Deficiency of fat-soluble vitamins in treated patients with pancreatic insufficiency.

Abstract:

:Deficiency of fat-soluble vitamins (A,D,E, and K) was evaluated in 15 patients with exocrine pancreatic insufficiency secondary to chronic alcoholic pancreatitis. Mild to moderate steatorrhea was present in all patients despite oral pancreatic enzyme therapy for 27 +/- 4 months (mean +/- SE). Deficiency of a single fat-soluble vitamin was seen in six patients and deficiency of two fat-soluble vitamins was seen in two patients. One patient was deficient in three fat-soluble vitamins. Deficiency of vitamins A and E was most frequent. Treatment with specific vitamin supplements resulted in correction of these vitamin deficiencies. These data suggest that deficiency of a single or multiple fat-soluble vitamins is frequent even in treated patients with pancreatic insufficiency.

journal_name

Ann Intern Med

authors

Dutta SK,Bustin MP,Russell RM,Costa BS

doi

10.7326/0003-4819-97-4-549

subject

Has Abstract

pub_date

1982-10-01 00:00:00

pages

549-52

issue

4

eissn

0003-4819

issn

1539-3704

journal_volume

97

pub_type

杂志文章
  • Trends in the incidence of venous thromboembolism during pregnancy or postpartum: a 30-year population-based study.

    abstract:BACKGROUND:The risk for venous thromboembolism during pregnancy or postpartum is uncertain. OBJECTIVES:To estimate the relative and absolute risk for deep venous thrombosis and pulmonary embolism during pregnancy and postpartum and to describe trends in incidence. DESIGN:Population-based inception cohort study using ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-143-10-200511150-00006

    authors: Heit JA,Kobbervig CE,James AH,Petterson TM,Bailey KR,Melton LJ 3rd

    更新日期:2005-11-15 00:00:00

  • The frequency of lupus anticoagulant in systemic lupus erythematosus. A study of sixty consecutive patients by activated partial thromboplastin time, Russell viper venom time, and anticardiolipin antibody level.

    abstract::Recent reviews have suggested a higher frequency of the lupus anticoagulant or related antiphospholipid antibodies in patients with systemic lupus erythematosus (21% to 65%) than was found in earlier studies (6% to 18%). In our study of 60 consecutive patients, we found the frequency of the lupus anticoagulant by Russ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-106-4-524

    authors: Petri M,Rheinschmidt M,Whiting-O'Keefe Q,Hellmann D,Corash L

    更新日期:1987-04-01 00:00:00

  • Pharmacologic therapy for type 2 diabetes mellitus.

    abstract::Type 2 diabetes mellitus is a chronic metabolic disorder that results from defects in both insulin secretion and insulin action. An elevated rate of basal hepatic glucose production in the presence of hyperinsulinemia is the primary cause of fasting hyperglycemia; after a meal, impaired suppression of hepatic glucose ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-131-4-199908170-00008

    authors: DeFronzo RA

    更新日期:1999-08-17 00:00:00

  • Clinical ecology. American College of Physicians.

    abstract::Clinical ecologists propose the existence of a unique illness in which multiple environmental chemicals, foods, drugs, and endogenous C. albicans have a toxic effect on the immune system, thereby adversely affecting other bodily functions. The proposal uses some concepts that superficially resemble those that apply to...

    journal_title:Annals of internal medicine

    pub_type: 指南,杂志文章,实务指引,评审

    doi:

    authors:

    更新日期:1989-07-15 00:00:00

  • Narrative review: lack of evidence for recommended low-density lipoprotein treatment targets: a solvable problem.

    abstract::Recent national recommendations have proposed that physicians should titrate lipid therapy to achieve low-density lipoprotein (LDL) cholesterol levels less than 1.81 mmol/L (<70 mg/dL) for patients at very high cardiovascular risk and less than 2.59 mmol/L (<100 mg/dL) for patients at high cardiovascular risk. To exam...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-145-7-200610030-00010

    authors: Hayward RA,Hofer TP,Vijan S

    更新日期:2006-10-03 00:00:00

  • Management strategies for Helicobacter pylori-seropositive patients with dyspepsia: clinical and economic consequences.

    abstract:BACKGROUND:Noninvasive testing for Helicobacter pylori is widely available and has been considered as an initial management strategy for uninvestigated dyspepsia. However, data to guide clinicians in the management of patients with dyspepsia who are seropositive for H. pylori are lacking. OBJECTIVE:To examine the econ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-126-4-199702150-00004

    authors: Ofman JJ,Etchason J,Fullerton S,Kahn KL,Soll AH

    更新日期:1997-02-15 00:00:00

  • Pathologic findings in guinea pigs inoculated intraperitoneally with the Legionnaires' disease bacterium.

    abstract::Tissues from guinea pigs inoculated intraperitoneally with the Legionnaires' disease (LD) bacterium were studied with light, immunofluorescent, and electron microscopy. The principal gross lesion was diffuse peritonitis of varying severity. Microscopically, the peritonitis of covered by a mixed inflammatory infiltrate...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-90-4-671

    authors: Chandler FW,McDade JE,Hicklin MD,Blackmon JA,Thomason BM,Ewing EP Jr

    更新日期:1979-04-01 00:00:00

  • Minocycline in rheumatoid arthritis. A 48-week, double-blind, placebo-controlled trial. MIRA Trial Group.

    abstract:OBJECTIVE:To assess the safety and efficacy of minocycline in the treatment of rheumatoid arthritis. DESIGN:A double-blind, randomized, multicenter, 48-week trial of oral minocycline (200 mg/d) or placebo. SETTING:6 clinical centers in the United States. PATIENTS:219 adults with active rheumatoid arthritis who had p...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.7326/0003-4819-122-2-199501150-00001

    authors: Tilley BC,Alarcón GS,Heyse SP,Trentham DE,Neuner R,Kaplan DA,Clegg DO,Leisen JC,Buckley L,Cooper SM,Duncan H,Pillemer SR,Tuttleman M,Fowler SE

    更新日期:1995-01-15 00:00:00

  • Screening for peripheral artery disease and cardiovascular disease risk assessment with the ankle-brachial index in adults: U.S. Preventive Services Task Force recommendation statement.

    abstract:DESCRIPTION:Update of the 2005 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for peripheral artery disease (PAD). METHODS:The USPSTF reviewed the evidence on the use of resting ankle-brachial index (ABI) as a screening test for PAD or as a risk predictor for cardiovascular disease (CVD). The...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,实务指引

    doi:10.7326/0003-4819-159-5-201309030-00008

    authors: Moyer VA,U.S. Preventive Services Task Force.

    更新日期:2013-09-03 00:00:00

  • Removal of toxic levels of N-acetylprocainamide with continuous arteriovenous hemofiltration or continuous arteriovenous hemodiafiltration.

    abstract::Two patients with renal failure developed N-acetylprocainamide toxicity while receiving procainamide. Treatment consisted of continuous arteriovenous hemofiltration in one and hemodialysis followed by continuous arteriovenous hemodiafiltration in the other. The efficacy of these treatments was compared with the effica...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-106-4-550

    authors: Domoto DT,Brown WW,Bruggensmith P

    更新日期:1987-04-01 00:00:00

  • Acute renal infection in women: treatment with trimethoprim-sulfamethoxazole or ampicillin for two or six weeks. A randomized trial.

    abstract::We compared the efficacy of orally administered ampicillin, 2 g/d, with that of trimethoprim-sulfamethoxazole, 320 mg/d-1600 mg/d, given for 2 or 6 weeks for outpatient management of acute uncomplicated renal infection in women. Of 98 women participating in the trial, 60 had renal infections with susceptible strains, ...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.7326/0003-4819-106-3-341

    authors: Stamm WE,McKevitt M,Counts GW

    更新日期:1987-03-01 00:00:00

  • National Study of Internal Medicine Manpower. XVIII: Subspecialty fellowships with a special look at hematology and oncology, 1988-1989.

    abstract:OBJECTIVE:To determine the number and distribution of internists in subspecialty training and compare with data collected since 1976; to determine the distribution of activity of subspecialty fellows; and to focus on hematology and oncology. DESIGN:Repeated mail survey with telephone follow-up. PARTICIPANTS:All direc...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-114-1-36

    authors: Lyttle CS,Andersen RM,Neymarc K,Schmidt C,Kohrman CH,Levey GS

    更新日期:1991-01-01 00:00:00

  • Theophylline reassessed.

    abstract::Advances have recently been made in understanding the pharmacokinetics of theophylline. To correlate the new knowledge of theophylline pharmacokinetics with the drug's current status in therapy, we have critically reviewed the relevant investigations of the last 5 years. We consider data on its presumed mechanisms of ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-101-1-63

    authors: Bukowskyj M,Nakatsu K,Munt PW

    更新日期:1984-07-01 00:00:00

  • Systematic review: impact of health information technology on quality, efficiency, and costs of medical care.

    abstract:BACKGROUND:Experts consider health information technology key to improving efficiency and quality of health care. PURPOSE:To systematically review evidence on the effect of health information technology on quality, efficiency, and costs of health care. DATA SOURCES:The authors systematically searched the English-lang...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-144-10-200605160-00125

    authors: Chaudhry B,Wang J,Wu S,Maglione M,Mojica W,Roth E,Morton SC,Shekelle PG

    更新日期:2006-05-16 00:00:00

  • Documentation and evaluation of cognitive impairment in elderly primary care patients.

    abstract:OBJECTIVE:To describe the prevalence of cognitive impairment among elderly primary care patients and to compare diagnostic evaluations and use of health services among patients with and those without cognitive impairment. DESIGN:Prospective cohort study. SETTING:Academic primary care group practice. PATIENTS:3954 pa...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-122-6-199503150-00004

    authors: Callahan CM,Hendrie HC,Tierney WM

    更新日期:1995-03-15 00:00:00

  • Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society.

    abstract:DESCRIPTION:This guideline is an official statement of the American College of Physicians (ACP), American College of Chest Physicians (ACCP), American Thoracic Society (ATS), and European Respiratory Society (ERS). It represents an update of the 2007 ACP clinical practice guideline on diagnosis and management of stable...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,实务指引

    doi:10.7326/0003-4819-155-3-201108020-00008

    authors: Qaseem A,Wilt TJ,Weinberger SE,Hanania NA,Criner G,van der Molen T,Marciniuk DD,Denberg T,Schünemann H,Wedzicha W,MacDonald R,Shekelle P,American College of Physicians.,American College of Chest Physicians.,American Thoracic

    更新日期:2011-08-02 00:00:00

  • Brief Cognitive Tests for Distinguishing Clinical Alzheimer-Type Dementia From Mild Cognitive Impairment or Normal Cognition in Older Adults With Suspected Cognitive Impairment.

    abstract:BACKGROUND:The accuracy and harms of brief cognitive tests for identifying clinical Alzheimer-type dementia (CATD) are uncertain. PURPOSE:To summarize evidence on accuracy and harms of brief cognitive tests for CATD in older adults with suspected cognitive impairment. DATA SOURCES:Electronic bibliographic databases (...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/M19-3889

    authors: Hemmy LS,Linskens EJ,Silverman PC,Miller MA,Talley KMC,Taylor BC,Ouellette JM,Greer NL,Wilt TJ,Butler M,Fink HA

    更新日期:2020-05-19 00:00:00

  • Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in atrial fibrillation.

    abstract:BACKGROUND:Warfarin reduces the risk for ischemic stroke in patients with atrial fibrillation (AF) but increases the risk for hemorrhage. Dabigatran is a fixed-dose, oral direct thrombin inhibitor with similar or reduced rates of ischemic stroke and intracranial hemorrhage in patients with AF compared with those of war...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-154-1-201101040-00289

    authors: Freeman JV,Zhu RP,Owens DK,Garber AM,Hutton DW,Go AS,Wang PJ,Turakhia MP

    更新日期:2011-01-04 00:00:00

  • Low-dose chest CT had 95% sensitivity and 91% specificity for diagnosing COVID-19 in patients with clinical symptoms.

    abstract:SOURCE CITATION:Schulze-Hagen M, Hübel C, Meier-Schroers M, et al. Low-dose chest CT for the diagnosis of COVID-19. Dtsch Arztebl Int. 2020;117:389-95. 32762834. ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,多中心研究

    doi:10.7326/ACPJ202012150-068

    authors: Long B

    更新日期:2020-12-15 00:00:00

  • Tipping the balance of benefits and harms to favor screening mammography starting at age 40 years: a comparative modeling study of risk.

    abstract:BACKGROUND:Timing of initiation of screening for breast cancer is controversial in the United States. OBJECTIVE:To determine the threshold relative risk (RR) at which the harm-benefit ratio of screening women aged 40 to 49 years equals that of biennial screening for women aged 50 to 74 years. DESIGN:Comparative model...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-156-9-201205010-00002

    authors: van Ravesteyn NT,Miglioretti DL,Stout NK,Lee SJ,Schechter CB,Buist DS,Huang H,Heijnsdijk EA,Trentham-Dietz A,Alagoz O,Near AM,Kerlikowske K,Nelson HD,Mandelblatt JS,de Koning HJ

    更新日期:2012-05-01 00:00:00

  • Effect of early cerebral magnetic resonance imaging on clinical decisions in infective endocarditis: a prospective study.

    abstract:BACKGROUND:Neurologic complications of endocarditis can influence diagnosis, therapeutic plans, and prognosis. OBJECTIVE:To describe how early cerebral magnetic resonance imaging (MRI) affects the diagnosis and management of endocarditis in hospitalized adults. DESIGN:Single-center prospective study between June 2005...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-152-8-201004200-00006

    authors: Duval X,Iung B,Klein I,Brochet E,Thabut G,Arnoult F,Lepage L,Laissy JP,Wolff M,Leport C,IMAGE (Resonance Magnetic Imaging at the Acute Phase of Endocarditis) Study Group.

    更新日期:2010-04-20 00:00:00

  • Mutations in mouse myeloma cells: implications for human multiple myeloma and the production of immunoglobulins.

    abstract::Multiple myeloma raises a number of puzzling questions about the production of immunoglobulins and the malignant transformation of lymphoid cells. Some of these questions can be approached by studying mouse plasmacytomas and by genetic and biochemical studies of mouse myeloma cells in culture. The synthesis, assembly,...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-85-1-110

    authors: Weitzman S,Margulies DH,Scharff MD

    更新日期:1976-07-01 00:00:00

  • Effects of nurse-managed protocols in the outpatient management of adults with chronic conditions: a systematic review and meta-analysis.

    abstract:BACKGROUND:Changes in federal health policy are providing more access to medical care for persons with chronic disease. Providing quality care may require a team approach, which the American College of Physicians calls the "medical home." One new model may involve nurse-managed protocols. PURPOSE:To determine whether ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,meta分析

    doi:10.7326/M13-2567

    authors: Shaw RJ,McDuffie JR,Hendrix CC,Edie A,Lindsey-Davis L,Nagi A,Kosinski AS,Williams JW Jr

    更新日期:2014-07-15 00:00:00

  • Clinical management of intractable constipation.

    abstract:PURPOSE:To review current management of intractable constipation. DATA SOURCES:Original articles and reviews published in the English-language literature between 1965 and 1993 identified by MEDLINE search. Verbal feedback from attendees after presentation of the document as a clinical symposium at the 14th Internation...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-121-7-199410010-00008

    authors: Camilleri M,Thompson WG,Fleshman JW,Pemberton JH

    更新日期:1994-10-01 00:00:00

  • The association of HIV susceptibility testing with survival among HIV-infected patients receiving antiretroviral therapy: a cohort study.

    abstract:BACKGROUND:HIV-1 genotypic and phenotypic susceptibility testing (GPT) optimizes antiretroviral selection, but its effect on survival is unknown. OBJECTIVE:To evaluate the association between GPT and survival. DESIGN:Cohort study. SETTING:10 U.S. HIV clinics. PATIENTS:2699 HIV-infected patients eligible for GPT (pl...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,多中心研究

    doi:10.7326/0003-4819-151-2-200907210-00003

    authors: Palella FJ Jr,Armon C,Buchacz K,Cole SR,Chmiel JS,Novak RM,Wood K,Moorman AC,Brooks JT,HOPS (HIV Outpatient Study) Investigators.

    更新日期:2009-07-21 00:00:00

  • Cost-effectiveness of transesophageal echocardiography to determine the duration of therapy for intravascular catheter-associated Staphylococcus aureus bacteremia.

    abstract:BACKGROUND:The appropriate duration of therapy for catheter-associated Staphylococcus aureus bacteremia is controversial. Conventional practice dictates that all patients receive prolonged courses of intravenous antibiotics. Some clinicians recommend abbreviated therapeutic courses, but an alternate approach involves p...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-130-10-199905180-00004

    authors: Rosen AB,Fowler VG Jr,Corey GR,Downs SM,Biddle AK,Li J,Jollis JG

    更新日期:1999-05-18 00:00:00

  • Prediction of pulmonary embolism in the emergency department: the revised Geneva score.

    abstract:BACKGROUND:Diagnosis of pulmonary embolism requires clinical probability assessment. Implicit assessment is accurate but is not standardized, and current prediction rules have shortcomings. OBJECTIVE:To construct a simple score based entirely on clinical variables and independent from physicians' implicit judgment. D...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-144-3-200602070-00004

    authors: Le Gal G,Righini M,Roy PM,Sanchez O,Aujesky D,Bounameaux H,Perrier A

    更新日期:2006-02-07 00:00:00

  • Pituitary stones.

    abstract::Two cases of patients having calcification within the sella turcica (pituitary stones) have been studied and followed up, one patient for 18 years. A detailed analysis of the radiographic findings and endocrinologic profiles of these two patients is presented. The rarity of bona fide pituitary stones and their benign ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-83-1-66

    authors: Di Chiro G,Saldino R,McGuffin WL Jr,Sachson RA,Gorden P,Bartter FC

    更新日期:1975-07-01 00:00:00

  • A practice guideline revisited: screening for hypertension.

    abstract::In 1993, the Clinical Efficacy Assessment Subcommittee began evaluation of new topics and reevaluation of previous guidelines on common screening tests, which were published in Annals of Internal Medicine between 1988 and 1990 and republished as a collection in 1991 (Eddy DM, ed. Common Screening Tests. Philadelphia: ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-122-12-199506150-00008

    authors: Littenberg B

    更新日期:1995-06-15 00:00:00

  • Aspirin hepatotoxicity and disseminated intravascular coagulation.

    abstract::A 17-year-old girl with a clinical diagnosis of adult-type juvenile rheumatoid arthritis developed a severe hepatotoxic reaction to 3.6 g of aspirin per day. This was associated with a microangiopathic anemia and transient congestive cardiac failure. She responded well to steroids, and when all laboratory test finding...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-86-2-183

    authors: Sbarbaro JA,Bennett RM

    更新日期:1977-02-01 00:00:00