Evolving patterns of drug abuse.

Abstract:

:The sharp rise in drug abuse in the past decade has led to the development of new sources of information on drug-abuse trends. These include surveys, drug-related emergencies, drug-abuse treatment, hepatitis rates, and various types of law enforcement information. This paper summarizes data currently available for heroin, marijuana, cocaine, amphetamines, and barbiturates. Heroin use occurred in epidemic form in the late 1960s. Some cities, which had experienced a subsequent decline in heroin use, recently have reported an increase again. Marijuana use has increased steadily. The abuse of amphetamines and barbiturates appears to be growing. Trends on cocaine use are unclear. The development of ongoing, quantitative data-collection systems is beginning to clarify many of the issues regarding drug-use patterns and trends. With the possible exception of survey data, however, each indicator provides data only on selected segments of the drug-using population.

journal_name

Ann Intern Med

authors

Greene MH,Nightingale SL,DuPont RL

doi

10.7326/0003-4819-83-3-402

subject

Has Abstract

pub_date

1975-09-01 00:00:00

pages

402-11

issue

3

eissn

0003-4819

issn

1539-3704

journal_volume

83

pub_type

杂志文章
  • The vulnerable atherosclerotic plaque: scope of the literature.

    abstract::The scope of recent literature on the concept of "vulnerable plaque" was reviewed by examining 463 abstracts of primary and review articles identified through MEDLINE (2003 to April 2010). Proposed definition criteria of vulnerable plaque included active inflammation, a thin cap with a large lipid core, endothelial de...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-153-6-201009210-00272

    authors: Alsheikh-Ali AA,Kitsios GD,Balk EM,Lau J,Ip S

    更新日期:2010-09-21 00:00:00

  • Change in trans fatty acid content of fast-food purchases associated with New York City's restaurant regulation: a pre-post study.

    abstract:BACKGROUND:Dietary trans fat increases risk for coronary heart disease. In 2006, New York City (NYC) passed the first regulation in the United States restricting trans fat use in restaurants. OBJECTIVE:To assess the effect of the NYC regulation on the trans and saturated fat content of fast-food purchases. DESIGN:Cro...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-157-2-201207170-00004

    authors: Angell SY,Cobb LK,Curtis CJ,Konty KJ,Silver LD

    更新日期:2012-07-17 00:00:00

  • Physician reporting compared with medical-record review to identify adverse medical events.

    abstract:OBJECTIVE:To assess the effectiveness of housestaff physician reporting as a method for identifying adverse events on a medical service and to compare the physician reporting mechanism with a retrospective record review mechanism. SETTING:Medical service of an urban, university-affiliated teaching hospital. DESIGN:Co...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-119-5-199309010-00004

    authors: O'Neil AC,Petersen LA,Cook EF,Bates DW,Lee TH,Brennan TA

    更新日期:1993-09-01 00:00:00

  • Coronary angiography after thrombolytic therapy for acute myocardial infarction.

    abstract:PURPOSE:To review the status of emergency, urgent, routine, and selective angiography after intravenous thrombolytic therapy. DATA SOURCES:Relevant English-language articles published from January 1985 to July 1990 were identified through MEDLINE. STUDY SELECTION:For emergency angiography, four major randomized studi...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-114-10-877

    authors: Topol EJ,Holmes DR,Rogers WJ

    更新日期:1991-05-15 00:00:00

  • Autologous mesenchymal stem cells foster revascularization of ischemic limbs in systemic sclerosis: a case report.

    abstract:BACKGROUND:Mesenchymal stem cells can differentiate into endothelial cells and participate in angiogenesis in adults. In experimental models of acute myocardial infarction, mesenchymal stem cells led to the recovery of cardiac function through the formation of a new vascular network. OBJECTIVE:To describe treatment wi...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-153-10-201011160-00007

    authors: Guiducci S,Porta F,Saccardi R,Guidi S,Ibba-Manneschi L,Manetti M,Mazzanti B,Dal Pozzo S,Milia AF,Bellando-Randone S,Miniati I,Fiori G,Fontana R,Amanzi L,Braschi F,Bosi A,Matucci-Cerinic M

    更新日期:2010-11-16 00:00:00

  • Prevention of exacerbations of chronic obstructive pulmonary disease with tiotropium, a once-daily inhaled anticholinergic bronchodilator: a randomized trial.

    abstract:BACKGROUND:Patients with chronic obstructive pulmonary disease (COPD) frequently develop exacerbations, leading to major clinical and health resource use ramifications. OBJECTIVE:To prospectively evaluate the effectiveness of a long-acting inhaled anticholinergic bronchodilator, tiotropium, in reducing COPD exacerbati...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.7326/0003-4819-143-5-200509060-00007

    authors: Niewoehner DE,Rice K,Cote C,Paulson D,Cooper JA Jr,Korducki L,Cassino C,Kesten S

    更新日期:2005-09-06 00:00:00

  • Effects of HIV infection on the serologic manifestations and response to treatment of syphilis in intravenous drug users.

    abstract:OBJECTIVE:To describe the effects of human immunodeficiency virus (HIV) infection on the serologic manifestations and response to treatment of syphilis in intravenous drug users. DESIGN:Cohort study of intravenous drug users. SETTING:Medical clinic in a hospital-based methadone maintenance treatment program in New Yo...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-118-5-199303010-00005

    authors: Gourevitch MN,Selwyn PA,Davenny K,Buono D,Schoenbaum EE,Klein RS,Friedland GH

    更新日期:1993-03-01 00:00:00

  • Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial.

    abstract:BACKGROUND:Oral sildenafil and intravenous epoprostenol have independently been shown to be effective in patients with pulmonary arterial hypertension. OBJECTIVE:To investigate the effect of adding oral sildenafil to long-term intravenous epoprostenol in patients with pulmonary arterial hypertension. DESIGN:A 16-week...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.7326/0003-4819-149-8-200810210-00004

    authors: Simonneau G,Rubin LJ,Galiè N,Barst RJ,Fleming TR,Frost AE,Engel PJ,Kramer MR,Burgess G,Collings L,Cossons N,Sitbon O,Badesch DB,PACES Study Group.

    更新日期:2008-10-21 00:00:00

  • Contributions of obesity and weight loss to gallstone disease.

    abstract:OBJECTIVE:To examine the relation of obesity and weight loss to the formation of gallstones according to pertinent clinical and research issues. DATA SOURCES AND EXTRACTION:Original reports obtained through a MEDLINE search from 1966 to 1992 on gallstones plus obesity or reducing diets, supplemented by a manual search...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-119-10-199311150-00010

    authors: Everhart JE

    更新日期:1993-11-15 00:00:00

  • Transaminase elevations in patients receiving bovine or porcine heparin.

    abstract::Eighty-six patients who required heparin therapy were randomly assigned to receive bovine or porcine heparin. Abnormal concentrations of alanine transaminase and aspartate transaminase developed during treatment in 59.3% and 26.7% of patients, respectively. Patient characteristics that significantly influenced the dev...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.7326/0003-4819-100-5-646

    authors: Dukes GE Jr,Sanders SW,Russo J Jr,Swenson E,Burnakis TG,Saffle JR,Warden GD

    更新日期:1984-05-01 00:00:00

  • Assessing the generalizability of prognostic information.

    abstract::Physicians are often asked to make prognostic assessments but often worry that their assessments will prove inaccurate. Prognostic systems were developed to enhance the accuracy of such assessments. This paper describes an approach for evaluating prognostic systems based on the accuracy (calibration and discrimination...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-130-6-199903160-00016

    authors: Justice AC,Covinsky KE,Berlin JA

    更新日期:1999-03-16 00:00:00

  • In the clinic. Hypothyroidism.

    abstract::The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including PIER (Physicians' Information and Education Resource) and MKSAP (Medical Knowledge and Self Assessment Program). Annals of Internal Medicine editors develop In the Clinic f...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-151-11-200912010-01006

    authors: McDermott MT

    更新日期:2009-12-01 00:00:00

  • Variability in Pathologists' Interpretations of Individual Breast Biopsy Slides: A Population Perspective.

    abstract:BACKGROUND:The effect of physician diagnostic variability on accuracy at a population level depends on the prevalence of diagnoses. OBJECTIVE:To estimate how diagnostic variability affects accuracy from the perspective of a U.S. woman aged 50 to 59 years having a breast biopsy. DESIGN:Applied probability using Bayes'...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/M15-0964

    authors: Elmore JG,Nelson HD,Pepe MS,Longton GM,Tosteson AN,Geller B,Onega T,Carney PA,Jackson SL,Allison KH,Weaver DL

    更新日期:2016-05-17 00:00:00

  • Elevated serum levels of soluble Tac peptide in adult T-cell leukemia: correlation with clinical status during chemotherapy.

    abstract::Adult T-cell leukemia associated with human T-cell leukemia virus type I (HTLV-I) is characterized by a clonal expansion of a CD4-positive subset of T lymphocytes that constitutively express high numbers of interleukin-2 receptors and that frequently infiltrate the skin; osteolytic bone lesions, and hypercalcemia. Usi...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-109-4-274

    authors: Marcon L,Rubin LA,Kurman CC,Fritz ME,Longo DL,Uchiyama T,Edwards BK,Nelson DL

    更新日期:1988-08-15 00:00:00

  • Predicting Bleeding Risk to Guide Aspirin Use for the Primary Prevention of Cardiovascular Disease: A Cohort Study.

    abstract:Background:Many prognostic models for cardiovascular risk can be used to estimate aspirin's absolute benefits, but few bleeding risk models are available to estimate its likely harms. Objective:To develop prognostic bleeding risk models among persons in whom aspirin might be considered for the primary prevention of ca...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/M18-2808

    authors: Selak V,Jackson R,Poppe K,Wu B,Harwood M,Grey C,Pylypchuk R,Mehta S,Kerr A,Wells S

    更新日期:2019-03-19 00:00:00

  • Activation and regulation of human immune responses: implications in normal and disease states.

    abstract::A model of activation, proliferation, and differentiation of human lymphocyte responses is described, and the complex immunoregulatory modulation of this system discussed with regard to normal immune function and the aberrancies expressed in diseases characterized by abnormalities of immune function. Recent advances i...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-99-1-61

    authors: Fauci AS,Lane HC,Volkman DJ

    更新日期:1983-07-01 00:00:00

  • Care of the Patient Using Cannabis.

    abstract::The past 2 decades have seen a revolution in legal access to cannabis, driven largely by activists and business interests. As a result, the population of cannabis users nationwide-especially daily users-has grown significantly. An estimated 4.5-7 million persons in the United States now meet criteria for cannabis use ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/AITC202011030

    authors: Williams AR,Hill KP

    更新日期:2020-11-03 00:00:00

  • Direct binding studies of adrenergic receptors: biochemical, physiologic, and clinical implications.

    abstract::Recently developed radioligand binding techniques permit direct investigation of the alpha- and beta-adrenergic receptors for catecholamines in a wide variety of tissues. These techniques allow the receptors to be quantitated, characterized, and studied under varying conditions of physiologic and pathophysiologic inte...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-91-3-450

    authors: Lefkowitz RJ

    更新日期:1979-09-01 00:00:00

  • Growth hormone replacement in healthy older men improves body composition but not functional ability.

    abstract:OBJECTIVE:To determine whether growth hormone replacement in older men improves functional ability. DESIGN:Randomized, controlled, double-blind trial. SETTING:General community. PATIENTS:52 healthy men older than 69 years of age with well-preserved functional ability but low baseline insulin-like growth factor 1 lev...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.7326/0003-4819-124-8-199604150-00002

    authors: Papadakis MA,Grady D,Black D,Tierney MJ,Gooding GA,Schambelan M,Grunfeld C

    更新日期:1996-04-15 00:00:00

  • Improvements in diabetes processes of care and intermediate outcomes: United States, 1988-2002.

    abstract:BACKGROUND:Progress of diabetes care is a subject of public health concern. OBJECTIVE:To assess changes in quality of diabetes care in the United States by using standardized measures. DESIGN:National population-based, serial cross-sectional surveys. SETTING:National Health and Nutrition Examination Survey (1988-199...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-144-7-200604040-00005

    authors: Saaddine JB,Cadwell B,Gregg EW,Engelgau MM,Vinicor F,Imperatore G,Narayan KM

    更新日期:2006-04-04 00:00:00

  • Effect of treatment of Helicobacter pylori infection on the long-term recurrence of gastric or duodenal ulcer. A randomized, controlled study.

    abstract:OBJECTIVE:To determine the effect of treating Helicobacter pylori infection on the recurrence of gastric and duodenal ulcer disease. DESIGN:Follow-up of up to 2 years in patients with healed ulcers who had participated in randomized, controlled trials. SETTING:A Veterans Affairs hospital. PARTICIPANTS:A total of 109...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.7326/0003-4819-116-9-705

    authors: Graham DY,Lew GM,Klein PD,Evans DG,Evans DJ Jr,Saeed ZA,Malaty HM

    更新日期:1992-05-01 00:00:00

  • Spondyloarthropathy associated with hidradenitis suppurative and acne conglobata.

    abstract::We evaluated 10 patients with hidradenitis suppurative or acne conglobata who developed arthritis. In contrast to patients with acne fulminans and arthritis, all our subjects were adults over 22 years of age; nine were black; and four were women. Nine patients had episodic inflammatory oligoarthritis affecting mainly ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-97-4-520

    authors: Rosner IA,Richter DE,Huettner TL,Kuffner GH,Wisnieski JJ,Burg CG

    更新日期:1982-10-01 00:00:00

  • Evaluation of Hospital Performance Using the Excess Days in Acute Care Measure in the Hospital Readmissions Reduction Program.

    abstract::The Hospital Readmissions Reduction Program (HRRP) has penalized hospitals with higher 30-day readmission rates more than $3 billion to date. Clinicians and policy experts have raised concerns that the 30-day readmission measure used in this program provides an incomplete picture of performance because it does not cap...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/M20-3486

    authors: Wadhera RK,Joynt Maddox KE,Desai NR,Landon BE,Md MV,Gilstrap LG,Shen C,Yeh RW

    更新日期:2021-01-01 00:00:00

  • In the clinic. Sickle cell disease.

    abstract::This issue provides a clinical overview of sickle cell disease focusing on prevention, diagnosis, treatment, practice improvement, and patient information. Readers can complete the accompanying CME quiz for 1.5 credits. Only ACP members and individual subscribers can access the electronic features of In the Clinic. No...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-155-5-201109060-01003

    authors: Steinberg MH

    更新日期:2011-09-06 00:00:00

  • Deficiency of fat-soluble vitamins in treated patients with pancreatic insufficiency.

    abstract::Deficiency of fat-soluble vitamins (A,D,E, and K) was evaluated in 15 patients with exocrine pancreatic insufficiency secondary to chronic alcoholic pancreatitis. Mild to moderate steatorrhea was present in all patients despite oral pancreatic enzyme therapy for 27 +/- 4 months (mean +/- SE). Deficiency of a single fa...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-97-4-549

    authors: Dutta SK,Bustin MP,Russell RM,Costa BS

    更新日期:1982-10-01 00:00:00

  • Sideroblastic anemia as a preleukemic event in patients treated for Hodgkin's disease.

    abstract::Sideroblastic anemia after treatment for Hogdkin's disease was seen in two patients 3 years after completion of radiation therapy and chemotherapy. This was followed in both by the development of myelomonoblastic leukemia. No evidence of recurrent Hodgkin's disease was present in either patient. Our observation sugges...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-92-5-625

    authors: Kitahara M,Cosgriff TM,Eyre HJ

    更新日期:1980-05-01 00:00:00

  • Herniated lumbar intervertebral disk.

    abstract::Low back pain is common, but a herniated intervertebral disk is the cause in only a small percentage of cases. Most symptomatic disk herniations result in clinical manifestations (pain, reflex loss, muscle weakness) that resolve with conservative therapy, and only 5% to 10% of patients require surgery. Sciatica is usu...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-112-8-598

    authors: Deyo RA,Loeser JD,Bigos SJ

    更新日期:1990-04-15 00:00:00

  • Transfusion-acquired human immunodeficiency virus infection among immunocompromised persons.

    abstract::Transmission of the human immunodeficiency virus (HIV) was studied in a group of patients with cancer who received transfusion of blood components harvested from a single, asymptomatic, seropositive donor. Of ten living recipients, nine had antibodies to the virus in fresh or cryopreserved sera at a median of 384 days...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-105-4-519

    authors: Anderson KC,Gorgone BC,Marlink RG,Ferriani R,Essex ME,Benz PM,Groopman JE

    更新日期:1986-10-01 00:00:00

  • Travel-Associated Zika Virus Disease Acquired in the Americas Through February 2016: A GeoSentinel Analysis.

    abstract:Background:Zika virus has spread rapidly in the Americas and has been imported into many nonendemic countries by travelers. Objective:To describe clinical manifestations and epidemiology of Zika virus disease in travelers exposed in the Americas. Design:Descriptive, using GeoSentinel records. Setting:63 travel and t...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/M16-1842

    authors: Hamer DH,Barbre KA,Chen LH,Grobusch MP,Schlagenhauf P,Goorhuis A,van Genderen PJ,Molina I,Asgeirsson H,Kozarsky PE,Caumes E,Hagmann SH,Mockenhaupt FP,Eperon G,Barnett ED,Bottieau E,Boggild AK,Gautret P,Hynes NA,Kuhn

    更新日期:2017-01-17 00:00:00

  • Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society.

    abstract:DESCRIPTION:This guideline is an official statement of the American College of Physicians (ACP), American College of Chest Physicians (ACCP), American Thoracic Society (ATS), and European Respiratory Society (ERS). It represents an update of the 2007 ACP clinical practice guideline on diagnosis and management of stable...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,实务指引

    doi:10.7326/0003-4819-155-3-201108020-00008

    authors: Qaseem A,Wilt TJ,Weinberger SE,Hanania NA,Criner G,van der Molen T,Marciniuk DD,Denberg T,Schünemann H,Wedzicha W,MacDonald R,Shekelle P,American College of Physicians.,American College of Chest Physicians.,American Thoracic

    更新日期:2011-08-02 00:00:00