Direct binding studies of adrenergic receptors: biochemical, physiologic, and clinical implications.

Abstract:

:Recently developed radioligand binding techniques permit direct investigation of the alpha- and beta-adrenergic receptors for catecholamines in a wide variety of tissues. These techniques allow the receptors to be quantitated, characterized, and studied under varying conditions of physiologic and pathophysiologic interest. They are providing fresh insights into the mechanisms by which endogenous catecholamines and other hormones regulate the properties of the adrenergic receptors and, in turn, control tissue sensitivity to catecholamine action.

journal_name

Ann Intern Med

authors

Lefkowitz RJ

doi

10.7326/0003-4819-91-3-450

subject

Has Abstract

pub_date

1979-09-01 00:00:00

pages

450-8

issue

3

eissn

0003-4819

issn

1539-3704

journal_volume

91

pub_type

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    authors: Nissenson AR,Baraff LJ,Fine RN,Knutson DW

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    更新日期:1989-12-01 00:00:00

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    pub_type: 杂志文章,meta分析,评审

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