Reduction of doxorubicin cardiotoxicity by prolonged continuous intravenous infusion.

abstract：:During the last 2 years, the use of pulsed Doppler echocardiography for assessing left ventricular diastolic function has received increased attention. This method is based on measurements derived from a waveform that reflects the velocity of blood flow through the mitral valve during ventricular filling. The techniqu...

journal_title：Annals of internal medicine

authors： Spirito P,Maron BJ

更新日期：1988-07-15 00:00:00

abstract：:Electrophysiologic studies were done in 32 patients with aortic stenosis. In 24 patients with intact A-V conduction, A-H intervals ranged from 55 to 145 msec and were prolonged in two. Two had split His bundle potentials. The H-V intervals ranged from 25 to 94 msec and were prolonged in 12. The mean H-V interval was 6...

journal_title：Annals of internal medicine

authors： Dhingra RC,Amat-y-Leon F,Pietras RJ,Wyndham C,Deedwania PC,Wu D,Denes P,Rosen KM

更新日期：1977-09-01 00:00:00

abstract：:The exocrine pancreas secretes into the gut on demand more than 20 proteins that are indispensable for digestion. In-vivo autodigestion is prevented by an array of natural safeguards. In acute pancreatitis, inappropriate intrapancreatic activation and release of pancreatic hydrolases occur, but the pathogenetic mechan...

journal_title：Annals of internal medicine

authors： Geokas MC,Baltaxe HA,Banks PA,Silva J Jr,Frey CF

更新日期：1985-07-01 00:00:00

abstract：:When cytotoxic agents were introduced, their ability to disrupt nucleic acid and protein synthesis led to their effective use for the treatment of neoplastic disease. During the course of this use, however, it became apparent that these agents also suppress the immune system. This usually unwelcome effect was subseque...

journal_title：Annals of internal medicine

authors： Langford CA,Klippel JH,Balow JE,James SP,Sneller MC

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Life space is a measure of where a person goes, the frequency of going there, and the dependency in getting there. It may be a more accurate measure of mobility in older adults because it reflects participation in society as well as physical ability. OBJECTIVE:To assess effects of hospitalization on life sp...

journal_title：Annals of internal medicine

authors： Brown CJ,Roth DL,Allman RM,Sawyer P,Ritchie CS,Roseman JM

更新日期：2009-03-17 00:00:00

abstract：PURPOSE:To synthesize new data on breast cancer screening for the U.S. Preventive Services Task Force. DATA SOURCES:MEDLINE; the Cochrane Controlled Trials Registry; and reference lists of reviews, editorials, and original studies. STUDY SELECTION:Eight randomized, controlled trials of mammography and 2 trials evalua...

journal_title：Annals of internal medicine

authors： Humphrey LL,Helfand M,Chan BK,Woolf SH

更新日期：2002-09-03 00:00:00

abstract：:Essential trace elements such as zinc, iron, and copper participate in various enzyme reactions directly related to the regulation of blood pressure and indirectly related to generation of oxidative metabolic energy, alterations in blood lipid levels, and alterations in taste acuity. The toxicological action of severa...

journal_title：Annals of internal medicine

authors： Saltman P

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:Tobacco use is the leading cause of preventable death in the United States. PURPOSE:To review the effectiveness and safety of pharmacotherapy and behavioral interventions for tobacco cessation. DATA SOURCES:5 databases and 8 organizational Web sites were searched through 1 August 2014 for systematic review...

journal_title：Annals of internal medicine

authors： Patnode CD,Henderson JT,Thompson JH,Senger CA,Fortmann SP,Whitlock EP

更新日期：2015-10-20 00:00:00

abstract：BACKGROUND:Variants in genes involved in warfarin metabolism and sensitivity affect individual warfarin requirements and the risk for bleeding. Testing for these variant alleles might allow more personalized dosing of warfarin during the induction phase. In 2007, the U.S. Food and Drug Administration changed the labeli...

journal_title：Annals of internal medicine

authors： Eckman MH,Rosand J,Greenberg SM,Gage BF

更新日期：2009-01-20 00:00:00

abstract：BACKGROUND:Few recent data are available on risk factors for perioperative supraventricular arrhythmia (SVA) after noncardiac surgery or on the effect of SVA on clinical outcomes. OBJECTIVE:To determine the incidence, clinical correlates, and effect on length of stay of perioperative SVA in patients having major nonca...

journal_title：Annals of internal medicine

authors： Polanczyk CA,Goldman L,Marcantonio ER,Orav EJ,Lee TH

更新日期：1998-08-15 00:00:00

abstract：:Several trends in medical education affect our supply of future physicians. The number of new physicians has increased so that each year there is an excess of about 6000 over the number of physicians produced per year a decade ago. Increasing numbers of women and members of minority groups are entering the profession ...

journal_title：Annals of internal medicine

authors： Cooper JA

更新日期：1978-11-01 00:00:00

abstract：OBJECTIVE:To examine the relation of obesity and weight loss to the formation of gallstones according to pertinent clinical and research issues. DATA SOURCES AND EXTRACTION:Original reports obtained through a MEDLINE search from 1966 to 1992 on gallstones plus obesity or reducing diets, supplemented by a manual search...

journal_title：Annals of internal medicine

authors： Everhart JE

更新日期：1993-11-15 00:00:00

abstract：Background:In 1994, 40% of U.S. gun owners who had recently acquired a firearm did so without a background check. No contemporary estimates exist. Objective:To estimate the proportion of current U.S. gun owners who acquired their most recent firearm without a background check, by time since and manner of acquisition, ...

journal_title：Annals of internal medicine

authors： Miller M,Hepburn L,Azrael D

更新日期：2017-02-21 00:00:00

abstract：:A prospective pretreatment staging evaluation was done on 49 consecutive patients with mycosis fungoides or the Sézary syndrome to study patterns of disease spread and prognostic factors. Routine staging procedures included complete blood count, blood chemistries, chest roentgenogram, lymphangiogram, radionuclide scan...

journal_title：Annals of internal medicine

authors： Bunn PA Jr,Huberman MS,Whang-Peng J,Schechter GP,Guccion JG,Matthews MJ,Gazdar AF,Dunnick NR,Fischmann AB,Ihde DC,Cohen MH,Fossieck B,Minna JD

更新日期：1980-08-01 00:00:00

abstract：:Recently acquired knowledge about vitamin D metabolism has improved our understanding in different varieties of osteomalacia. Many new causes of osteomalacia continue to be found. Radiologic and biochemical changes are not always characteristic and may occasionally be misleading. Bone biopsy after a double tetracyclin...

journal_title：Annals of internal medicine

authors： Frame B,Parfitt AM

更新日期：1978-12-01 00:00:00

abstract：OBJECTIVE:To document the effects of treatment with famciclovir on the acute signs and symptoms of herpes zoster and postherpetic neuralgia. DESIGN:A randomized, double-blind, placebo-controlled, multicenter trial. SETTING:36 centers in the United States, Canada, and Australia. PATIENTS:419 immunocompetent adults wi...

journal_title：Annals of internal medicine

authors： Tyring S,Barbarash RA,Nahlik JE,Cunningham A,Marley J,Heng M,Jones T,Rea T,Boon R,Saltzman R

更新日期：1995-07-15 00:00:00

abstract：BACKGROUND:Soon, half of all physicians may be married to other physicians (that is, in dual-doctor families). Little is known about how marriage to another physician affects physicians themselves. OBJECTIVE:To learn how physicians in dual-doctor families differ from other physicians in their professional and family l...

journal_title：Annals of internal medicine

authors： Sobecks NW,Justice AC,Hinze S,Chirayath HT,Lasek RJ,Chren MM,Aucott J,Juknialis B,Fortinsky R,Youngner S,Landefeld CS

更新日期：1999-02-16 00:00:00

abstract：BACKGROUND:National guidelines recommend that physicians discuss end-of-life (EOL) care planning with patients with cancer whose life expectancy is less than 1 year. OBJECTIVE:To evaluate the incidence of EOL care discussions for patients with stage IV lung or colorectal cancer and where, when, and with whom these dis...

journal_title：Annals of internal medicine

authors： Mack JW,Cronin A,Taback N,Huskamp HA,Keating NL,Malin JL,Earle CC,Weeks JC

更新日期：2012-02-07 00:00:00

abstract：STUDY OBJECTIVE:To determine the effect of massive cocaine intoxication on lung water and ascites accumulation and the effect of beta- and alpha-adrenergic blockade on survival in massive cocaine intoxication in the mouse. DESIGN:The effect of massive cocaine intoxication on lung water, ascitic fluid accumulation, and...

journal_title：Annals of internal medicine

authors： Robin ED,Wong RJ,Ptashne KA

更新日期：1989-02-01 00:00:00

abstract：:There has been considerable change in the practice of internal medicine in the past quarter century, including the rise of specialization, increasing time pressure, the hospitalist movement, and the rapidly changing responsibilities of internists in inpatient and outpatient settings. Training programs have not adequat...

journal_title：Annals of internal medicine

authors： Association of Program Directors in Internal Medicine.,Fitzgibbons JP,Bordley DR,Berkowitz LR,Miller BW,Henderson MC

更新日期：2006-06-20 00:00:00

abstract：:Lung cancer is the commonest cause of death from cancer in both men and women, with approximately 152,000 new cases and 139,000 deaths in 1988. The incidence and mortality rates are increasing rapidly in women. Two main tests have been used to screen for lung cancer: chest roentgenography and sputum cytology. Four rec...

journal_title：Annals of internal medicine

authors： Eddy DM

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Advice and exercise are widely recommended for subacute low back pain, but the effectiveness of these interventions is unclear. OBJECTIVE:To investigate the effectiveness of physiotherapist-prescribed exercise, advice, or both for subacute low back pain. DESIGN:Factorial randomized, placebo-controlled tria...

journal_title：Annals of internal medicine

authors： Pengel LH,Refshauge KM,Maher CG,Nicholas MK,Herbert RD,McNair P

更新日期：2007-06-05 00:00:00

abstract：:Acute bronchitis is an acute cough illness in otherwise healthy adults that usually lasts 1 to 3 weeks. This review describes the pathophysiology of the condition and provides a practical approach to the evaluation and treatment of adults with uncomplicated acute bronchitis. Practical points to be made are:1. Respirat...

journal_title：Annals of internal medicine

authors： Gonzales R,Sande MA

更新日期：2000-12-19 00:00:00

abstract：:The experience of serving as an expert witness can add considerably to a physician's knowledge of medicine and the forces that affect the profession. Each case compels the physician to examine carefully all the clinical data. The physician must assess the quality of care given and render an opinion that is consistent ...

journal_title：Annals of internal medicine

authors： Kunin CM

更新日期：1984-01-01 00:00:00

abstract：STUDY OBJECTIVE:To define the prevalence, severity, type and pathogenesis of osteopenia in idiopathic hemochromatosis. DESIGN:Prospective study conducted over 18 months. SETTING:Tertiary care center. SUBJECTS:Twenty-two men with idiopathic hemochromatosis and 20 age-matched controls. There were 5 hypogonadal patient...

journal_title：Annals of internal medicine

authors： Diamond T,Stiel D,Posen S

更新日期：1989-03-15 00:00:00

abstract：:Large-scale, epidemic transmission of tuberculosis to patients, nonprofessional staff, nurses, and physicians has been documented recently in hospitals, clinics, acquired immunodeficiency syndrome (AIDS) residencies, and correctional facilities. Prominent factors in these outbreaks have included human immunodeficiency...

journal_title：Annals of internal medicine

authors： Iseman MD

更新日期：1992-08-01 00:00:00

abstract：:The pursuit of the ideal tumor marker has generated many tests for use in the diagnosis and management of cancer, several of which are now widely available. Tumor markers have five potential uses in patient care: They can be used for screening, for diagnosis, for establishing prognosis, for monitoring treatment, and f...

journal_title：Annals of internal medicine

authors： Bates SE

更新日期：1991-10-15 00:00:00

abstract：BACKGROUND:Benign reductions in neutrophil counts may be more common at certain ages and in certain ethnic groups and may be affected by sex and smoking status. OBJECTIVE:To determine differences in neutrophil counts in the U.S. population according to ethnicity, age, sex, and smoking status. DESIGN:Population-based,...

journal_title：Annals of internal medicine

authors： Hsieh MM,Everhart JE,Byrd-Holt DD,Tisdale JF,Rodgers GP

更新日期：2007-04-03 00:00:00

abstract：:After marketing, drugs should be evaluated for safety and for efficacy. Present national systems are inadequate for both tasks. Safety can be evaluated by means of nonexperimental research, whereas evaluation of efficacy in a variety of settings representing normal medical practice generally requires experiments, rand...

journal_title：Annals of internal medicine

authors： Slone D,Shapiro S,Miettinen OS,Finkle WD,Stolley PD

更新日期：1979-02-01 00:00:00

abstract：SOURCE CITATION:Cao B, Wang Y, Wen D, et al. A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19. N Engl J Med. 2020;382:1787-99. 32187464. ...

journal_title：Annals of internal medicine

authors： Yang P,Tekwani S,Martin GS

更新日期：2020-06-16 00:00:00