Sulfasalazine. Pharmacology, clinical use, toxicity, and related new drug development.

abstract：OBJECTIVE:To assess the accuracy of Histoplasma capsulatum variety capsulatum polysaccharide antigen testing for the identification of histoplasmosis relapse in patients with the acquired immunodeficiency syndrome (AIDS). DESIGN:A retrospective study using stored specimens. SETTING:A referral center and several priva...

journal_title：Annals of internal medicine

authors： Wheat LJ,Connolly-Stringfield P,Blair R,Connolly K,Garringer T,Katz BP

更新日期：1991-12-15 00:00:00

abstract：BACKGROUND:The long-term risk for fatal pulmonary embolism (PE) after treatment of venous thromboembolism (VTE) may be an important factor in the decision to discontinue this treatment. OBJECTIVE:To provide reliable and precise estimates of the annual risk for fatal PE and the case-fatality rate of disease recurrence ...

journal_title：Annals of internal medicine

authors： Douketis JD,Gu CS,Schulman S,Ghirarduzzi A,Pengo V,Prandoni P

更新日期：2007-12-04 00:00:00

abstract：:The purposes and applications of informed consent are the subject of confusion and controversy according to a President's Commission report. The Commission suggests shared decision making as the new ideal for physician-patient relationships, but notes that such a changed ideal will not be initiated by court action. Th...

journal_title：Annals of internal medicine

authors： Green JA

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Neurologic complications of endocarditis can influence diagnosis, therapeutic plans, and prognosis. OBJECTIVE:To describe how early cerebral magnetic resonance imaging (MRI) affects the diagnosis and management of endocarditis in hospitalized adults. DESIGN:Single-center prospective study between June 2005...

journal_title：Annals of internal medicine

authors： Duval X,Iung B,Klein I,Brochet E,Thabut G,Arnoult F,Lepage L,Laissy JP,Wolff M,Leport C,IMAGE (Resonance Magnetic Imaging at the Acute Phase of Endocarditis) Study Group.

更新日期：2010-04-20 00:00:00

abstract：:Questionnaire II of the National Study of Internal Medicine Manpower was directed to all of the 1502 subspecialty training programs in the United States and Puerto Rico. The overall response rate was 86%. For the years 1972-1973 through 1976-1977 the number of fellows in subspecialty training grew at an average rate o...

journal_title：Annals of internal medicine

authors： Tarlov AR,Weil PA,Schleiter MK

更新日期：1979-08-01 00:00:00

abstract：:Two patients had recurrent facial edema and peripheral blood eosinophilia. One patient showed a marked increase in the serum level of the eosinophil granule major basic protein. In both patients, skin biopsy samples showed nonspecific mononuclear cell inflammation with few eosinophils. However, immunofluorescence stai...

journal_title：Annals of internal medicine

authors： Songsiridej V,Peters MS,Dor PJ,Ackerman SJ,Gleich GJ,Busse WW

更新日期：1985-10-01 00:00:00

abstract：:Type 2 diabetes mellitus is a metabolic disease of carbohydrate metabolism. However, it should also be considered a vascular disease because diabetic patients have a strong predilection for atherosclerosis. With the increasing prevalence and earlier age at onset of diabetes, the projected effect of diabetes on cardiov...

journal_title：Annals of internal medicine

authors： Hurst RT,Lee RW

更新日期：2003-11-18 00:00:00

abstract：BACKGROUND:Health care workers are at occupational risk for a vast array of infections that cause substantial illness and occasional deaths. Despite this, few studies have examined the incidence, prevalence, or exposure-associated rates of infection or have considered infection-specific interventions recommended to mai...

journal_title：Annals of internal medicine

authors： Sepkowitz KA

更新日期：1996-11-15 00:00:00

abstract：:Because the cholesterol-rich very low density (VLD) lipoproteins of subjects with type III hyperlipoproteinemia are distinctively enriched in apolipoprotein E, a radial immunodiffusion assay for apolipoprotein E in whole plasma was developed. Its diagnostic usefulness was tested in randomly selected (n = 174) and hype...

journal_title：Annals of internal medicine

authors： Kushwaha RS,Hazzard WR,Wahl PW,Hoover JJ

更新日期：1977-11-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the efficacy of continuous intravenous infusion of prostacyclin (epoprostenol) in primary pulmonary hypertension. DESIGN:Randomized trial with 8-week treatment periods and nonrandomized treatment for up to 18 months. SETTING:Four referral centers. PATIENTS:Sequential sample of 24 patient...

journal_title：Annals of internal medicine

authors： Rubin LJ,Mendoza J,Hood M,McGoon M,Barst R,Williams WB,Diehl JH,Crow J,Long W

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Pharmaceutical companies and other trial sponsors must submit certain trial results to ClinicalTrials.gov. The validity of these results is unclear. PURPOSE:To validate results posted on ClinicalTrials.gov against publicly available U.S. Food and Drug Administration (FDA) reviews on Drugs@FDA. DATA SOURCES...

journal_title：Annals of internal medicine

authors： Schwartz LM,Woloshin S,Zheng E,Tse T,Zarin DA

更新日期：2016-09-20 00:00:00

abstract：:Aspirin breaks the gastric mucosal barrier. We studied the effect of aspirin on this barrier, correlating changes in potential difference and ultrastructure. Mean control potential difference for seven subjects was -48 +/- 1.0 mV. Oral aspirin, 600 mg in 100 ml of saline, reduced potential difference to -39 +/- 1.4 mV...

journal_title：Annals of internal medicine

authors： Baskin WN,Ivey KJ,Krause WJ,Jeffrey GE,Gemmell RT

更新日期：1976-09-01 00:00:00

abstract：:Position statements opposing legalization of physician-assisted suicide by organizations such as the American College of Physicians-American Society of Internal Medicine rightly emphasize that palliative care should be the standard of care for the dying, and that the inadequacies that exist in its delivery should be r...

journal_title：Annals of internal medicine

authors： Quill TE,Cassel CK

更新日期：2003-02-04 00:00:00

abstract：DESCRIPTION:Reaffirmation of the 2004 U.S. Preventive Services Task Force (USPSTF) recommendation statement on screening for testicular cancer. METHODS:The USPSTF performed a targeted literature search for benefits and harms of screening for testicular cancer in asymptomatic males and found no new studies. RECOMMENDA...

journal_title：Annals of internal medicine

authors： U.S. Preventive Services Task Force.

更新日期：2011-04-05 00:00:00

abstract：:Four hemodialysis patients receiving deferoxamine for metal overload had fatal rhinocerebral rhizopus infections. Serious fungal infections are not commonly seen in patients on dialysis, and none of these patients had the usual risk factors for rhizopus infection. Deferoxamine is being used with increased frequency in...

journal_title：Annals of internal medicine

authors： Windus DW,Stokes TJ,Julian BA,Fenves AZ

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Plasma levels of leptin, the recently discovered satiety hormone, are associated with adiposity in humans. OBJECTIVE:To determine whether genetic factors or body fat distribution affect the association between leptin levels and obesity. PARTICIPANTS:23 healthy identical twin pairs (9 male pairs and 14 fema...

journal_title：Annals of internal medicine

authors： Rönnemaa T,Karonen SL,Rissanen A,Koskenvuo M,Koivisto VA

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:It is currently unknown whether intensive insulin treatment of diabetes decreases the risk for cardiovascular complications by lowering glucose levels or increases the risk by postulated direct atherogenic effects. This article reviews published data from two long-term, randomized clinical trials that compared ...

journal_title：Annals of internal medicine

authors： Genuth S

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Although antiviral therapy is cost-effective in adults, its cost-effectiveness in older adults has not been studied. OBJECTIVE:To determine the cost-effectiveness of influenza testing and treatment strategies for older adults. DESIGN:Cost-utility decision model. DATA SOURCES:Clinical trials of antiviral d...

journal_title：Annals of internal medicine

authors： Rothberg MB,Bellantonio S,Rose DN

更新日期：2003-09-02 00:00:00

abstract：OBJECTIVE:To appraise the measurement properties of the Canadian Cardiovascular Society (CCS) classification of stable angina pectoris. DATA SOURCES:Relevant articles were identified through a MEDLINE search (1976 to November 1991). Bibliographies of retrieved articles were also reviewed. STUDY SELECTION:Studies chos...

journal_title：Annals of internal medicine

authors： Cox J,Naylor CD

更新日期：1992-10-15 00:00:00

abstract：:A case of a patient with metastatic cancer raises the issues of patient refusal of treatment, euthanasia, and unintended side effects of therapy. For each management dilemma, there are relevant ethical and legal considerations, justifications, and conclusions. In addition, psychological and social influences on the de...

journal_title：Annals of internal medicine

authors： Lo B,Jonsen AR

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Timely diagnosis of influenza can help clinical management. PURPOSE:To examine the accuracy of rapid influenza diagnostic tests (RIDTs) in adults and children with influenza-like illness and evaluate factors associated with higher accuracy. DATA SOURCES:PubMed and EMBASE through December 2011; BIOSIS and W...

journal_title：Annals of internal medicine

authors： Chartrand C,Leeflang MM,Minion J,Brewer T,Pai M

更新日期：2012-04-03 00:00:00

abstract：:Thirty-five consecutives patients with classic or definite rheumatoid arthritis underwent echocardiography to evaluate the motion of the anterior mitral valve leaflet. Adequate echocardiograms were obtained in 31 patients. All 31 patients showed normal valve motion and a normal EF slope. If meticulous technique was no...

journal_title：Annals of internal medicine

authors： Davia JE,Cheitlin MD,de Castro CM,Lawless O,Niemi L

更新日期：1975-10-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the usefulness of the continuous intravenous dexamethasone suppression test in the differential diagnosis of patients with the Cushing syndrome. DESIGN:Comparison of the results of this test with those of other tests in the study population and with data from the literature. SETTING:Refer...

journal_title：Annals of internal medicine

authors： Biemond P,de Jong FH,Lamberts SW

更新日期：1990-05-15 00:00:00

abstract：OBJECTIVE:To describe 13 infections caused by Mycobacterium haemophilum. DESIGN:Identification of patients by microbiologic record review, followed by medical record review and a case-control study. SETTING:Seven metropolitan hospitals in New York. PATIENTS:All patients with M. haemophilum infections diagnosed betwe...

journal_title：Annals of internal medicine

authors： Straus WL,Ostroff SM,Jernigan DB,Kiehn TE,Sordillo EM,Armstrong D,Boone N,Schneider N,Kilburn JO,Silcox VA,LaBombardi V,Good RC

更新日期：1994-01-15 00:00:00

abstract：OBJECTIVE:To determine the incidence, cause, and characteristics of pleural effusions in hospitalized patients with the acquired immunodeficiency syndrome (AIDS). DESIGN:Retrospective. PARTICIPANTS:A total of 222 patients with AIDS hospitalized between January 1986 and January 1992 at the Medical University of South ...

journal_title：Annals of internal medicine

authors： Joseph J,Strange C,Sahn SA

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:The optimal strategy to prevent recurrent presumed paradoxical emboli in patients with patent foramen ovale is unknown. PURPOSE:To synthesize the current knowledge about and qualitatively assess the relative benefits of transcatheter closure versus medical therapy for patent foramen ovale. DATA SOURCES:Eng...

journal_title：Annals of internal medicine

authors： Khairy P,O'Donnell CP,Landzberg MJ

更新日期：2003-11-04 00:00:00

abstract：:When cytotoxic agents were introduced, their ability to disrupt nucleic acid and protein synthesis led to their effective use for the treatment of neoplastic disease. During the course of this use, however, it became apparent that these agents also suppress the immune system. This usually unwelcome effect was subseque...

journal_title：Annals of internal medicine

authors： Langford CA,Klippel JH,Balow JE,James SP,Sneller MC

更新日期：1998-07-01 00:00:00

abstract：:Severe hypocalcemia secondary to magnesium depletion has been described in numerous patients with gastrointestinal disorders. The development of profound hypomagnesemia in chronic renal disease is a rare finding. We studied three patients with advanced renal failure and magnesium depletion. Severe hypocalcemia also wa...

journal_title：Annals of internal medicine

authors： Mennes P,Rosenbaum R,Martin K,Slatopolsky E

更新日期：1978-02-01 00:00:00

abstract：:In 1993, the Clinical Efficacy Assessment Subcommittee began evaluation of new topics and reevaluation of previous guidelines on common screening tests, which were published in Annals of Internal Medicine between 1988 and 1990 and republished as a collection in 1991 (Eddy DM, ed. Common Screening Tests. Philadelphia: ...

journal_title：Annals of internal medicine

authors： Littenberg B

更新日期：1995-06-15 00:00:00

abstract：BACKGROUND:Adherence to short-term continuous positive airway pressure (CPAP) may predict long-term use. Unfortunately, initial CPAP intolerance may lead to poor adherence or abandonment of therapy. OBJECTIVE:To determine whether a short course of eszopiclone at the onset of therapy improves long-term CPAP adherence m...

journal_title：Annals of internal medicine

authors： Lettieri CJ,Shah AA,Holley AB,Kelly WF,Chang AS,Roop SA,CPAP Promotion and Prognosis-The Army Sleep Apnea Program Trial.

更新日期：2009-11-17 00:00:00