Cholesterol reduction and life expectancy. A model incorporating multiple risk factors.

abstract：OBJECTIVE:To determine whether antimicrobial therapy for Helicobacter pylori infection accelerates the healing of duodenal ulcers. DESIGN:Single-blind, randomized, controlled trial. SETTING:Veterans Affairs hospital. PARTICIPANTS:One hundred and five patients with endoscopically verified duodenal ulcers. INTERVENTI...

journal_title：Annals of internal medicine

authors： Graham DY,Lew GM,Evans DG,Evans DJ Jr,Klein PD

更新日期：1991-08-15 00:00:00

abstract：STUDY OBJECTIVE:To determine the effect of a nurse-managed intervention for smoking cessation in patients who have had a myocardial infarction. DESIGN:Randomized, with a 6-month treatment period and a 6-month follow-up. SETTING:Kaiser Foundation hospitals in Redwood City, Santa Clara, Hayward, and San Jose, Californi...

journal_title：Annals of internal medicine

authors： Taylor CB,Houston-Miller N,Killen JD,DeBusk RF

更新日期：1990-07-15 00:00:00

abstract：STUDY OBJECTIVE:To determine the usefulness of the continuous intravenous dexamethasone suppression test in the differential diagnosis of patients with the Cushing syndrome. DESIGN:Comparison of the results of this test with those of other tests in the study population and with data from the literature. SETTING:Refer...

journal_title：Annals of internal medicine

authors： Biemond P,de Jong FH,Lamberts SW

更新日期：1990-05-15 00:00:00

abstract：:In alternative medicine, the main question regarding placebo has been whether a given therapy has more than a placebo effect. Just as mainstream medicine ignores the clinical significance of its own placebo effect, the placebo effect of unconventional medicine is disregarded except for polemics. This essay looks at th...

journal_title：Annals of internal medicine

authors： Kaptchuk TJ

更新日期：2002-06-04 00:00:00

abstract：:Aspirin breaks the gastric mucosal barrier. We studied the effect of aspirin on this barrier, correlating changes in potential difference and ultrastructure. Mean control potential difference for seven subjects was -48 +/- 1.0 mV. Oral aspirin, 600 mg in 100 ml of saline, reduced potential difference to -39 +/- 1.4 mV...

journal_title：Annals of internal medicine

authors： Baskin WN,Ivey KJ,Krause WJ,Jeffrey GE,Gemmell RT

更新日期：1976-09-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the sensitivity of herpes simplex virus isolates to acyclovir and the importance of resistant isolates in hospitalized patients. DESIGN:Retrospective incidence cohort study. SETTING:All herpes simplex virus isolates cultured over 1 year from patients followed at a tertiary care center. P...

journal_title：Annals of internal medicine

authors： Englund JA,Zimmerman ME,Swierkosz EM,Goodman JL,Scholl DR,Balfour HH Jr

更新日期：1990-03-15 00:00:00

abstract：:Doxorubicin (Adriamycin) was administered by continuous infusion to reduce peak plasma levels and thus lessen cardiac toxicity. Cardiotoxicity was monitored by noninvasive methods, and endomyocardial biopsy specimens were studied by electronmicroscopy. Cardiotoxicity was compared in 21 patients receiving doxorubicin i...

journal_title：Annals of internal medicine

authors： Legha SS,Benjamin RS,Mackay B,Ewer M,Wallace S,Valdivieso M,Rasmussen SL,Blumenschein GR,Freireich EJ

更新日期：1982-02-01 00:00:00

abstract：:Adult T-cell leukemia associated with human T-cell leukemia virus type I (HTLV-I) is characterized by a clonal expansion of a CD4-positive subset of T lymphocytes that constitutively express high numbers of interleukin-2 receptors and that frequently infiltrate the skin; osteolytic bone lesions, and hypercalcemia. Usi...

journal_title：Annals of internal medicine

authors： Marcon L,Rubin LA,Kurman CC,Fritz ME,Longo DL,Uchiyama T,Edwards BK,Nelson DL

更新日期：1988-08-15 00:00:00

abstract：BACKGROUND:Each year, millions of patients worldwide have a perioperative myocardial infarction (MI) after noncardiac surgery. OBJECTIVE:To examine the characteristics and short-term outcome of perioperative MI. DESIGN:Cohort study. (ClinicalTrials.gov registration number: NCT00182039) SETTING:190 centers in 23 coun...

journal_title：Annals of internal medicine

authors： Devereaux PJ,Xavier D,Pogue J,Guyatt G,Sigamani A,Garutti I,Leslie K,Rao-Melacini P,Chrolavicius S,Yang H,Macdonald C,Avezum A,Lanthier L,Hu W,Yusuf S,POISE (PeriOperative ISchemic Evaluation) Investigators.

更新日期：2011-04-19 00:00:00

abstract：:Active-control noninferiority trials are being performed with increasing frequency when standard placebo-controlled trials are considered unethical. Three attributes are optimally required to establish noninferiority: 1) The treatment under consideration exhibits therapeutic noninferiority to the active control; 2) th...

journal_title：Annals of internal medicine

authors： Kaul S,Diamond GA

更新日期：2006-07-04 00:00:00

abstract：:Given the low mortality and morbidity of the severe acute respiratory syndrome (SARS) compared with other public health scourges, is the attention devoted to it misdirected? The SARS experience has provided at least 4 enduring lessons. First, by providing a test of the capacity of each part of the public health system...

journal_title：Annals of internal medicine

authors： Emanuel EJ

更新日期：2003-10-07 00:00:00

abstract：OBJECTIVE:To determine whether laboratory findings showing antibodies to hepatitis C virus (HCV) in patients with autoimmune hepatitis represent false-positive results and to identify possible explanations for true-positive results in these patients. DESIGN:Cross-sectional. SETTING:University-based hospital. PATIENT...

journal_title：Annals of internal medicine

authors： Nishiguchi S,Kuroki T,Ueda T,Fukuda K,Takeda T,Nakajima S,Shiomi S,Kobayashi K,Otani S,Hayashi N

更新日期：1992-01-01 00:00:00

abstract：:Polysaccharide vaccines against diseases caused by Neisseria meningitidis serogroups A and C meningococci are now licensed in the United States. They are prepared as monovalent and as bivalent antigens. This statement summarizes available information on these antigen and offers guidance regarding their role in the con...

journal_title：Annals of internal medicine

authors：

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Exercise therapy encompasses a heterogeneous group of interventions. There continues to be uncertainty about the most effective exercise approach in chronic low back pain. PURPOSE:To identify particular exercise intervention characteristics that decrease pain and improve function in adults with nonspecific ...

journal_title：Annals of internal medicine

authors： Hayden JA,van Tulder MW,Tomlinson G

更新日期：2005-05-03 00:00:00

abstract：PURPOSE:To review the electropharmacology, clinical applications, side effects, and hemodynamic profile of intravenous amiodarone. DATA SOURCES:The MEDLINE database was searched for English-language material, including reports of clinical trials and in vivo studies, review articles, and abstracts presented at national...

journal_title：Annals of internal medicine

authors： Desai AD,Chun S,Sung RJ

更新日期：1997-08-15 00:00:00

abstract：:Questionnaire II of the National Study of Internal Medicine Manpower was directed to all of the 1502 subspecialty training programs in the United States and Puerto Rico. The overall response rate was 86%. For the years 1972-1973 through 1976-1977 the number of fellows in subspecialty training grew at an average rate o...

journal_title：Annals of internal medicine

authors： Tarlov AR,Weil PA,Schleiter MK

更新日期：1979-08-01 00:00:00

abstract：:Palliative care prioritizes symptom management and quality of life throughout the course of serious illness. Regardless of whether care is inpatient or outpatient, primary or subspecialty, a solid understanding of the basics of effective communication, symptom management, and end-of-life care is crucial. This article ...

journal_title：Annals of internal medicine

authors： Swetz KM,Kamal AH

更新日期：2018-03-06 00:00:00

abstract：:This statement summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on screening for family and intimate partner violence, based on the USPSTF's examination of evidence specific to family and intimate partner violence, and updates the 1996 recommendations on this topic. In 1996, the USPSTF found...

journal_title：Annals of internal medicine

authors： U. S. Preventive Services Task Force.

更新日期：2004-03-02 00:00:00

abstract：BACKGROUND:The pandemic potential of influenza A (H5N1) virus is a prominent public health concern of the 21st century. OBJECTIVE:To estimate the effectiveness and cost-effectiveness of alternative pandemic (H5N1) mitigation and response strategies. DESIGN:Compartmental epidemic model in conjunction with a Markov mod...

journal_title：Annals of internal medicine

authors： Khazeni N,Hutton DW,Garber AM,Owens DK

更新日期：2009-12-15 00:00:00

abstract：BACKGROUND:The National Kidney Foundation has advocated the use of the abbreviated Modification of Diet in Renal Disease (MDRD) equation to estimate glomerular filtration rate (GFR) from serum creatinine measurements in clinical laboratories. However, healthy persons were not included in the development of the MDRD equ...

journal_title：Annals of internal medicine

authors： Rule AD,Larson TS,Bergstralh EJ,Slezak JM,Jacobsen SJ,Cosio FG

更新日期：2004-12-21 00:00:00

abstract：:Cataract disrupts the crystalline lens, a transparent, elastic, avascular, biconvex structure composed of a capsule, lens epithelium, and lens fiber cells. Many factors contribute to the progression of lens opacity, but aging is most frequently associated with cataract. As aging-related cataract develops, many biochem...

journal_title：Annals of internal medicine

authors： Straatsma BR,Foos RY,Horwitz J,Gardner KM,Pettit TH

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Progress of diabetes care is a subject of public health concern. OBJECTIVE:To assess changes in quality of diabetes care in the United States by using standardized measures. DESIGN:National population-based, serial cross-sectional surveys. SETTING:National Health and Nutrition Examination Survey (1988-199...

journal_title：Annals of internal medicine

authors： Saaddine JB,Cadwell B,Gregg EW,Engelgau MM,Vinicor F,Imperatore G,Narayan KM

更新日期：2006-04-04 00:00:00

abstract：:We report a case of combined idiopathic immune neutropenia and immune thrombocytopenia (thromboneutropenia). Therapy with prednisone was ineffective. Treatment with vincristine raised the patient's platelet count but did not increase the neutrophil count. Splenectomy led to a prompt complete remission. Using radioimmu...

journal_title：Annals of internal medicine

authors： Linker CA,Newcom SR,Nilsson CM,Wolf JL,Shuman MA

更新日期：1980-11-01 00:00:00

abstract：:The traditional exchange of medical expertise between physicians for patient benefit has been accomplished by referral. Physicians have traditionally decided when and to whom to refer patients. Health care "systems" now dominate medical practice, and their formats can alter spontaneous collegial interaction in referra...

journal_title：Annals of internal medicine

authors： Schaffer WA,Holloman FC Jr

更新日期：1985-10-01 00:00:00

abstract：:Twenty-nine men with stage III or unresectable stage II malignant germ cell tumors and no previous chemotherapy received treatments with the VAB-6 protocol. The VAB-6 regimen is a 1-year program beginning with three successive inductions at 3-to-4-week intervals: day 1--cyclophosphamide, 600 mg/m of body surface area ...

journal_title：Annals of internal medicine

authors： Vugrin D,Herr HW,Whitmore WF Jr,Sogani PC,Golbey RB

更新日期：1981-07-01 00:00:00

abstract：:The relation of menopause to cardiovascular disease incidence was examined in women less than 55 years old from the cohort of 2873 women in the initial Framingham examination. Although the number of person-years of experience during the 20 years of observation was nearly the same for premenopausal and postmenopausal s...

journal_title：Annals of internal medicine

authors： Kannel WB,Hjortland MC,McNamara PM,Gordon T

更新日期：1976-10-01 00:00:00

abstract：OBJECTIVE:To compare trimethoprim-sulfamethoxazole (TMP-SMZ) and vancomycin regarding efficacy and safety in the therapy of serious Staphylococcus aureus infections. DESIGN:Randomized, double-blind comparative trial. SETTING:A tertiary-care hospital. PATIENTS:One hundred and one intravenous drug users hospitalized w...

journal_title：Annals of internal medicine

authors： Markowitz N,Quinn EL,Saravolatz LD

更新日期：1992-09-01 00:00:00

abstract：OBJECTIVE:To determine whether concurrent treatment with acetaminophen and zidovudine impairs clearance of zidovudine, thereby increasing the risk for zidovudine-induced hematologic toxicity. DESIGN:Dose escalation, drug interaction study. SETTING:University clinical research center. PATIENTS:Patients with the acqui...

journal_title：Annals of internal medicine

authors： Sattler FR,Ko R,Antoniskis D,Shields M,Cohen J,Nicoloff J,Leedom J,Koda R

更新日期：1991-06-01 00:00:00

abstract：SOURCE CITATION:Ye Z, Rochwerg B, Wang Y, et al. Treatment of patients with nonsevere and severe coronavirus disease 2019: an evidence-based guideline. CMAJ. 2020;192:E536-45. 32350002. ...

journal_title：Annals of internal medicine

authors： Paladugu S,Donato AA

更新日期：2020-07-21 00:00:00

abstract：:The scope of recent literature on the concept of "vulnerable plaque" was reviewed by examining 463 abstracts of primary and review articles identified through MEDLINE (2003 to April 2010). Proposed definition criteria of vulnerable plaque included active inflammation, a thin cap with a large lipid core, endothelial de...

journal_title：Annals of internal medicine

authors： Alsheikh-Ali AA,Kitsios GD,Balk EM,Lau J,Ip S

更新日期：2010-09-21 00:00:00