What's in placebos: who knows? Analysis of randomized, controlled trials.

abstract：BACKGROUND:Current magnetic resonance techniques generate high signal from venous blood and show thrombi as filling defects. Magnetic resonance direct thrombus imaging (MRDTI) directly visualizes acute thrombus. OBJECTIVE:To determine the accuracy of MRDTI for diagnosis of acute symptomatic deep venous thrombosis (DVT...

journal_title：Annals of internal medicine

authors： Fraser DG,Moody AR,Morgan PS,Martel AL,Davidson I

更新日期：2002-01-15 00:00:00

abstract：:Sideroblastic anemia after treatment for Hogdkin's disease was seen in two patients 3 years after completion of radiation therapy and chemotherapy. This was followed in both by the development of myelomonoblastic leukemia. No evidence of recurrent Hodgkin's disease was present in either patient. Our observation sugges...

journal_title：Annals of internal medicine

authors： Kitahara M,Cosgriff TM,Eyre HJ

更新日期：1980-05-01 00:00:00

abstract：PURPOSE:To evaluate the possibility that fibrinogen represents a cardiovascular risk factor. DATA IDENTIFICATION:A computerized literature search (1980 to 1992) identified all published epidemiologic studies on fibrinogen and cardiovascular disease. Clinical and basic research data were found by separate searches. Ref...

journal_title：Annals of internal medicine

authors： Ernst E,Resch KL

更新日期：1993-06-15 00:00:00

abstract：STUDY OBJECTIVE:To compare single-dose and 10-day treatment regimens of trimethoprim-sulfamethoxazole in women with acute dysuria, urgency, or urinary frequency. DESIGN:Double-blind, randomized, placebo-controlled trial. SETTING:Student health center at a major university. PATIENTS:Consecutive sample of 255 young wo...

journal_title：Annals of internal medicine

authors： Fihn SD,Johnson C,Roberts PL,Running K,Stamm WE

更新日期：1988-03-01 00:00:00

abstract：:Because the cholesterol-rich very low density (VLD) lipoproteins of subjects with type III hyperlipoproteinemia are distinctively enriched in apolipoprotein E, a radial immunodiffusion assay for apolipoprotein E in whole plasma was developed. Its diagnostic usefulness was tested in randomly selected (n = 174) and hype...

journal_title：Annals of internal medicine

authors： Kushwaha RS,Hazzard WR,Wahl PW,Hoover JJ

更新日期：1977-11-01 00:00:00

abstract：:The Residency Program in Social Medicine at Montefiore Medical Center is a collaborative, integrated training program for primary care pediatricians, internists, and family physicians within one interdisciplinary organization. Since 1970 we have trained more than 200 physicians, prepared them for board certification i...

journal_title：Annals of internal medicine

authors： Strelnick AH,Bateman WB,Jones C,Shepherd SD,Massad RJ,Townsend JM,Grossman R,Korin E,Schorow M

更新日期：1988-08-15 00:00:00

abstract：:The association of the Epstein-Barr virus and two human malignancies, Burkitt's lumphoma and nasopharyngeal carcinoma, is reviewed. Seroepidemiologic, virologic, and immunologic evidence is summarized, and several hypotheses regarding a possible etiologic role for the Epstein-Barr virus in these tumors are presented. ...

journal_title：Annals of internal medicine

authors： Ziegler JL,Magrath IT,Gerber P,Levine PH

更新日期：1977-03-01 00:00:00

abstract：BACKGROUND:Impressive decreases in cardiovascular mortality have been achieved through risk factor reduction and clinical intervention, yet cardiovascular disease remains a leading cause of death nationally. OBJECTIVE:To estimate up-to-date preventable fractions of cardiovascular mortality associated with elimination ...

journal_title：Annals of internal medicine

authors： Patel SA,Winkel M,Ali MK,Narayan KM,Mehta NK

更新日期：2015-08-18 00:00:00

abstract：OBJECTIVE:To validate prospectively the use of an artificial neural network to identify myocardial infarction in patients presenting to an emergency department with anterior chest pain. DESIGN:Prospective, blinded testing. SETTING:Tertiary university teaching center. PATIENTS:A total of 331 consecutive adult patient...

journal_title：Annals of internal medicine

authors： Baxt WG

更新日期：1991-12-01 00:00:00

abstract：PURPOSE:To review the current knowledge about breast cancer in black women--including epidemiology, risk factors, screening practices, pathology, clinical manifestations, treatment, and outcome--with emphasis on issues that might explain why the survival rate in this population of women is lower than that in white wome...

journal_title：Annals of internal medicine

authors： Moormeier J

更新日期：1996-05-15 00:00:00

abstract：DESCRIPTION:New U.S. Preventive Services Task Force (USPSTF) recommendation statement on screening for chronic kidney disease (CKD). METHODS:The USPSTF reviewed evidence on screening for CKD, including evidence on screening, accuracy of screening, early treatment, and harms of screening and early treatment. POPULATIO...

journal_title：Annals of internal medicine

authors： Moyer VA,U.S. Preventive Services Task Force.

更新日期：2012-10-16 00:00:00

abstract：BACKGROUND:The risk for and determinants of transmission of tuberculosis in hospitals caring for moderate numbers of patients with tuberculosis remain uncertain. OBJECTIVE:To study the association of tuberculin conversion among health care workers with ventilation of patient care areas. DESIGN:Cross-sectional observa...

journal_title：Annals of internal medicine

authors： Menzies D,Fanning A,Yuan L,FitzGerald JM

更新日期：2000-11-21 00:00:00

abstract：:A controlled clinical trial compared three-drug and four-drug combination chemotherapy in 109 patients with advanced small-cell anaplastic carcinoma of the lung. The combination of vincristine, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU), cyclophosphamide, and methotrexate was significantly superior to the com...

journal_title：Annals of internal medicine

authors： Hansen HH,Dombernowsky P,Hansen M,Hirsch F

更新日期：1978-08-01 00:00:00

abstract：Background:High-sensitivity assays for cardiac troponin T (hs-cTnT) are sometimes used to rapidly rule out acute myocardial infarction (AMI). Purpose:To estimate the ability of a single hs-cTnT concentration below the limit of detection (<0.005 µg/L) and a nonischemic electrocardiogram (ECG) to rule out AMI in adults ...

journal_title：Annals of internal medicine

authors： Pickering JW,Than MP,Cullen L,Aldous S,Ter Avest E,Body R,Carlton EW,Collinson P,Dupuy AM,Ekelund U,Eggers KM,Florkowski CM,Freund Y,George P,Goodacre S,Greenslade JH,Jaffe AS,Lord SJ,Mokhtari A,Mueller C,Munro A

更新日期：2017-05-16 00:00:00

abstract：:The new knowledge of the regulation of cell growth and the genetic and biochemical changes that lead to malignancy have created many new opportunities for cancer drug discovery. These new targets include oncogenes, growth factors and their receptors, signal transduction pathways, and cell differentiation signals. Atte...

journal_title：Annals of internal medicine

authors： Chabner BA

更新日期：1993-04-15 00:00:00

abstract：:Acute bronchitis is an acute cough illness in otherwise healthy adults that usually lasts 1 to 3 weeks. This review describes the pathophysiology of the condition and provides a practical approach to the evaluation and treatment of adults with uncomplicated acute bronchitis. Practical points to be made are:1. Respirat...

journal_title：Annals of internal medicine

authors： Gonzales R,Sande MA

更新日期：2000-12-19 00:00:00

abstract：PURPOSE:Cost-utility analysis is a type of cost-effectiveness analysis in which health effects are measured in terms of quality-adjusted life-years (QALYs) gained. Such analyses have become popular for examining the health and economic consequences of health and medical interventions, and they have been recommended by ...

journal_title：Annals of internal medicine

authors： Neumann PJ,Stone PW,Chapman RH,Sandberg EA,Bell CM

更新日期：2000-06-20 00:00:00

abstract：OBJECTIVE:To critically evaluate the evidence for recommending the screening of asymptomatic men for prostate cancer with a blood test to detect a prostate-specific antigen (PSA). DATA SOURCES:Relevant articles on screening for prostate cancer were identified from MEDLINE searches, from the authors' files, and from th...

journal_title：Annals of internal medicine

authors： Kramer BS,Brown ML,Prorok PC,Potosky AL,Gohagan JK

更新日期：1993-11-01 00:00:00

abstract：:Much time and effort are spent on designing primary research studies. Similar care must be given to planning systematic reviews. The review should be based on an important, well-focused question that is relevant to patient care. By formulating the question properly, the criteria that primary studies must meet to be in...

journal_title：Annals of internal medicine

authors： Counsell C

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:The cause of cancer-associated venous limb gangrene is unknown but could paradoxically be due to warfarin. OBJECTIVE:To determine the pathogenesis of venous gangrene in a patient with cancer. DESIGN:Case report. SETTING:University hospital in Ontario, Canada. PATIENT:66-year-old woman with metastatic lun...

journal_title：Annals of internal medicine

authors： Warkentin TE

更新日期：2001-10-16 00:00:00

abstract：:A patient with familial Mediterranean fever and amyloidosis who received a cadaver renal transplant 6 1/2 years ago was studied to determine the relation of the serum precursor of secondary amyloid (SAA) to the clinical course and to the deposition of amyloid in the transplant. Amyloid fibrils extracted from the patie...

journal_title：Annals of internal medicine

authors： Benson MD,Skinner M,Cohen AS

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND:The Department of Health and Human Services recently called for public comment on human subjects research protections. OBJECTIVE:To assess variability in reviews across institutional review boards (IRBs) for a multisite, minimal-risk trial of financial incentives for evidence-based hypertension care and to ...

journal_title：Annals of internal medicine

authors： Petersen LA,Simpson K,Sorelle R,Urech T,Chitwood SS

更新日期：2012-05-15 00:00:00

abstract：:Cataract disrupts the crystalline lens, a transparent, elastic, avascular, biconvex structure composed of a capsule, lens epithelium, and lens fiber cells. Many factors contribute to the progression of lens opacity, but aging is most frequently associated with cataract. As aging-related cataract develops, many biochem...

journal_title：Annals of internal medicine

authors： Straatsma BR,Foos RY,Horwitz J,Gardner KM,Pettit TH

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:It is unclear whether patients understand that percutaneous coronary intervention (PCI) reduces only chronic stable angina and not myocardial infarction (MI) or associated mortality. OBJECTIVE:To compare cardiologists' and patients' beliefs about PCI. DESIGN:Survey. SETTING:Academic center. PARTICIPANTS:...

journal_title：Annals of internal medicine

authors： Rothberg MB,Sivalingam SK,Ashraf J,Visintainer P,Joelson J,Kleppel R,Vallurupalli N,Schweiger MJ

更新日期：2010-09-07 00:00:00

abstract：:Antinuclear antibodies are present in most patients receiving procainamide. To ascertain whether IgG antiguanosine antibodies are associated with the development of the symptoms of systemic lupus erythematosus, we compared the levels of these antibodies in the sera of 65 patients receiving procainamide: 18 with procai...

journal_title：Annals of internal medicine

authors： Weisbart RH,Yee WS,Colburn KK,Whang SH,Heng MK,Boucek RJ

更新日期：1986-03-01 00:00:00

abstract：:Subacute encephalitis caused by infection of the central nervous system by the human immunodeficiency virus (HIV) is the most frequent cause of neurologic dysfunction in patients with the acquired immunodeficiency syndrome (AIDS). This disorder results in progressive cognitive, motor, and behavioral abnormalities in a...

journal_title：Annals of internal medicine

authors： Gabuzda DH,Hirsch MS

更新日期：1987-09-01 00:00:00

abstract：:Sulfasalazine is metabolized by intestinal bacteria, resulting in the release of sulfapyridine and 5-aminosalicylate. The drug is useful in the treatment of active ulcerative colitis as well as in preventing relapses of the disease in remission. Although effective in active Crohn's disease as well, sulfasalazine appea...

journal_title：Annals of internal medicine

authors： Peppercorn MA

更新日期：1984-09-01 00:00:00

abstract：:Rising health care expenditures have led to numerous cost-control proposals. An examination of the ethical questions surrounding the role that physicians play in the control of health care costs suggests that unilateral rationing decisions by individual physicians at the bedside are morally unacceptable. Such decision...

journal_title：Annals of internal medicine

authors： Sulmasy DP

更新日期：1992-06-01 00:00:00

abstract：STUDY OBJECTIVE:To test the hypothesis that work as a respiratory therapist is associated with an increased risk of developing asthma. DESIGN:Cross-sectional questionnaire study comparing respiratory therapists with controls (physical therapists and radiologic technologists). Subsequent validation of reported asthma w...

journal_title：Annals of internal medicine

authors： Kern DG,Frumkin H

更新日期：1989-05-15 00:00:00

abstract：:Sera of 24 patients with an unexplained pneumonia were tested for the presence of antibodies against the Legionnaires' disease bacterium. Fifteen patients had positive serology. The series comprised 12 male and three female patients ranging in age from 17 to 66 years (mean, 51.1 years). All of the patients had a high ...

journal_title：Annals of internal medicine

authors： Meenhorst PL,van der Meer JW,Borst J

更新日期：1979-04-01 00:00:00