Asymptomatic hyperuricemia: the case for conservative management.

Abstract:

:The management of asymptomatic hyperuricemia is controversial. Reported benefits from treatment prevention of acute gouty arthritis, chronic tophaceous gout, urolithiasis, or gouty nephropathy. A review of experimental and clinical data suggests that the risks of asymptomatic hyperuricemia are small or unknown and the efficacy of long-term treatment in preventing gout or renal disease is unproved. The costs and risks of prolonged drug administration and practical considerations such as patient compliance mitigate against long-term therapy in asymptomatic persons. We offer some recommendations for an expectant approach to the management of asymptomatic hyperuricemia.

journal_name

Ann Intern Med

authors

Liang MH,Fries JF

doi

10.7326/0003-4819-88-5-666

subject

Has Abstract

pub_date

1978-05-01 00:00:00

pages

666-70

issue

5

eissn

0003-4819

issn

1539-3704

journal_volume

88

pub_type

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