The anion gap in asymptomatic plasma cell dyscrasias.

Abstract:

:The presence of a low anion gap in patients with multiple myeloma has recently been emphasized. This has been related to the retention of chloride and bicarbonate anions to offset the cationic charge of the monoclonal immunoglobulins. We now report the presence of a low anion gap in 50 patients with asymptomatic plasma cell dyscrasias. No correlation was found between the size of the anion gap and the height of the paraprotein "spike" or the size of the anion gap and an index of the net cationic charge of the monoclonal immunoglobulins.

journal_name

Ann Intern Med

authors

Schnur MJ,Appel GB,Karp G,Osserman EP

doi

10.7326/0003-4819-86-3-304

subject

Has Abstract

pub_date

1977-03-01 00:00:00

pages

304-5

issue

3

eissn

0003-4819

issn

1539-3704

journal_volume

86

pub_type

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