Ethical decisions in the care of a patient terminally ill with metastatic cancer.

abstract：:Sleep problems are common in pregnant women. This review examines sleep in normal pregnancy; discusses the physiologic bases for alterations in sleep, including hormonal and mechanical factors; and correlates these factors with changes in sleep of pregnant women, as determined subjectively by surveys and objectively b...

journal_title：Annals of internal medicine

authors： Santiago JR,Nolledo MS,Kinzler W,Santiago TV

更新日期：2001-03-06 00:00:00

abstract：:During the past quarter century, general internal medicine has emerged as a vital discipline. In the realm of patient care, it is the integrating discipline par excellence. Ironically, as general internists face the challenge of integrating advances of dizzying speed and complexity, and as their clinical practice beco...

journal_title：Annals of internal medicine

authors： Larson EB

更新日期：2001-05-15 00:00:00

abstract：BACKGROUND:Tobacco use is the leading cause of preventable death in the United States. PURPOSE:To review the effectiveness and safety of pharmacotherapy and behavioral interventions for tobacco cessation. DATA SOURCES:5 databases and 8 organizational Web sites were searched through 1 August 2014 for systematic review...

journal_title：Annals of internal medicine

authors： Patnode CD,Henderson JT,Thompson JH,Senger CA,Fortmann SP,Whitlock EP

更新日期：2015-10-20 00:00:00

abstract：BACKGROUND:Smokers with medical illnesses are at particular risk for complications caused by tobacco. Clinical trial data on the effectiveness of triple-combination pharmacotherapy for tobacco dependence treatment in these high-risk smokers are not available. OBJECTIVE:To evaluate extended duration of a triple-medicat...

journal_title：Annals of internal medicine

authors： Steinberg MB,Greenhaus S,Schmelzer AC,Bover MT,Foulds J,Hoover DR,Carson JL

更新日期：2009-04-07 00:00:00

abstract：:The classification of acute leukemia has almost invariably been based on the morphologic diagnosis into two broad categories: acute lymphocytic and acute myeloid leukemia. Despite the wide range of morphologic variation in both groups, strict criteria to define the subgroups have only recently been proposed. The conve...

journal_title：Annals of internal medicine

authors：

更新日期：1977-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety and efficacy of all-trans retinoic acid to induce complete remission and to examine its effects on duration of remission and survival in patients with acute promyelocytic leukemia. DESIGN:Phase II evaluation and comparison with historical control patients. SETTING:Tertiary care cancer...

journal_title：Annals of internal medicine

authors： Frankel SR,Eardley A,Heller G,Berman E,Miller WH Jr,Dmitrovsky E,Warrell RP Jr

更新日期：1994-02-15 00:00:00

abstract：:Eighteen episodes of community-acquired bacterial pneumonia were diagnosed in 13 patients among 336 with the acquired immunodeficiency syndrome (AIDS) cared for at Memorial Sloan-Kettering Cancer Center since 1979. Bacterial pathogens isolated in 16 of 18 episodes were Haemophilus influenzae in 8, Streptococcus pneumo...

journal_title：Annals of internal medicine

authors： Polsky B,Gold JW,Whimbey E,Dryjanski J,Brown AE,Schiffman G,Armstrong D

更新日期：1986-01-01 00:00:00

abstract：:Eight patients developed grand mal seizures during intravenous theophylline therapy. None had a history of neurologic disorder, and all were acutely ill with severe pulmonary or cardiovascular disease, or both. Serum theophylline concentrations obtained within 1 hour of the seizure ranged from 25 mug/ml to 70mug/ml, w...

journal_title：Annals of internal medicine

authors： Zwillich CW,Sutton FD,Neff TA,Cohn WM,Matthay RA,Weinberger MM

更新日期：1975-06-01 00:00:00

abstract：:Transmission of the human immunodeficiency virus (HIV) was studied in a group of patients with cancer who received transfusion of blood components harvested from a single, asymptomatic, seropositive donor. Of ten living recipients, nine had antibodies to the virus in fresh or cryopreserved sera at a median of 384 days...

journal_title：Annals of internal medicine

authors： Anderson KC,Gorgone BC,Marlink RG,Ferriani R,Essex ME,Benz PM,Groopman JE

更新日期：1986-10-01 00:00:00

abstract：:The competition for funds to conduct clinical research is intense, and only a minority of grant proposals receive funding. In particular, funding for patient-oriented research lags behind that allocated for basic science research. Grant writing is a skill of fundamental importance to the clinical researcher, and condu...

journal_title：Annals of internal medicine

authors： Inouye SK,Fiellin DA

更新日期：2005-02-15 00:00:00

abstract：:Approximately 3000 people in Bennington, Vermont, 19% of the population, had a diarrheal illness during the first and second weeks of June 1978. Persons affected reported abdominal cramps (86%), diarrhea (82%), malaise (73%), and headache (47%). The mean duration of illness was 4.6 days. The illness was associated wit...

journal_title：Annals of internal medicine

authors： Vogt RL,Sours HE,Barrett T,Feldman RA,Dickinson RJ,Witherell L

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:Hospitals are implementing discharge support programs to reduce readmissions, and these programs have had mixed success. OBJECTIVE:To examine whether a peridischarge, nurse-led intervention decreased emergency department (ED) visits or readmissions among ethnically and linguistically diverse older patients ...

journal_title：Annals of internal medicine

authors： Goldman LE,Sarkar U,Kessell E,Guzman D,Schneidermann M,Pierluissi E,Walter B,Vittinghoff E,Critchfield J,Kushel M

更新日期：2014-10-07 00:00:00

abstract：:Anxiety commonly accompanies serious illness. However, in some patients anxiety is the primary manifestation of illness. Diagnostic criteria for these "primary" anxiety disorders have been redefined in the most recent revision of the American Psychiatric Association's Diagnostic and Statistical Manual. We discuss thes...

journal_title：Annals of internal medicine

authors： Brown JT,Mulrow CD,Stoudemire GA

更新日期：1984-04-01 00:00:00

abstract：:In a double-blind study of four patients with hereditary angioedema, the efficacy of methyltestosterone (taken daily in 10-mg linguet form) in preventing attacks was shown. There were 19 episodes during 11.8 months of placebo administration, compared with only four attacks during the 46 months of cumulative methyltest...

journal_title：Annals of internal medicine

authors： Sheffer AL,Fearon DT,Austen KF

更新日期：1977-03-01 00:00:00

abstract：:Two patients with chronic liver disease developed elevated serum aluminum concentrations and biopsy-proven osteodystrophy. Neither patient had chronic renal failure but both had received aluminum-containing antacids for long periods. We measured biliary and urinary aluminum excretion during antacid loading in patients...

journal_title：Annals of internal medicine

authors： Williams JW,Vera SR,Peters TG,Luther RW,Bhattacharya S,Spears H,Graham A,Pitcock JA,Crawford AJ,Palmieri GM

更新日期：1986-06-01 00:00:00

abstract：DESCRIPTION:Update of the 2005 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for peripheral artery disease (PAD). METHODS:The USPSTF reviewed the evidence on the use of resting ankle-brachial index (ABI) as a screening test for PAD or as a risk predictor for cardiovascular disease (CVD). The...

journal_title：Annals of internal medicine

authors： Moyer VA,U.S. Preventive Services Task Force.

更新日期：2013-09-03 00:00:00

abstract：:After decades of silence, the German Society for Internal Medicine (DGIM) has made considerable efforts to come to terms with its role and actions during the Nazi era (1933 to 1945). This is particularly important because, with more than 27 000 members, the DGIM is the largest medical society in present-day Germany. S...

journal_title：Annals of internal medicine

authors： Hofer HG,Forsbach R,Fölsch UR

更新日期：2020-09-01 00:00:00

abstract：:The prevalence of active tuberculosis and positive tuberculin skin tests was assessed in 132 corticosteroid-treated asthmatics for an evaluation period that represented 620 corticosteroid-years of therapy. There was no evidence of active tuberculosis in any of these patients. Positive intermediate-strength tuberculin ...

journal_title：Annals of internal medicine

authors： Schatz M,Patterson R,Kloner R,Falk J

更新日期：1976-03-01 00:00:00

abstract：:Bioethics has become a common course of study in medical schools, other health professional schools, and graduate and undergraduate programs. An analysis of past ethical scandals, as well as the bioethics apparatus that emerged in response to them, is often central to the discussion of bioethical questions. This histo...

journal_title：Annals of internal medicine

authors： Lerner BH,Caplan AL

更新日期：2016-04-19 00:00:00

abstract：:Flecainide acetate has a recognized proarrhythmic effect in patients treated for ventricular tachycardia. Three patients developed severe ventricular arrhythmias while taking flecainide for atrial fibrillation. Patient 1 had normal ventricular function and idiopathic atrial fibrillation. Treadmill exercise tests durin...

journal_title：Annals of internal medicine

authors： Falk RH

更新日期：1989-07-15 00:00:00

abstract：:Antinuclear antibodies are present in most patients receiving procainamide. To ascertain whether IgG antiguanosine antibodies are associated with the development of the symptoms of systemic lupus erythematosus, we compared the levels of these antibodies in the sera of 65 patients receiving procainamide: 18 with procai...

journal_title：Annals of internal medicine

authors： Weisbart RH,Yee WS,Colburn KK,Whang SH,Heng MK,Boucek RJ

更新日期：1986-03-01 00:00:00

abstract：:Sixty-nine out of a kindred of 100 members covering five generations were examined and studied, and 34 were hypercalcemic. Sixteen subjects were believed, on the basis of laboratory and clinical observations, to have primary hyperparathyroidism. Eight patients were subjected to exhaustive study to identify polyendocri...

journal_title：Annals of internal medicine

authors： Goldsmith RE,Sizemore GW,Chen IW,Zalme E,Altemeier WA

更新日期：1976-01-01 00:00:00

abstract：STUDY OBJECTIVE:To assess the effect of weight-bearing exercise training and subsequent detraining on lumbar bone mineral content in postmenopausal women. DESIGN:Non-randomized, controlled, short-term (9 months) trial and long-term (22 months) exercise training and detraining (13 months). SETTING:Section of applied p...

journal_title：Annals of internal medicine

authors： Dalsky GP,Stocke KS,Ehsani AA,Slatopolsky E,Lee WC,Birge SJ Jr

更新日期：1988-06-01 00:00:00

abstract：:In alternative medicine, the main question regarding placebo has been whether a given therapy has more than a placebo effect. Just as mainstream medicine ignores the clinical significance of its own placebo effect, the placebo effect of unconventional medicine is disregarded except for polemics. This essay looks at th...

journal_title：Annals of internal medicine

authors： Kaptchuk TJ

更新日期：2002-06-04 00:00:00

abstract：:We studied D-penicillamine toxicity in 259 patients with systemic sclerosis treated since 1972. The average daily dose of 635 mg was given for a mean of 1.8 years. Of patients with systemic sclerosis, 47% has side effects from D-penicillamine treatment, similar to the 56% of 807 patients with rheumatoid arthritis in s...

journal_title：Annals of internal medicine

authors： Steen VD,Blair S,Medsger TA Jr

更新日期：1986-05-01 00:00:00

abstract：OBJECTIVE:To assess the safety and efficacy of minocycline in the treatment of rheumatoid arthritis. DESIGN:A double-blind, randomized, multicenter, 48-week trial of oral minocycline (200 mg/d) or placebo. SETTING:6 clinical centers in the United States. PATIENTS:219 adults with active rheumatoid arthritis who had p...

journal_title：Annals of internal medicine

authors： Tilley BC,Alarcón GS,Heyse SP,Trentham DE,Neuner R,Kaplan DA,Clegg DO,Leisen JC,Buckley L,Cooper SM,Duncan H,Pillemer SR,Tuttleman M,Fowler SE

更新日期：1995-01-15 00:00:00

abstract：:The following principles of appropriate antibiotic use for adults with acute pharyngitis apply to immunocompetent adults without complicated comorbid conditions, such as chronic lung or heart disease, and history of rheumatic fever. They do not apply during known outbreaks of group A streptococcus.1. Group A beta-hemo...

journal_title：Annals of internal medicine

authors： Cooper RJ,Hoffman JR,Bartlett JG,Besser RE,Gonzales R,Hickner JM,Sande MA,American Academy of Family Physicians.,American College of Physicians-American Society of Internal Medicine.,Centers for Disease Control.

更新日期：2001-03-20 00:00:00

abstract：BACKGROUND:Although clinicians avoid giving meropenem to patients with penicillin allergy because of potential cross-reactivity, the rate of cross-reactivity between penicillins and meropenem has not been prospectively determined. OBJECTIVE:To assess the tolerability of meropenem in patients with documented penicillin...

journal_title：Annals of internal medicine

authors： Romano A,Viola M,Guéant-Rodriguez RM,Gaeta F,Valluzzi R,Guéant JL

更新日期：2007-02-20 00:00:00

abstract：:To assess the course and prognosis of salicylate-induced pulmonary edema, we reviewed the records of 36 consecutive patients admitted with serum salicylate levels greater than 30 mg/dL. Pulmonary edema developed in eight patients, and pulmonary infiltrates were never seen in 28 patients. Several features distinguished...

journal_title：Annals of internal medicine

authors： Heffner JE,Sahn SA

更新日期：1981-10-01 00:00:00

abstract：:Ten patients with lupus nephritis and marked proteinuria (3.9 g or more/d) that did not respond adequately to treatment with prednisone alone or prednisone in combination with azathioprine were treated with total lymphoid irradiation in an uncontrolled feasibility study. Within 6 weeks after the start of total lymphoi...

journal_title：Annals of internal medicine

authors： Strober S,Field E,Hoppe RT,Kotzin BL,Shemesh O,Engleman E,Ross JC,Myers BD

更新日期：1985-04-01 00:00:00