Removal of toxic levels of N-acetylprocainamide with continuous arteriovenous hemofiltration or continuous arteriovenous hemodiafiltration.

Abstract:

:Two patients with renal failure developed N-acetylprocainamide toxicity while receiving procainamide. Treatment consisted of continuous arteriovenous hemofiltration in one and hemodialysis followed by continuous arteriovenous hemodiafiltration in the other. The efficacy of these treatments was compared with the efficacy of three-times-weekly hemodialysis as used in two patients on chronic hemodialysis who had elevated N-acetylprocainamide levels. Continuous methods produced a more rapid reduction in N-acetylprocainamide levels than intermittent hemodialysis.

journal_name

Ann Intern Med

authors

Domoto DT,Brown WW,Bruggensmith P

doi

10.7326/0003-4819-106-4-550

subject

Has Abstract

pub_date

1987-04-01 00:00:00

pages

550-2

issue

4

eissn

0003-4819

issn

1539-3704

journal_volume

106

pub_type

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