Comparison of chemical composition of peritoneal fluid and serum: a method for monitoring dialysis patients and a tool for assessing binding to serum proteins in vivo.

Abstract:

:It is hypothesized that peritoneal fluid might be used as an alternative vehicle for monitoring the clinical chemistry of patients on peritoneal dialyses and save these patients the venesection and resultant blood loss. Peritoneal fluid was obtained before 47.2% of 106 dialysis treatments and compared with simultaneous serum samples. Very close correlation was noted for phosphorus, uric acid, blood urea nitrogen, creatinine, potassium, bicarbonate, and sodium (r greater than 0.82, p less than 10(-6)), and we conclude that peritoneal fluid may be useful for monitoring these chemistries. The peritoneal fluid concentrations of calcium and albumin were consistently 20% and 43% lower than the corresponding serum values. Because the peritoneal fluid is in equilibrium with the serum, it could also be used to measure protein binding of low molecular-weight substances in vivo that cross the peritoneal membrane. The results presented here fail to support the suggestion that urate is bound to serum proteins in vivo.

journal_name

Ann Intern Med

authors

Kelton JG,Ulan R,Stiller C,Holmes E

doi

10.7326/0003-4819-89-1-67

subject

Has Abstract

pub_date

1978-07-01 00:00:00

pages

67-70

issue

1

eissn

0003-4819

issn

1539-3704

journal_volume

89

pub_type

杂志文章
  • The burden of health care costs for patients with dementia in the last 5 years of life.

    abstract:BACKGROUND:Common diseases, particularly dementia, have large social costs for the U.S. population. However, less is known about the end-of-life costs of specific diseases and the associated financial risk for individual households. OBJECTIVE:To examine social costs and financial risks faced by Medicare beneficiaries ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/M15-0381

    authors: Kelley AS,McGarry K,Gorges R,Skinner JS

    更新日期:2015-11-17 00:00:00

  • A professional response to demands for accountability: practical recommendations regarding ethical aspects of patient care. Working Group on Accountability.

    abstract::Forceful new demands for accountability in medicine are arising from many interested parties. To maintain professional standards, physicians need to establish which demands are desirable and which are not. We adopt a model of stratified accountability that includes three major components: the accountable parties, the ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-124-2-199601150-00008

    authors: Emanuel LL

    更新日期:1996-01-15 00:00:00

  • Asymptomatic coronary artery disease: angiography in diabetic patients before renal transplantation. Relation of findings to postoperative survival.

    abstract::Twenty-one juvenile-onset diabetic patients with azotemic nephropathy underwent coronary angiography and left ventriculography before renal transplantation or chronic hemodialysis. Two-year survival of 12 patients with no coronary artery disease (group A) was 88% compared to 22% for nine patients with coronary artery ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-88-3-346

    authors: Weinrauch LA,D'elia JA,Healy RW,Gleason RE,Takacs FJ,Libertino JA,Leland OS

    更新日期:1978-03-01 00:00:00

  • Diuretics, beta-blockers, and the risk for sudden cardiac death in hypertensive patients.

    abstract:OBJECTIVE:To determine whether the use of non-potassium-sparing diuretics and beta-blockers is associated with an excess risk for sudden cardiac death in hypertensive patients. DESIGN:Case-control study. SETTING:Rotterdam, the Netherlands. PATIENTS:257 case-patients who had died suddenly while receiving drug therapy...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-123-7-199510010-00001

    authors: Hoes AW,Grobbee DE,Lubsen J,Man in 't Veld AJ,van der Does E,Hofman A

    更新日期:1995-10-01 00:00:00

  • Bilateral massive adrenal hemorrhage: early recognition and treatment.

    abstract:PURPOSE:To develop a clinical perspective on bilateral massive adrenal hemorrhage and an algorithm for its diagnosis and treatment. DATA IDENTIFICATION:Case reports were identified through a computer search using MEDLIN (1976 to 1987), and from bibliographies in review articles (up to 1978). STUDY SELECTION:Twelve re...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-110-3-227

    authors: Rao RH,Vagnucci AH,Amico JA

    更新日期:1989-02-01 00:00:00

  • Physician practices in the prevention of venous thromboembolism.

    abstract:OBJECTIVE:To determine the rate of use of prophylaxis for venous thromboembolism in high-risk hospital patients. DESIGN:A retrospective medical record review. SETTING:A community-wide study in 16 short-stay hospitals in central Massachusetts. PATIENTS:A total of 2017 patients with multiple risk factors for venous th...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-591

    authors: Anderson FA Jr,Wheeler HB,Goldberg RJ,Hosmer DW,Forcier A,Patwardhan NA

    更新日期:1991-10-15 00:00:00

  • Should This Patient Receive Aspirin?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center.

    abstract::Aspirin exerts antiplatelet effects through irreversible inhibition of cyclooxygenase-1, whereas its anticancer effects may be due to inhibition of cyclooxygenase-2 and other pathways. In 2009, the U.S. Preventive Services Task Force endorsed aspirin for primary prevention of cardiovascular disease. However, aspirin's...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/M17-2162

    authors: Burns RB,Graham K,Sawhney MS,Reynolds EE

    更新日期:2017-12-05 00:00:00

  • Redesigning residency education in internal medicine: a position paper from the Association of Program Directors in Internal Medicine.

    abstract::There has been considerable change in the practice of internal medicine in the past quarter century, including the rise of specialization, increasing time pressure, the hospitalist movement, and the rapidly changing responsibilities of internists in inpatient and outpatient settings. Training programs have not adequat...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-144-12-200606200-00010

    authors: Association of Program Directors in Internal Medicine.,Fitzgibbons JP,Bordley DR,Berkowitz LR,Miller BW,Henderson MC

    更新日期:2006-06-20 00:00:00

  • Leukotriene-receptor antagonists versus placebo in the treatment of asthma in adults and adolescents: a systematic review and meta-analysis.

    abstract:BACKGROUND:Leukotriene-receptor antagonists (LTRAs) are recommended as an alternative treatment in patients with mild asthma, but their effect compared with placebo is unclear. PURPOSE:To determine the benefits and harms of LTRAs as monotherapy or in combination with inhaled corticosteroids compared with placebo in ad...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.7326/M15-1059

    authors: Miligkos M,Bannuru RR,Alkofide H,Kher SR,Schmid CH,Balk EM

    更新日期:2015-11-17 00:00:00

  • Prolonged survival in chronic myelogenous leukemia after cytogenetic response to interferon-alpha therapy. The Leukemia Service.

    abstract:OBJECTIVE:To determine whether a cytogenetic response after interferon-alpha therapy in patients with chronic myelogenous leukemia is independently associated with improved survival. DESIGN:Retrospective analysis. PATIENTS:274 patients with a diagnosis of Philadelphia chromosome-positive chronic myelogenous leukemia ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-122-4-199502150-00003

    authors: Kantarjian HM,Smith TL,O'Brien S,Beran M,Pierce S,Talpaz M

    更新日期:1995-02-15 00:00:00

  • Management of suspected deep venous thrombosis in outpatients by using clinical assessment and D-dimer testing.

    abstract:BACKGROUND:When deep venous thrombosis is suspected, objective testing is required to confirm or refute the diagnosis. OBJECTIVE:To determine whether the combination of a low clinical suspicion and a normal D -dimer result rules out deep venous thrombosis. DESIGN:Prospective cohort study. SETTING:Three tertiary care...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-135-2-200107170-00011

    authors: Kearon C,Ginsberg JS,Douketis J,Crowther M,Brill-Edwards P,Weitz JI,Hirsh J

    更新日期:2001-07-17 00:00:00

  • Documentation of contraception and pregnancy when prescribing potentially teratogenic medications for reproductive-age women.

    abstract:BACKGROUND:Certain medications are identified by the U.S. Food and Drug Administration (FDA) as class D or X because they increase the risk for birth defects if used during pregnancy. OBJECTIVE:To assess pregnancy rates and the frequency of contraceptive counseling documented with prescriptions for class D or X drugs ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-147-6-200709180-00006

    authors: Schwarz EB,Postlethwaite DA,Hung YY,Armstrong MA

    更新日期:2007-09-18 00:00:00

  • Daily aspirin for primary prevention increased risk for major GI bleeding in healthy older adults.

    abstract:SOURCE CITATION:Mahady SE, Margolis KL, Chan A, et al. Major GI bleeding in older persons using aspirin: incidence and risk factors in the ASPREE randomised controlled trial. Gut. 2020. [Epub ahead of print.] 32747412. ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/ACPJ202101190-004

    authors: Hirsch C

    更新日期:2021-01-01 00:00:00

  • Primary cardiac amyloidosis: an angiocardiographic clue to early diagnosis.

    abstract::Restrictive cardiomyopathy produced by primary cardiac amyloidosis may have a clinical syndrome identical to noncalcific constrictive pericarditis. We report two patients with amyloidosis and restrictive physiology who had enlarged papillary muscles shown on left ventricular angiocardiogram. Rapid volume expansion wit...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-98-2-177

    authors: Maule WF,Martin RH

    更新日期:1983-02-01 00:00:00

  • Sudden cardiac death: epidemiology, transient risk, and intervention assessment.

    abstract:PURPOSE:To integrate information from the various disciplines that contribute to the understanding of the cause and prevention of sudden cardiac death: identification of new approaches from applied clinical epidemiology; identification and control of transient risk factors; and evaluation of the results of intervention...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

    doi:10.7326/0003-4819-119-12-199312150-00006

    authors: Myerburg RJ,Kessler KM,Castellanos A

    更新日期:1993-12-15 00:00:00

  • Update on the methods of the U.S. Preventive Services Task Force: insufficient evidence.

    abstract::The U.S. Preventive Services Task Force (USPSTF) seeks to provide reliable and accurate evidence-based recommendations to primary care clinicians. However, clinicians indicate frustration with the lack of guidance provided by the USPSTF when the evidence is insufficient to make a recommendation. This article describes...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-150-3-200902030-00010

    authors: Petitti DB,Teutsch SM,Barton MB,Sawaya GF,Ockene JK,DeWitt T,U.S. Preventive Services Task Force.

    更新日期:2009-02-03 00:00:00

  • Reduction of doxorubicin cardiotoxicity by prolonged continuous intravenous infusion.

    abstract::Doxorubicin (Adriamycin) was administered by continuous infusion to reduce peak plasma levels and thus lessen cardiac toxicity. Cardiotoxicity was monitored by noninvasive methods, and endomyocardial biopsy specimens were studied by electronmicroscopy. Cardiotoxicity was compared in 21 patients receiving doxorubicin i...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-96-2-133

    authors: Legha SS,Benjamin RS,Mackay B,Ewer M,Wallace S,Valdivieso M,Rasmussen SL,Blumenschein GR,Freireich EJ

    更新日期:1982-02-01 00:00:00

  • Non-drug treatment of hypertension.

    abstract::As more people with mild hypertension are treated, non-drug therapies should be used more frequently and effectively. These therapies include weight reduction; sodium restriction; potassium, calcium, and magnesium supplementation; other dietary changes; exercise; relaxation; and moderation of alcohol use. Such therapi...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,评审

    doi:10.7326/0003-4819-102-3-359

    authors: Kaplan NM

    更新日期:1985-03-01 00:00:00

  • Remdesivir for Adults With COVID-19 : A Living Systematic Review for an American College of Physicians Practice Points.

    abstract:BACKGROUND:Few treatments exist for coronavirus disease 2019 (COVID-19). PURPOSE:To evaluate the effectiveness and harms of remdesivir for COVID-19. DATA SOURCES:Several databases, tables of contents of journals, and U.S. Food and Drug Administration and company websites were searched from 1 January through 31 August...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/M20-5752

    authors: Wilt TJ,Kaka AS,MacDonald R,Greer N,Obley A,Duan-Porter W

    更新日期:2020-10-05 00:00:00

  • Sedentary time and its association with risk for disease incidence, mortality, and hospitalization in adults: a systematic review and meta-analysis.

    abstract:BACKGROUND:The magnitude, consistency, and manner of association between sedentary time and outcomes independent of physical activity remain unclear. PURPOSE:To quantify the association between sedentary time and hospitalizations, all-cause mortality, cardiovascular disease, diabetes, and cancer in adults independent ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.7326/M14-1651

    authors: Biswas A,Oh PI,Faulkner GE,Bajaj RR,Silver MA,Mitchell MS,Alter DA

    更新日期:2015-01-20 00:00:00

  • The case for treating tobacco dependence as a chronic disease.

    abstract::Smoking remains the leading cause of preventable death in the United States, yet it is still regarded by many as merely a bad habit. Most smokers want to quit but find it difficult. Behavioral counseling and pharmacotherapies are available, safe, and effective in the treatment of tobacco dependence. Nicotine replaceme...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-148-7-200804010-00012

    authors: Steinberg MB,Schmelzer AC,Richardson DL,Foulds J

    更新日期:2008-04-01 00:00:00

  • Incompetent patients with limited care in the absence of family consent. A study of socioeconomic and clinical variables.

    abstract::To understand the factors that distinguish terminally ill, incompetent patients who are given do-not-resuscitate status by physicians against the wishes of the patient's family, I reviewed the charts of 20 such patients (cases) seen in consultation by the ethics committee at the Massachusetts General Hospital over 10 ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-109-10-819

    authors: Brennan TA

    更新日期:1988-11-15 00:00:00

  • Better access to information about clinical trials.

    abstract::Access to information about clinical trials is important to researchers, health care professionals, and patients. Many have argued for the establishment of clinical trials registries, citing their substantial benefits. Although some registries do exist, it has been difficult to create comprehensive, easily accessible ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-133-8-200010170-00013

    authors: McCray AT

    更新日期:2000-10-17 00:00:00

  • Prevalence of neutropenia in the U.S. population: age, sex, smoking status, and ethnic differences.

    abstract:BACKGROUND:Benign reductions in neutrophil counts may be more common at certain ages and in certain ethnic groups and may be affected by sex and smoking status. OBJECTIVE:To determine differences in neutrophil counts in the U.S. population according to ethnicity, age, sex, and smoking status. DESIGN:Population-based,...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-146-7-200704030-00004

    authors: Hsieh MM,Everhart JE,Byrd-Holt DD,Tisdale JF,Rodgers GP

    更新日期:2007-04-03 00:00:00

  • Reduced cardiotoxicity of doxorubicin delivered on a weekly schedule. Assessment by endomyocardial biopsy.

    abstract::Endomyocardial biopsy was done 119 times in 98 patients receiving doxorubicin therapy once every 3 weeks and 41 times in 27 patients receiving doxorubicin therapy weekly. Factors contributing to the degree of anthracycline-induced endomyocardial injury were evaluated. Neither age, sex, type of malignancy, concomitant ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-99-6-745

    authors: Torti FM,Bristow MR,Howes AE,Aston D,Stockdale FE,Carter SK,Kohler M,Brown BW Jr,Billingham ME

    更新日期:1983-12-01 00:00:00

  • The demise of primary care: a diatribe from the trenches.

    abstract::Medical school graduates are avoiding primary care. The very aspects that once attracted students have been subverted. The breadth of practice that was once appealing has become the breadth of heavy-handed scrutiny, as politicians and business leaders have demanded quality--simplistically defined as dogmatic adherence...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-150-10-200905190-00011

    authors: Norenberg DD

    更新日期:2009-05-19 00:00:00

  • The safety of treadmill exercise stress testing in patients with abdominal aortic aneurysms.

    abstract:BACKGROUND:Exercise stress testing in patients with abdominal aortic aneurysms may cause enlargement or rupture of aneurysms. OBJECTIVE:To evaluate the safety of treadmill exercise stress testing in patients with abdominal aortic aneurysms. DESIGN:Retrospective descriptive study. SETTING:Tertiary care center. PATIE...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-129-8-199810150-00008

    authors: Best PJ,Tajik AJ,Gibbons RJ,Pellikka PA

    更新日期:1998-10-15 00:00:00

  • Diagnostic utility of ultrasonography of leg veins in patients suspected of having pulmonary embolism.

    abstract:BACKGROUND:The standard diagnostic approach in patients suspected of having pulmonary embolism starts with perfusion-ventilation lung scanning. If the resulting scan is not diagnostic, pulmonary angiography should be done. The use of tests for deep venous thrombosis has been advocated as an adjunct to establishing the ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-126-10-199705150-00005

    authors: Turkstra F,Kuijer PM,van Beek EJ,Brandjes DP,ten Cate JW,Büller HR

    更新日期:1997-05-15 00:00:00

  • Improving patient care. My right knee.

    abstract::Despite some impressive recent gains, improving the glaring deficiencies in health care quality is proving to be very hard. Improvement is local, rather than system-wide, and is sustained with difficulty, rather than becoming an intrinsic feature of care. My right knee will probably need to be replaced soon. This has ...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-142-2-200501180-00011

    authors: Berwick DM

    更新日期:2005-01-18 00:00:00

  • Levothyroxine and potassium iodide are both effective in treating benign solitary solid cold nodules of the thyroid.

    abstract:OBJECTIVE:To determine the effectiveness of levothyroxine and potassium iodide in treating patients with benign solitary cold thyroid nodules. DESIGN:Randomized controlled study. SETTING:Outpatient clinic at a university hospital. PATIENTS:80 patients with solitary solid cold thyroid nodules found to be benign at cy...

    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.7326/0003-4819-122-1-199501010-00001

    authors: La Rosa GL,Lupo L,Giuffrida D,Gullo D,Vigneri R,Belfiore A

    更新日期:1995-01-01 00:00:00