Hearing loss in the Sjögren syndrome.

Abstract:

BACKGROUND:Ear involvement is not unusual in autoimmune diseases, but few data on this problem in the Sjögren syndrome are available. OBJECTIVES:To determine whether the incidence of hearing loss is increased in patients with the Sjögren syndrome and to determine what factors might be involved in the pathogenesis of Sjögren syndrome-related hearing loss. DESIGN:Cross-sectional study. SETTING:Secondary referral center in Italy. PATIENTS:30 women with the Sjögren syndrome were evaluated for evidence of audiovestibular disorder. Their results were compared with those of 40 age-matched healthy women. MEASUREMENTS:Evaluation techniques included pure tone audiometry thresholds at octave frequencies of 125 Hz to 8000 Hz, tympanometry, and the stapedial reflex test in both ears. The presence of vasculitis, the Raynaud phenomenon, nervous system involvement, and serum anticardiolipin antibodies was recorded. RESULTS:14 patients with the Sjögren syndrome (46% [95% CI, 28% to 66%]) had sensorineural hearing loss. Only one control (2.5% [CI, 0.06% to 13%]) had a similar hearing impairment (P < 0.001). Nine of the 14 patients who had the Sjögren syndrome and sensorineural hearing loss (64% [CI, 36% to 87%]) had anticardiolipin antibodies compared with only 3 controls (18% [CI, 4% to 45%]) (P = 0.02). CONCLUSION:The high prevalence of hearing loss in the Sjögren syndrome supports the value of doing audiometric studies before excluding cranial nerve involvement in this disease. The correlation of sensorineural hearing loss with anticardiolipin antibodies must be investigated further.

journal_name

Ann Intern Med

authors

Tumiati B,Casoli P,Parmeggiani A

doi

10.7326/0003-4819-126-6-199703150-00005

subject

Has Abstract

pub_date

1997-03-15 00:00:00

pages

450-3

issue

6

eissn

0003-4819

issn

1539-3704

journal_volume

126

pub_type

杂志文章
  • A review of the evidence for the effectiveness, safety, and cost of acupuncture, massage therapy, and spinal manipulation for back pain.

    abstract:BACKGROUND:Few treatments for back pain are supported by strong scientific evidence. Conventional treatments, although widely used, have had limited success. Dissatisfied patients have, therefore, turned to complementary and alternative medical therapies and providers for care for back pain. PURPOSE:To provide a rigor...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-138-11-200306030-00011

    authors: Cherkin DC,Sherman KJ,Deyo RA,Shekelle PG

    更新日期:2003-06-03 00:00:00

  • Good enough: a primer on the analysis and interpretation of noninferiority trials.

    abstract::Active-control noninferiority trials are being performed with increasing frequency when standard placebo-controlled trials are considered unethical. Three attributes are optimally required to establish noninferiority: 1) The treatment under consideration exhibits therapeutic noninferiority to the active control; 2) th...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-145-1-200607040-00011

    authors: Kaul S,Diamond GA

    更新日期:2006-07-04 00:00:00

  • Fibrinogen as a cardiovascular risk factor: a meta-analysis and review of the literature.

    abstract:PURPOSE:To evaluate the possibility that fibrinogen represents a cardiovascular risk factor. DATA IDENTIFICATION:A computerized literature search (1980 to 1992) identified all published epidemiologic studies on fibrinogen and cardiovascular disease. Clinical and basic research data were found by separate searches. Ref...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,meta分析

    doi:10.7326/0003-4819-118-12-199306150-00008

    authors: Ernst E,Resch KL

    更新日期:1993-06-15 00:00:00

  • Dual Receipt of Prescription Opioids From the Department of Veterans Affairs and Medicare Part D and Prescription Opioid Overdose Death Among Veterans: A Nested Case-Control Study.

    abstract:Background:More than half of enrollees in the U.S. Department of Veterans Affairs (VA) are also covered by Medicare and can choose to receive their prescriptions from VA or from Medicare-participating providers. Such dual-system care may lead to unsafe opioid use if providers in these 2 systems do not coordinate care o...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/M18-2574

    authors: Moyo P,Zhao X,Thorpe CT,Thorpe JM,Sileanu FE,Cashy JP,Hale JA,Mor MK,Radomski TR,Donohue JM,Hausmann LRM,Hanlon JT,Good CB,Fine MJ,Gellad WF

    更新日期:2019-04-02 00:00:00

  • Sensitivity of routine clinical criteria for diagnosing myocardial infarction within 24 hours of hospitalization.

    abstract::Myocardial infarction was diagnosed in 431 (30%) of 1460 patients with acute chest pain who had serial enzyme testing after admission to intensive or intermediate care units at three teaching and three community hospitals. The diagnosis was made within 12 hours of admission in 331 (77%) patients and within 24 hours in...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-106-2-181

    authors: Lee TH,Rouan GW,Weisberg MC,Brand DA,Cook EF,Acampora D,Goldman L

    更新日期:1987-02-01 00:00:00

  • Contributions of obesity and weight loss to gallstone disease.

    abstract:OBJECTIVE:To examine the relation of obesity and weight loss to the formation of gallstones according to pertinent clinical and research issues. DATA SOURCES AND EXTRACTION:Original reports obtained through a MEDLINE search from 1966 to 1992 on gallstones plus obesity or reducing diets, supplemented by a manual search...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-119-10-199311150-00010

    authors: Everhart JE

    更新日期:1993-11-15 00:00:00

  • In COVID-19, adding lopinavir-ritonavir to usual care did not shorten time to clinical improvement.

    abstract:SOURCE CITATION:Cao B, Wang Y, Wen D, et al. A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19. N Engl J Med. 2020;382:1787-99. 32187464. ...

    journal_title:Annals of internal medicine

    pub_type: 评论,杂志文章

    doi:10.7326/ACPJ202006160-063

    authors: Yang P,Tekwani S,Martin GS

    更新日期:2020-06-16 00:00:00

  • An evidence-based guide to writing grant proposals for clinical research.

    abstract::The competition for funds to conduct clinical research is intense, and only a minority of grant proposals receive funding. In particular, funding for patient-oriented research lags behind that allocated for basic science research. Grant writing is a skill of fundamental importance to the clinical researcher, and condu...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-142-4-200502150-00009

    authors: Inouye SK,Fiellin DA

    更新日期:2005-02-15 00:00:00

  • Drug regulation in the United States and the United Kingdom: the Depo-Provera story.

    abstract::In 1984, both the United Kingdom and the United States received recommendations from panels of experts specifically convened to consider the merits of Depo-Provera (depot medroxyprogesterone acetate [DMPA]) as a long-term contraceptive agent. This study compares the final reports written by these panels. We explore wh...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-106-6-886

    authors: Richard BW,Lasagna L

    更新日期:1987-06-01 00:00:00

  • Patients' and cardiologists' perceptions of the benefits of percutaneous coronary intervention for stable coronary disease.

    abstract:BACKGROUND:It is unclear whether patients understand that percutaneous coronary intervention (PCI) reduces only chronic stable angina and not myocardial infarction (MI) or associated mortality. OBJECTIVE:To compare cardiologists' and patients' beliefs about PCI. DESIGN:Survey. SETTING:Academic center. PARTICIPANTS:...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-153-5-201009070-00005

    authors: Rothberg MB,Sivalingam SK,Ashraf J,Visintainer P,Joelson J,Kleppel R,Vallurupalli N,Schweiger MJ

    更新日期:2010-09-07 00:00:00

  • Prevention and control of type A influenza infections in nursing homes. Benefits and costs of four approaches using vaccination and amantadine.

    abstract::We developed a model to project morbidity, mortality, and costs attributable to type A influenza virus infections in nursing homes and to evaluate the relative benefits and costs of programs for prevention and control. Influenza vaccination was the most cost-effective intervention under various simulations in the mode...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-107-5-732

    authors: Patriarca PA,Arden NH,Koplan JP,Goodman RA

    更新日期:1987-11-01 00:00:00

  • Postpolypectomy colonoscopy surveillance guidelines: predictive accuracy for advanced adenoma at 4 years.

    abstract:BACKGROUND:Lack of confidence in postpolypectomy surveillance guidelines may be a factor in the observed low adherence rates among providers. OBJECTIVE:To assess the 2006 postpolypectomy colonoscopy surveillance guidelines, which recommend 3-year follow-up colonoscopy for individuals with high-risk adenomas (defined a...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.7326/0003-4819-148-6-200803180-00004

    authors: Laiyemo AO,Murphy G,Albert PS,Sansbury LB,Wang Z,Cross AJ,Marcus PM,Caan B,Marshall JR,Lance P,Paskett ED,Weissfeld J,Slattery ML,Burt R,Iber F,Shike M,Kikendall JW,Lanza E,Schatzkin A

    更新日期:2008-03-18 00:00:00

  • Pneumococcal vaccine: clinical efficacy and effectiveness.

    abstract::Streptococcus pneumoniae causes substantial morbidity and mortality. Incidence and severity are increased among populations with some chronic diseases. The currently available polyvalent polysaccharide vaccine induces antibody production among immunologically competent recipients against the 14 serotypes responsible f...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,评审

    doi:10.7326/0003-4819-96-2-208

    authors: Schwartz JS

    更新日期:1982-02-01 00:00:00

  • Lymphadenopathy-associated virus: from molecular biology to pathogenicity.

    abstract::Recent data indicate that the lymphadenopathy-associated virus (LAV) is morphologically similar to animal lentiviruses, such as equine infectious anemia and visna viruses. This finding, together with the cross-reactivity of the core proteins of LAV with those of the equine infectious anemia virus and a similarity in g...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-103-5-689

    authors: Montagnier L

    更新日期:1985-11-01 00:00:00

  • Documentation and evaluation of cognitive impairment in elderly primary care patients.

    abstract:OBJECTIVE:To describe the prevalence of cognitive impairment among elderly primary care patients and to compare diagnostic evaluations and use of health services among patients with and those without cognitive impairment. DESIGN:Prospective cohort study. SETTING:Academic primary care group practice. PATIENTS:3954 pa...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-122-6-199503150-00004

    authors: Callahan CM,Hendrie HC,Tierney WM

    更新日期:1995-03-15 00:00:00

  • A prognostic index for systemic AIDS-related non-Hodgkin lymphoma treated in the era of highly active antiretroviral therapy.

    abstract:BACKGROUND:The established International Prognostic Index for lymphomas has not included patients with systemic AIDS-related non-Hodgkin lymphoma. OBJECTIVE:To establish the most appropriate prognostic index for use in patients with systemic AIDS-related non-Hodgkin lymphoma. DESIGN:A prospective study involving univ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-143-4-200508160-00007

    authors: Bower M,Gazzard B,Mandalia S,Newsom-Davis T,Thirlwell C,Dhillon T,Young AM,Powles T,Gaya A,Nelson M,Stebbing J

    更新日期:2005-08-16 00:00:00

  • Deficiency of fat-soluble vitamins in treated patients with pancreatic insufficiency.

    abstract::Deficiency of fat-soluble vitamins (A,D,E, and K) was evaluated in 15 patients with exocrine pancreatic insufficiency secondary to chronic alcoholic pancreatitis. Mild to moderate steatorrhea was present in all patients despite oral pancreatic enzyme therapy for 27 +/- 4 months (mean +/- SE). Deficiency of a single fa...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-97-4-549

    authors: Dutta SK,Bustin MP,Russell RM,Costa BS

    更新日期:1982-10-01 00:00:00

  • Screening for peripheral artery disease and cardiovascular disease risk assessment with the ankle-brachial index in adults: U.S. Preventive Services Task Force recommendation statement.

    abstract:DESCRIPTION:Update of the 2005 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for peripheral artery disease (PAD). METHODS:The USPSTF reviewed the evidence on the use of resting ankle-brachial index (ABI) as a screening test for PAD or as a risk predictor for cardiovascular disease (CVD). The...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,实务指引

    doi:10.7326/0003-4819-159-5-201309030-00008

    authors: Moyer VA,U.S. Preventive Services Task Force.

    更新日期:2013-09-03 00:00:00

  • Unrelated donor bone marrow transplantation for chronic myelogenous leukemia: a decision analysis.

    abstract:BACKGROUND:Chronic myelogenous leukemia (CML) is an indolent but ultimately fatal disease. Because the natural history of CML varies and quality of life with CML may be excellent until shortly before death, deciding whether and when to pursue unrelated donor bone marrow transplantation is often difficult. OBJECTIVE:To...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-127-12-199712150-00005

    authors: Lee SJ,Kuntz KM,Horowitz MM,McGlave PB,Goldman JM,Sobocinski KA,Hegland J,Kollman C,Parsons SK,Weinstein MC,Weeks JC,Antin JH

    更新日期:1997-12-15 00:00:00

  • Occupationally acquired infections in health care workers. Part I.

    abstract:BACKGROUND:Health care workers are at occupational risk for a vast array of infections that cause substantial illness and occasional deaths. Despite this, few studies have examined the incidence, prevalence, or exposure-associated rates of infection or have considered infection-specific interventions recommended to mai...

    journal_title:Annals of internal medicine

    pub_type: 历史文章,杂志文章,评审

    doi:10.7326/0003-4819-125-10-199611150-00007

    authors: Sepkowitz KA

    更新日期:1996-11-15 00:00:00

  • Body weight change, all-cause mortality, and cause-specific mortality in the Multiple Risk Factor Intervention Trial.

    abstract:OBJECTIVE:To evaluate the relation between weight variability and death in high-risk, middle-aged men participating in the Multiple Risk Factor Intervention Trial (MRFIT). DESIGN:Cohort study with 3.8 years of follow-up. SETTING:Multicenter, collaborative, primary prevention trial conducted at 22 clinical centers in ...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.7326/0003-4819-119-7_part_2-199310011-00024

    authors: Blair SN,Shaten J,Brownell K,Collins G,Lissner L

    更新日期:1993-10-01 00:00:00

  • Acute postoperative confusion and hallucinations in Parkinson disease.

    abstract:STUDY OBJECTIVE:To determine whether patients with Parkinson disease are at an increased risk for postoperative confusion. DESIGN:Retrospective chart review of patients with Parkinson disease who remained in the hospital at least 48 hours after their surgery. Current data were compared with published historical contro...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-111-3-218

    authors: Golden WE,Lavender RC,Metzer WS

    更新日期:1989-08-01 00:00:00

  • Vitamin-D-resistant osteomalacia in hemodialysis patients lacking secondary hyperparathyroidism.

    abstract::We describe a sporadic, vitamin-D-resistant osteomalacic syndrome in 19 patients undergoing hemodialysis. The syndrome was found in less than 1.5% of patients from referring dialysis centers. All 19 patients had multiple fractures, severe myopathy, and many developed spontaneous hypercalcemia. Severe osteomalacia with...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-94-5-629

    authors: Hodsman AB,Sherrard DJ,Wong EG,Brickman AS,Lee DB,Alfrey AC,Singer FR,Norman AW,Coburn JW

    更新日期:1981-05-01 00:00:00

  • The role of venous ultrasonography in the diagnosis of suspected deep venous thrombosis and pulmonary embolism.

    abstract::This paper describes the role of venous ultrasonography in the diagnosis of suspected deep venous thrombosis and pulmonary embolism. Inability to compress the common femoral or popliteal vein is usually diagnostic of a first episode of deep venous thrombosis in symptomatic patients (positive predictive value of about ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-129-12-199812150-00009

    authors: Kearon C,Ginsberg JS,Hirsh J

    更新日期:1998-12-15 00:00:00

  • Correctional health care: a public health opportunity.

    abstract::The approximately 1.2 million inmates in U.S. correctional institutions have a high prevalence of communicable diseases, such as human immunodeficiency virus (HIV) infection, tuberculosis, hepatitis B virus infection, and gonorrhea. Before their incarceration, most inmates had limited access to health care, which, tog...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-118-2-199301150-00010

    authors: Glaser JB,Greifinger RB

    更新日期:1993-01-15 00:00:00

  • ClinicalTrials.gov and Drugs@FDA: A Comparison of Results Reporting for New Drug Approval Trials.

    abstract:BACKGROUND:Pharmaceutical companies and other trial sponsors must submit certain trial results to ClinicalTrials.gov. The validity of these results is unclear. PURPOSE:To validate results posted on ClinicalTrials.gov against publicly available U.S. Food and Drug Administration (FDA) reviews on Drugs@FDA. DATA SOURCES...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/M15-2658

    authors: Schwartz LM,Woloshin S,Zheng E,Tse T,Zarin DA

    更新日期:2016-09-20 00:00:00

  • The quality of reporting in published cost-utility analyses, 1976-1997.

    abstract:PURPOSE:Cost-utility analysis is a type of cost-effectiveness analysis in which health effects are measured in terms of quality-adjusted life-years (QALYs) gained. Such analyses have become popular for examining the health and economic consequences of health and medical interventions, and they have been recommended by ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-132-12-200006200-00007

    authors: Neumann PJ,Stone PW,Chapman RH,Sandberg EA,Bell CM

    更新日期:2000-06-20 00:00:00

  • The anion gap in asymptomatic plasma cell dyscrasias.

    abstract::The presence of a low anion gap in patients with multiple myeloma has recently been emphasized. This has been related to the retention of chloride and bicarbonate anions to offset the cationic charge of the monoclonal immunoglobulins. We now report the presence of a low anion gap in 50 patients with asymptomatic plasm...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-86-3-304

    authors: Schnur MJ,Appel GB,Karp G,Osserman EP

    更新日期:1977-03-01 00:00:00

  • Systemic lupus erythematosus during penicillamine therapy for rheumatoid arthritis.

    abstract::Six patients with rheumatoid arthritis developed a syndrome resembling lupus erythematosus while being treated with penicillamine. All patients had previous mucocutaneous reactions to chrysotherapy. Manifestations included pleurisy in five of six patients, rashes in three, nephritis in two, and neurologic disturbances...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-97-5-659

    authors: Chalmers A,Thompson D,Stein HE,Reid G,Patterson AC

    更新日期:1982-11-01 00:00:00

  • Solid-phase radioimmunoassay for immunoglobulin G Staphylococcus aureus antibody in serious staphylococcal infection.

    abstract::Clinical features of 99 patients with staphylococcal infection were reviewed, and sera were tested by solid-phase radioimmunoassay and gel diffusion for staphylococcal antibodies to ascertain whether these variables predict the extent of infection and the need for prolonged therapy. Clinical features, including the pr...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-89-4-467

    authors: Wheat LJ,Kohler RB,White A

    更新日期:1978-10-01 00:00:00