Autoantibodies to platelet glycoprotein IIb/IIIa and to the acetylcholine receptor in a patient with chronic idiopathic thrombocytopenic purpura and myasthenia gravis.

abstract：:Forceful new demands for accountability in medicine are arising from many interested parties. To maintain professional standards, physicians need to establish which demands are desirable and which are not. We adopt a model of stratified accountability that includes three major components: the accountable parties, the ...

journal_title：Annals of internal medicine

authors： Emanuel LL

更新日期：1996-01-15 00:00:00

abstract：BACKGROUND:Lack of awareness of hypoglycemia is a major limiting factor in the management of type 1 diabetes. OBJECTIVE:To examine whether reduction in the number of episodes of hypoglycemia restores hypoglycemia awareness by influencing beta-adrenergic sensitivity in patients with type 1 diabetes. DESIGN:Controlled ...

journal_title：Annals of internal medicine

authors： Fritsche A,Stefan N,Häring H,Gerich J,Stumvoll M

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:To provide a rational strategy for the evaluation and long-term management of epilepsy. DATA SOURCES:Articles written between 1964 and 1993, obtained from a MEDLINE search on epilepsy-related topics as well as from the author's personal files, major reference books on antiepileptic drugs, and references iden...

journal_title：Annals of internal medicine

authors： French J

更新日期：1994-03-01 00:00:00

abstract：:Two patients with profound decrease of alpha1-antitrypsin (PiZZ) presented with severe pannicultis (Weber-Christian disease); one had systemic panniculitis including pancreatitis. Another possible case is quoted from the literature. Although milder forms of panniculitis can have normal Pi phenotypes and alpha1-antitry...

journal_title：Annals of internal medicine

authors： Rubinstein HM,Jaffer AM,Kudrna JC,Lertratanakul Y,Chandrasekhar AJ,Slater D,Schmid FR

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:The optimal strategy to prevent recurrent presumed paradoxical emboli in patients with patent foramen ovale is unknown. PURPOSE:To synthesize the current knowledge about and qualitatively assess the relative benefits of transcatheter closure versus medical therapy for patent foramen ovale. DATA SOURCES:Eng...

journal_title：Annals of internal medicine

authors： Khairy P,O'Donnell CP,Landzberg MJ

更新日期：2003-11-04 00:00:00

abstract：:During the last 2 years, the use of pulsed Doppler echocardiography for assessing left ventricular diastolic function has received increased attention. This method is based on measurements derived from a waveform that reflects the velocity of blood flow through the mitral valve during ventricular filling. The techniqu...

journal_title：Annals of internal medicine

authors： Spirito P,Maron BJ

更新日期：1988-07-15 00:00:00

abstract：BACKGROUND:Lateral epicondylitis is a common condition for which botulinum toxin has been reported to have a therapeutic role in uncontrolled studies. OBJECTIVE:To determine if an injection of botulinum toxin is more effective than placebo for reducing pain in adults with lateral epicondylitis. DESIGN:Randomized, dou...

journal_title：Annals of internal medicine

authors： Wong SM,Hui AC,Tong PY,Poon DW,Yu E,Wong LK

更新日期：2005-12-06 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the efficacy of cisplatin-based combination chemotherapy in patients with advanced ovarian germ-cell tumors. DESIGN:Nonrandom prospective trial with endpoints of tumor response, results of repeat surgical exploration, progression-free interval, and survival. SETTING:Cooperative university-...

journal_title：Annals of internal medicine

authors： Williams SD,Blessing JA,Moore DH,Homesley HD,Adcock L

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy and toxicity of moricizine in treating patients with serious ventricular arrhythmias and inducible sustained ventricular tachycardia. DESIGN:Uncontrolled clinical trial. SETTING:The intensive care and telemetry units of Northwestern Memorial Hospital, St. Francis Hospital and Medical ...

journal_title：Annals of internal medicine

authors： Damle R,Levine J,Matos J,Greenberg S,Brooks R,Frumkin W,Goldberger J,Kadish AH

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Pulmonary embolism is a common clinical disorder that is associated with high morbidity and mortality if untreated. It is important to confirm or rule out the diagnosis in patients with clinical suspicion of the disease. PURPOSE:To evaluate various diagnostic strategies for excluding pulmonary embolism. DA...

journal_title：Annals of internal medicine

authors： Kruip MJ,Leclercq MG,van der Heul C,Prins MH,Büller HR

更新日期：2003-06-17 00:00:00

abstract：BACKGROUND:Staphylococcus aureus is a common cause of serious infection in patients infected with HIV. OBJECTIVES:To evaluate risk factors for and quantitative effect of S. aureus infection in HIV-infected patients, with special attention to nasal carriage. DESIGN:Prospective, multihospital cohort study. SETTING:Thr...

journal_title：Annals of internal medicine

authors： Nguyen MH,Kauffman CA,Goodman RP,Squier C,Arbeit RD,Singh N,Wagener MM,Yu VL

更新日期：1999-02-02 00:00:00

abstract：:Ambulatory education has become an essential part of all internal medicine residencies. To develop excellent ambulatory education programs, we must thoroughly understand the opportunities available in such a setting, and the leaders in internal medicine must be willing to experiment with nontraditional locations and r...

journal_title：Annals of internal medicine

authors： Schuster BL

更新日期：1992-06-15 00:00:00

abstract：Background:FLU-v is a broad-spectrum influenza vaccine that induces antibodies and cell-mediated immunity. Objective:To compare the safety, immunogenicity, and exploratory efficacy of different formulations and dosing regimens of FLU-v versus placebo. Design:Randomized, double-blind, placebo-controlled, single-center...

journal_title：Annals of internal medicine

authors： Pleguezuelos O,Dille J,de Groen S,Oftung F,Niesters HGM,Islam MA,Næss LM,Hungnes O,Aldarij N,Idema DL,Perez AF,James E,Frijlink HW,Stoloff G,Groeneveld P,Hak E

更新日期：2020-04-07 00:00:00

abstract：OBJECTIVE:To determine the role of B19 parvovirus in red cell aplasia of patients infected with human immunodeficiency virus type 1 (HIV-1). DESIGN:Uncontrolled clinical trial, with assay of serum, peripheral blood cells, and bone marrow for virus using DNA hybridization and immunocytochemistry techniques; these assay...

journal_title：Annals of internal medicine

authors： Frickhofen N,Abkowitz JL,Safford M,Berry JM,Antunez-de-Mayolo J,Astrow A,Cohen R,Halperin I,King L,Mintzer D

更新日期：1990-12-15 00:00:00

abstract：:Determining the patient's major reasons for seeking care is of critical importance in a successful medical encounter. To study the physician's role in soliciting and developing the patient's concerns at the outset of a clinical encounter, 74 office visits were recorded. In only 17 (23%) of the visits was the patient p...

journal_title：Annals of internal medicine

authors： Beckman HB,Frankel RM

更新日期：1984-11-01 00:00:00

abstract：:Between June 1980 and September 1981 we evaluated 24 cases of endocarditis from methicillin-resistant Staphylococcus aureus. All of the cases occurred in drug addicts and all were community-acquired. The patients ranged in age from 21 to 59 years and represented an older population than that generally reported for bac...

journal_title：Annals of internal medicine

authors： Levine DP,Cushing RD,Jui J,Brown WJ

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND:A common criticism of randomized, controlled trials (RCTs) is that the enrollment process may be highly selective and those who enroll may not represent persons in the general population. The recruitment process reported in published RCTs has not been systematically evaluated. OBJECTIVE:To determine whether...

journal_title：Annals of internal medicine

authors： Gross CP,Mallory R,Heiat A,Krumholz HM

更新日期：2002-07-02 00:00:00

abstract：:A 17-year-old girl with a clinical diagnosis of adult-type juvenile rheumatoid arthritis developed a severe hepatotoxic reaction to 3.6 g of aspirin per day. This was associated with a microangiopathic anemia and transient congestive cardiac failure. She responded well to steroids, and when all laboratory test finding...

journal_title：Annals of internal medicine

authors： Sbarbaro JA,Bennett RM

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Two recent double-blind, randomized, controlled trials (RCTs) showed that oral steroids and nonsteroidal anti-inflammatory drugs have similar analgesic effectiveness for management of gout, but the trials had small sample sizes and other methodological limitations. OBJECTIVE:To compare the effectiveness and...

journal_title：Annals of internal medicine

authors： Rainer TH,Cheng CH,Janssens HJ,Man CY,Tam LS,Choi YF,Yau WH,Lee KH,Graham CA

更新日期：2016-04-05 00:00:00

abstract：:Increasingly, interventions aimed at improving care are likely to use such technologies as machine learning and artificial intelligence. However, health care has been relatively late to adopt them. This article provides clinical examples in which machine learning and artificial intelligence are already in use in healt...

journal_title：Annals of internal medicine

authors： Bates DW,Auerbach A,Schulam P,Wright A,Saria S

更新日期：2020-06-02 00:00:00

abstract：:With the renewed interest in esophageal motility disorders, diffuse esophageal spasm is being diagnosed more frequently. In many clinical settings, however, the term is used as a synonym for noncardiac chest pain. Our review of the literature and broad clinical experience in studying the motility patterns of healthy s...

journal_title：Annals of internal medicine

authors： Richter JE,Castell DO

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Motor vehicle crashes (MVCs) remain a leading cause of injury-related deaths in the United States. Primary seat belt laws allow vehicle occupants to be ticketed solely for not wearing seat belts, and secondary laws allow ticketing only for failure to wear seat belts in the setting of other violations. OBJEC...

journal_title：Annals of internal medicine

authors： Lee LK,Monuteaux MC,Burghardt LC,Fleegler EW,Nigrovic LE,Meehan WP,Schutzman SA,Mannix R

更新日期：2015-08-04 00:00:00

abstract：BACKGROUND:Health care workers are at occupational risk for a vast array of infections that cause substantial illness and occasional deaths. Despite this, few studies have examined the incidence, prevalence, or exposure-associated rates of infection or have considered infection-specific interventions recommended to mai...

journal_title：Annals of internal medicine

authors： Sepkowitz KA

更新日期：1996-11-15 00:00:00

abstract：:Sudden cardiac death remains a leading cause of death in the United States, accounting for more than 350,000 deaths each year, and the survival rate of victims remains low. Most survivors face a significant risk for recurrence. The typical substrate is chronic--abnormal myocardium with fibrosis (often from previous my...

journal_title：Annals of internal medicine

authors： Akhtar M,Garan H,Lehmann MH,Troup PJ

更新日期：1991-03-15 00:00:00

abstract：DESCRIPTION:Although approximately 85 million units of red blood cells (RBCs) are transfused annually worldwide, transfusion practices vary widely. The AABB (formerly, the American Association of Blood Banks) developed this guideline to provide clinical recommendations about hemoglobin concentration thresholds and othe...

journal_title：Annals of internal medicine

authors： Carson JL,Grossman BJ,Kleinman S,Tinmouth AT,Marques MB,Fung MK,Holcomb JB,Illoh O,Kaplan LJ,Katz LM,Rao SV,Roback JD,Shander A,Tobian AA,Weinstein R,Swinton McLaughlin LG,Djulbegovic B,Clinical Transfusion Medicine Com

更新日期：2012-07-03 00:00:00

abstract：:The diagnosis of gout depends on showing urate crystals in synovial effusions or, with less certainty, recognizing a characteristic clinical presentation. The management of gout has four phases: control of inflammation, diagnostic evaluation, education of the patient, and treatment for the hyperuricemia. Sound logical...

journal_title：Annals of internal medicine

authors： Simkin PA

更新日期：1979-05-01 00:00:00

abstract：:The management of asymptomatic hyperuricemia is controversial. Reported benefits from treatment prevention of acute gouty arthritis, chronic tophaceous gout, urolithiasis, or gouty nephropathy. A review of experimental and clinical data suggests that the risks of asymptomatic hyperuricemia are small or unknown and the...

journal_title：Annals of internal medicine

authors： Liang MH,Fries JF

更新日期：1978-05-01 00:00:00

abstract：:Sideroblastic anemia after treatment for Hogdkin's disease was seen in two patients 3 years after completion of radiation therapy and chemotherapy. This was followed in both by the development of myelomonoblastic leukemia. No evidence of recurrent Hodgkin's disease was present in either patient. Our observation sugges...

journal_title：Annals of internal medicine

authors： Kitahara M,Cosgriff TM,Eyre HJ

更新日期：1980-05-01 00:00:00

abstract：:Adult T-cell leukemia associated with human T-cell leukemia virus type I (HTLV-I) is characterized by a clonal expansion of a CD4-positive subset of T lymphocytes that constitutively express high numbers of interleukin-2 receptors and that frequently infiltrate the skin; osteolytic bone lesions, and hypercalcemia. Usi...

journal_title：Annals of internal medicine

authors： Marcon L,Rubin LA,Kurman CC,Fritz ME,Longo DL,Uchiyama T,Edwards BK,Nelson DL

更新日期：1988-08-15 00:00:00

abstract：BACKGROUND:Advice and exercise are widely recommended for subacute low back pain, but the effectiveness of these interventions is unclear. OBJECTIVE:To investigate the effectiveness of physiotherapist-prescribed exercise, advice, or both for subacute low back pain. DESIGN:Factorial randomized, placebo-controlled tria...

journal_title：Annals of internal medicine

authors： Pengel LH,Refshauge KM,Maher CG,Nicholas MK,Herbert RD,McNair P

更新日期：2007-06-05 00:00:00