Abstract:
:Rhizomelic chondrodysplasia punctata is a member of genetic peroxisomal disorders. Delayed myelination, which is probably related to the inadequacy of plasmalogens biosynthesis, is an important feature of this disorder. Direct assessment of neuropathologic aspects of RCDP syndrome such as neuronal degeneration and delayed myelination is possible with MR spectroscopy. In this report, MR spectroscopy findings (decreased Cho/Cr and increased Ins-Gly/Cr ratios and increased levels of mobile lipids) of a rhizomelic chondrodysplasia punctata case supporting delayed myelination are presented. This is the second report of MR spectroscopy examination of the specific brain metabolic changes associated with rhizomelic chondrodysplasia punctata.
journal_name
Magn Reson Imagingjournal_title
Magnetic resonance imagingauthors
Alkan A,Kutlu R,Yakinci C,Sigirci A,Aslan M,Sarac Kdoi
10.1016/s0730-725x(02)00625-2subject
Has Abstractpub_date
2003-01-01 00:00:00pages
77-80issue
1eissn
0730-725Xissn
1873-5894pii
S0730725X02006252journal_volume
21pub_type
杂志文章abstract::The purpose of this study was to assess the benefits of a 3 T scanner and an eight-channel phased-array head coil for acquiring three-dimensional PRESS (Point REsolved Spectral Selection) proton (H-1) magnetic resonance spectroscopic imaging (MRSI) data from the brains of volunteers and patients with brain tumors rela...
journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(94)00096-l
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journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
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doi:10.1016/j.mri.2007.06.008
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journal_title:Magnetic resonance imaging
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doi:10.1016/s0730-725x(98)00008-3
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doi:10.1016/0730-725x(94)92544-5
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2008.01.013
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journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(93)90214-x
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journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
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journal_title:Magnetic resonance imaging
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