Late development of systemic lupus erythematosus in patients with glomerular "fingerprint" deposits.

Abstract:

:Two patients presenting with nephrotic syndrome but without evidence of collagen vascular disease had organized glomerular immune deposits with a "fingerprint" pattern. This finding has been previously associated with lupus nephritis and, in our institution, has been seen in 6% of the biopsy specimens from patients with lupus nephritis. Clinical signs and symptoms of systemic lupus erythematosus in these two patients did not develop until 2 and 5 years later, respectively. The cases of these patients suggest that glomerular deposits with a fingerprint pattern may be a specific marker for lupus erythematosus even when overt clinical features of this disease are lacking. Patients with this finding on renal biopsy should have an extended follow-up for possible development of lupus erythematosus.

journal_name

Ann Intern Med

authors

Alpers CE,Hopper J Jr,Bernstein MJ,Biava CG

doi

10.7326/0003-4819-100-1-66

subject

Has Abstract

pub_date

1984-01-01 00:00:00

pages

66-8

issue

1

eissn

0003-4819

issn

1539-3704

journal_volume

100

pub_type

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