Meta-analysis in clinical research.

abstract：:Daily change of intravenous (i.v.) infusion administration sets has been recommended by the Center for Disease Control since 1973 to reduce the risk of infusion bacteremia. To evaluate this recommendation, we undertook a prospective, randomized, controlled trial that compared the rates of i.v.-associated bacteremia, i...

journal_title：Annals of internal medicine

authors： Buxton AE,Highsmith AK,Garner JS,West CM,Stamm WE,Dixon RE,McGowan JE Jr

更新日期：1979-05-01 00:00:00

abstract：OBJECTIVE:To identify the cause of a hypersensitivity pneumonitis and to determine its pathogenesis. DESIGN:Case study. SETTING:Intensive care unit of a referral hospital. PATIENT:A 51-year-old man with chronic bronchitis who developed a hypersensitivity pneumonitis within 1 month after exposure to minocycline, amox...

journal_title：Annals of internal medicine

authors： Guillon JM,Joly P,Autran B,Denis M,Akoun G,Debré P,Mayaud C

更新日期：1992-09-15 00:00:00

abstract：:Antinuclear antibodies are present in most patients receiving procainamide. To ascertain whether IgG antiguanosine antibodies are associated with the development of the symptoms of systemic lupus erythematosus, we compared the levels of these antibodies in the sera of 65 patients receiving procainamide: 18 with procai...

journal_title：Annals of internal medicine

authors： Weisbart RH,Yee WS,Colburn KK,Whang SH,Heng MK,Boucek RJ

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:The frequency and severity of post-thrombotic sequelae after spontaneous axillary-subclavian venous thrombosis remain poorly known. OBJECTIVE:To determine the late sequelae of conventionally treated spontaneous axillary-subclavian venous thrombosis. DESIGN:Cross-sectional study. SETTING:University departm...

journal_title：Annals of internal medicine

authors： Héron E,Lozinguez O,Emmerich J,Laurian C,Fiessinger JN

更新日期：1999-10-05 00:00:00

abstract：:The association of the Epstein-Barr virus and two human malignancies, Burkitt's lumphoma and nasopharyngeal carcinoma, is reviewed. Seroepidemiologic, virologic, and immunologic evidence is summarized, and several hypotheses regarding a possible etiologic role for the Epstein-Barr virus in these tumors are presented. ...

journal_title：Annals of internal medicine

authors： Ziegler JL,Magrath IT,Gerber P,Levine PH

更新日期：1977-03-01 00:00:00

abstract：BACKGROUND:Sleep-related accidents often involve healthy young persons who are driving at night. Coffee and napping restore alertness, but no study has compared their effects on real nighttime driving performances. OBJECTIVE:To test the effects of 125 mL of coffee (half a cup) containing 200 mg of caffeine, placebo (d...

journal_title：Annals of internal medicine

authors： Philip P,Taillard J,Moore N,Delord S,Valtat C,Sagaspe P,Bioulac B

更新日期：2006-06-06 00:00:00

abstract：Background:FLU-v is a broad-spectrum influenza vaccine that induces antibodies and cell-mediated immunity. Objective:To compare the safety, immunogenicity, and exploratory efficacy of different formulations and dosing regimens of FLU-v versus placebo. Design:Randomized, double-blind, placebo-controlled, single-center...

journal_title：Annals of internal medicine

authors： Pleguezuelos O,Dille J,de Groen S,Oftung F,Niesters HGM,Islam MA,Næss LM,Hungnes O,Aldarij N,Idema DL,Perez AF,James E,Frijlink HW,Stoloff G,Groeneveld P,Hak E

更新日期：2020-04-07 00:00:00

abstract：:Common variable immunodeficiency (CVI) is a heterogenous immunodeficiency syndrome characterized by hypogammaglobulinemia, recurrent bacterial infections, and various immunologic abnormalities. In addition to recurrent infections, patients with this syndrome also have an increased incidence of autoimmune disease and m...

journal_title：Annals of internal medicine

authors： Sneller MC,Strober W,Eisenstein E,Jaffe JS,Cunningham-Rundles C

更新日期：1993-05-01 00:00:00

abstract：DESCRIPTION:Although approximately 85 million units of red blood cells (RBCs) are transfused annually worldwide, transfusion practices vary widely. The AABB (formerly, the American Association of Blood Banks) developed this guideline to provide clinical recommendations about hemoglobin concentration thresholds and othe...

journal_title：Annals of internal medicine

authors： Carson JL,Grossman BJ,Kleinman S,Tinmouth AT,Marques MB,Fung MK,Holcomb JB,Illoh O,Kaplan LJ,Katz LM,Rao SV,Roback JD,Shander A,Tobian AA,Weinstein R,Swinton McLaughlin LG,Djulbegovic B,Clinical Transfusion Medicine Com

更新日期：2012-07-03 00:00:00

abstract：:Six patients with rheumatoid arthritis developed a syndrome resembling lupus erythematosus while being treated with penicillamine. All patients had previous mucocutaneous reactions to chrysotherapy. Manifestations included pleurisy in five of six patients, rashes in three, nephritis in two, and neurologic disturbances...

journal_title：Annals of internal medicine

authors： Chalmers A,Thompson D,Stein HE,Reid G,Patterson AC

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:A survey of general internist members of the American College of Physicians (ACP) in 1986 found that they did a large number and variety of procedures in their practices. Since then, changes in the practice of medicine, regulatory requirements, and availability of subspecialists may have affected the number ...

journal_title：Annals of internal medicine

authors： Wigton RS,Alguire P,American College of Physicians.

更新日期：2007-03-06 00:00:00

abstract：BACKGROUND:The current standard initial therapies for deep venous thrombosis are low-molecular-weight heparin and unfractionated heparin. In a dose-ranging study of patients with symptomatic deep venous thrombosis, fondaparinux had efficacy and a safety profile similar to those of low-molecular-weight heparin (daltepar...

journal_title：Annals of internal medicine

authors： Büller HR,Davidson BL,Decousus H,Gallus A,Gent M,Piovella F,Prins MH,Raskob G,Segers AE,Cariou R,Leeuwenkamp O,Lensing AW,Matisse Investigators.

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:To determine the effects of fluvastatin, a synthetic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, combined with moderate alcohol consumption on lipid profiles and hepatic function in patients with primary hypercholesterolemia. DESIGN:Randomized, placebo-controlled, crossover study. S...

journal_title：Annals of internal medicine

authors： Smit JW,Wijnne HJ,Schobben F,Sitsen A,De Bruin TW,Erkelens DW

更新日期：1995-05-01 00:00:00

abstract：:Delirium is a common and distressing symptom that constitutes a significant challenge for end-of-life care. However, reliable techniques are available for the diagnosis of delirium, and effective therapies exist as well. This consensus paper uses a case-based format that begins with an overview of the definition and p...

journal_title：Annals of internal medicine

authors： Casarett DJ,Inouye SK,American College of Physicians-American Society of Internal Medicine End-of-Life Care Consensus Panel.

更新日期：2001-07-03 00:00:00

abstract：BACKGROUND:Hospitals are implementing discharge support programs to reduce readmissions, and these programs have had mixed success. OBJECTIVE:To examine whether a peridischarge, nurse-led intervention decreased emergency department (ED) visits or readmissions among ethnically and linguistically diverse older patients ...

journal_title：Annals of internal medicine

authors： Goldman LE,Sarkar U,Kessell E,Guzman D,Schneidermann M,Pierluissi E,Walter B,Vittinghoff E,Critchfield J,Kushel M

更新日期：2014-10-07 00:00:00

abstract：PURPOSE:To evaluate the use of thyroid function tests to monitor therapy in patients taking levothyroxine. DATA IDENTIFICATION:Studies published between 1966 and January 1990 were identified through computer searches and references of identified studies. STUDY SELECTION:Studies that included a careful description of ...

journal_title：Annals of internal medicine

authors： Helfand M,Crapo LM

更新日期：1990-09-15 00:00:00

abstract：:We compared the effects of quinidine and three alternate antiarrhythmic drugs on serum digoxin concentration in 63 patients before and during administration of quinidine, procainamide, disopyramide, or mexiletine. Quinidine increased digoxin concentration by at least 0.5 nmol/L in 21 of 22 patients: Mean serum digoxin...

journal_title：Annals of internal medicine

authors： Leahey EB Jr,Reiffel JA,Giardina EG,Bigger JT Jr

更新日期：1980-05-01 00:00:00

abstract：:One hundred ninety-eight patients with chronic myelogenous leukemia received marrow transplants after intensive chemotherapy and total body irradiation. Multivariate analysis showed disease status at time of transplantation to be the most powerful predictor of survival. The probability of long-term survival for alloge...

journal_title：Annals of internal medicine

authors： Thomas ED,Clift RA,Fefer A,Appelbaum FR,Beatty P,Bensinger WI,Buckner CD,Cheever MA,Deeg HJ,Doney K

更新日期：1986-02-01 00:00:00

abstract：:Flecainide acetate has a recognized proarrhythmic effect in patients treated for ventricular tachycardia. Three patients developed severe ventricular arrhythmias while taking flecainide for atrial fibrillation. Patient 1 had normal ventricular function and idiopathic atrial fibrillation. Treadmill exercise tests durin...

journal_title：Annals of internal medicine

authors： Falk RH

更新日期：1989-07-15 00:00:00

abstract：:Past efforts to reverse or limit the effects of acute stroke have been largely unsuccessful, in part because of the inability to evaluate and treat most patients soon after stroke onset. One important factor in the delay of treatment has been the nihilistic attitude of medical personnel, including physicians, toward t...

journal_title：Annals of internal medicine

authors：

更新日期：1995-04-15 00:00:00

abstract：PURPOSE:To review available information on the epidemiology, cause, diagnosis, prognosis, and treatment of acute myocardial infarction during pregnancy or in the early postpartum period and to develop guidelines for the management of this condition. DATA SOURCES:MEDLINE and Index Medicus searches and a manual search o...

journal_title：Annals of internal medicine

authors： Roth A,Elkayam U

更新日期：1996-11-01 00:00:00

abstract：OBJECTIVE:To determine whether diabetic patients, when compared with nondiabetic patients, have a higher incidence of restenosis after coronary stenting, and, if so, whether restenosis is attributable to lesion or procedural differences or to a greater biologic tendency for late loss of minimum diameter in diabetic pat...

journal_title：Annals of internal medicine

authors： Carrozza JP Jr,Kuntz RE,Fishman RF,Baim DS

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Previous meta-analyses demonstrated that high-dose glucocorticoids were not beneficial in sepsis. Recently, lower-dose glucocorticoids have been studied. PURPOSE:To compare recent trials of glucocorticoids for sepsis with previous glucocorticoid trials. DATA SOURCES:Systematic MEDLINE search for studies pu...

journal_title：Annals of internal medicine

authors： Minneci PC,Deans KJ,Banks SM,Eichacker PQ,Natanson C

更新日期：2004-07-06 00:00:00

abstract：BACKGROUND:Exercise therapy encompasses a heterogeneous group of interventions. There continues to be uncertainty about the most effective exercise approach in chronic low back pain. PURPOSE:To identify particular exercise intervention characteristics that decrease pain and improve function in adults with nonspecific ...

journal_title：Annals of internal medicine

authors： Hayden JA,van Tulder MW,Tomlinson G

更新日期：2005-05-03 00:00:00

abstract：:Active-control noninferiority trials are being performed with increasing frequency when standard placebo-controlled trials are considered unethical. Three attributes are optimally required to establish noninferiority: 1) The treatment under consideration exhibits therapeutic noninferiority to the active control; 2) th...

journal_title：Annals of internal medicine

authors： Kaul S,Diamond GA

更新日期：2006-07-04 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the usefulness and safety of hydroxychloroquine in patients with decompensated, treatment-refractory noninsulin-dependent diabetes mellitus. DESIGN:Prospective, randomized, placebo, double-blind 6-month trial. PATIENTS:Thirty-eight patients with noninsulin-dependent diabetes resistant to c...

journal_title：Annals of internal medicine

authors： Quatraro A,Consoli G,Magno M,Caretta F,Nardozza A,Ceriello A,Giugliano D

更新日期：1990-05-01 00:00:00

abstract：:The coexistence of chronic idiopathic thrombocytopenic purpura and myasthenia gravis has been infrequently reported. We report another case and show the coexistence of autoantibodies to the platelet glycoprotein IIb and IIIa complex and the acetylcholine receptor. Autoantibody levels were followed during 8 weeks of tr...

journal_title：Annals of internal medicine

authors： Anderson MJ,Woods VL Jr,Tani P,Lindstrom JM,Schmidt D,McMillan R

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:Preventive therapy is an important element of syphilis control efforts. No currently recommended, single-dose alternatives to penicillin G benzathine are available for treatment of incubating syphilis. OBJECTIVE:To evaluate the use of a single 1.0-g dose of azithromycin for treatment of persons recently exp...

journal_title：Annals of internal medicine

authors： Hook EW 3rd,Stephens J,Ennis DM

更新日期：1999-09-21 00:00:00

abstract：:Treatment advances and outcomes data have raised new concerns about how to optimize care for patients with HIV infection. This paper reviews evidence on 1) the relation between experience and type of training and patient outcomes, 2) the relation between the components of primary care and patient outcomes, and 3) prim...

journal_title：Annals of internal medicine

authors： Hecht FM,Wilson IB,Wu AW,Cook RL,Turner BJ

更新日期：1999-07-20 00:00:00

abstract：:Thirty-five consecutive patients with progressive systemic sclerosis were prospectively evaluated for evidence of Sjögren's syndrome. Six of the 35 (17%) were judged to have the disorder. This is a higher prevalence than in most reports, but much lower than that recently reportedly by Alarcón-Segovia and associates (7...

journal_title：Annals of internal medicine

authors： Cipoletti JF,Buckingham RB,Barnes EL,Peel RL,Mahmood K,Cignetti FE,Pierce JM,Rabin BS,Rodnan GP

更新日期：1977-11-01 00:00:00