Improving patient care. My right knee.

abstract：STUDY OBJECTIVE:To evaluate the efficacy of cisplatin-based combination chemotherapy in patients with advanced ovarian germ-cell tumors. DESIGN:Nonrandom prospective trial with endpoints of tumor response, results of repeat surgical exploration, progression-free interval, and survival. SETTING:Cooperative university-...

journal_title：Annals of internal medicine

authors： Williams SD,Blessing JA,Moore DH,Homesley HD,Adcock L

更新日期：1989-07-01 00:00:00

abstract：:Important historical changes have occurred both in the content of the periodic health examination and in the legitimacy with which this examination has been viewed. These changes reflect fundamental shifts in the objectives of the examination and in the concerns of its advocates, the most prominent of whom have been p...

journal_title：Annals of internal medicine

authors： Han PK

更新日期：1997-11-15 00:00:00

abstract：Background:Acute pancreatitis (AP) varies in severity, prompting development of systems aimed at predicting prognosis to help guide therapy. Although several prediction approaches are available, their test characteristics and clinical utility are not completely understood. Purpose:To evaluate the test characteristics ...

journal_title：Annals of internal medicine

authors： Di MY,Liu H,Yang ZY,Bonis PA,Tang JL,Lau J

更新日期：2016-10-04 00:00:00

abstract：:A group of 44 homosexual patients with immune thrombocytopenia and serologic evidence of infection with the human immunodeficiency virus (HIV) was observed for a total of 844 person-months. The risk of developing the acquired immunodeficiency syndrome (AIDS), an actuarial incidence of 36.5% in 37 months, was no differ...

journal_title：Annals of internal medicine

authors： Holzman RS,Walsh CM,Karpatkin S

更新日期：1987-03-01 00:00:00

abstract：:Medical professional codes have long prohibited physician involvement in assisting a patient's suicide. However, despite ethical and legal prohibitions, calls for the liberalization of this ban have grown in recent years. The medical profession should articulate its views on the arguments for and against changes in pu...

journal_title：Annals of internal medicine

authors： Snyder L,Sulmasy DP,Ethics and Human Rights Committee, American College of Physicians-American Society of Internal Medicine.

更新日期：2001-08-07 00:00:00

abstract：BACKGROUND:Primary aldosteronism is a common cause of treatment-resistant hypertension. However, evidence from local health systems suggests low rates of testing for primary aldosteronism. OBJECTIVE:To evaluate testing rates for primary aldosteronism and evidence-based hypertension management in patients with treatmen...

journal_title：Annals of internal medicine

authors： Cohen JB,Cohen DL,Herman DS,Leppert JT,Byrd JB,Bhalla V

更新日期：2020-12-29 00:00:00

abstract：:These supplemental recommendations provide guidelines for a monovalent influenza A(H1N1) vaccine for protection against a newly emerged variant of influenza that has recently caused outbreaks among children and young adults in Asia. Guidance is provided for the use of this monovalent vaccine, which contains 15 microgr...

journal_title：Annals of internal medicine

authors：

更新日期：1986-11-01 00:00:00

abstract：:The relation of menopause to cardiovascular disease incidence was examined in women less than 55 years old from the cohort of 2873 women in the initial Framingham examination. Although the number of person-years of experience during the 20 years of observation was nearly the same for premenopausal and postmenopausal s...

journal_title：Annals of internal medicine

authors： Kannel WB,Hjortland MC,McNamara PM,Gordon T

更新日期：1976-10-01 00:00:00

abstract：BACKGROUND:Medical students may be at high risk for occupational exposures to blood. OBJECTIVE:To measure the frequency of medical students' exposure to infectious body substances, to identify factors that affect the probability of such exposure, and to suggest targets for the prevention of such exposure. DESIGN:Revi...

journal_title：Annals of internal medicine

authors： Osborn EH,Papadakis MA,Gerberding JL

更新日期：1999-01-05 00:00:00

abstract：:With the renewed interest in esophageal motility disorders, diffuse esophageal spasm is being diagnosed more frequently. In many clinical settings, however, the term is used as a synonym for noncardiac chest pain. Our review of the literature and broad clinical experience in studying the motility patterns of healthy s...

journal_title：Annals of internal medicine

authors： Richter JE,Castell DO

更新日期：1984-02-01 00:00:00

abstract：OBJECTIVE:To determine the relations among esophageal dysfunction, gastroesophageal reflux, and lung involvement in patients with systemic sclerosis. DESIGN:Retrospective review of esophageal motility, esophageal pH, and pulmonary function data. SETTING:University hospital outpatient clinic and community. PATIENTS:3...

journal_title：Annals of internal medicine

authors： Troshinsky MB,Kane GC,Varga J,Cater JR,Fish JE,Jimenez SA,Castell DO

更新日期：1994-07-01 00:00:00

abstract：:The insulin-like growth factor (IGF) family of peptides, binding proteins, and receptors are ubiquitous and important for normal human growth and development. Modern techniques including specific radioimmunoassays, radioreceptor assays and recombinant DNA technology have improved our understanding of the role of IGFs ...

journal_title：Annals of internal medicine

authors： LeRoith D,Clemmons D,Nissley P,Rechler MM

更新日期：1992-05-15 00:00:00

abstract：:Aspirin exerts antiplatelet effects through irreversible inhibition of cyclooxygenase-1, whereas its anticancer effects may be due to inhibition of cyclooxygenase-2 and other pathways. In 2009, the U.S. Preventive Services Task Force endorsed aspirin for primary prevention of cardiovascular disease. However, aspirin's...

journal_title：Annals of internal medicine

authors： Burns RB,Graham K,Sawhney MS,Reynolds EE

更新日期：2017-12-05 00:00:00

abstract：:Three patients had diverticulitis and extraintestinal manifestations of arthritis and pyoderma gangrenosum. In each, a mistaken diagnosis of idiopathic inflammatory bowel disease was first made because of extraintestinal complaints associated with the gastrointestinal symptoms of diverticular disease. The joint and sk...

journal_title：Annals of internal medicine

authors： Klein S,Mayer L,Present DH,Youner KD,Cerulli MA,Sachar DB

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:Hospice providers contend that enrollment reduces the cost of the Medicare programs, but estimates of effects are dated, methodologically limited, and focused on persons with cancer. OBJECTIVE:To estimate the effects of hospice care on Medicare program payments during the last year of life from 1996 to 1999...

journal_title：Annals of internal medicine

authors： Campbell DE,Lynn J,Louis TA,Shugarman LR

更新日期：2004-02-17 00:00:00

abstract：:We surveyed the faculty, fellows, and residents of a department of medicine to determine the relative importance of each of eight personal characteristics evaluated during the interview of house staff candidates. A booklet containing all possible pairings of the eight characteristics was distributed to 219 participant...

journal_title：Annals of internal medicine

authors： Greganti MA,McGaghie WC,Finn WF

更新日期：1982-07-01 00:00:00

abstract：:During 1973 and 1974, we looked for cases of Colorado tick fever throughout Colorado; 228 cases were identified. Although 90% of the patients reported exposure to ticks before illness, only 52% were aware of an actual tick bite. Typical symptoms of fever, myalgia, and headache were common, but gastrointestinal symptom...

journal_title：Annals of internal medicine

authors： Goodpasture HC,Poland JD,Francy DB,Bowen GS,Horn KA

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND:Progress of diabetes care is a subject of public health concern. OBJECTIVE:To assess changes in quality of diabetes care in the United States by using standardized measures. DESIGN:National population-based, serial cross-sectional surveys. SETTING:National Health and Nutrition Examination Survey (1988-199...

journal_title：Annals of internal medicine

authors： Saaddine JB,Cadwell B,Gregg EW,Engelgau MM,Vinicor F,Imperatore G,Narayan KM

更新日期：2006-04-04 00:00:00

abstract：:Meta-analysis is the process of combining study results that can be used to draw conclusions about therapeutic effectiveness or to plan new studies. We review important design and statistical issues of this process. The design issues include protocol development, objectives, literature search, publication bias, measur...

journal_title：Annals of internal medicine

authors： L'Abbé KA,Detsky AS,O'Rourke K

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:The appropriate roles for several diagnostic tests for coronary disease are uncertain. OBJECTIVE:To evaluate the cost-effectiveness of alternative approaches to diagnosis of coronary disease. DESIGN:Meta-analysis of the accuracy of alternative diagnostic tests plus decision analysis to assess the health ou...

journal_title：Annals of internal medicine

authors： Garber AM,Solomon NA

更新日期：1999-05-04 00:00:00

abstract：:Tetanus is an expected complication when disasters strike in developing countries, where tetanus immunization coverage is often low or nonexistent. Collapsing structures and swirling debris inflict numerous crush injuries, fractures, and serious wounds. Clostridium tetani infects wounds contaminated with dirt, feces, ...

journal_title：Annals of internal medicine

authors： Afshar M,Raju M,Ansell D,Bleck TP

更新日期：2011-03-01 00:00:00

abstract：:Elevated serum digoxin concentrations and clinical toxicity have been reported in patients receiving quinidine. The present study was undertaken to ascertain whether a similar interaction occurs between quinidine and another cardiac glycoside, digitoxin, and if so to evaluate the pharmacokinetic basis in five healthy ...

journal_title：Annals of internal medicine

authors： Garty M,Sood P,Rollins DE

更新日期：1981-01-01 00:00:00

abstract：PURPOSE:To review the radiofrequency ablation method, describe the technique, and discuss the indications, results, and limitations of its use in patients with cardiac tachyarrhythmias. DATA SOURCES:Peer-reviewed reports in the literature by clinical investigators who use radiofrequency catheter ablation as identified...

journal_title：Annals of internal medicine

authors： Manolis AS,Wang PJ,Estes NA 3rd

更新日期：1994-09-15 00:00:00

abstract：:The past 2 decades have seen a revolution in legal access to cannabis, driven largely by activists and business interests. As a result, the population of cannabis users nationwide-especially daily users-has grown significantly. An estimated 4.5-7 million persons in the United States now meet criteria for cannabis use ...

journal_title：Annals of internal medicine

authors： Williams AR,Hill KP

更新日期：2020-11-03 00:00:00

abstract：:Discovery of the factor V Leiden and prothrombin G20210A mutations has greatly increased the percentage of patients in whom venous thrombosis can be attributed to hereditary thrombophilia. The first step in the diagnostic approach to all patients with venous thrombosis consists of a careful history and physical examin...

journal_title：Annals of internal medicine

authors： Bauer KA

更新日期：2001-09-04 00:00:00

abstract：BACKGROUND:Mucositis can be a serious complication of cancer treatment. Palifermin reduces mucositis when given in multiple doses to patients undergoing hematopoietic stem-cell transplantation. OBJECTIVE:To evaluate the efficacy of palifermin given as a single dose before each cycle in patients receiving multicycle ch...

journal_title：Annals of internal medicine

authors： Vadhan-Raj S,Trent J,Patel S,Zhou X,Johnson MM,Araujo D,Ludwig JA,O'Roark S,Gillenwater AM,Bueso-Ramos C,El-Naggar AK,Benjamin RS

更新日期：2010-09-21 00:00:00

abstract：OBJECTIVE:To determine if polyvalent IgG is promising therapy for severe IgG nephropathy. DESIGN:Open prospective cohort study. SETTING:Referral nephrology unit. PATIENTS:11 adult patients with severe IgA nephropathy (9 who had idiopathic disease and 2 who had Henoch-Schönlein purpura) and indicators of poor prognos...

journal_title：Annals of internal medicine

authors： Rostoker G,Desvaux-Belghiti D,Pilatte Y,Petit-Phar M,Philippon C,Deforges L,Terzidis H,Intrator L,André C,Adnot S,Bonin P,Bierling P,Remy P,Lagrue G,Lang P,Weil B

更新日期：1994-03-15 00:00:00

abstract：:Data on body weight and weight change collected from nationally representative samples of U.S. adults are reviewed. The body mass index (weight [kg]/height [m2]) has a low correlation with height and is used to compare body weights between persons of differing heights. The BMI varies to a greater degree in women than ...

journal_title：Annals of internal medicine

authors： Williamson DF

更新日期：1993-10-01 00:00:00

abstract：:The indications for treating patients with subclinical hypothyroidism (normal serum thyroxine and free thyroxine levels, but elevated serum thyrotrophin levels) are poorly defined. In this study, 33 patients with subclinical hypothyroidism were randomly assigned in a double-blind manner to receive placebo or L-thyroxi...

journal_title：Annals of internal medicine

authors： Cooper DS,Halpern R,Wood LC,Levin AA,Ridgway EC

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND:The standard diagnostic approach in patients suspected of having pulmonary embolism starts with perfusion-ventilation lung scanning. If the resulting scan is not diagnostic, pulmonary angiography should be done. The use of tests for deep venous thrombosis has been advocated as an adjunct to establishing the ...

journal_title：Annals of internal medicine

authors： Turkstra F,Kuijer PM,van Beek EJ,Brandjes DP,ten Cate JW,Büller HR

更新日期：1997-05-15 00:00:00