The role of venous ultrasonography in the diagnosis of suspected deep venous thrombosis and pulmonary embolism.

abstract：BACKGROUND:Severe aplastic anemia is a life-threatening bone marrow failure disorder. High-dose cyclophosphamide therapy followed by allogeneic bone marrow transplantation cures the disease. However, it requires a suitable donor and carries the risk for graft-versus-host disease. A small pilot study demonstrated that h...

journal_title：Annals of internal medicine

authors： Brodsky RA,Sensenbrenner LL,Smith BD,Dorr D,Seaman PJ,Lee SM,Karp JE,Brodsky I,Jones RJ

更新日期：2001-10-02 00:00:00

abstract：BACKGROUND:Variants in genes involved in warfarin metabolism and sensitivity affect individual warfarin requirements and the risk for bleeding. Testing for these variant alleles might allow more personalized dosing of warfarin during the induction phase. In 2007, the U.S. Food and Drug Administration changed the labeli...

journal_title：Annals of internal medicine

authors： Eckman MH,Rosand J,Greenberg SM,Gage BF

更新日期：2009-01-20 00:00:00

abstract：:Pemphigus is an autoimmune intraepidermal bullous disease involving the skin and mucous membranes. There are four clinically recognized variants of this disease. The histopathologic hallmark is acantholysis, which is disruption of normal cell-to-cell adhesion. Patients produce an IgG antibody directed against an antig...

journal_title：Annals of internal medicine

authors：

更新日期：1980-03-01 00:00:00

abstract：OBJECTIVE:To describe the clinical, laboratory, and echocardiographic findings in a large group of patients with right-sided endocarditis and to determine whether any of these findings is predictive of prognosis. DESIGN:Retrospective survey of medical records to evaluate the course of hospitalization with follow-up on...

journal_title：Annals of internal medicine

authors： Hecht SR,Berger M

更新日期：1992-10-01 00:00:00

abstract：:Aspirin breaks the gastric mucosal barrier. We studied the effect of aspirin on this barrier, correlating changes in potential difference and ultrastructure. Mean control potential difference for seven subjects was -48 +/- 1.0 mV. Oral aspirin, 600 mg in 100 ml of saline, reduced potential difference to -39 +/- 1.4 mV...

journal_title：Annals of internal medicine

authors： Baskin WN,Ivey KJ,Krause WJ,Jeffrey GE,Gemmell RT

更新日期：1976-09-01 00:00:00

abstract：:Electrophysiologic studies were done in 32 patients with aortic stenosis. In 24 patients with intact A-V conduction, A-H intervals ranged from 55 to 145 msec and were prolonged in two. Two had split His bundle potentials. The H-V intervals ranged from 25 to 94 msec and were prolonged in 12. The mean H-V interval was 6...

journal_title：Annals of internal medicine

authors： Dhingra RC,Amat-y-Leon F,Pietras RJ,Wyndham C,Deedwania PC,Wu D,Denes P,Rosen KM

更新日期：1977-09-01 00:00:00

abstract：:The data from population-based, randomized trials of the mammographic screening of women aged 40 to 49 years are limited by retrospective subgroup analysis, low statistical power, and the use of older mammographic techniques. Nonetheless, meta-analysis involving the most recently reported data from all similarly desig...

journal_title：Annals of internal medicine

authors： Sickles EA,Kopans DB

更新日期：1995-04-01 00:00:00

abstract：:Two patients presented with abnormalities suggestive of pituitary adenoma; one during pregnancy and one in the postpartum period. However, pathologic examination of the pituitary showed extensive destruction by a lymphoplasmacytic infiltrate; no tumor was identified. Both patients developed hypopituitarism. We know of...

journal_title：Annals of internal medicine

authors： Asa SL,Bilbao JM,Kovacs K,Josse RG,Kreines K

更新日期：1981-08-01 00:00:00

abstract：OBJECTIVE:To measure changes in spinal and femoral neck bone mineral densities in patients treated for Graves thyrotoxicosis. DESIGN:Cohort study. SETTING:Tertiary care center. PATIENTS:Fifteen women with active Graves thyrotoxicosis. Six patients were premenopausal and nine were postmenopausal. All patients had evi...

journal_title：Annals of internal medicine

authors： Diamond T,Vine J,Smart R,Butler P

更新日期：1994-01-01 00:00:00

abstract：:Infection with human immunodeficiency virus (HIV) may cause viral antigenemia, detected primarily as p24 viral core protein. Among 16 patients with the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex studied serially, 12 had or developed antigenemia ranging from 16 to 3006 pg/mL in plasma. The level ...

journal_title：Annals of internal medicine

authors： Jackson GG,Paul DA,Falk LA,Rubenis M,Despotes JC,Mack D,Knigge M,Emeson EE

更新日期：1988-02-01 00:00:00

abstract：:For years patients hospitalized with viral hepatitis have been placed in two categories of isolation--enteric precautions and blood precautions. This strategy was based on the inability to differentiate between hepatitis A and B and on the assumption that feces and blood from patients with either type might be infecti...

journal_title：Annals of internal medicine

authors： Favero MS,Maynard JE,Leger RT,Graham DR,Dixon RE

更新日期：1979-12-01 00:00:00

abstract：OBJECTIVE:To determine whether laboratory findings showing antibodies to hepatitis C virus (HCV) in patients with autoimmune hepatitis represent false-positive results and to identify possible explanations for true-positive results in these patients. DESIGN:Cross-sectional. SETTING:University-based hospital. PATIENT...

journal_title：Annals of internal medicine

authors： Nishiguchi S,Kuroki T,Ueda T,Fukuda K,Takeda T,Nakajima S,Shiomi S,Kobayashi K,Otani S,Hayashi N

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To estimate relative risk of mortality and median life expectancy for patients with classic hemophilia by a life-table analysis, taking into account deaths that may have occurred in infancy or childhood before the onset of symptoms. DESIGN:Retrospective chart review of clinical series. SETTING:Referral-base...

journal_title：Annals of internal medicine

authors： Jones PK,Ratnoff OD

更新日期：1991-04-15 00:00:00

abstract：PURPOSE:To examine the cost-effectiveness of test-treatment strategies for patients suspected of having Lyme disease. DATA SOURCES:The medical literature was searched for information on outcomes and costs. Expert opinion was sought for information on utilities. STUDY SELECTION:Articles that described patient populati...

journal_title：Annals of internal medicine

authors： Nichol G,Dennis DT,Steere AC,Lightfoot R,Wells G,Shea B,Tugwell P

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Cardiovascular disease (CVD) is the leading cause of death in the United States. PURPOSE:To update a systematic review about the benefits of aspirin for the primary prevention of cardiovascular events in adults aged 40 years or older and to evaluate effect modification in subpopulations. DATA SOURCES:MEDLI...

journal_title：Annals of internal medicine

authors： Guirguis-Blake JM,Evans CV,Senger CA,O'Connor EA,Whitlock EP

更新日期：2016-06-21 00:00:00

abstract：:Type 2 diabetes mellitus is a metabolic disease of carbohydrate metabolism. However, it should also be considered a vascular disease because diabetic patients have a strong predilection for atherosclerosis. With the increasing prevalence and earlier age at onset of diabetes, the projected effect of diabetes on cardiov...

journal_title：Annals of internal medicine

authors： Hurst RT,Lee RW

更新日期：2003-11-18 00:00:00

abstract：:Hearing loss is highly prevalent and may significantly affect how we age. Although the population is aging, relatively few adults receive treatment for hearing loss. Internists are a critical partner to audiologists and otolaryngologists in caring for the adult population with hearing loss. This review provides a prim...

journal_title：Annals of internal medicine

authors： Nieman CL,Oh ES

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Short-term aspirin therapy can lower the risk for venous thromboembolism (VTE) in high-risk patients, but whether the long-term use of low-dose aspirin reduces risk in healthy adults is uncertain. OBJECTIVE:To test the efficacy of long-term aspirin therapy for preventing VTE. DESIGN:Secondary analysis of a...

journal_title：Annals of internal medicine

authors： Glynn RJ,Ridker PM,Goldhaber SZ,Buring JE

更新日期：2007-10-16 00:00:00

abstract：BACKGROUND:It is unclear whether patients understand that percutaneous coronary intervention (PCI) reduces only chronic stable angina and not myocardial infarction (MI) or associated mortality. OBJECTIVE:To compare cardiologists' and patients' beliefs about PCI. DESIGN:Survey. SETTING:Academic center. PARTICIPANTS:...

journal_title：Annals of internal medicine

authors： Rothberg MB,Sivalingam SK,Ashraf J,Visintainer P,Joelson J,Kleppel R,Vallurupalli N,Schweiger MJ

更新日期：2010-09-07 00:00:00

abstract：:Deaths and injuries related to firearms constitute a major public health problem in the United States. In response to firearm violence and other firearm-related injuries and deaths, an interdisciplinary, interprofessional group of leaders of 8 national health professional organizations and the American Bar Association...

journal_title：Annals of internal medicine

authors： Weinberger SE,Hoyt DB,Lawrence HC 3rd,Levin S,Henley DE,Alden ER,Wilkerson D,Benjamin GC,Hubbard WC

更新日期：2015-04-07 00:00:00

abstract：:Asthma is characterized by inflammation, reversible airway obstruction, and increased airway responsiveness to various stimuli. It has received wide public attention in recent years because of increasing morbidity and deaths, particularly among black persons. The important role of inflammation in the immunopathogenesi...

journal_title：Annals of internal medicine

authors： Goldstein RA,Paul WE,Metcalfe DD,Busse WW,Reece ER

更新日期：1994-11-01 00:00:00

abstract：:Hypophosphatemic osteomalacia that remits after resection of a coexisting tumor has been described in 35 patients. Because the associated neoplasms have been of mesenchymal origin, it has been inferred that this tumor-induced osteomalacia syndrome is uniquely related to tumours of this derivation. However, in the pres...

journal_title：Annals of internal medicine

authors： Lyles KW,Berry WR,Haussler M,Harrelson JM,Drezner MK

更新日期：1980-08-01 00:00:00

abstract：:A group of 44 homosexual patients with immune thrombocytopenia and serologic evidence of infection with the human immunodeficiency virus (HIV) was observed for a total of 844 person-months. The risk of developing the acquired immunodeficiency syndrome (AIDS), an actuarial incidence of 36.5% in 37 months, was no differ...

journal_title：Annals of internal medicine

authors： Holzman RS,Walsh CM,Karpatkin S

更新日期：1987-03-01 00:00:00

abstract：:Cardiovascular disease is the leading cause of death among women in the United States, and stroke is third. This article uses a case scenario to examine female sex-specific cardiovascular risk factors across the lifespan and describes a precision medicine-based approach to risk factor modification and primary preventi...

journal_title：Annals of internal medicine

authors： Bello NA,Miller EC,Cleary KL,Wapner R

更新日期：2019-12-03 00:00:00

abstract：:Fifteen patients with chronic type B hepatitis were treated with corticosteroids in a randomized, double-blind, placebo-controlled trial lasting 28 days. Ten patients received prednisolone, 60 mg/d for 2 weeks, then 30 mg/d for another 2 weeks; 5 patients received placebo. Serum aminotransferase levels decreased signi...

journal_title：Annals of internal medicine

authors： Hoofnagle JH,Davis GL,Pappas SC,Hanson RG,Peters M,Avigan MI,Waggoner JG,Jones EA,Seeff LB

更新日期：1986-01-01 00:00:00

abstract：:During a 4.4-year period, nonspecific interstitial pneumonitis was seen in 41 of 110 (38%) patients with the acquired immunodeficiency syndrome and accounted for 32% (48/152) of all episodes of clinical pneumonitis. Diffuse alveolar damage was typically a feature of nonspecific interstitial pneumonitis, but neither lu...

journal_title：Annals of internal medicine

authors： Suffredini AF,Ognibene FP,Lack EE,Simmons JT,Brenner M,Gill VJ,Lane HC,Fauci AS,Parrillo JE,Masur H

更新日期：1987-07-01 00:00:00

abstract：:Glomerular-fixed antibody was eluted from the kidney of a 17-year-old patient who died 2 weeks after the onset of acute poststreptococcal glomerulonephritis. Elevated titers of antibodies to streptococcal enzymes were found in the serum but not in the glomerular eluate. Streptococcal M protein and anti-M protein react...

journal_title：Annals of internal medicine

authors： Rodríguez-Iturbe B,Rabideau D,García R,Rubio L,McIntosh RM

更新日期：1980-04-01 00:00:00

abstract：:Patients with variant angina refractory to medical therapy pose a difficult management problem. We report two patients with variant angina who had focal spasm in coronary arteries with fixed obstructions of less than 20% of the luminal diameter. Ischemic episodes were accompanied by malignant ventricular arrhythmias a...

journal_title：Annals of internal medicine

authors： Sussman EJ,Goldberg S,Poll DS,MacVaugh H 3rd,Simson MB,Silber SA,Kastor JA

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND:Several studies show an inverse association between self-reported physical activity and type 2 diabetes. It is not known whether physical activity or cardiorespiratory fitness is associated with the onset of objectively determined impaired fasting glucose and type 2 diabetes. OBJECTIVE:To determine whether ...

journal_title：Annals of internal medicine

authors： Wei M,Gibbons LW,Mitchell TL,Kampert JB,Lee CD,Blair SN

更新日期：1999-01-19 00:00:00

abstract：BACKGROUND:Tobacco dependence is a chronic, relapsing condition that may require extended treatment. OBJECTIVE:To assess whether extended-duration transdermal nicotine therapy increases abstinence from tobacco more than standard-duration therapy in adult smokers. DESIGN:Parallel randomized, placebo-controlled trial f...

journal_title：Annals of internal medicine

authors： Schnoll RA,Patterson F,Wileyto EP,Heitjan DF,Shields AE,Asch DA,Lerman C

更新日期：2010-02-02 00:00:00