The prevalence of tuberculosis and positive tuberculin skin tests in a steroid-treated asthmatic population.

abstract：:The question of whether initial treatment is necessary in relatively asymptomatic patients with stage III and IV non-Hodgkin's lymphomas of favorable histologic types was studied by retrospective analysis. Two groups of patients were studied: [1] 44 nonprotocol patients, followed since 1963, in whom initial treatment ...

journal_title：Annals of internal medicine

authors： Portlock CS,Rosenberg SA

更新日期：1979-01-01 00:00:00

abstract：:Recent data indicate that the lymphadenopathy-associated virus (LAV) is morphologically similar to animal lentiviruses, such as equine infectious anemia and visna viruses. This finding, together with the cross-reactivity of the core proteins of LAV with those of the equine infectious anemia virus and a similarity in g...

journal_title：Annals of internal medicine

authors： Montagnier L

更新日期：1985-11-01 00:00:00

abstract：:Colony-stimulating factors are growth factors responsible for the proliferation and the maturation of bone marrow stem cells to fully differentiated granulocytes and monocytes. In addition to their effects on hematopoiesis, some colony-stimulating factors prime mature cells for enhanced chemotaxis, phagocytosis, and k...

journal_title：Annals of internal medicine

authors： Weisbart RH,Gasson JC,Golde DW

更新日期：1989-02-15 00:00:00

abstract：BACKGROUND:Prospective data defining the clinical course in idiopathic pulmonary fibrosis (IPF) are sparse. OBJECTIVE:To analyze the clinical course of patients with mild to moderate IPF. DESIGN:Analysis of data from the placebo group of a randomized, controlled trial evaluating interferon-gamma1b. SETTING:Academic ...

journal_title：Annals of internal medicine

authors： Martinez FJ,Safrin S,Weycker D,Starko KM,Bradford WZ,King TE Jr,Flaherty KR,Schwartz DA,Noble PW,Raghu G,Brown KK,IPF Study Group.

更新日期：2005-06-21 00:00:00

abstract：:In an unprecedented approach to viral discovery, the hepatitis C virus (HCV) was cloned before it was established by conventional methods of viral detection or by genomic characterization. Hepatitis C virus is a small (10-kb), single-stranded RNA virus with a genomic organization that places it in the family Flaviviri...

journal_title：Annals of internal medicine

authors： Alter HJ

更新日期：1991-10-15 00:00:00

abstract：:Rising health care expenditures have led to numerous cost-control proposals. An examination of the ethical questions surrounding the role that physicians play in the control of health care costs suggests that unilateral rationing decisions by individual physicians at the bedside are morally unacceptable. Such decision...

journal_title：Annals of internal medicine

authors： Sulmasy DP

更新日期：1992-06-01 00:00:00

abstract：PURPOSE:To review available information on the epidemiology, cause, diagnosis, prognosis, and treatment of acute myocardial infarction during pregnancy or in the early postpartum period and to develop guidelines for the management of this condition. DATA SOURCES:MEDLINE and Index Medicus searches and a manual search o...

journal_title：Annals of internal medicine

authors： Roth A,Elkayam U

更新日期：1996-11-01 00:00:00

abstract：:As more people with mild hypertension are treated, non-drug therapies should be used more frequently and effectively. These therapies include weight reduction; sodium restriction; potassium, calcium, and magnesium supplementation; other dietary changes; exercise; relaxation; and moderation of alcohol use. Such therapi...

journal_title：Annals of internal medicine

authors： Kaplan NM

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:Certain medications are identified by the U.S. Food and Drug Administration (FDA) as class D or X because they increase the risk for birth defects if used during pregnancy. OBJECTIVE:To assess pregnancy rates and the frequency of contraceptive counseling documented with prescriptions for class D or X drugs ...

journal_title：Annals of internal medicine

authors： Schwarz EB,Postlethwaite DA,Hung YY,Armstrong MA

更新日期：2007-09-18 00:00:00

abstract：:Sixty-nine out of a kindred of 100 members covering five generations were examined and studied, and 34 were hypercalcemic. Sixteen subjects were believed, on the basis of laboratory and clinical observations, to have primary hyperparathyroidism. Eight patients were subjected to exhaustive study to identify polyendocri...

journal_title：Annals of internal medicine

authors： Goldsmith RE,Sizemore GW,Chen IW,Zalme E,Altemeier WA

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:U.S. HIV treatment guidelines recommend branded once-daily, 1-pill efavirenz-emtricitabine-tenofovir as first-line antiretroviral therapy (ART). With the anticipated approval of generic efavirenz in the United States, a once-daily, 3-pill alternative (generic efavirenz, generic lamivudine, and tenofovir) wil...

journal_title：Annals of internal medicine

authors： Walensky RP,Sax PE,Nakamura YM,Weinstein MC,Pei PP,Freedberg KA,Paltiel AD,Schackman BR

更新日期：2013-01-15 00:00:00

abstract：BACKGROUND:Staphylococcus aureus is a common cause of serious infection in patients infected with HIV. OBJECTIVES:To evaluate risk factors for and quantitative effect of S. aureus infection in HIV-infected patients, with special attention to nasal carriage. DESIGN:Prospective, multihospital cohort study. SETTING:Thr...

journal_title：Annals of internal medicine

authors： Nguyen MH,Kauffman CA,Goodman RP,Squier C,Arbeit RD,Singh N,Wagener MM,Yu VL

更新日期：1999-02-02 00:00:00

abstract：OBJECTIVE:To assess internists' familiarity with, confidence in, and attitudes about practice guidelines issued by various organizations. DESIGN:Cross-sectional, self-administered survey. PARTICIPANTS:Questionnaires were mailed to a stratified random sample of 2600 members of the American College of Physicians (ACP) ...

journal_title：Annals of internal medicine

authors： Tunis SR,Hayward RS,Wilson MC,Rubin HR,Bass EB,Johnston M,Steinberg EP

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVE:To validate prospectively the use of an artificial neural network to identify myocardial infarction in patients presenting to an emergency department with anterior chest pain. DESIGN:Prospective, blinded testing. SETTING:Tertiary university teaching center. PATIENTS:A total of 331 consecutive adult patient...

journal_title：Annals of internal medicine

authors： Baxt WG

更新日期：1991-12-01 00:00:00

abstract：:Elevated serum digoxin concentrations and clinical toxicity have been reported in patients receiving quinidine. The present study was undertaken to ascertain whether a similar interaction occurs between quinidine and another cardiac glycoside, digitoxin, and if so to evaluate the pharmacokinetic basis in five healthy ...

journal_title：Annals of internal medicine

authors： Garty M,Sood P,Rollins DE

更新日期：1981-01-01 00:00:00

abstract：:As the third decade since AIDS was first recognized comes to an end, extraordinary advances have occurred in the understanding, treatment, and prevention of HIV infection and AIDS. As a result of these successes, it is now time to focus on future challenges. Paramount among these is reaching the goal of truly controll...

journal_title：Annals of internal medicine

authors： Dieffenbach CW,Fauci AS

更新日期：2011-06-07 00:00:00

abstract：OBJECTIVE:To compare trimethoprim-sulfamethoxazole (TMP-SMZ) and vancomycin regarding efficacy and safety in the therapy of serious Staphylococcus aureus infections. DESIGN:Randomized, double-blind comparative trial. SETTING:A tertiary-care hospital. PATIENTS:One hundred and one intravenous drug users hospitalized w...

journal_title：Annals of internal medicine

authors： Markowitz N,Quinn EL,Saravolatz LD

更新日期：1992-09-01 00:00:00

abstract：:During the past quarter century, general internal medicine has emerged as a vital discipline. In the realm of patient care, it is the integrating discipline par excellence. Ironically, as general internists face the challenge of integrating advances of dizzying speed and complexity, and as their clinical practice beco...

journal_title：Annals of internal medicine

authors： Larson EB

更新日期：2001-05-15 00:00:00

abstract：:Antinuclear antibodies are present in most patients receiving procainamide. To ascertain whether IgG antiguanosine antibodies are associated with the development of the symptoms of systemic lupus erythematosus, we compared the levels of these antibodies in the sera of 65 patients receiving procainamide: 18 with procai...

journal_title：Annals of internal medicine

authors： Weisbart RH,Yee WS,Colburn KK,Whang SH,Heng MK,Boucek RJ

更新日期：1986-03-01 00:00:00

abstract：:Some important health policy topics, such as those related to the delivery, organization, and financing of health care, present substantial challenges to established methods for evidence synthesis. For example, such reviews may ask: What is the effect of for-profit versus not-for-profit delivery of care on patient out...

journal_title：Annals of internal medicine

authors： Bravata DM,McDonald KM,Shojania KG,Sundaram V,Owens DK

更新日期：2005-06-21 00:00:00

abstract：:For over 200 years digitalis compounds have been used to treat atrial fibrillation. The rapid ventricular response to atrial fibrillation is frequently treated with digoxin to produce a controlled heart rate. Digoxin has also been proposed as a treatment for terminating recent-onset atrial fibrillation, for maintainin...

journal_title：Annals of internal medicine

authors： Falk RH,Leavitt JI

更新日期：1991-04-01 00:00:00

abstract：:Hypophosphatemic osteomalacia that remits after resection of a coexisting tumor has been described in 35 patients. Because the associated neoplasms have been of mesenchymal origin, it has been inferred that this tumor-induced osteomalacia syndrome is uniquely related to tumours of this derivation. However, in the pres...

journal_title：Annals of internal medicine

authors： Lyles KW,Berry WR,Haussler M,Harrelson JM,Drezner MK

更新日期：1980-08-01 00:00:00

abstract：Background:Many prognostic models for cardiovascular risk can be used to estimate aspirin's absolute benefits, but few bleeding risk models are available to estimate its likely harms. Objective:To develop prognostic bleeding risk models among persons in whom aspirin might be considered for the primary prevention of ca...

journal_title：Annals of internal medicine

authors： Selak V,Jackson R,Poppe K,Wu B,Harwood M,Grey C,Pylypchuk R,Mehta S,Kerr A,Wells S

更新日期：2019-03-19 00:00:00

abstract：OBJECTIVE:To determine the effect of treating Helicobacter pylori infection on the recurrence of gastric and duodenal ulcer disease. DESIGN:Follow-up of up to 2 years in patients with healed ulcers who had participated in randomized, controlled trials. SETTING:A Veterans Affairs hospital. PARTICIPANTS:A total of 109...

journal_title：Annals of internal medicine

authors： Graham DY,Lew GM,Klein PD,Evans DG,Evans DJ Jr,Saeed ZA,Malaty HM

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:The renin-angiotensin system is involved in adipocyte growth and differentiation and possibly in adipose tissue metabolism. OBJECTIVE:To investigate the association of polymorphism in the angiotensin-converting enzyme (ACE) I/D gene, angiotensinogen M235T gene, and angiotensin II type 1 receptor A1166C gene...

journal_title：Annals of internal medicine

authors： Strazzullo P,Iacone R,Iacoviello L,Russo O,Barba G,Russo P,D'Orazio A,Barbato A,Cappuccio FP,Farinaro E,Siani A,Olivetti Prospective Heart Study.

更新日期：2003-01-07 00:00:00

abstract：OBJECTIVE:To determine whether self-assessment of purified protein derivative of tuberculin (PPD) skin test reactions, done using a simple two-choice approach, is an effective screening method for tuberculosis. DESIGN:Double-blind comparison between self-assessments and trained professional readings of PPD skin test r...

journal_title：Annals of internal medicine

authors： Prezant DJ,Kelly KJ,Karwa ML,Kavanagh K

更新日期：1996-08-15 00:00:00

abstract：BACKGROUND:Opioid detoxification in a primary care setting followed by ongoing substance abuse treatment may be appropriate for selected opioid-dependent patients. OBJECTIVE:To compare three pharmacologic protocols for opioid detoxification in a primary care setting. DESIGN:Randomized, double-blind clinical trial wit...

journal_title：Annals of internal medicine

authors： O'Connor PG,Carroll KM,Shi JM,Schottenfeld RS,Kosten TR,Rounsaville BJ

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Hyperuricemia is associated with risk for cardiovascular disease and death. However, the role of uric acid independent of established risk factors is uncertain. OBJECTIVE:To examine the relation of serum uric acid level to incident coronary heart disease, death from cardiovascular disease, and death from al...

journal_title：Annals of internal medicine

authors： Culleton BF,Larson MG,Kannel WB,Levy D

更新日期：1999-07-06 00:00:00

abstract：:Nineteen patients with advanced refractory metastatic breast cancer no longer responsive to chemotherapy were treated in the first phase II efficacy trial of recombinant leukocyte A interferon (IFL-rA), a highly purified single molecular species of alpha interferon prepared by recombinant DNA methods. Patients receive...

journal_title：Annals of internal medicine

authors： Sherwin SA,Mayer D,Ochs JJ,Abrams PG,Knost JA,Foon KA,Fein S,Oldham RK

更新日期：1983-05-01 00:00:00

abstract：OBJECTIVE:To determine risk factors for community-acquired and nosocomial group B streptococcal disease in adults. DESIGN:Case-control study. SETTING:3 metropolitan areas in the United States with an aggregate population of 6.6 million persons. PATIENTS:219 nonpregnant adults with invasive group B streptococcal infe...

journal_title：Annals of internal medicine

authors： Jackson LA,Hilsdon R,Farley MM,Harrison LH,Reingold AL,Plikaytis BD,Wenger JD,Schuchat A

更新日期：1995-09-15 00:00:00