Pathologic findings in guinea pigs inoculated intraperitoneally with the Legionnaires' disease bacterium.

abstract：:Hepatitis is a significant complication of the treatment of hemophilia A with factor VIII concentrates. Chronic liver disease in these patients is infrequently documented in the literature. The results of percutaneous liver biopsy, under the coverage of glycine-precipitated factor VIII, in six patients with hemophilia...

journal_title：Annals of internal medicine

authors： Lesesne HR,Morgan JE,Blatt PM,Webster WP,Roberts HR

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:Mesenchymal stem cells can differentiate into endothelial cells and participate in angiogenesis in adults. In experimental models of acute myocardial infarction, mesenchymal stem cells led to the recovery of cardiac function through the formation of a new vascular network. OBJECTIVE:To describe treatment wi...

journal_title：Annals of internal medicine

authors： Guiducci S,Porta F,Saccardi R,Guidi S,Ibba-Manneschi L,Manetti M,Mazzanti B,Dal Pozzo S,Milia AF,Bellando-Randone S,Miniati I,Fiori G,Fontana R,Amanzi L,Braschi F,Bosi A,Matucci-Cerinic M

更新日期：2010-11-16 00:00:00

abstract：BACKGROUND:Although HIV infection is more prevalent in people younger than age 45 years, a substantial number of infections occur in older persons. Recent guidelines recommend HIV screening in patients age 13 to 64 years. The cost-effectiveness of HIV screening in patients age 55 to 75 years is uncertain. OBJECTIVE:To...

journal_title：Annals of internal medicine

authors： Sanders GD,Bayoumi AM,Holodniy M,Owens DK

更新日期：2008-06-17 00:00:00

abstract：:We evaluated 10 patients with hidradenitis suppurative or acne conglobata who developed arthritis. In contrast to patients with acne fulminans and arthritis, all our subjects were adults over 22 years of age; nine were black; and four were women. Nine patients had episodic inflammatory oligoarthritis affecting mainly ...

journal_title：Annals of internal medicine

authors： Rosner IA,Richter DE,Huettner TL,Kuffner GH,Wisnieski JJ,Burg CG

更新日期：1982-10-01 00:00:00

abstract：:A 53-year-old librarian had recurrent palpable purpura on her ankles and legs that was found to be caused by the fumes released from heat-activated photocopy paper at her place of employment. Behenic acid was identified as the responsible chemical component through a series of challenge studies that simulated her work...

journal_title：Annals of internal medicine

authors： Tencati JR,Novey HS

更新日期：1983-03-01 00:00:00

abstract：Background:Triplex vaccine was developed to enhance cytomegalovirus (CMV)-specific T cells and prevent CMV reactivation early after hematopoietic stem cell transplant (HCT). Objective:To determine the safety and efficacy of Triplex. Design:First-in-patient, phase 2 trial. (ClinicalTrials.gov: NCT02506933). Setting:3...

journal_title：Annals of internal medicine

authors： Aldoss I,La Rosa C,Baden LR,Longmate J,Ariza-Heredia EJ,Rida WN,Lingaraju CR,Zhou Q,Martinez J,Kaltcheva T,Dagis A,Hardwick N,Issa NC,Farol L,Nademanee A,Al Malki MM,Forman S,Nakamura R,Diamond DJ,TRIPLEX VACCINE St

更新日期：2020-03-03 00:00:00

abstract：Background:Cardiovascular implantable electronic devices (CIEDs) are associated with procedure-related complications, yet little is known about variation in complication rates among institutions that may suggest disparities in care quality. Objective:To assess institutional variation in risk-standardized complication ...

journal_title：Annals of internal medicine

authors： Ranasinghe I,Labrosciano C,Horton D,Ganesan A,Curtis JP,Krumholz HM,McGavigan A,Hossain S,Air T,Hariharaputhiran S

更新日期：2019-09-03 00:00:00

abstract：OBJECTIVE:To estimate relative risk of mortality and median life expectancy for patients with classic hemophilia by a life-table analysis, taking into account deaths that may have occurred in infancy or childhood before the onset of symptoms. DESIGN:Retrospective chart review of clinical series. SETTING:Referral-base...

journal_title：Annals of internal medicine

authors： Jones PK,Ratnoff OD

更新日期：1991-04-15 00:00:00

abstract：SOURCE CITATION:Cao B, Wang Y, Wen D, et al. A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19. N Engl J Med. 2020;382:1787-99. 32187464. ...

journal_title：Annals of internal medicine

authors： Yang P,Tekwani S,Martin GS

更新日期：2020-06-16 00:00:00

abstract：:Since 1969, medications have been provided to patients at the Johns Hopkins Hospital using a computer system that controls the entire medication process from entry of physician's order to hourly drug distribution. Special envelopes containing patient and dosage information are computer generated for each dose to be ad...

journal_title：Annals of internal medicine

authors： Simborg DW,Derewicz HJ

更新日期：1975-09-01 00:00:00

abstract：:Clinical and epidemiologic characteristics of disease associated with a newly described nonhalophilic Vibrio species, Vibrio mimicus, were identified by studying isolates from 21 patients referred to the Centers for Disease Control between 1977 and 1981. Two isolates were from the ears of patients with otitis who had ...

journal_title：Annals of internal medicine

authors： Shandera WX,Johnston JM,Davis BR,Blake PA

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:Two recent double-blind, randomized, controlled trials (RCTs) showed that oral steroids and nonsteroidal anti-inflammatory drugs have similar analgesic effectiveness for management of gout, but the trials had small sample sizes and other methodological limitations. OBJECTIVE:To compare the effectiveness and...

journal_title：Annals of internal medicine

authors： Rainer TH,Cheng CH,Janssens HJ,Man CY,Tam LS,Choi YF,Yau WH,Lee KH,Graham CA

更新日期：2016-04-05 00:00:00

abstract：:Recent data indicate that the lymphadenopathy-associated virus (LAV) is morphologically similar to animal lentiviruses, such as equine infectious anemia and visna viruses. This finding, together with the cross-reactivity of the core proteins of LAV with those of the equine infectious anemia virus and a similarity in g...

journal_title：Annals of internal medicine

authors： Montagnier L

更新日期：1985-11-01 00:00:00

abstract：:To increase the utility of administrative databases, it has been recommended that they include disease-specific, patient-centered outcome measures. This paper reviews practical and theoretical considerations and the critical evidence to support this recommendation. The strengths and weaknesses of the recommended appro...

journal_title：Annals of internal medicine

authors： Liang MH,Shadick N

更新日期：1997-10-15 00:00:00

abstract：BACKGROUND:Nurse care management programs for patients with chronic illness have been shown to be safe and effective. OBJECTIVE:To determine whether a telephone-mediated nurse care management program for heart failure reduced the rate of rehospitalization for heart failure and for all causes over a 1-year period. DES...

journal_title：Annals of internal medicine

authors： DeBusk RF,Miller NH,Parker KM,Bandura A,Kraemer HC,Cher DJ,West JA,Fowler MB,Greenwald G

更新日期：2004-10-19 00:00:00

abstract：BACKGROUND:Without population-based evidence, some clinicians recommend short-term suspension of hormone therapy to improve the performance of mammography. Hormone therapy increases breast density, and abnormal screening mammograms are more common among women with denser breasts and among women using hormone therapy. ...

journal_title：Annals of internal medicine

authors： Buist DS,Anderson ML,Reed SD,Aiello Bowles EJ,Fitzgibbons ED,Gandara JC,Seger D,Newton KM

更新日期：2009-06-02 00:00:00

abstract：OBJECTIVE:To describe the effects of human immunodeficiency virus (HIV) infection on the serologic manifestations and response to treatment of syphilis in intravenous drug users. DESIGN:Cohort study of intravenous drug users. SETTING:Medical clinic in a hospital-based methadone maintenance treatment program in New Yo...

journal_title：Annals of internal medicine

authors： Gourevitch MN,Selwyn PA,Davenny K,Buono D,Schoenbaum EE,Klein RS,Friedland GH

更新日期：1993-03-01 00:00:00

abstract：PURPOSE:To review the electropharmacology, clinical applications, side effects, and hemodynamic profile of intravenous amiodarone. DATA SOURCES:The MEDLINE database was searched for English-language material, including reports of clinical trials and in vivo studies, review articles, and abstracts presented at national...

journal_title：Annals of internal medicine

authors： Desai AD,Chun S,Sung RJ

更新日期：1997-08-15 00:00:00

abstract：Background:Zika virus has spread rapidly in the Americas and has been imported into many nonendemic countries by travelers. Objective:To describe clinical manifestations and epidemiology of Zika virus disease in travelers exposed in the Americas. Design:Descriptive, using GeoSentinel records. Setting:63 travel and t...

journal_title：Annals of internal medicine

authors： Hamer DH,Barbre KA,Chen LH,Grobusch MP,Schlagenhauf P,Goorhuis A,van Genderen PJ,Molina I,Asgeirsson H,Kozarsky PE,Caumes E,Hagmann SH,Mockenhaupt FP,Eperon G,Barnett ED,Bottieau E,Boggild AK,Gautret P,Hynes NA,Kuhn

更新日期：2017-01-17 00:00:00

abstract：BACKGROUND:Primary prevention of Alzheimer disease and other types of dementia (all-cause dementia) is an important public health goal. Evidence to date is insufficient to recommend any lifestyle change to prevent or delay the onset of dementia. OBJECTIVE:To assess the association between objectively measured midlife ...

journal_title：Annals of internal medicine

authors： Defina LF,Willis BL,Radford NB,Gao A,Leonard D,Haskell WL,Weiner MF,Berry JD

更新日期：2013-02-05 00:00:00

abstract：BACKGROUND:Testing has been advocated for all persons with newly diagnosed colorectal cancer to identify families with the Lynch syndrome, an autosomal dominant cancer-predisposition syndrome that is a paradigm for personalized medicine. OBJECTIVE:To estimate the effectiveness and cost-effectiveness of strategies to i...

journal_title：Annals of internal medicine

authors： Ladabaum U,Wang G,Terdiman J,Blanco A,Kuppermann M,Boland CR,Ford J,Elkin E,Phillips KA

更新日期：2011-07-19 00:00:00

abstract：STUDY OBJECTIVE:To assess respiratory muscle fatigue in acute respiratory failure in patients with chronic obstructive pulmonary disease and evaluate its influence on weaning patients from mechanical ventilation. DESIGN AND PATIENTS:We studied the time course of tracheal occlusion pressure (P0.1) and high-to-low ratio...

journal_title：Annals of internal medicine

authors： Murciano D,Boczkowski J,Lecocguic Y,Emili JM,Pariente R,Aubier M

更新日期：1988-06-01 00:00:00

abstract：:Although disease caused by Arizona hinshawii is known to resemble the spectrum of clinical syndromes seen with Salmonella infections, little is known of their sensitivity to antimicrobials. We present three cases that are illustrative of Arizona sepsis, localized infection, or both; review the literature; and report s...

journal_title：Annals of internal medicine

authors： Johnson RH,Lutwick LI,Huntley GA,Vosti KL

更新日期：1976-11-01 00:00:00

abstract：:Sera of 24 patients with an unexplained pneumonia were tested for the presence of antibodies against the Legionnaires' disease bacterium. Fifteen patients had positive serology. The series comprised 12 male and three female patients ranging in age from 17 to 66 years (mean, 51.1 years). All of the patients had a high ...

journal_title：Annals of internal medicine

authors： Meenhorst PL,van der Meer JW,Borst J

更新日期：1979-04-01 00:00:00

abstract：:Recent research on human macrophage activation has reemphasized the critical role of the lymphokine-secreting T cell in converting quiescent macrophages to efficient microbicidal phagocytes. Interferon-gamma, a key lymphokine secreted by antigen-triggered T4+ helper cells, is capable of inducing the macrophage to act ...

journal_title：Annals of internal medicine

authors： Murray HW

更新日期：1988-04-01 00:00:00

abstract：:For the diagnosis of M7, the bone marrow aspirate shows a leukemic cell infiltrate that comprises 30% or more of all cells. These cells are identified as being of megakaryocyte lineage by the platelet peroxidase reaction on electron microscopy or by tests with monoclonal or polyclonal platelet-specific antibodies. Mye...

journal_title：Annals of internal medicine

authors： Bennett JM,Catovsky D,Daniel MT,Flandrin G,Galton DA,Gralnick HR,Sultan C

更新日期：1985-09-01 00:00:00

abstract：STUDY OBJECTIVE:To assess the effect of weight-bearing exercise training and subsequent detraining on lumbar bone mineral content in postmenopausal women. DESIGN:Non-randomized, controlled, short-term (9 months) trial and long-term (22 months) exercise training and detraining (13 months). SETTING:Section of applied p...

journal_title：Annals of internal medicine

authors： Dalsky GP,Stocke KS,Ehsani AA,Slatopolsky E,Lee WC,Birge SJ Jr

更新日期：1988-06-01 00:00:00

abstract：:The systemic capillary leak syndrome (SCLS) is a rare disease of reversible plasma extravasation and vascular collapse accompanied by hemoconcentration and hypoalbuminemia. Its cause is unknown, although it is believed to be a manifestation of transient endothelial dysfunction due to endothelial contraction, apoptosis...

journal_title：Annals of internal medicine

authors： Druey KM,Greipp PR

更新日期：2010-07-20 00:00:00

abstract：BACKGROUND:The optimal strategy to prevent recurrent presumed paradoxical emboli in patients with patent foramen ovale is unknown. PURPOSE:To synthesize the current knowledge about and qualitatively assess the relative benefits of transcatheter closure versus medical therapy for patent foramen ovale. DATA SOURCES:Eng...

journal_title：Annals of internal medicine

authors： Khairy P,O'Donnell CP,Landzberg MJ

更新日期：2003-11-04 00:00:00

abstract：STUDY OBJECTIVE:To determine if the combination of ganciclovir and intravenous cytomegalovirus immunoglobulin is effective in patients with cytomegalovirus pneumonia after bone marrow transplant. DESIGN:Consecutive entry trial with treatment for a minimum of 14 days. PATIENTS:Consecutive sample of 25 patients with bo...

journal_title：Annals of internal medicine

authors： Reed EC,Bowden RA,Dandliker PS,Lilleby KE,Meyers JD

更新日期：1988-11-15 00:00:00