Alpha1-antitrypsin deficiency with severe panniculitis. Report of two cases.

Abstract:

:Two patients with profound decrease of alpha1-antitrypsin (PiZZ) presented with severe pannicultis (Weber-Christian disease); one had systemic panniculitis including pancreatitis. Another possible case is quoted from the literature. Although milder forms of panniculitis can have normal Pi phenotypes and alpha1-antitrypsin levels, the marked reduction of antiproteolytic activity found in PiZZ homozygotes may predispose to or aggravate the lesions of Weber-Christian disease.

journal_name

Ann Intern Med

authors

Rubinstein HM,Jaffer AM,Kudrna JC,Lertratanakul Y,Chandrasekhar AJ,Slater D,Schmid FR

doi

10.7326/0003-4819-86-6-742

subject

Has Abstract

pub_date

1977-06-01 00:00:00

pages

742-4

issue

6

eissn

0003-4819

issn

1539-3704

journal_volume

86

pub_type

杂志文章
  • Transaminase elevations in patients receiving bovine or porcine heparin.

    abstract::Eighty-six patients who required heparin therapy were randomly assigned to receive bovine or porcine heparin. Abnormal concentrations of alanine transaminase and aspartate transaminase developed during treatment in 59.3% and 26.7% of patients, respectively. Patient characteristics that significantly influenced the dev...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.7326/0003-4819-100-5-646

    authors: Dukes GE Jr,Sanders SW,Russo J Jr,Swenson E,Burnakis TG,Saffle JR,Warden GD

    更新日期:1984-05-01 00:00:00

  • Low-dose chest CT had 95% sensitivity and 91% specificity for diagnosing COVID-19 in patients with clinical symptoms.

    abstract:SOURCE CITATION:Schulze-Hagen M, Hübel C, Meier-Schroers M, et al. Low-dose chest CT for the diagnosis of COVID-19. Dtsch Arztebl Int. 2020;117:389-95. 32762834. ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,多中心研究

    doi:10.7326/ACPJ202012150-068

    authors: Long B

    更新日期:2020-12-15 00:00:00

  • Effect of parenterally administered gold therapy on the course of adult rheumatoid arthritis.

    abstract:OBJECTIVE:To describe the course of rheumatoid arthritis over 5 years in adults and to evaluate the effect of parenterally administered gold salts on that course. DESIGN:A prospective observational study of adults with rheumatoid arthritis. Data derived from annual interviews with patients from 1983 to 1988 and from p...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-114-6-437

    authors: Epstein WV,Henke CJ,Yelin EH,Katz PP

    更新日期:1991-03-15 00:00:00

  • 9-(1,3-Dihydroxy-2-propoxymethyl)guanine (ganciclovir) in the treatment of cytomegalovirus gastrointestinal disease with the acquired immunodeficiency syndrome.

    abstract::9-(1,3-dihydroxy-2-propoxymethyl) guanine (ganciclovir) was used to treat 41 patients (median age, 37 years) with the acquired immunodeficiency syndrome and cytomegalovirus gastrointestinal infection. Sites of infection were the colon in 31, the esophagus in 5, the rectum in 4, and the small bowel in 1. Patients recei...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-107-2-133

    authors: Chachoua A,Dieterich D,Krasinski K,Greene J,Laubenstein L,Wernz J,Buhles W,Koretz S

    更新日期:1987-08-01 00:00:00

  • Recovery of ventricular function after myocardial infarction in the reperfusion era: the healing and early afterload reducing therapy study.

    abstract:BACKGROUND:Patients with reduced left ventricular function and ventricular enlargement after myocardial infarction are at significantly greater risk for congestive heart failure and death. Nevertheless, recovery of ventricular function occurs in a significant proportion of patients after myocardial infarction, and mode...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.7326/0003-4819-134-6-200103200-00009

    authors: Solomon SD,Glynn RJ,Greaves S,Ajani U,Rouleau JL,Menapace F,Arnold JM,Hennekens C,Pfeffer MA

    更新日期:2001-03-20 00:00:00

  • D-dimer for the exclusion of acute venous thrombosis and pulmonary embolism: a systematic review.

    abstract:BACKGROUND:Despite extensive literature, the diagnostic role of d-dimer for deep venous thrombosis (DVT) or pulmonary embolism (PE) remains unclear, reflecting multiple d-dimer assays and concerns about differing sensitivities and variability. PURPOSE:To systematically review trials that assessed sensitivity, specific...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.7326/0003-4819-140-8-200404200-00005

    authors: Stein PD,Hull RD,Patel KC,Olson RE,Ghali WA,Brant R,Biel RK,Bharadia V,Kalra NK

    更新日期:2004-04-20 00:00:00

  • The common hyperlipoproteinemias: an understanding of disease mechanisms and their control.

    abstract::Our review focuses on low density lipoprotein (LD lipoprotein) and very low density lipoprotein (VLD lipoprotein) in their roles as transporters of cholesterol and triglyceride and as factors contributing to premature arteriovascular disease. We describe the clinical manifestations of the common, primary hyperlipoprot...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-85-4-497

    authors: Fisher WR,Truitt DH

    更新日期:1976-10-01 00:00:00

  • Is there a role for maintaining sinus rhythm in patients with atrial fibrillation?

    abstract::Recent studies have indicated that outcomes in patients with atrial fibrillation who are managed with rate control and anticoagulation are similar to those in patients who have maintenance of sinus rhythm. These studies did not include important groups of patients with atrial fibrillation in whom antiarrhythmic therap...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-141-9-200411020-00015

    authors: Zimetbaum P,Josephson ME

    更新日期:2004-11-02 00:00:00

  • Effects of diet and sodium intake on blood pressure: subgroup analysis of the DASH-sodium trial.

    abstract:BACKGROUND:Initial findings from the Dietary Approaches to Stop Hypertension (DASH)-Sodium Trial demonstrated that reduction of sodium intake in two different diets decreased blood pressure in participants with and without hypertension. OBJECTIVE:To determine effects on blood pressure of reduced sodium intake and the ...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.7326/0003-4819-135-12-200112180-00005

    authors: Vollmer WM,Sacks FM,Ard J,Appel LJ,Bray GA,Simons-Morton DG,Conlin PR,Svetkey LP,Erlinger TP,Moore TJ,Karanja N,DASH-Sodium Trial Collaborative Research Group.

    更新日期:2001-12-18 00:00:00

  • Narrative review: reversible cerebral vasoconstriction syndromes.

    abstract::Reversible cerebral vasoconstriction syndromes (RCVS) comprise a group of diverse conditions, all characterized by reversible multifocal narrowing of the cerebral arteries heralded by sudden (thunderclap), severe headaches with or without associated neurologic deficits. Reversible cerebral vasoconstriction syndromes a...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-146-1-200701020-00007

    authors: Calabrese LH,Dodick DW,Schwedt TJ,Singhal AB

    更新日期:2007-01-02 00:00:00

  • Menopausal hormone therapy for the primary prevention of chronic conditions: a systematic review to update the U.S. Preventive Services Task Force recommendations.

    abstract:BACKGROUND:Menopausal hormone therapy to prevent chronic conditions is currently not recommended because of its adverse effects. PURPOSE:To update evidence about the effectiveness of hormone therapy in reducing risk for chronic conditions and adverse effects, and to examine whether outcomes vary among women in differe...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-157-2-201207170-00466

    authors: Nelson HD,Walker M,Zakher B,Mitchell J

    更新日期:2012-07-17 00:00:00

  • Protruding atheromas in the thoracic aorta and systemic embolization.

    abstract:OBJECTIVE:To determine whether protruding atheromas in the thoracic aorta are a risk factor for systemic embolization. DESIGN:Case-control study. SETTING:A referral hospital. PATIENTS:A total of 122 patients with a history of stroke, transient ischemic attack, or peripheral emboli and an equal number of age- and sex...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-115-6-423

    authors: Tunick PA,Perez JL,Kronzon I

    更新日期:1991-09-15 00:00:00

  • A tuberculostearic acid assay in the diagnosis of sputum smear-negative pulmonary tuberculosis. A prospective study of bronchoscopic aspirate and lavage specimens.

    abstract:OBJECTIVE:To determine whether the detection of tuberculostearic acid (TBSA) in bronchial aspirate and bronchoalveolar lavage specimens is useful for the rapid diagnosis of active pulmonary tuberculosis in patients suspected of having the disease. SETTING:A pulmonary clinic in a teaching hospital. PATIENTS:Forty pati...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-111-8-650

    authors: Pang JA,Chan HS,Chan CY,Cheung SW,French GL

    更新日期:1989-10-15 00:00:00

  • Indications for arterial blood gas analysis.

    abstract::Arterial blood gas analysis is used to evaluate oxygen and carbon dioxide gas exchange and acid-base status. Few studies identify indications for arterial blood gas analysis, especially with regard to optimizing the quality of patient care. General indications in severely ill adults usually include pathophysiologic ab...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-105-3-390

    authors: Raffin TA

    更新日期:1986-09-01 00:00:00

  • Occupationally acquired infections in health care workers. Part I.

    abstract:BACKGROUND:Health care workers are at occupational risk for a vast array of infections that cause substantial illness and occasional deaths. Despite this, few studies have examined the incidence, prevalence, or exposure-associated rates of infection or have considered infection-specific interventions recommended to mai...

    journal_title:Annals of internal medicine

    pub_type: 历史文章,杂志文章,评审

    doi:10.7326/0003-4819-125-10-199611150-00007

    authors: Sepkowitz KA

    更新日期:1996-11-15 00:00:00

  • Bulimarexia and related serious eating disorders with medical complications.

    abstract::Bulimarexia, an eating disorder that is characterized by binge eating followed by self-induced vomiting or abuse of cathartic or diuretic drugs, has been defined as both a sequela of anorexia nervosa and a distinct eating disorder. In this review the presentation, prevalence, and complications of the various eating di...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-99-6-800

    authors: Harris RT

    更新日期:1983-12-01 00:00:00

  • Very low calorie diets: their efficacy, safety, and future.

    abstract::Very low calorie diets used to treat moderate and severe obesity produce average weight losses of 20 kg in 12 weeks. This paper reviews the development of very low calorie diets from research on fasting in the late 1950s and examines data on the amount of dietary protein needed to achieve positive nitrogen balance. Th...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-99-5-675

    authors: Wadden TA,Stunkard AJ,Brownell KD

    更新日期:1983-11-01 00:00:00

  • Computed tomography brain scanning in alcohol withdrawal seizures. Value of the neurologic examination.

    abstract::We evaluated the usefulness of computed tomography (CT) brain scanning in alcoholic patients with withdrawal seizures (n = 151) and other neurologic problems (n = 87) and compared the findings of a detailed neurologic examination to the results of CT scanning. In patients with seizures, nearly 50% of CT scans were nor...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-94-4-519

    authors: Feussner JR,Linfors EW,Blessing CL,Starmer CF

    更新日期:1981-04-01 00:00:00

  • Effects of an intervention to increase bed alarm use to prevent falls in hospitalized patients: a cluster randomized trial.

    abstract:BACKGROUND:Bed alarm systems intended to prevent hospital falls have not been formally evaluated. OBJECTIVE:To investigate whether an intervention aimed at increasing bed alarm use decreases hospital falls and related events. DESIGN:Pair-matched, cluster randomized trial over 18 months. Nursing units were allocated b...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.7326/0003-4819-157-10-201211200-00005

    authors: Shorr RI,Chandler AM,Mion LC,Waters TM,Liu M,Daniels MJ,Kessler LA,Miller ST

    更新日期:2012-11-20 00:00:00

  • Evaluating contrast-enhancing brain lesions in patients with AIDS by using positron emission tomography.

    abstract:OBJECTIVE:To determine whether a noninvasive method for evaluating contrast-enhancing brain lesions in patients with the acquired immunodeficiency syndrome (AIDS) can accurately differentiate between lymphoma and nonlymphoma diagnoses. This method is based on Toxoplasma serologic testing and positron emission tomograph...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-123-8-199510150-00005

    authors: Pierce MA,Johnson MD,Maciunas RJ,Murray MJ,Allen GS,Harbison MA,Creasy JL,Kessler RM

    更新日期:1995-10-15 00:00:00

  • Evaluation of Hospital Performance Using the Excess Days in Acute Care Measure in the Hospital Readmissions Reduction Program.

    abstract::The Hospital Readmissions Reduction Program (HRRP) has penalized hospitals with higher 30-day readmission rates more than $3 billion to date. Clinicians and policy experts have raised concerns that the 30-day readmission measure used in this program provides an incomplete picture of performance because it does not cap...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/M20-3486

    authors: Wadhera RK,Joynt Maddox KE,Desai NR,Landon BE,Md MV,Gilstrap LG,Shen C,Yeh RW

    更新日期:2021-01-01 00:00:00

  • 45-year follow-up of hepatitis C virus infection in healthy young adults.

    abstract:BACKGROUND:The sequelae during the first two decades after acute hepatitis C virus (HCV) infection have been well studied, but the outcome thereafter is unknown. OBJECTIVE:To conduct an extended study of the natural history of HCV infection by using archived serum specimens originally collected between 1948 and 1954. ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-132-2-200001180-00003

    authors: Seeff LB,Miller RN,Rabkin CS,Buskell-Bales Z,Straley-Eason KD,Smoak BL,Johnson LD,Lee SR,Kaplan EL

    更新日期:2000-01-18 00:00:00

  • Acupuncture for chronic shoulder pain. An experimental study with attention to the role of placebo and hypnotic susceptibility.

    abstract::One half of 42 subjects treated for painful shoulders received classic acupuncture, and one half received a placebo in which the needles did not penetrate the skin. Half of each of these groups was treated in a positive setting to encourage the subject, and half in a negative setting designed to keep encouragement at ...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.7326/0003-4819-84-4-381

    authors: Moore ME,Berk SN

    更新日期:1976-04-01 00:00:00

  • Unrecognized adult salicylate intoxication.

    abstract::Adult salicylate intoxication has been considered to be easily recognized and assciated with low morbidity and mortality. In the present study of 73 consecutive adults hospitalized with salicylate intoxication, 27% of patients were undiagnosed for as long as 72 h after admission. The initial physical findings and labo...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-85-6-745

    authors: Anderson RJ,Potts DE,Gabow PA,Rumack BH,Schrier RW

    更新日期:1976-12-01 00:00:00

  • Triple-combination pharmacotherapy for medically ill smokers: a randomized trial.

    abstract:BACKGROUND:Smokers with medical illnesses are at particular risk for complications caused by tobacco. Clinical trial data on the effectiveness of triple-combination pharmacotherapy for tobacco dependence treatment in these high-risk smokers are not available. OBJECTIVE:To evaluate extended duration of a triple-medicat...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.7326/0003-4819-150-7-200904070-00004

    authors: Steinberg MB,Greenhaus S,Schmelzer AC,Bover MT,Foulds J,Hoover DR,Carson JL

    更新日期:2009-04-07 00:00:00

  • Primary pulmonary hypertension. A national prospective study.

    abstract::A national registry was begun in 1981 to collect data from 32 centers on patients diagnosed by uniform criteria as having primary pulmonary hypertension. Entered into the registry were 187 patients with a mean age (+/- SD) of 36 +/- 15 years (range, 1 to 81), and a female-to-male ratio of 1.7:1 overall. The mean inter...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-107-2-216

    authors: Rich S,Dantzker DR,Ayres SM,Bergofsky EH,Brundage BH,Detre KM,Fishman AP,Goldring RM,Groves BM,Koerner SK

    更新日期:1987-08-01 00:00:00

  • Cost-effectiveness of full medicare coverage of angiotensin-converting enzyme inhibitors for beneficiaries with diabetes.

    abstract:BACKGROUND:Angiotensin-converting enzyme (ACE) inhibitors slow renal disease progression and reduce cardiac morbidity and mortality in patients with diabetes. Patients' out-of-pocket costs pose a barrier to using this effective therapy. OBJECTIVE:To estimate the cost-effectiveness to Medicare of first-dollar coverage ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-143-2-200507190-00007

    authors: Rosen AB,Hamel MB,Weinstein MC,Cutler DM,Fendrick AM,Vijan S

    更新日期:2005-07-19 00:00:00

  • The book of job and the modern view of depression.

    abstract::The Biblical Book of Job is a wisdom book. Wisdom, in this context, refers to the intellectual discipline taught by the sages of ancient Isreael to provide professionals with a realistic approach to the problems of life. Chapter 30 of the Book of Job is a key-index of ideas that, if followed through the book, disclose...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-86-5-667

    authors: Kapusta MA,Frank S

    更新日期:1977-05-01 00:00:00

  • Low bone density is an etiologic factor for stress fractures in athletes.

    abstract:OBJECTIVE:To determine whether low bone density and other risk factors for osteoporosis are associated with stress fractures in athletes. DESIGN:Case-control study. SETTING:Institutional sports injury clinic with primary and secondary care. PARTICIPANTS:Twenty-five athletes (nineteen women) with scintigraphically co...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-113-10-754

    authors: Myburgh KH,Hutchins J,Fataar AB,Hough SF,Noakes TD

    更新日期:1990-11-15 00:00:00

  • Tracheal occlusion pressure: a simple index to monitor respiratory muscle fatigue during acute respiratory failure in patients with chronic obstructive pulmonary disease.

    abstract:STUDY OBJECTIVE:To assess respiratory muscle fatigue in acute respiratory failure in patients with chronic obstructive pulmonary disease and evaluate its influence on weaning patients from mechanical ventilation. DESIGN AND PATIENTS:We studied the time course of tracheal occlusion pressure (P0.1) and high-to-low ratio...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-108-6-800

    authors: Murciano D,Boczkowski J,Lecocguic Y,Emili JM,Pariente R,Aubier M

    更新日期:1988-06-01 00:00:00