Clinical applications of serum tumor markers.

abstract：:The experience of serving as an expert witness can add considerably to a physician's knowledge of medicine and the forces that affect the profession. Each case compels the physician to examine carefully all the clinical data. The physician must assess the quality of care given and render an opinion that is consistent ...

journal_title：Annals of internal medicine

authors： Kunin CM

更新日期：1984-01-01 00:00:00

abstract：:A national registry was begun in 1981 to collect data from 32 centers on patients diagnosed by uniform criteria as having primary pulmonary hypertension. Entered into the registry were 187 patients with a mean age (+/- SD) of 36 +/- 15 years (range, 1 to 81), and a female-to-male ratio of 1.7:1 overall. The mean inter...

journal_title：Annals of internal medicine

authors： Rich S,Dantzker DR,Ayres SM,Bergofsky EH,Brundage BH,Detre KM,Fishman AP,Goldring RM,Groves BM,Koerner SK

更新日期：1987-08-01 00:00:00

abstract：:Neuroblastoma, the second commonest solid tumor in children, is a neoplasm of the peripheral autonomic nervous system that usually occurs before children are 6 years old. Therapy of localized tumor (clinical stage I and II) and of a special form of metastatic tumor (clinical stage IV-S) is usually successful, but trea...

journal_title：Annals of internal medicine

authors： Seeger RC,Siegel SE,Sidell N

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:Little evidence exists to support the theory that small-bore nasogastric tubes prevent gastroesophageal reflux and microaspiration in intubated patients. OBJECTIVE:To determine whether gastroesophageal reflux and microaspiration in intubated patients can be reduced by the use of a small-bore nasogastric tub...

journal_title：Annals of internal medicine

authors： Ferrer M,Bauer TT,Torres A,Hernández C,Piera C

更新日期：1999-06-15 00:00:00

abstract：:During the early 1990s, the U.S. government addressed the issue of providing universal health care to all its citizens. Although this issue has not been completely resolved, centralization of electronic data and sharing of health care information among insurers and providers have been pursued. The emergence of electro...

journal_title：Annals of internal medicine

authors： Gostin L

更新日期：1997-10-15 00:00:00

abstract：DESCRIPTION:The American College of Physicians (ACP) developed this guideline to present the available evidence on various pharmacologic treatments to prevent fractures in men and women with low bone density or osteoporosis. METHODS:Published literature on this topic was identified by using MEDLINE (1966 to December 2...

journal_title：Annals of internal medicine

authors： Qaseem A,Snow V,Shekelle P,Hopkins R Jr,Forciea MA,Owens DK,Clinical Efficacy Assessment Subcommittee of the American College of Physicians.

更新日期：2008-09-16 00:00:00

abstract：:The U.S. Preventive Services Task Force (USPSTF) makes recommendations on which preventive services to routinely incorporate into primary care for specific populations. Behavioral counseling interventions are preventive services designed to help persons engage in healthy behaviors and limit unhealthy ones. The USPSTF'...

journal_title：Annals of internal medicine

authors： Curry SJ,Grossman DC,Whitlock EP,Cantu A

更新日期：2014-03-18 00:00:00

abstract：:Under the current system of disability determination and workers' compensation for occupational lung disease, disabled workers or their survivors can reasonably count on being compensated. However, by rejecting established scientific truth in order to pay workers' compensation in circumstances where disability or deat...

journal_title：Annals of internal medicine

authors： Richman SI

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:Few treatments for back pain are supported by strong scientific evidence. Conventional treatments, although widely used, have had limited success. Dissatisfied patients have, therefore, turned to complementary and alternative medical therapies and providers for care for back pain. PURPOSE:To provide a rigor...

journal_title：Annals of internal medicine

authors： Cherkin DC,Sherman KJ,Deyo RA,Shekelle PG

更新日期：2003-06-03 00:00:00

abstract：BACKGROUND:No regulations govern placebo composition. The composition of placebos can influence trial outcomes and merits reporting. PURPOSE:To assess how often investigators specify the composition of placebos in randomized, placebo-controlled trials. DATA SOURCES:4 English-language general and internal medicine jou...

journal_title：Annals of internal medicine

authors： Golomb BA,Erickson LC,Koperski S,Sack D,Enkin M,Howick J

更新日期：2010-10-19 00:00:00

abstract：STUDY OBJECTIVE:To determine the sensitivity of herpes simplex virus isolates to acyclovir and the importance of resistant isolates in hospitalized patients. DESIGN:Retrospective incidence cohort study. SETTING:All herpes simplex virus isolates cultured over 1 year from patients followed at a tertiary care center. P...

journal_title：Annals of internal medicine

authors： Englund JA,Zimmerman ME,Swierkosz EM,Goodman JL,Scholl DR,Balfour HH Jr

更新日期：1990-03-15 00:00:00

abstract：Description:The purpose of this guidance statement is to guide clinicians on colorectal cancer screening in average-risk adults. Methods:This guidance statement is derived from a critical appraisal of guidelines on screening for colorectal cancer in average-risk adults and the evidence presented in these guidelines. N...

journal_title：Annals of internal medicine

authors： Qaseem A,Crandall CJ,Mustafa RA,Hicks LA,Wilt TJ,Clinical Guidelines Committee of the American College of Physicians.

更新日期：2019-11-05 00:00:00

abstract：Background:Triplex vaccine was developed to enhance cytomegalovirus (CMV)-specific T cells and prevent CMV reactivation early after hematopoietic stem cell transplant (HCT). Objective:To determine the safety and efficacy of Triplex. Design:First-in-patient, phase 2 trial. (ClinicalTrials.gov: NCT02506933). Setting:3...

journal_title：Annals of internal medicine

authors： Aldoss I,La Rosa C,Baden LR,Longmate J,Ariza-Heredia EJ,Rida WN,Lingaraju CR,Zhou Q,Martinez J,Kaltcheva T,Dagis A,Hardwick N,Issa NC,Farol L,Nademanee A,Al Malki MM,Forman S,Nakamura R,Diamond DJ,TRIPLEX VACCINE St

更新日期：2020-03-03 00:00:00

abstract：:To re-evaluate the relationship between Crohn's disease and sarcoidosis, we compared the numbers and types of cells recovered by bronchoalveolar lavage from normal volunteers and patients with Crohn's disease, with other forms of inflammatory bowel disease, and with sarcoidosis. Patients with Crohn's disease, but not ...

journal_title：Annals of internal medicine

authors： Smiéjan JM,Cosnes J,Chollet-Martin S,Soler P,Basset FM,Le Quintrec Y,Hance AJ

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Retail clinics are an increasingly popular source for medical care. Concerns have been raised about the effect of these clinics on the cost, quality, and delivery of preventive care. OBJECTIVE:To compare the care received at retail clinics for 3 acute conditions with that received at other care settings. D...

journal_title：Annals of internal medicine

authors： Mehrotra A,Liu H,Adams JL,Wang MC,Lave JR,Thygeson NM,Solberg LI,McGlynn EA

更新日期：2009-09-01 00:00:00

abstract：:To understand the factors that distinguish terminally ill, incompetent patients who are given do-not-resuscitate status by physicians against the wishes of the patient's family, I reviewed the charts of 20 such patients (cases) seen in consultation by the ethics committee at the Massachusetts General Hospital over 10 ...

journal_title：Annals of internal medicine

authors： Brennan TA

更新日期：1988-11-15 00:00:00

abstract：BACKGROUND:Advice and exercise are widely recommended for subacute low back pain, but the effectiveness of these interventions is unclear. OBJECTIVE:To investigate the effectiveness of physiotherapist-prescribed exercise, advice, or both for subacute low back pain. DESIGN:Factorial randomized, placebo-controlled tria...

journal_title：Annals of internal medicine

authors： Pengel LH,Refshauge KM,Maher CG,Nicholas MK,Herbert RD,McNair P

更新日期：2007-06-05 00:00:00

abstract：Background:The 2013 pooled cohort equations (PCEs) are central in prevention guidelines for cardiovascular disease (CVD) but can misestimate CVD risk. Objective:To improve the clinical accuracy of CVD risk prediction by revising the 2013 PCEs using newer data and statistical methods. Design:Derivation and validation ...

journal_title：Annals of internal medicine

authors： Yadlowsky S,Hayward RA,Sussman JB,McClelland RL,Min YI,Basu S

更新日期：2018-07-03 00:00:00

abstract：BACKGROUND:Mounting evidence indicates that subclinical thyroid dysfunction has important clinical effects and prognostic implications, supporting the view that it is not a compensated biochemical change sensu strictu. PURPOSE:To review clinical information on the effects of subclinical thyroid dysfunction on the hear...

journal_title：Annals of internal medicine

authors： Biondi B,Palmieri EA,Lombardi G,Fazio S

更新日期：2002-12-03 00:00:00

abstract：:The presence of a low anion gap in patients with multiple myeloma has recently been emphasized. This has been related to the retention of chloride and bicarbonate anions to offset the cationic charge of the monoclonal immunoglobulins. We now report the presence of a low anion gap in 50 patients with asymptomatic plasm...

journal_title：Annals of internal medicine

authors： Schnur MJ,Appel GB,Karp G,Osserman EP

更新日期：1977-03-01 00:00:00

abstract：STUDY OBJECTIVE:To assess the long-term benefit and side effects of danazol therapy, and to delineate factors influencing the responses in patients with autoimmune thrombocytopenia. DESIGN:Before and after trial. SETTING:Referral-based hematology clinics and the University of Miami teaching hospitals. PATIENTS:Data ...

journal_title：Annals of internal medicine

authors： Ahn YS,Rocha R,Mylvaganam R,Garcia R,Duncan R,Harrington WJ

更新日期：1989-11-01 00:00:00

abstract：:Medical devices have become an integral part of hospital-based care but also predispose patients to more than 850 000 device-related infections annually. Devices predispose to infection by damaging or invading epithelial and mucosal barriers to infection, by supporting growth of microorganisms and thus serving as rese...

journal_title：Annals of internal medicine

authors： Stamm WE

更新日期：1978-11-01 00:00:00

abstract：:Cardiovascular disease is the leading cause of death among women in the United States, and stroke is third. This article uses a case scenario to examine female sex-specific cardiovascular risk factors across the lifespan and describes a precision medicine-based approach to risk factor modification and primary preventi...

journal_title：Annals of internal medicine

authors： Bello NA,Miller EC,Cleary KL,Wapner R

更新日期：2019-12-03 00:00:00

abstract：:Concierge medical practices, which advertise expanded access to care and individualized attention, collect charges both from insurance companies and directly from their patients. Some bill hundreds of dollars for one-time "executive" physicals, whereas others have patients pay annual retainer fees. Yet, virtually no d...

journal_title：Annals of internal medicine

authors： Stillman M

更新日期：2010-03-16 00:00:00

abstract：BACKGROUND:Preeclampsia is a leading cause of maternal and perinatal morbidity and mortality. PURPOSE:To systematically review benefits and harms of low-dose aspirin for preventing morbidity and mortality from preeclampsia. DATA SOURCES:MEDLINE, Database of Abstracts of Reviews of Effects, PubMed, and Cochrane Centra...

journal_title：Annals of internal medicine

authors： Henderson JT,Whitlock EP,O'Connor E,Senger CA,Thompson JH,Rowland MG

更新日期：2014-05-20 00:00:00

abstract：BACKGROUND:The cause of cancer-associated venous limb gangrene is unknown but could paradoxically be due to warfarin. OBJECTIVE:To determine the pathogenesis of venous gangrene in a patient with cancer. DESIGN:Case report. SETTING:University hospital in Ontario, Canada. PATIENT:66-year-old woman with metastatic lun...

journal_title：Annals of internal medicine

authors： Warkentin TE

更新日期：2001-10-16 00:00:00

abstract：BACKGROUND:Apolipoprotein E (apoE) genotypes play critical roles in lipid metabolism and are believed to influence risk for coronary heart disease (CHD). Despite many population studies, however, the impact of apoE polymorphism on risk for CHD remains uncertain. PURPOSE:To qualitatively and quantitatively assess the e...

journal_title：Annals of internal medicine

authors： Song Y,Stampfer MJ,Liu S

更新日期：2004-07-20 00:00:00

abstract：:As the third decade since AIDS was first recognized comes to an end, extraordinary advances have occurred in the understanding, treatment, and prevention of HIV infection and AIDS. As a result of these successes, it is now time to focus on future challenges. Paramount among these is reaching the goal of truly controll...

journal_title：Annals of internal medicine

authors： Dieffenbach CW,Fauci AS

更新日期：2011-06-07 00:00:00

abstract：DESCRIPTION:New recommendation from the U.S. Preventive Services Task Force (USPSTF) on the use of nontraditional, or novel, risk factors in assessing the coronary heart disease (CHD) risk of asymptomatic persons. METHODS:Systematic reviews were conducted of literature since 1996 on 9 proposed nontraditional markers o...

journal_title：Annals of internal medicine

authors： U.S. Preventive Services Task Force.

更新日期：2009-10-06 00:00:00

abstract：BACKGROUND:Indinavir, a protease inhibitor widely used to treat patients with HIV infection, has been associated with nephrolithiasis. Distinctive urinary crystals and a spectrum of urologic disorders were noted in patients receiving indinavir. OBJECTIVE:To determine the composition of urinary crystals and the frequen...

journal_title：Annals of internal medicine

authors： Kopp JB,Miller KD,Mican JA,Feuerstein IM,Vaughan E,Baker C,Pannell LK,Falloon J

更新日期：1997-07-15 00:00:00