Effects of nurse-managed protocols in the outpatient management of adults with chronic conditions: a systematic review and meta-analysis.

Abstract:

BACKGROUND:Changes in federal health policy are providing more access to medical care for persons with chronic disease. Providing quality care may require a team approach, which the American College of Physicians calls the "medical home." One new model may involve nurse-managed protocols. PURPOSE:To determine whether nurse-managed protocols are effective for outpatient management of adults with diabetes, hypertension, and hyperlipidemia. DATA SOURCES:MEDLINE, Cochrane Central Register of Controlled Trials, EMBASE, and CINAHL from January 1980 through January 2014. STUDY SELECTION:Two reviewers used eligibility criteria to assess all titles, abstracts, and full texts and resolved disagreements by discussion or by consulting a third reviewer. DATA EXTRACTION:One reviewer did data abstractions and quality assessments, which were confirmed by a second reviewer. DATA SYNTHESIS:From 2954 studies, 18 were included. All studies used a registered nurse or equivalent who titrated medications by following a protocol. In a meta-analysis, hemoglobin A1c level decreased by 0.4% (95% CI, 0.1% to 0.7%) (n = 8); systolic and diastolic blood pressure decreased by 3.68 mm Hg (CI, 1.05 to 6.31 mm Hg) and 1.56 mm Hg (CI, 0.36 to 2.76 mm Hg), respectively (n = 12); total cholesterol level decreased by 0.24 mmol/L (9.37 mg/dL) (CI, 0.54-mmol/L decrease to 0.05-mmol/L increase [20.77-mg/dL decrease to 2.02-mg/dL increase]) (n = 9); and low-density-lipoprotein cholesterol level decreased by 0.31 mmol/L (12.07 mg/dL) (CI, 0.73-mmol/L decrease to 0.11-mmol/L increase [28.27-mg/dL decrease to 4.13-mg/dL increase]) (n = 6). LIMITATION:Studies had limited descriptions of the interventions and protocols used. CONCLUSION:A team approach that uses nurse-managed protocols may have positive effects on the outpatient management of adults with chronic conditions, such as diabetes, hypertension, and hyperlipidemia. PRIMARY FUNDING SOURCE:U.S. Department of Veterans Affairs.

journal_name

Ann Intern Med

authors

Shaw RJ,McDuffie JR,Hendrix CC,Edie A,Lindsey-Davis L,Nagi A,Kosinski AS,Williams JW Jr

doi

10.7326/M13-2567

subject

Has Abstract

pub_date

2014-07-15 00:00:00

pages

113-21

issue

2

eissn

0003-4819

issn

1539-3704

pii

1887028

journal_volume

161

pub_type

杂志文章,meta分析
  • Cost-effectiveness of HIV screening in patients older than 55 years of age.

    abstract:BACKGROUND:Although HIV infection is more prevalent in people younger than age 45 years, a substantial number of infections occur in older persons. Recent guidelines recommend HIV screening in patients age 13 to 64 years. The cost-effectiveness of HIV screening in patients age 55 to 75 years is uncertain. OBJECTIVE:To...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-148-12-200806170-00002

    authors: Sanders GD,Bayoumi AM,Holodniy M,Owens DK

    更新日期:2008-06-17 00:00:00

  • Wegener granulomatosis: an analysis of 158 patients.

    abstract:OBJECTIVE:To prospectively study the clinical features, pathophysiology, treatment and prognosis of Wegener granulomatosis. DESIGN:Of the 180 patients with Wegener granulomatosis referred to the National Institute of Allergy and Infectious Diseases during the past 24 years, 158 have been followed for 6 months to 24 ye...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-116-6-488

    authors: Hoffman GS,Kerr GS,Leavitt RY,Hallahan CW,Lebovics RS,Travis WD,Rottem M,Fauci AS

    更新日期:1992-03-15 00:00:00

  • Antigenemia detected by radioimmunoassay in systemic aspergillosis.

    abstract::Because of difficulties in antemortem diagnosis of systemic aspergillosis, a radioimmunoassay to an Aspergillus fumigatus carbohydrate was developed and evaluated in patients with mycotic or bacterial infections. Antigenemia was detected in sera obtained antemortem from four of seven patients with systemic aspergillos...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-92-6-793

    authors: Weiner MH

    更新日期:1980-06-01 00:00:00

  • Type III hyperlipoproteinemia: diagnosis in whole plasma by apolipoprotein-E immunoassay.

    abstract::Because the cholesterol-rich very low density (VLD) lipoproteins of subjects with type III hyperlipoproteinemia are distinctively enriched in apolipoprotein E, a radial immunodiffusion assay for apolipoprotein E in whole plasma was developed. Its diagnostic usefulness was tested in randomly selected (n = 174) and hype...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-87-5-509

    authors: Kushwaha RS,Hazzard WR,Wahl PW,Hoover JJ

    更新日期:1977-11-01 00:00:00

  • Toward a 21st-century health care system: recommendations for health care reform.

    abstract::The coverage, cost, and quality problems of the U.S. health care system are evident. Sustainable health care reform must go beyond financing expanded access to care to substantially changing the organization and delivery of care. The FRESH-Thinking Project (www.fresh-thinking.org) held a series of workshops during whi...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-150-7-200904070-00115

    authors: Arrow K,Auerbach A,Bertko J,Brownlee S,Casalino LP,Cooper J,Crosson FJ,Enthoven A,Falcone E,Feldman RC,Fuchs VR,Garber AM,Gold MR,Goldman D,Hadfield GK,Hall MA,Horwitz RI,Hooven M,Jacobson PD,Jost TS,Kotlikoff LJ

    更新日期:2009-04-07 00:00:00

  • Discordant thymectomy in identical twins concordant for myasthenia gravis.

    abstract:BACKGROUND:Thymectomy is standard therapy fornonthymomatousmyasthenia gravis despite the absence of randomized clinical trials (1). Myasthenia gravis is uncommonly reported in monozygous twins; disease concordance occurs in approximately one third of such identical twin pairs; and treatment for myasthenia gravis, when ...

    journal_title:Annals of internal medicine

    pub_type: 信件

    doi:10.7326/0003-4819-155-7-201110040-00016

    authors: Riggs KR,Gutmann L,Riggs JE

    更新日期:2011-10-04 00:00:00

  • Physical examination for exclusion of hemodynamically important right ventricular infarction.

    abstract::Fifty-three consecutive patients with inferior myocardial infarction were evaluated prospectively, by physical examination and right heart catheterization within 36 hours of the onset of symptoms, to determine whether physical findings can separate such patients into those with and without associated right ventricular...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-99-5-608

    authors: Dell'Italia LJ,Starling MR,O'Rourke RA

    更新日期:1983-11-01 00:00:00

  • National Institutes of Health Pathways to Prevention Workshop: Achieving Health Equity in Preventive Services.

    abstract::Expert groups, including the U.S. Preventive Services Task Force (USPSTF), recommend a range of clinical preventive services for persons at average risk for disease. Use of these services often is substantially lower among racial and ethnic minority groups, rural residents, and persons of lower socioeconomic status. O...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/M19-3171

    authors: Carey TS,Bekemeier B,Campos-Outcalt D,Koch-Weser S,Millon-Underwood S,Teutsch S

    更新日期:2020-02-18 00:00:00

  • Calibration of the Pooled Cohort Equations for Atherosclerotic Cardiovascular Disease: An Update.

    abstract::The latest guidelines from the American College of Cardiology and American Heart Association, released in fall 2013, provide a long-anticipated update to the recommendations of the Third Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/M16-1739

    authors: Cook NR,Ridker PM

    更新日期:2016-12-06 00:00:00

  • Behavioral Programs for Type 1 Diabetes Mellitus: A Systematic Review and Meta-analysis.

    abstract:BACKGROUND:Whether behavioral approaches for self-management programs benefit individuals with type 1 diabetes mellitus is unclear. PURPOSE:To determine the effects of behavioral programs for patients with type 1 diabetes on behavioral, clinical, and health outcomes and to investigate factors that might moderate effec...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.7326/M15-1399

    authors: Pillay J,Armstrong MJ,Butalia S,Donovan LE,Sigal RJ,Chordiya P,Dhakal S,Vandermeer B,Hartling L,Nuspl M,Featherstone R,Dryden DM

    更新日期:2015-12-01 00:00:00

  • Evidence for success of behavior modification in weight loss and control.

    abstract::Behavior modification applied to the treatment of obesity has evolved from the environmental control of eating behavior to a broader approach characterized by systematic manipulation of all factors associated with eating and exercise patterns. This approach has shown success in helping obese persons lose modest amount...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-119-7_part_2-199310011-00014

    authors: Foreyt JP,Goodrick GK

    更新日期:1993-10-01 00:00:00

  • Hypomagnesemia and impaired parathyroid hormone secretion in chronic renal disease.

    abstract::Severe hypocalcemia secondary to magnesium depletion has been described in numerous patients with gastrointestinal disorders. The development of profound hypomagnesemia in chronic renal disease is a rare finding. We studied three patients with advanced renal failure and magnesium depletion. Severe hypocalcemia also wa...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-88-2-206

    authors: Mennes P,Rosenbaum R,Martin K,Slatopolsky E

    更新日期:1978-02-01 00:00:00

  • Feasibility and utility of adding disease-specific outcome measures to administrative databases to improve disease management.

    abstract::To increase the utility of administrative databases, it has been recommended that they include disease-specific, patient-centered outcome measures. This paper reviews practical and theoretical considerations and the critical evidence to support this recommendation. The strengths and weaknesses of the recommended appro...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-127-8_part_2-199710151-00060

    authors: Liang MH,Shadick N

    更新日期:1997-10-15 00:00:00

  • Treatment of intractable lupus nephritis with total lymphoid irradiation.

    abstract::Ten patients with lupus nephritis and marked proteinuria (3.9 g or more/d) that did not respond adequately to treatment with prednisone alone or prednisone in combination with azathioprine were treated with total lymphoid irradiation in an uncontrolled feasibility study. Within 6 weeks after the start of total lymphoi...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-102-4-450

    authors: Strober S,Field E,Hoppe RT,Kotzin BL,Shemesh O,Engleman E,Ross JC,Myers BD

    更新日期:1985-04-01 00:00:00

  • Using Public Cost Information During Low Back Pain Visits: A Qualitative Study.

    abstract:Background:Patients desire information about health care costs because they are increasingly responsible for these costs. Public Web sites that offer cost information could inform provider-patient discussions of costs at the point of care. Objective:To evaluate tools to facilitate the use of publicly available cost in...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,多中心研究

    doi:10.7326/M18-2223

    authors: Fox KS,Gray CE,Williamson ME,MacKenzie JA

    更新日期:2019-05-07 00:00:00

  • Building measurement and data collection into medical practice.

    abstract::Clinicians can use data to improve daily clinical practice. This paper offers eight principles for using data to support improvement in busy clinical settings: 1) seek usefulness, not perfection, in the measurement; 2) use a balanced set of process, outcome, and cost measures; 3) keep measurement simple (think big, bu...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-128-6-199803150-00007

    authors: Nelson EC,Splaine ME,Batalden PB,Plume SK

    更新日期:1998-03-15 00:00:00

  • Clinically silent atrial septal defects with evidence for cerebral embolization.

    abstract::The cause of stroke in young patients frequently cannot be established. Eleven consecutive patients, age 50 and younger, had clinical evidence of cerebral embolization. Results of physical, radiographic, electrocardiographic, and two-dimensional echocardiographic examinations were normal in all patients. During normal...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-105-5-695

    authors: Harvey JR,Teague SM,Anderson JL,Voyles WF,Thadani U

    更新日期:1986-11-01 00:00:00

  • The effect of recombinant human granulocyte-macrophage colony-stimulating factor on neutropenia and related morbidity in chronic severe neutropenia.

    abstract:STUDY OBJECTIVE:To define the clinical and hematologic effects of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) on patients with chronic severe neutropenia. DESIGN:Open-label, phase II study of rhGM-CSF. SETTING:Inpatient hematology and surgery clinic at a university medical center. P...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-111-11-887

    authors: Ganser A,Ottmann OG,Erdmann H,Schulz G,Hoelzer D

    更新日期:1989-12-01 00:00:00

  • Fluconazole prophylaxis of fungal infections in patients with acute leukemia. Results of a randomized placebo-controlled, double-blind, multicenter trial.

    abstract:OBJECTIVE:To evaluate the efficacy and safety of fluconazole for prevention of fungal infections. DESIGN:A randomized, placebo-controlled, double-blind, multicenter trial. PATIENTS:Adults (257) undergoing chemotherapy for acute leukemia. INTERVENTION:Patients were randomly assigned to receive either fluconazole (400...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.7326/0003-4819-118-7-199304010-00003

    authors: Winston DJ,Chandrasekar PH,Lazarus HM,Goodman JL,Silber JL,Horowitz H,Shadduck RK,Rosenfeld CS,Ho WG,Islam MZ,Buell DN

    更新日期:1993-04-01 00:00:00

  • Trajectories of life-space mobility after hospitalization.

    abstract:BACKGROUND:Life space is a measure of where a person goes, the frequency of going there, and the dependency in getting there. It may be a more accurate measure of mobility in older adults because it reflects participation in society as well as physical ability. OBJECTIVE:To assess effects of hospitalization on life sp...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-150-6-200903170-00005

    authors: Brown CJ,Roth DL,Allman RM,Sawyer P,Ritchie CS,Roseman JM

    更新日期:2009-03-17 00:00:00

  • Trace elements and blood pressure.

    abstract::Essential trace elements such as zinc, iron, and copper participate in various enzyme reactions directly related to the regulation of blood pressure and indirectly related to generation of oxidative metabolic energy, alterations in blood lipid levels, and alterations in taste acuity. The toxicological action of severa...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-98-5-823

    authors: Saltman P

    更新日期:1983-05-01 00:00:00

  • Thyroid autoimmunity: increased frequency in relatives of insulin-dependent diabetes patients.

    abstract::Thyroid antibodies were found significantly more often in insulin-dependent diabetics than in their spouses or in non-insulin-dependent diabetics. The poor correlation between presence of thyroid autoimmunity and duration of disease and the significantly increased prevalence of thyroid antibodies in first-degree relat...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-83-2-170

    authors: Fialkow PJ,Zavala C,Nielsen R

    更新日期:1975-08-01 00:00:00

  • Causes of death in homeless adults in Boston.

    abstract:BACKGROUND:Homeless persons have high mortality rates. OBJECTIVE:To ascertain causes of death in a group of homeless persons. DESIGN:Cohort study. PATIENTS:17,292 adults seen by the Boston Health Care for the Homeless Program from 1988 to 1993. MEASUREMENTS:Cause-specific mortality rates adjusted for race and rate ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-126-8-199704150-00007

    authors: Hwang SW,Orav EJ,O'Connell JJ,Lebow JM,Brennan TA

    更新日期:1997-04-15 00:00:00

  • "Comparably massive" penicillin G therapy in renal failure.

    abstract::Impairment of penicillin G excretion in renal failure may result in life-threatening, dose-related toxicity. We report a method for achieving a desired mean serum penicillin G concentration in patients with renal failure, with minimal risk of both undertreatment and drug toxicity. The method is based on the linear rel...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-82-2-189

    authors: Bryan CS,Stone WJ

    更新日期:1975-02-01 00:00:00

  • The Financial Effect of Value-Based Purchasing and the Hospital Readmissions Reduction Program on Safety-Net Hospitals in 2014: A Cohort Study.

    abstract:BACKGROUND:Medicare's value-based purchasing (VBP) and the Hospital Readmissions Reduction Program (HRRP) could disproportionately affect safety-net hospitals. OBJECTIVE:To determine whether safety-net hospitals incur larger financial penalties than other hospitals under VBP and HRRP. DESIGN:Cross-sectional analysis....

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/M14-2813

    authors: Gilman M,Hockenberry JM,Adams EK,Milstein AS,Wilson IB,Becker ER

    更新日期:2015-09-15 00:00:00

  • Reactivation of chronic hepatitis B virus infection by cancer chemotherapy.

    abstract::Two patients referred for cancer chemotherapy were found to be chronic, asymptomatic hepatitis B surface antigen (HBsAg) carriers. They had normal serum aminotransferase levels, but their sera were positive for HGsAg and antibody to hepatitis B e antigen. Both patients developed acute, icteric hepatitis within 3 month...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-96-4-447

    authors: Hoofnagle JH,Dusheiko GM,Schafer DF,Jones EA,Micetich KC,Young RC,Costa J

    更新日期:1982-04-01 00:00:00

  • Have we treated AIDS too well? Rationing and the future of AIDS exceptionalism.

    abstract::During the past decade, medical therapy for AIDS has become more effective but also prohibitively expensive. A medical tragedy has been transformed into a financial crisis, and society has responded by establishing special programs and sources of funding for AIDS. These maneuvers parallel earlier approaches to HIV tes...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-128-9-199805010-00009

    authors: Casarett DJ,Lantos JD

    更新日期:1998-05-01 00:00:00

  • Recommendations for caring for patients with severe and nonsevere COVID-19.

    abstract:SOURCE CITATION:Ye Z, Rochwerg B, Wang Y, et al. Treatment of patients with nonsevere and severe coronavirus disease 2019: an evidence-based guideline. CMAJ. 2020;192:E536-45. 32350002. ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/ACPJ202007210-004

    authors: Paladugu S,Donato AA

    更新日期:2020-07-21 00:00:00

  • Sleep and sleep disorders in pregnancy.

    abstract::Sleep problems are common in pregnant women. This review examines sleep in normal pregnancy; discusses the physiologic bases for alterations in sleep, including hormonal and mechanical factors; and correlates these factors with changes in sleep of pregnant women, as determined subjectively by surveys and objectively b...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-134-5-200103060-00012

    authors: Santiago JR,Nolledo MS,Kinzler W,Santiago TV

    更新日期:2001-03-06 00:00:00

  • Cocaine use and the risk for endocarditis in intravenous drug users.

    abstract::Endocarditis is a relatively frequent infection in intravenous drug users. We compared features in the cases of 102 patients with those in intravenous drug users with other causes of fever to identify risk factors predictive of endocarditis. Logistic regression analysis showed cocaine use to be strongly associated wit...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-106-6-833

    authors: Chambers HF,Morris DL,Täuber MG,Modin G

    更新日期:1987-06-01 00:00:00