Lower Esophageal Sphincter-preserving Anastomosis Is an Acceptable Reconstruction Method Following Laparoscopy-assisted Proximal Gastrectomy.

Abstract:

BACKGROUND/AIMS:Our study aimed to compared 3-year results following laparoscopy-assisted proximal gastrectomy (LAPG)-double tract anastomosis (DTA) and lower esophageal sphincter-preserving LAPG (LES-LAPG). PATIENTS AND METHODS:Nine patients who underwent LES-LAPG and 23 LAPG-DTA were compared regarding 3-year follow-up complications, the anemia-related parameter and albumin levels. RESULTS:During the 3-year follow-up period, no patient (0%) in the LES-LAPG and six patients (6/23, 26.1%) in the LAPG-DTA group developed reflux symptoms. Reflux symptoms were well controlled with PPI in all patients, except for one in the LAPG-DTA group. In the laboratory study, there were no differences in serum ferritin and vitamin B12 levels between the two groups. However, mean hemoglobin and albumin levels were significantly higher in the LES-LAPG group from 18 months postoperatively. CONCLUSION:LES-LAPG provided acceptable results for the prevention of reflux esophagitis. Moreover, LES-LAPG may be advantageous for anemia prevention and nutritional status improvement compared to LAPG-DTA.

journal_name

Anticancer Res

journal_title

Anticancer research

authors

Kim DJ,Kim W

doi

10.21873/anticanres.13129

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

425-430

issue

1

eissn

0250-7005

issn

1791-7530

pii

39/1/425

journal_volume

39

pub_type

杂志文章
  • Aloe vera Extract Suppresses Proliferation of Neuroblastoma Cells In Vitro.

    abstract:BACKGROUND/AIM:Neuroblastoma is a pediatric solid tumor refractory to eradication by chemotherapy. To determine whether Aloe vera (AV), a pontial anticancer reagent, could be useful in neuroblastoma therapy, we investigated the anti-proliferative effects of an AV protein extract. MATERIALS AND METHODS:Human neuroblast...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Yonehara A,Tanaka Y,Kulkeaw K,Era T,Nakanishi Y,Sugiyama D

    更新日期:2015-08-01 00:00:00

  • Lysozyme is up-regulated in columnar-lined Barrett's mucosa: a possible natural defence mechanism against Barrett's esophagus-associated pathogenic bacteria.

    abstract:BACKGROUND:Lysozyme is a natural antimicrobial enzyme that is up-regulated in inflammatory diseases of the gastrointestinal tract. Pathogenic microbes have recently been identified in the esophageal mucosa in patients with Barrett's esophagus (BE). Lysozyme expression was evaluated in biopsies from patients with BE. M...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Rubio CA

    更新日期:2012-11-01 00:00:00

  • Safety and Efficacy of Carbon-ion Radiotherapy Alone for Stage III Non-small Cell Lung Cancer.

    abstract:BACKGROUND/AIM:We evaluated the efficacy and safety of carbon-ion radiotherapy (CIRT) alone for Stage III non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS:Data of 65 patients (median age=73 years) with Stage III NSCLC who underwent CIRT alone in the QST Hospital, Chiba, Japan, between 1997 and 2015 were retros...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:10.21873/anticanres.13963

    authors: Anzai M,Yamamoto N,Hayashi K,Nakajima M,Nomoto A,Ogawa K,Tsuji H

    更新日期:2020-01-01 00:00:00

  • Process development for the practical production of eldecalcitol by linear, convergent and biomimetic syntheses.

    abstract::Eldecalcitol [1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D(3)], an analog of calcitriol (1α,25-dihydroxyvitamin D(3)), possesses a hydroxypropoxy substituent at the 2β-position of calcitriol. Eldecalcitol has potent biological effects on bone disease such as osteoporosis. The marketing of eldecalcitol has very recen...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Kubodera N,Hatakeyama S

    更新日期:2012-01-01 00:00:00

  • Metastasis Suppressor NME1 Directly Activates Transcription of the ALDOC Gene in Melanoma Cells.

    abstract:BACKGROUND/AIM:NME/NM23 nucleoside diphosphate kinase 1 (NME1) is a metastasis suppressor gene, exhibiting reduced expression in metastatic cancers and the ability to suppress metastatic activity of cancer cells. We previously identified NME1-regulated genes with prognostic value in human melanoma. This study was condu...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:10.21873/anticanres.12956

    authors: Pamidimukkala NV,Leonard MK,Snyder D,McCorkle JR,Kaetzel DM

    更新日期:2018-11-01 00:00:00

  • Left Ventricular Ejection Fraction Screening and Clinical Decision-making in Metastatic HER2-positive Breast Cancer.

    abstract:BACKGROUND:Antibodies against human epidermal growth factor receptor 2 (HER2) affect metastatic breast cancer cells and cardiac myocytes. Guidelines recommend evaluation of cardiac ejection fraction (EF) every 3 months despite little supporting evidence for this need. We assessed the impact of EF screening on clinical ...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:10.21873/anticanres.11749

    authors: Mescher C,Ding C,Defor T,Konety S,Blaes A

    更新日期:2017-07-01 00:00:00

  • CEA as a prognostic factor in colorectal cancer.

    abstract::We have measured serum CEA levels in 207 patients with colorectal cancer. CEA sensitivity was related to tumor stage in tumors located in the right colon, but not in tumors located in the left colon or the rectum. CEA had prognostic value in patients with tumors located in the right colon (p < 0.001) but not in the le...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Filella X,Molina R,Piqué JM,Grau JJ,Garcia-Valdecasas JC,Biete A,Novell F,Astudillo E,Bordas JM,Campo E

    更新日期:1994-03-01 00:00:00

  • PCNA--a cell proliferation marker in vocal chord cancer. Part I: Premalignant laryngeal lesions.

    abstract::Laryngeal hyperkeratotic lesions can progress to fully developed malignant carcinoma in some cases. These premalignant lesions are proliferative disorders whose potential for further tumour progression is perhaps difficult to assess by mere histology. Immunostaining with PCNA, a protein correlated with cell proliferat...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Pignataro LD,Broich G,Lavezzi AM,Biondo B,Ottaviani F

    更新日期:1995-07-01 00:00:00

  • Expression of cathepsin-D in primary breast cancer and corresponding local recurrence or metastasis: an immunohistochemical study.

    abstract:BACKGROUND/AIM:The role of cathepsin-D is well established in breast cancer progression, being correlated with worse clinical outcomes. However, to our knowledge, no study has been performed investigating its expression in primary breast cancer tumors and their corresponding recurrences or metastasis. MATERIALS AND ME...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Dian D,Vrekoussis T,Shabani N,Mylonas I,Kuhn C,Schindlbeck C,Navrozoglou I,Friese K,Makrigiannakis A,Jeschke U

    更新日期:2012-03-01 00:00:00

  • Cytotoxic Effect of Nano-SiO2 in Human Breast Cancer Cells via Modulation of EGFR Signaling Cascades.

    abstract:BACKGROUND/AIM:Silica nanoparticles (nano-SiO2) are widely used in many industrial areas and there is much controversy surrounding cytotoxic effects of such nanoparticles. In order to determine the toxicity and possible molecular mechanisms involved, we conducted several tests with two breast cancer cell lines, MDA-MB-...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:10.21873/anticanres.12068

    authors: Jeon D,Kim H,Nam K,Oh S,Son SH,Shin I

    更新日期:2017-11-01 00:00:00

  • A Prognostic Nomogram for Overall Survival of Patients After Hepatectomy for Intrahepatic Cholangiocarcinoma.

    abstract:AIM:We hypothesized that a nomogram can accurately predict overall survival (OS) for patients with intrahepatic cholangiocarcinoma (ICC) after hepatectomy. MATERIALS AND METHODS:A nomogram to predict OS based was developed using data from 185 ICC patients who had undergone hepatectomy. The nomogram was evaluated by co...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Yeh CN,Wang SY,Chen YY,Chen MH,Chiang KC,Cheng CT,Tsai CY,Wang CC,Yeh TS,Chen TC

    更新日期:2016-08-01 00:00:00

  • The Impact of TIMM17A on Aggressiveness of Human Breast Cancer Cells.

    abstract:BACKGROUND:The mitochondrial protein translocase of inner mitochondrial membrane 17 homolog A (TIMM17A) has been identified as a biomarker of breast cancer. The present study aimed to investigate the biological role of TIMM17A in human breast cancer cells. MATERIALS AND METHODS:Anti-TIMM17A transgenes were stably tran...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Yang X,Si Y,Tao T,Martin TA,Cheng S,Yu H,Li J,He J,Jiang WG

    更新日期:2016-03-01 00:00:00

  • HPV33 DNA in premalignant and malignant breast lesions in Chinese and Japanese populations.

    abstract::The relationship between human papillomavirus (HPV) infection and breast cancer is controversial. In this study, paraffin-embedded tissue blocks prepared from 72 patients with benign, premalignant or malignant mammary lesions were randomly collected from the Shanghai region of China and Tokushima in Japan. DNA specime...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Yu Y,Morimoto T,Sasa M,Okazaki K,Harada Y,Fujiwara T,Irie Y,Takahashi E,Tanigami A,Izumi K

    更新日期:1999-11-01 00:00:00

  • Pre-treatment C-reactive protein as a prognostic factor for recurrence after surgical resection of hepatocellular carcinoma.

    abstract:BACKGROUND AND AIMS:We examined the prognostic value of pre-treatment C-reactive protein (CRP) after surgical resection (SR) for hepatocellular carcinoma (HCC). PATIENTS AND METHODS:A total of 298 patients with HCC who underwent SR were analyzed. They were categorized into a CRP-positive group (group A: CRP >0.2 mg/dl...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Nishikawa H,Arimoto A,Wakasa T,Kita R,Kimura T,Osaki Y

    更新日期:2013-03-01 00:00:00

  • Prognostic Factors and Treatment of Early-stage Small-cell Lung Cancer.

    abstract:BACKGROUND/AIM:Only 0.1-0.17% of all lung cancer patients are diagnosed with stage I or II small cell lung cancer (SCLC). Radiochemotherapy remains the standard treatment for limited stage disease. This study focused on prognostic factors in early stage SCLC treated with radiochemotherapy. PATIENTS AND METHODS:Seven f...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:10.21873/anticanres.11482

    authors: Käsmann L,Bolm L,Janssen S,Rades D

    更新日期:2017-03-01 00:00:00

  • Cell cycle arrest and apoptosis induced by oxaliplatin (L-OHP) on four human cancer cell lines.

    abstract:BACKGROUND:The effects of oxaliplatin (L-OHP) on cell cycle and apoptosis were examined. MATERIALS AND METHODS:The HT29, MCF7, Hela and A549 cell lines were treated and dual parameter flow cytometry BrdU/PI was then performed to monitor cell cycle modifications. Annexin V-FITC and PI probes were used for the detection...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: William-Faltaos S,Rouillard D,Lechat P,Bastian G

    更新日期:2006-05-01 00:00:00

  • A Novel 1,2-Dihydroquinoline Anticancer Agent and Its Delivery to Tumor Cells Using Cationic Liposomes.

    abstract:AIM:We screened nine 1,2-dihydro-quinolines using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) cytotoxicity assay in HepG2 and SMMC cells and identified ethyl-2-cyano-2-(2- (methoxycarbonyl)allyl)quinoline-1(2H)-carboxylate (compound 5) as a potential anticancer agent. In order to further deve...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Ma X,Wu YI,Yang X,Yang S,Li Y,Huang Y,Lee RJ,Bai T,Luo Y

    更新日期:2016-05-01 00:00:00

  • Reverse transcriptase-PCR analysis of apoptosis-regulating gene expression in human benign prostatic hyperplasia.

    abstract:BACKGROUND:To determine whether an imbalanced interaction between proapototic and antiapoptotic signals may account for the loss of the normal cell growth control in benign prostatic hyperplasia (BPH), the expression of some apoptosis-regulating genes (bcl-2, bax, c-myc, fas) was investigated. PATIENTS AND METHODS:BPH...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Angelucci C,Iacopino F,Lama G,Zelano G,Gianesini G,Sica G,Bono AV

    更新日期:2005-11-01 00:00:00

  • Oestrogen and progesterone receptor expression in patients with adenocarcinoma of the uterine cervix and correlation with various clinicopathological parameters.

    abstract:OBJECTIVE:The expression of oestrogen and progesterone receptors in patients with adenocarcinoma of the uterine cervix was examined in order to determine their influence on prognosis and to evaluate the association between the steroid receptor expression and various clinicopathologic parameters. PATIENTS AND METHODS:O...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Bodner K,Laubichler P,Kimberger O,Czerwenka K,Zeillinger R,Bodner-Adler B

    更新日期:2010-04-01 00:00:00

  • Acyl-Coenzyme A: Cholesterol Acyltransferase Inhibition in Cancer Treatment.

    abstract::Overexpression of acyl-coenzyme A:cholesterol acyltransferase (ACAT) results in increased cholesteryl ester levels and has been involved in a variety of cancer types. As a consequence, cholesterol metabolism has raised interest as a potential target for cancer treatment. Inhibition of ACAT results in suppression of pr...

    journal_title:Anticancer research

    pub_type: 杂志文章,评审

    doi:10.21873/anticanres.13482

    authors: Zabielska J,Sledzinski T,Stelmanska E

    更新日期:2019-07-01 00:00:00

  • Prognostic significance of T helper 1 and 2 and T cytotoxic 1 and 2 cells in patients with non-small cell lung cancer.

    abstract:BACKGROUND:We report the prognostic significance of peripheral and tumor-infiltrating Th1, Th2, Tc1 and Tc2 cells in lung cancer patients. MATERIALS AND METHODS:We evaluated the rates of interferon (IFN)-gamma+/CD4+ cells (Th1), interleukin (IL)-4+ /CD4+ cells (Th2), IFN-gamma+/CD8+ cells (Tc1), IL-4+ /CD8+ cells (Tc2...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Ito N,Suzuki Y,Taniguchi Y,Ishiguro K,Nakamura H,Ohgi S

    更新日期:2005-05-01 00:00:00

  • PB-100: a potent and selective inhibitor of human BCNU resistant glioblastoma cell multiplication.

    abstract::Major drawbacks to present-day cancer chemotherapy are its intrinsic lack of selectivity for tumour cells, resulting in severe damage to normal rapidly dividing cells, and the widespread emergence of drug resistance. Here experimental evidence is presented demonstrating that PB-100, a beta-carboline alkaloid, selectiv...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Beljanski M,Crochet S,Beljanski MS

    更新日期:1993-11-01 00:00:00

  • Renal cell carcinoma: relevance of angiogenetic factors.

    abstract::Angiogenesis is essential for tumour growth. Mostly hypervasculariced renal cell carcinoma (RCC) usually express angiogenic factors, e.g. basic fibroblast factor (bFGF), vascular endothelial growth factor, and angiogenin (ag). This study was designed to evaluate the improvement of serological angiogenesis-factors, the...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Wechsel HW,Bichler KH,Feil G,Loeser W,Lahme S,Petri E

    更新日期:1999-03-01 00:00:00

  • Effect of 5-fluorouracil on carcinoembryonic antigen expression and shedding at clonal level in colon cancer cells.

    abstract:BACKGROUND:The carcinoembryonic antigen (CEA) is a tumor marker largely utilized for the detection of minimal disease or as a target of immunotherapeutic approaches. In preclinical models CEA has been found to be up-regulated after exposure of cancer cells to 5-fluorouracil (5-FU). In the present study, the clonal dist...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Aquino A,Prete SP,Guadagni F,Greiner JW,Giuliani A,Orlando L,Masci G,De Santis S,Bonmassar E,Graziani G

    更新日期:2000-09-01 00:00:00

  • The Prognostic Value of the Perioperative Systemic Inflammation Score for Patients With Advanced Gastric Cancer.

    abstract:AIM:We examined whether the perioperative systemic inflammation score (SIS), which describes systemic inflammation and/or malnutrition, affected the tumor recurrence and survival in advanced gastric cancer patients. PATIENTS AND METHODS:The study retrospectively analyzed 160 patients with stage II/III gastric cancer w...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:10.21873/anticanres.14095

    authors: Hara K,Aoyama T,Yamada T,Nakazono M,Nagasawa S,Shimoda Y,Kumazu Y,Numata M,Hayashi T,Tamagawa H,Shiozawa M,Morinaga S,Yukawa N,Rino Y,Masuda M,Ogata T,Oshima T

    更新日期:2020-03-01 00:00:00

  • Multicenter evaluation of the Elecsys CA 125 II assay.

    abstract::The technical performance and clinical usefulness of the newly developed Elecsys CA 125 II assay (Boehringer Mannheim) was evaluated in a multicenter study. Imprecision studies were carried out using control sera and human pool sera with CA 125 concentrations from 11 to 1026 U/ml. Within-run CVs between 0.7 to 4.8% (m...

    journal_title:Anticancer research

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Hubl W,Chan DW,Van Ingen HE,Miyachi H,Molina R,Filella X,Pitzel L,Ruibal A,Rymer JC,Bagnard G,Domke I

    更新日期:1999-07-01 00:00:00

  • Prothymosin alpha augments deficient antitumor activity of monocytes from melanoma patients in vitro.

    abstract::Human peripheral blood monocytes derived from normal donors, melanoma patients (MP) before and after chemotherapy (MPa) were assayed for their capacity to inhibit SK-MEL-28 melanoma cell growth in vitro; in addition, growth modulating effects by prothymosin alpha 1 (ProTa) were studied. After preincubation with or wit...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Garbin F,Eckert K,Büttner P,Garbe C,Maurer HR

    更新日期:1994-11-01 00:00:00

  • Role of p21WAF1 in green tea polyphenol-induced growth arrest and apoptosis of oral carcinoma cells.

    abstract::The cyclin-dependent kinase inhibitor p21WAF1 participates in cell growth, differentiation, and apoptosis. p21WAF1 can be induced by green tea polyphenol EGCG in several cancer cell types, but its role in the oral cancer cell response to EGCG is not known. We found that EGCG upregulates p21WAF1 in an oral carcinoma ce...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Hsu S,Farrey K,Wataha J,Lewis J,Borke J,Singh B,Qin H,Lapp C,Lapp D,Nguyen T,Schuster G

    更新日期:2005-01-01 00:00:00

  • Combined gamma-tocotrienol and erlotinib/gefitinib treatment suppresses Stat and Akt signaling in murine mammary tumor cells.

    abstract:BACKGROUND:Heterodimer cooperation between ErbB receptors has limited clinical usefulness of receptor tyrosine kinase inhibitors (TKIs), erlotinib and gefitinib in the treatment of cancer. However, combination treatment of TKIs with gamma-tocotrienol targets multiple ErbB receptors and significantly inhibit +SA murine ...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Bachawal SV,Wali VB,Sylvester PW

    更新日期:2010-02-01 00:00:00

  • Intracellular metabolism, subcellular localization and phototoxicity of HMME/HB in ovarian cancer cells.

    abstract:BACKGROUND:Photodynamic therapy (PDT) is considered a promising new strategy for ovarian cancer treatment. As the key component in PDT, photosensitizer metabolism and localization in cancer cells is particularly important. MATERIALS AND METHODS:The localization of the photosensitizers hematoporphyrin monomethyl ether ...

    journal_title:Anticancer research

    pub_type: 杂志文章

    doi:

    authors: Song K,Li J,Li L,Zhang P,Geng F,Dong R,Yang Q,Qu X,Kong B

    更新日期:2011-10-01 00:00:00