Recombinant leukocyte A interferon in advanced breast cancer. Results of a phase II efficacy trial.

abstract：:In patients with end-stage renal disease, nervous system dysfunction remains a major cause of disability. Patients with chronic renal failure who have not yet received dialysis may have symptoms ranging from mild sensorial clouding to delirium and coma. Dialysis itself is associated with at least three distinct disord...

journal_title：Annals of internal medicine

authors： Fraser CL,Arieff AI

更新日期：1988-07-15 00:00:00

abstract：:Some important health policy topics, such as those related to the delivery, organization, and financing of health care, present substantial challenges to established methods for evidence synthesis. For example, such reviews may ask: What is the effect of for-profit versus not-for-profit delivery of care on patient out...

journal_title：Annals of internal medicine

authors： Bravata DM,McDonald KM,Shojania KG,Sundaram V,Owens DK

更新日期：2005-06-21 00:00:00

abstract：BACKGROUND:Magnetic resonance imaging (MRI) is avoided in most patients with implanted cardiac devices because of safety concerns. OBJECTIVE:To define the safety of a protocol for MRI at the commonly used magnetic strength of 1.5 T in patients with implanted cardiac devices. DESIGN:Prospective nonrandomized trial. (C...

journal_title：Annals of internal medicine

authors： Nazarian S,Hansford R,Roguin A,Goldsher D,Zviman MM,Lardo AC,Caffo BS,Frick KD,Kraut MA,Kamel IR,Calkins H,Berger RD,Bluemke DA,Halperin HR

更新日期：2011-10-04 00:00:00

abstract：BACKGROUND:Ear involvement is not unusual in autoimmune diseases, but few data on this problem in the Sjögren syndrome are available. OBJECTIVES:To determine whether the incidence of hearing loss is increased in patients with the Sjögren syndrome and to determine what factors might be involved in the pathogenesis of S...

journal_title：Annals of internal medicine

authors： Tumiati B,Casoli P,Parmeggiani A

更新日期：1997-03-15 00:00:00

abstract：:Endocarditis is a relatively frequent infection in intravenous drug users. We compared features in the cases of 102 patients with those in intravenous drug users with other causes of fever to identify risk factors predictive of endocarditis. Logistic regression analysis showed cocaine use to be strongly associated wit...

journal_title：Annals of internal medicine

authors： Chambers HF,Morris DL,Täuber MG,Modin G

更新日期：1987-06-01 00:00:00

abstract：:Increased adrenocorticotropic hormone (ACTH) levels after bilateral adrenalectomy could be secondary to a pituitary tumor, under replacement with cortisol, or an abnormality in the hypothalamic-pituitary-adrenal feedback loop. To distinguish between these possibilities, ACTH levels were measured before and after corti...

journal_title：Annals of internal medicine

authors： Koletsky RJ,Dluhy RG,Crantz FR,Williams GH

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:A daily injection of low-molecular-weight heparin (LMWH) is often prescribed to women with unexplained recurrent pregnancy loss (RPL), although evidence suggesting a benefit is questionable. OBJECTIVE:To determine whether LMWH increases ongoing pregnancy and live-birth rates in women with unexplained RPL. ...

journal_title：Annals of internal medicine

authors： Schleussner E,Kamin G,Seliger G,Rogenhofer N,Ebner S,Toth B,Schenk M,Henes M,Bohlmann MK,Fischer T,Brosteanu O,Bauersachs R,Petroff D,ETHIG II group.

更新日期：2015-05-05 00:00:00

abstract：BACKGROUND:The established International Prognostic Index for lymphomas has not included patients with systemic AIDS-related non-Hodgkin lymphoma. OBJECTIVE:To establish the most appropriate prognostic index for use in patients with systemic AIDS-related non-Hodgkin lymphoma. DESIGN:A prospective study involving univ...

journal_title：Annals of internal medicine

authors： Bower M,Gazzard B,Mandalia S,Newsom-Davis T,Thirlwell C,Dhillon T,Young AM,Powles T,Gaya A,Nelson M,Stebbing J

更新日期：2005-08-16 00:00:00

abstract：:Common variable immunodeficiency (CVI) is a heterogenous immunodeficiency syndrome characterized by hypogammaglobulinemia, recurrent bacterial infections, and various immunologic abnormalities. In addition to recurrent infections, patients with this syndrome also have an increased incidence of autoimmune disease and m...

journal_title：Annals of internal medicine

authors： Sneller MC,Strober W,Eisenstein E,Jaffe JS,Cunningham-Rundles C

更新日期：1993-05-01 00:00:00

abstract：:We examined the survival time and costs of therapy for patients with end-stage renal disease. A computer simulation model of the current system was constructed to estimate the cost-effectiveness of home and center hemodialysis and live related as well as cadaver donor renal transplantation. Analysis of the simulation ...

journal_title：Annals of internal medicine

authors： Roberts SD,Maxwell DR,Gross TL

更新日期：1980-02-01 00:00:00

abstract：:A national registry was begun in 1981 to collect data from 32 centers on patients diagnosed by uniform criteria as having primary pulmonary hypertension. Entered into the registry were 187 patients with a mean age (+/- SD) of 36 +/- 15 years (range, 1 to 81), and a female-to-male ratio of 1.7:1 overall. The mean inter...

journal_title：Annals of internal medicine

authors： Rich S,Dantzker DR,Ayres SM,Bergofsky EH,Brundage BH,Detre KM,Fishman AP,Goldring RM,Groves BM,Koerner SK

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Treatment of chronic hepatitis C virus (HCV) infection with direct-acting antivirals (DAAs) for 6 weeks achieves sustained virologic response (SVR) rates of 95% in some patients. If effective, shorter therapeutic courses could improve adherence and treatment costs. OBJECTIVE:To determine factors predictive ...

journal_title：Annals of internal medicine

authors： Kohli A,Kattakuzhy S,Sidharthan S,Nelson A,McLaughlin M,Seamon C,Wilson E,Meissner EG,Sims Z,Silk R,Gross C,Akoth E,Tang L,Price A,Jolley TA,Emmanuel B,Proschan M,Teferi G,Chavez J,Abbott S,Osinusi A,Mo H,Poli

更新日期：2015-12-15 00:00:00

abstract：:We treated 289 men with nongonococcal urethritis in a randomized, double-blind study with minocycline, 100 mg once or twice daily for 7 or 21 days. Ureaplasma urealyticum was isolated before treatment from 167 (58%). The pretherapy isolates from 82 men re-examined 6 to 8 days after initiation of treatment were viable....

journal_title：Annals of internal medicine

authors： Stimson JB,Hale J,Bowie WR,Holmes KK

更新日期：1981-02-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the clinical variables affecting outcome after balloon aortic valvuloplasty. DESIGN:Longitudinal follow-up of consecutive case series. PATIENTS:Consecutive sample of 36 patients with severe calcific aortic stenosis, and without active infection or left ventricular mural thrombus. INTERVE...

journal_title：Annals of internal medicine

authors： Sherman W,Hershman R,Lazzam C,Cohen M,Ambrose J,Gorlin R

更新日期：1989-03-15 00:00:00

abstract：:Streptococcus pneumoniae causes substantial morbidity and mortality. Incidence and severity are increased among populations with some chronic diseases. The currently available polyvalent polysaccharide vaccine induces antibody production among immunologically competent recipients against the 14 serotypes responsible f...

journal_title：Annals of internal medicine

authors： Schwartz JS

更新日期：1982-02-01 00:00:00

abstract：:The efficacy of corticosteroid treatment in the prophylaxis of the fat embolism syndrome was evaluated in a prospective, randomized, double-blind study of high-risk patients with long-bone fractures. Using a set of objective diagnostic criteria, we saw a significant difference in the incidence of the syndrome between ...

journal_title：Annals of internal medicine

authors： Schonfeld SA,Ploysongsang Y,DiLisio R,Crissman JD,Miller E,Hammerschmidt DE,Jacob HS

更新日期：1983-10-01 00:00:00

abstract：:The content, role, and purpose of internal medicine, organized as an American specialty 100 years ago, have been marked by ambivalence from the beginning. Nevertheless, molded to a large extent by external events, including the strategic and symbolic importance of surgery in American medicine, the rise of university m...

journal_title：Annals of internal medicine

authors： Stevens R

更新日期：1986-10-01 00:00:00

abstract：:We studied the clinical and laboratory characteristics of 71 patients with hairy cell leukemia to ascertain whether prognostic factors important for the therapy of the disease existed. Granulocytopenia of less than 500/mu 1 was associated with the occurrence of a serious infection in 46% of the patients, compared to 1...

journal_title：Annals of internal medicine

authors： Golomb HM,Catovsky D,Golde DW

更新日期：1978-11-01 00:00:00

abstract：:One half of 42 subjects treated for painful shoulders received classic acupuncture, and one half received a placebo in which the needles did not penetrate the skin. Half of each of these groups was treated in a positive setting to encourage the subject, and half in a negative setting designed to keep encouragement at ...

journal_title：Annals of internal medicine

authors： Moore ME,Berk SN

更新日期：1976-04-01 00:00:00

abstract：BACKGROUND:Previous research has supported screening for gonorrhea and chlamydia in asymptomatic, sexually active women (including pregnant women) who are younger than 25 years or at increased risk but not in other patient populations. PURPOSE:To update the 2005 and 2007 systematic reviews for the U.S. Preventive Serv...

journal_title：Annals of internal medicine

authors： Zakher B,Cantor AG,Pappas M,Daeges M,Nelson HD

更新日期：2014-12-16 00:00:00

abstract：:For years patients hospitalized with viral hepatitis have been placed in two categories of isolation--enteric precautions and blood precautions. This strategy was based on the inability to differentiate between hepatitis A and B and on the assumption that feces and blood from patients with either type might be infecti...

journal_title：Annals of internal medicine

authors： Favero MS,Maynard JE,Leger RT,Graham DR,Dixon RE

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:Health care-associated infections from invasive medical devices in the intensive care unit (ICU) are a major threat to patient safety. Most published studies of ICU-acquired infections have come from industrialized western countries. In a Centers for Disease Control and Prevention (CDC) National Nosocomial I...

journal_title：Annals of internal medicine

authors： Rosenthal VD,Maki DG,Salomao R,Moreno CA,Mehta Y,Higuera F,Cuellar LE,Arikan OA,Abouqal R,Leblebicioglu H,International Nosocomial Infection Control Consortium.

更新日期：2006-10-17 00:00:00

abstract：:A 53-year-old librarian had recurrent palpable purpura on her ankles and legs that was found to be caused by the fumes released from heat-activated photocopy paper at her place of employment. Behenic acid was identified as the responsible chemical component through a series of challenge studies that simulated her work...

journal_title：Annals of internal medicine

authors： Tencati JR,Novey HS

更新日期：1983-03-01 00:00:00

abstract：:Deficiency of fat-soluble vitamins (A,D,E, and K) was evaluated in 15 patients with exocrine pancreatic insufficiency secondary to chronic alcoholic pancreatitis. Mild to moderate steatorrhea was present in all patients despite oral pancreatic enzyme therapy for 27 +/- 4 months (mean +/- SE). Deficiency of a single fa...

journal_title：Annals of internal medicine

authors： Dutta SK,Bustin MP,Russell RM,Costa BS

更新日期：1982-10-01 00:00:00

abstract：:A recent, widely publicized meta-analysis of 42 clinical trials concluded that rosiglitazone was associated with an approximately 43% increased risk for myocardial infarction and an approximately 64% increased risk for cardiovascular death. The sensitivity of these conclusions to several methodological choices was not...

journal_title：Annals of internal medicine

authors： Diamond GA,Bax L,Kaul S

更新日期：2007-10-16 00:00:00

abstract：BACKGROUND:Each year, millions of patients worldwide have a perioperative myocardial infarction (MI) after noncardiac surgery. OBJECTIVE:To examine the characteristics and short-term outcome of perioperative MI. DESIGN:Cohort study. (ClinicalTrials.gov registration number: NCT00182039) SETTING:190 centers in 23 coun...

journal_title：Annals of internal medicine

authors： Devereaux PJ,Xavier D,Pogue J,Guyatt G,Sigamani A,Garutti I,Leslie K,Rao-Melacini P,Chrolavicius S,Yang H,Macdonald C,Avezum A,Lanthier L,Hu W,Yusuf S,POISE (PeriOperative ISchemic Evaluation) Investigators.

更新日期：2011-04-19 00:00:00

abstract：OBJECTIVE:To evaluate the safety and efficacy of all-trans retinoic acid to induce complete remission and to examine its effects on duration of remission and survival in patients with acute promyelocytic leukemia. DESIGN:Phase II evaluation and comparison with historical control patients. SETTING:Tertiary care cancer...

journal_title：Annals of internal medicine

authors： Frankel SR,Eardley A,Heller G,Berman E,Miller WH Jr,Dmitrovsky E,Warrell RP Jr

更新日期：1994-02-15 00:00:00

abstract：:Aspirin exerts antiplatelet effects through irreversible inhibition of cyclooxygenase-1, whereas its anticancer effects may be due to inhibition of cyclooxygenase-2 and other pathways. In 2009, the U.S. Preventive Services Task Force endorsed aspirin for primary prevention of cardiovascular disease. However, aspirin's...

journal_title：Annals of internal medicine

authors： Burns RB,Graham K,Sawhney MS,Reynolds EE

更新日期：2017-12-05 00:00:00

abstract：BACKGROUND:Although weight loss improves risk factors for cardiovascular and metabolic disease, it is unclear whether intentional weight loss reduces mortality rates. OBJECTIVE:To examine the relationships among intention to lose weight, weight loss, and all-cause mortality. DESIGN:Prospective cohort study using a pr...

journal_title：Annals of internal medicine

authors： Gregg EW,Gerzoff RB,Thompson TJ,Williamson DF

更新日期：2003-03-04 00:00:00

abstract：:Eighteen episodes of community-acquired bacterial pneumonia were diagnosed in 13 patients among 336 with the acquired immunodeficiency syndrome (AIDS) cared for at Memorial Sloan-Kettering Cancer Center since 1979. Bacterial pathogens isolated in 16 of 18 episodes were Haemophilus influenzae in 8, Streptococcus pneumo...

journal_title：Annals of internal medicine

authors： Polsky B,Gold JW,Whimbey E,Dryjanski J,Brown AE,Schiffman G,Armstrong D

更新日期：1986-01-01 00:00:00