Clinically silent atrial septal defects with evidence for cerebral embolization.

abstract：:Physician performance failures are not rare and pose substantial threats to patient welfare and safety. Few hospitals respond to such failures promptly or effectively. Failure to ensure the quality and safety of the performance of colleagues is a breach of medicine's fiduciary responsibility to the public. A major rea...

journal_title：Annals of internal medicine

authors： Leape LL,Fromson JA

更新日期：2006-01-17 00:00:00

abstract：OBJECTIVE:To determine the most effective and safe dose of enoxaparin to prevent deep venous thrombosis in high-risk surgical patients. DESIGN:A double-blind, randomized, multicenter clinical trial. SETTING:Private, university, and government hospitals in the United States. PATIENTS:572 patients having elective hip ...

journal_title：Annals of internal medicine

authors： Spiro TE,Johnson GJ,Christie MJ,Lyons RM,MacFarlane DE,Blasier RB,Tremaine MD

更新日期：1994-07-15 00:00:00

abstract：OBJECTIVE:To determine whether laboratory findings showing antibodies to hepatitis C virus (HCV) in patients with autoimmune hepatitis represent false-positive results and to identify possible explanations for true-positive results in these patients. DESIGN:Cross-sectional. SETTING:University-based hospital. PATIENT...

journal_title：Annals of internal medicine

authors： Nishiguchi S,Kuroki T,Ueda T,Fukuda K,Takeda T,Nakajima S,Shiomi S,Kobayashi K,Otani S,Hayashi N

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Recently, liver transplantation has been used to treat patients with familial amyloid polyneuropathy (FAP). OBJECTIVE:To describe the clinical course of patients with FAP who received partial-liver transplantation from living donors. DESIGN:Case series. SETTING:University hospital in Matsumoto, Japan. PA...

journal_title：Annals of internal medicine

authors： Takei Y,Ikeda S,Hashikura Y,Ikegami T,Kawasaki S

更新日期：1999-10-19 00:00:00

abstract：:With the renewed interest in esophageal motility disorders, diffuse esophageal spasm is being diagnosed more frequently. In many clinical settings, however, the term is used as a synonym for noncardiac chest pain. Our review of the literature and broad clinical experience in studying the motility patterns of healthy s...

journal_title：Annals of internal medicine

authors： Richter JE,Castell DO

更新日期：1984-02-01 00:00:00

abstract：UNLABELLED:Chinese translation BACKGROUND:Black persons are more likely than white persons to be diagnosed with colorectal cancer and to die from it. The extent to which genetic or biological factors versus disparities in screening rates explain this variance remains controversial. OBJECTIVE:To define the prevalence ...

journal_title：Annals of internal medicine

authors： Schroy PC 3rd,Coe A,Chen CA,O'Brien MJ,Heeren TC

更新日期：2013-07-02 00:00:00

abstract：BACKGROUND:Soon, half of all physicians may be married to other physicians (that is, in dual-doctor families). Little is known about how marriage to another physician affects physicians themselves. OBJECTIVE:To learn how physicians in dual-doctor families differ from other physicians in their professional and family l...

journal_title：Annals of internal medicine

authors： Sobecks NW,Justice AC,Hinze S,Chirayath HT,Lasek RJ,Chren MM,Aucott J,Juknialis B,Fortinsky R,Youngner S,Landefeld CS

更新日期：1999-02-16 00:00:00

abstract：OBJECTIVE:To evaluate the relation between weight variability and death in high-risk, middle-aged men participating in the Multiple Risk Factor Intervention Trial (MRFIT). DESIGN:Cohort study with 3.8 years of follow-up. SETTING:Multicenter, collaborative, primary prevention trial conducted at 22 clinical centers in ...

journal_title：Annals of internal medicine

authors： Blair SN,Shaten J,Brownell K,Collins G,Lissner L

更新日期：1993-10-01 00:00:00

abstract：:In studies of the cause of gastrointestinal symptoms in homosexual men, Campylobacter jejuni was recovered from 10 of 158 men with, and 2 of 75 men without, intestinal symptoms. In addition, a heterogeneous group of Campylobacter-like organisms was identified in 26 symptomatic and 6 asymptomatic homosexual men, but in...

journal_title：Annals of internal medicine

authors： Quinn TC,Goodell SE,Fennell C,Wang SP,Schuffler MD,Holmes KK,Stamm WE

更新日期：1984-08-01 00:00:00

abstract：:The sharp rise in drug abuse in the past decade has led to the development of new sources of information on drug-abuse trends. These include surveys, drug-related emergencies, drug-abuse treatment, hepatitis rates, and various types of law enforcement information. This paper summarizes data currently available for her...

journal_title：Annals of internal medicine

authors： Greene MH,Nightingale SL,DuPont RL

更新日期：1975-09-01 00:00:00

abstract：:Clinical and epidemiologic characteristics of disease associated with a newly described nonhalophilic Vibrio species, Vibrio mimicus, were identified by studying isolates from 21 patients referred to the Centers for Disease Control between 1977 and 1981. Two isolates were from the ears of patients with otitis who had ...

journal_title：Annals of internal medicine

authors： Shandera WX,Johnston JM,Davis BR,Blake PA

更新日期：1983-08-01 00:00:00

abstract：:Patients with variant angina refractory to medical therapy pose a difficult management problem. We report two patients with variant angina who had focal spasm in coronary arteries with fixed obstructions of less than 20% of the luminal diameter. Ischemic episodes were accompanied by malignant ventricular arrhythmias a...

journal_title：Annals of internal medicine

authors： Sussman EJ,Goldberg S,Poll DS,MacVaugh H 3rd,Simson MB,Silber SA,Kastor JA

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND:Although few retrospective studies of high altitude have reported that obesity might be associated with the development of acute mountain sickness (AMS), this association has not been studied prospectively. OBJECTIVE:To determine whether obesity is associated with the development of AMS. DESIGN:Obese and n...

journal_title：Annals of internal medicine

authors： Ri-Li G,Chase PJ,Witkowski S,Wyrick BL,Stone JA,Levine BD,Babb TG

更新日期：2003-08-19 00:00:00

abstract：:Our review focuses on low density lipoprotein (LD lipoprotein) and very low density lipoprotein (VLD lipoprotein) in their roles as transporters of cholesterol and triglyceride and as factors contributing to premature arteriovascular disease. We describe the clinical manifestations of the common, primary hyperlipoprot...

journal_title：Annals of internal medicine

authors： Fisher WR,Truitt DH

更新日期：1976-10-01 00:00:00

abstract：BACKGROUND:Endoscopic retrograde cholangiopancreatography (ERCP) is a technically demanding procedure that can cause substantial complications. Competence in performing ERCP and the learning curve for achieving competence are poorly understood. OBJECTIVE:To evaluate the number of supervised ERCPs that physicians must ...

journal_title：Annals of internal medicine

authors： Jowell PS,Baillie J,Branch MS,Affronti J,Browning CL,Bute BP

更新日期：1996-12-15 00:00:00

abstract：OBJECTIVE:To measure changes in spinal and femoral neck bone mineral densities in patients treated for Graves thyrotoxicosis. DESIGN:Cohort study. SETTING:Tertiary care center. PATIENTS:Fifteen women with active Graves thyrotoxicosis. Six patients were premenopausal and nine were postmenopausal. All patients had evi...

journal_title：Annals of internal medicine

authors： Diamond T,Vine J,Smart R,Butler P

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:To investigate the relation between the quantity of human immunodeficiency virus type 1 (HIV-1) RNA in plasma and the risk for the acquired immunodeficiency syndrome (AIDS) or a decline in the CD4+ T-cell count after seroconversion. DESIGN:Prospective study. PATIENTS:62 homosexual men with documented HIV-1 ...

journal_title：Annals of internal medicine

authors： Mellors JW,Kingsley LA,Rinaldo CR Jr,Todd JA,Hoo BS,Kokka RP,Gupta P

更新日期：1995-04-15 00:00:00

abstract：:Three patients with advanced Graves' ophthalmopathy were treated with cyclophosphamide. All had proptosis and diplopia. One patient had disabling iatrogenic Cushing's syndrome from steroid treatment of the ophthalmopathy and had undergone bilateral orbital decompression before cyclophosphamide therapy; steroids could ...

journal_title：Annals of internal medicine

authors： Bigos ST,Nisula BC,Daniels GH,Eastman RC,Johnston HH,Kohler PO

更新日期：1979-06-01 00:00:00

abstract：:Differences in blood levels of thyroid hormones have been reported when patients taking synthetic L-thyroxine were shifted from one manufactured form of the hormone to another. Because recent formulation changes have rendered these earlier data obsolete, we did a crossover study to determine differences in bioavailabi...

journal_title：Annals of internal medicine

authors： Hennessey JV,Burman KD,Wartofsky L

更新日期：1985-06-01 00:00:00

abstract：:Implantable cardioverter defibrillators are life-saving devices for many patients with cardiac disease. Recipients of these devices, nevertheless, often suffer from progressive comorbid and cardiac conditions. Therefore, physicians should anticipate situations in which the defibrillator is no longer desired by the pat...

journal_title：Annals of internal medicine

authors： Berger JT

更新日期：2005-04-19 00:00:00

abstract：:More than 18 million Americans currently have diabetes mellitus. The economic and human cost of the disease is devastating. In the United States, diabetes is the most common cause of blindness among working-age adults, the most common cause of nontraumatic amputations and end-stage renal disease, and the sixth most co...

journal_title：Annals of internal medicine

authors： Williamson DF,Vinicor F,Bowman BA,Centers For Disease Control And Prevention Primary Prevention Working Group.

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:The Department of Health and Human Services recently called for public comment on human subjects research protections. OBJECTIVE:To assess variability in reviews across institutional review boards (IRBs) for a multisite, minimal-risk trial of financial incentives for evidence-based hypertension care and to ...

journal_title：Annals of internal medicine

authors： Petersen LA,Simpson K,Sorelle R,Urech T,Chitwood SS

更新日期：2012-05-15 00:00:00

abstract：:Transmission of the human immunodeficiency virus (HIV) was studied in a group of patients with cancer who received transfusion of blood components harvested from a single, asymptomatic, seropositive donor. Of ten living recipients, nine had antibodies to the virus in fresh or cryopreserved sera at a median of 384 days...

journal_title：Annals of internal medicine

authors： Anderson KC,Gorgone BC,Marlink RG,Ferriani R,Essex ME,Benz PM,Groopman JE

更新日期：1986-10-01 00:00:00

abstract：:Advances through basic research have elucidated the disturbances of neurotransmitter function in Parkinson's Dopamine has replaced acetylcholine and norepinephrine as the most studied neurotransmitter, with both conceptual and practical developments, exemplified by the hypothesis of cyclic adenosine monophosphate as a...

journal_title：Annals of internal medicine

authors： Calne DB,Kebabian J,Silbergeld E,Evarts E

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:Extended-duration low-molecular-weight heparin has been shown to prevent venous thromboembolism (VTE) in high-risk surgical patients. OBJECTIVE:To evaluate the efficacy and safety of extended-duration enoxaparin thromboprophylaxis in acutely ill medical patients. DESIGN:Randomized, parallel, placebo-contro...

journal_title：Annals of internal medicine

authors： Hull RD,Schellong SM,Tapson VF,Monreal M,Samama MM,Nicol P,Vicaut E,Turpie AG,Yusen RD,EXCLAIM (Extended Prophylaxis for Venous ThromboEmbolism in Acutely Ill Medical Patients With Prolonged Immobilization) study.

更新日期：2010-07-06 00:00:00

abstract：OBJECTIVE:To describe the course of rheumatoid arthritis over 5 years in adults and to evaluate the effect of parenterally administered gold salts on that course. DESIGN:A prospective observational study of adults with rheumatoid arthritis. Data derived from annual interviews with patients from 1983 to 1988 and from p...

journal_title：Annals of internal medicine

authors： Epstein WV,Henke CJ,Yelin EH,Katz PP

更新日期：1991-03-15 00:00:00

abstract：OBJECTIVE:To evaluate the relation between skeletal muscle disease (myopathy) and degenerative changes in cardiac muscle (cardiomyopathy) in patients with chronic alcoholism. DESIGN:A cross-sectional study. SETTING:University medical center. PARTICIPANTS:Group A included 24 patients with chronic alcoholism who had d...

journal_title：Annals of internal medicine

authors： Fernandez-Sola J,Estruch R,Grau JM,Pare JC,Rubin E,Urbano-Marquez A

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Although several agents are available to treat osteoporosis, the relative efficacy and toxicity of these agents when used to prevent fractures has not been well described. PURPOSE:To compare the benefits in fracture reduction and the harms from adverse events of various therapies for osteoporosis. DATA SOU...

journal_title：Annals of internal medicine

authors： MacLean C,Newberry S,Maglione M,McMahon M,Ranganath V,Suttorp M,Mojica W,Timmer M,Alexander A,McNamara M,Desai SB,Zhou A,Chen S,Carter J,Tringale C,Valentine D,Johnsen B,Grossman J

更新日期：2008-02-05 00:00:00

abstract：BACKGROUND:Patients with reduced left ventricular function and ventricular enlargement after myocardial infarction are at significantly greater risk for congestive heart failure and death. Nevertheless, recovery of ventricular function occurs in a significant proportion of patients after myocardial infarction, and mode...

journal_title：Annals of internal medicine

authors： Solomon SD,Glynn RJ,Greaves S,Ajani U,Rouleau JL,Menapace F,Arnold JM,Hennekens C,Pfeffer MA

更新日期：2001-03-20 00:00:00

abstract：OBJECTIVE:To identify the cause of a hypersensitivity pneumonitis and to determine its pathogenesis. DESIGN:Case study. SETTING:Intensive care unit of a referral hospital. PATIENT:A 51-year-old man with chronic bronchitis who developed a hypersensitivity pneumonitis within 1 month after exposure to minocycline, amox...

journal_title：Annals of internal medicine

authors： Guillon JM,Joly P,Autran B,Denis M,Akoun G,Debré P,Mayaud C

更新日期：1992-09-15 00:00:00