Advances in the neuropharmacology of Parkinsonism.

abstract：PURPOSE:To develop a clinical perspective on bilateral massive adrenal hemorrhage and an algorithm for its diagnosis and treatment. DATA IDENTIFICATION:Case reports were identified through a computer search using MEDLIN (1976 to 1987), and from bibliographies in review articles (up to 1978). STUDY SELECTION:Twelve re...

journal_title：Annals of internal medicine

authors： Rao RH,Vagnucci AH,Amico JA

更新日期：1989-02-01 00:00:00

abstract：OBJECTIVE:To determine whether concurrent treatment with acetaminophen and zidovudine impairs clearance of zidovudine, thereby increasing the risk for zidovudine-induced hematologic toxicity. DESIGN:Dose escalation, drug interaction study. SETTING:University clinical research center. PATIENTS:Patients with the acqui...

journal_title：Annals of internal medicine

authors： Sattler FR,Ko R,Antoniskis D,Shields M,Cohen J,Nicoloff J,Leedom J,Koda R

更新日期：1991-06-01 00:00:00

abstract：:Two patients presenting with nephrotic syndrome but without evidence of collagen vascular disease had organized glomerular immune deposits with a "fingerprint" pattern. This finding has been previously associated with lupus nephritis and, in our institution, has been seen in 6% of the biopsy specimens from patients wi...

journal_title：Annals of internal medicine

authors： Alpers CE,Hopper J Jr,Bernstein MJ,Biava CG

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:To determine the following: a reference range for serum calcitriol during hypercalcemia in a control group of patients with myeloma in whom calcitriol production is known to be appropriately suppressed; the incidence of elevated serum calcitriol levels in hypercalcemic patients with non-Hodgkin lymphoma accor...

journal_title：Annals of internal medicine

authors： Seymour JF,Gagel RF,Hagemeister FB,Dimopoulos MA,Cabanillas F

更新日期：1994-11-01 00:00:00

abstract：:Tissues from guinea pigs inoculated intraperitoneally with the Legionnaires' disease (LD) bacterium were studied with light, immunofluorescent, and electron microscopy. The principal gross lesion was diffuse peritonitis of varying severity. Microscopically, the peritonitis of covered by a mixed inflammatory infiltrate...

journal_title：Annals of internal medicine

authors： Chandler FW,McDade JE,Hicklin MD,Blackmon JA,Thomason BM,Ewing EP Jr

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:Pharmacologic thromboprophylaxis reduces the risk for venous thromboembolism after total hip replacement (THR) or total knee replacement (TKR). New oral anticoagulants (NOACs), including direct thrombin inhibitors and factor Xa inhibitors, are emerging options for thromboprophylaxis after these procedures. ...

journal_title：Annals of internal medicine

authors： Adam SS,McDuffie JR,Lachiewicz PF,Ortel TL,Williams JW Jr

更新日期：2013-08-20 00:00:00

abstract：:To understand the factors that distinguish terminally ill, incompetent patients who are given do-not-resuscitate status by physicians against the wishes of the patient's family, I reviewed the charts of 20 such patients (cases) seen in consultation by the ethics committee at the Massachusetts General Hospital over 10 ...

journal_title：Annals of internal medicine

authors： Brennan TA

更新日期：1988-11-15 00:00:00

abstract：BACKGROUND:The renin-angiotensin system is involved in adipocyte growth and differentiation and possibly in adipose tissue metabolism. OBJECTIVE:To investigate the association of polymorphism in the angiotensin-converting enzyme (ACE) I/D gene, angiotensinogen M235T gene, and angiotensin II type 1 receptor A1166C gene...

journal_title：Annals of internal medicine

authors： Strazzullo P,Iacone R,Iacoviello L,Russo O,Barba G,Russo P,D'Orazio A,Barbato A,Cappuccio FP,Farinaro E,Siani A,Olivetti Prospective Heart Study.

更新日期：2003-01-07 00:00:00

abstract：OBJECTIVE:To evaluate the amount of variation in in-hospital mortality and length of intensive care unit (ICU) stay that can be accounted for by clinical data available at ICU admission. DESIGN:Inception cohort study. SETTING:Forty-two ICUs in 40 hospitals, including 26 hospitals that were randomly selected and 14 la...

journal_title：Annals of internal medicine

authors： Knaus WA,Wagner DP,Zimmerman JE,Draper EA

更新日期：1993-05-15 00:00:00

abstract：PURPOSE:Chemoprevention offers promise as a strategy for reducing morbidity and mortality from breast cancer in women. This review examined the evidence for the effectiveness of chemoprevention in women without a history of breast cancer. DATA SOURCES:MEDLINE (1966 to December 2001). STUDY SELECTION:English-language,...

journal_title：Annals of internal medicine

authors： Kinsinger LS,Harris R,Woolf SH,Sox HC,Lohr KN

更新日期：2002-07-02 00:00:00

abstract：OBJECTIVE:To determine the frequency of tests done in the year before elective surgery that might substitute for preoperative screening tests and to determine the frequency of test results that change from a normal value to a value likely to alter perioperative management. DESIGN:Retrospective cohort analysis of compu...

journal_title：Annals of internal medicine

authors： Macpherson DS,Snow R,Lofgren RP

更新日期：1990-12-15 00:00:00

abstract：BACKGROUND:Exercise therapy encompasses a heterogeneous group of interventions. There continues to be uncertainty about the most effective exercise approach in chronic low back pain. PURPOSE:To identify particular exercise intervention characteristics that decrease pain and improve function in adults with nonspecific ...

journal_title：Annals of internal medicine

authors： Hayden JA,van Tulder MW,Tomlinson G

更新日期：2005-05-03 00:00:00

abstract：BACKGROUND:Clinical trial registries are in widespread use to promote transparency around trials and their results. OBJECTIVE:To describe characteristics of drug trials listed in ClinicalTrials.gov and examine whether the funding source of these trials is associated with favorable published outcomes. DESIGN:An observ...

journal_title：Annals of internal medicine

authors： Bourgeois FT,Murthy S,Mandl KD

更新日期：2010-08-03 00:00:00

abstract：:The Biblical Book of Job is a wisdom book. Wisdom, in this context, refers to the intellectual discipline taught by the sages of ancient Isreael to provide professionals with a realistic approach to the problems of life. Chapter 30 of the Book of Job is a key-index of ideas that, if followed through the book, disclose...

journal_title：Annals of internal medicine

authors： Kapusta MA,Frank S

更新日期：1977-05-01 00:00:00

abstract：OBJECTIVE:To assess the safety and efficacy of intravenous adenosine in terminating acute episodes of paroxysmal supraventricular tachycardia. DESIGN:Two prospective, double-blind, randomized, placebo-controlled trials to evaluate dose response in patients receiving adenosine and to compare the effects of adenosine wi...

journal_title：Annals of internal medicine

authors： DiMarco JP,Miles W,Akhtar M,Milstein S,Sharma AD,Platia E,McGovern B,Scheinman MM,Govier WC

更新日期：1990-07-15 00:00:00

abstract：:A patient with a retained bullet developed lead poisoning in association with thyrotoxicosis. The clinical and laboratory data suggest that lead was mobilized from an increased mobile bone pool during the hypermetabolic period with resultant poisoning. The findings give factual support to earlier concepts that lead po...

journal_title：Annals of internal medicine

authors： Cagin CR,Diloy-Puray M,Westerman MP

更新日期：1978-10-01 00:00:00

abstract：:Disseminated candidiasis has become an important infection, particularly in immunocompromised and postoperative patients. Although serologic tests may, in some settings, facilitate a premortem diagnosis, the disease is usually diagnosed by comprehensive clinical evaluation. Detection of the relatively newly recognized...

journal_title：Annals of internal medicine

authors： Edwards JE Jr,Lehrer RI,Stiehm ER,Fischer TJ,Young LS

更新日期：1978-07-01 00:00:00

abstract：:There has been considerable change in the practice of internal medicine in the past quarter century, including the rise of specialization, increasing time pressure, the hospitalist movement, and the rapidly changing responsibilities of internists in inpatient and outpatient settings. Training programs have not adequat...

journal_title：Annals of internal medicine

authors： Association of Program Directors in Internal Medicine.,Fitzgibbons JP,Bordley DR,Berkowitz LR,Miller BW,Henderson MC

更新日期：2006-06-20 00:00:00

abstract：:Care of persons with non-insulin-dependent diabetes mellitus (NIDDM) in the United Kingdom resembles that in the United States. However, health care practice in Europe is being influenced by the Saint Vincent Declaration, the joint European World Health Organization-International Diabetes Federation initiative, which ...

journal_title：Annals of internal medicine

authors： Keen H

更新日期：1996-01-01 00:00:00

abstract：:A patient with familial Mediterranean fever and amyloidosis who received a cadaver renal transplant 6 1/2 years ago was studied to determine the relation of the serum precursor of secondary amyloid (SAA) to the clinical course and to the deposition of amyloid in the transplant. Amyloid fibrils extracted from the patie...

journal_title：Annals of internal medicine

authors： Benson MD,Skinner M,Cohen AS

更新日期：1977-07-01 00:00:00

abstract：PURPOSE:To review the literature on prevention of intravascular catheter-related infections. DATA SOURCES:The MEDLINE database, conference proceedings, and bibliographies of review articles and book chapters were searched for relevant articles. Primary authors were contacted directly if data were incomplete. STUDY SE...

journal_title：Annals of internal medicine

authors： Mermel LA

更新日期：2000-03-07 00:00:00

abstract：:Twenty-one juvenile-onset diabetic patients with azotemic nephropathy underwent coronary angiography and left ventriculography before renal transplantation or chronic hemodialysis. Two-year survival of 12 patients with no coronary artery disease (group A) was 88% compared to 22% for nine patients with coronary artery ...

journal_title：Annals of internal medicine

authors： Weinrauch LA,D'elia JA,Healy RW,Gleason RE,Takacs FJ,Libertino JA,Leland OS

更新日期：1978-03-01 00:00:00

abstract：:Amantadine HCl administration has resulted in accelerated resolution of influenza A illness. Prolonged abnormalities in pulmonary function have been described in uncomplicated influenza A. To study the effect of amantadine on these changes, we evaluated young adults with documented natural influenza A with clear chest...

journal_title：Annals of internal medicine

authors： Little JW,Hall WJ,Douglas RG Jr,Hyde RW,Speers DM

更新日期：1976-08-01 00:00:00

abstract：OBJECTIVE:To provide a rational strategy for the evaluation and long-term management of epilepsy. DATA SOURCES:Articles written between 1964 and 1993, obtained from a MEDLINE search on epilepsy-related topics as well as from the author's personal files, major reference books on antiepileptic drugs, and references iden...

journal_title：Annals of internal medicine

authors： French J

更新日期：1994-03-01 00:00:00

abstract：:Two patients with profound decrease of alpha1-antitrypsin (PiZZ) presented with severe pannicultis (Weber-Christian disease); one had systemic panniculitis including pancreatitis. Another possible case is quoted from the literature. Although milder forms of panniculitis can have normal Pi phenotypes and alpha1-antitry...

journal_title：Annals of internal medicine

authors： Rubinstein HM,Jaffer AM,Kudrna JC,Lertratanakul Y,Chandrasekhar AJ,Slater D,Schmid FR

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:No regulations govern placebo composition. The composition of placebos can influence trial outcomes and merits reporting. PURPOSE:To assess how often investigators specify the composition of placebos in randomized, placebo-controlled trials. DATA SOURCES:4 English-language general and internal medicine jou...

journal_title：Annals of internal medicine

authors： Golomb BA,Erickson LC,Koperski S,Sack D,Enkin M,Howick J

更新日期：2010-10-19 00:00:00

abstract：:Sixty-eight patients clinically suspected of having (33), or at high risk for (35), deep venous thrombosis were studied with contrast venography, radiofibrinogen leg scanning, and impedance plethysmography as well as ventilation and perfusion lung scans. Thrombosis limited to the veins in the calf of the leg (unilater...

journal_title：Annals of internal medicine

authors： Moser KM,LeMoine JR

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND:Although weight loss improves risk factors for cardiovascular and metabolic disease, it is unclear whether intentional weight loss reduces mortality rates. OBJECTIVE:To examine the relationships among intention to lose weight, weight loss, and all-cause mortality. DESIGN:Prospective cohort study using a pr...

journal_title：Annals of internal medicine

authors： Gregg EW,Gerzoff RB,Thompson TJ,Williamson DF

更新日期：2003-03-04 00:00:00

abstract：:Increased adrenocorticotropic hormone (ACTH) levels after bilateral adrenalectomy could be secondary to a pituitary tumor, under replacement with cortisol, or an abnormality in the hypothalamic-pituitary-adrenal feedback loop. To distinguish between these possibilities, ACTH levels were measured before and after corti...

journal_title：Annals of internal medicine

authors： Koletsky RJ,Dluhy RG,Crantz FR,Williams GH

更新日期：1982-03-01 00:00:00

abstract：:We prospectively studied the evaluation of dementia in 107 unselected outpatients; 83 had so-called "irreversible" dementias, including 74 who had an Alzheimer-type dementia. Fifteen patients had potentially reversible dementias, of which hypothyroidism and drug toxicity were the commonest causes. Distinguishing featu...

journal_title：Annals of internal medicine

authors： Larson EB,Reifler BV,Featherstone HJ,English DR

更新日期：1984-03-01 00:00:00