patients with head and neck cancer treated with radiation therapy (RT). PATIENTS AND METHO...

journal_title：Anticancer research

authors： Uchiyama Y,Kreiborg S,Murakami S,Tsujimoto T,Sumida I

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Breast cancer (BC) is the most common cancer in women, and the hormone receptor status is one of the most important prognostic factors in patients with BC. The aim of this study was to establish whether a relationship exists between the hormone receptor rate and the main classic risk factors in patients with...

journal_title：Anticancer research

authors： Lumachi F,Ermani M,Marino F,Di Cristofaro L,Tombolan V,Brunello A,Roma A,Basso U

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIMS:Our study aimed to compared 3-year results following laparoscopy-assisted proximal gastrectomy (LAPG)-double tract anastomosis (DTA) and lower esophageal sphincter-preserving LAPG (LES-LAPG). PATIENTS AND METHODS:Nine patients who underwent LES-LAPG and 23 LAPG-DTA were compared regarding 3-year follow...

journal_title：Anticancer research

authors： Kim DJ,Kim W

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIM:Methionine inhibits proliferation of breast and prostate cancer cells. This study aimed to determine cell cycle effects of methionine and selectivity for cancer cells. MATERIALS AND METHODS:MCF-7 (breast), LNCaP (prostate), and LS-174 (colon) cancer cells (wild-type p53), DU-145 (prostate) and SW480 (co...

journal_title：Anticancer research

authors： Benavides MA,Hagen KL,Fang W,Du P,Lin S,Moyer MP,Yang W,Bland KI,Grizzle WE,Bosland MC

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:The present project studied the implications of using the irregular surface compensator (ISC) technique in comparison to three-dimensional conformal radiation therapy (3D-CRT) for breast cancer treatment. ISC is an electronic compensation algorithm that modulates the fluence across the radiation fields to compe...

journal_title：Anticancer research

authors： Flejmer AM,Josefsson D,Nilsson M,Stenmarker M,Dasu A

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND/AIM:Seizures represent a major problem for patients with brain metastases. This study evaluated the role of seizures in patients receiving single-fraction radiosurgery (SRS) or multi-fraction stereotactic radiotherapy (FSRT). PATIENTS AND METHODS:This retrospective study included 195 patients receiving SRS ...

journal_title：Anticancer research

authors： Rades D,Witteler J,Kjaer TW,Tvilsted S,Schild SE

更新日期：2020-06-01 00:00:00

abstract：AIM:This retrospective observational study evaluated the role of hypo-fractionated stereotactic radiotherapy (SRT) in patients with oligo-progressive metastatic renal cell carcinoma (mRCC) treated with first-line oral tyrosine kinase inhibitors (TKI). Data on local control, delay of further progression, and safety are ...

journal_title：Anticancer research

authors： Gebbia V,Girlando A,DI Grazia A,Fazio I,Borsellino N,Piazza D,Serretta V,Pergolizzi S,Pontoriero A,Firenze A,Valerio MR

更新日期：2020-12-01 00:00:00

abstract：:We investigated whether the levels of the DNA-dependent protein kinase (DNA-PK) activity and content correlate with drug sensitivity in different tumour materials and if this can be utilised in predicting treatment outcome. DNA-PK activity and expression were investigated in tumour cells from 8 patients with chronic l...

journal_title：Anticancer research

authors： Eriksson A,Lewensoh R,Larsson R,Nilsson A

更新日期：2002-05-01 00:00:00